Psychosocial Stress,the Unpredictability Schema,and Cardiovascular Disease in Women

作     者：Tomás Cabeza de Baca,PhD Michelle A.Albert,MD,MPH 

作者机构：Department of MedicineUniversity of CaliforniaSan Francisco505 Parnassus AvenueSan FranciscoCA 94117USA 

出 版 物：《Cardiovascular Innovations and Applications》 (心血管创新与应用（英文）)

年 卷 期：2019年第3卷第B2期

页      面：391-401页

学科分类：10[医学] 

主　　题：cardiovascular disease psychological stress depression anxiety Women unpredictability schema life history theory psychosocial stress 

摘      要：Depression/anxiety-related disorders and psychosocial stress have been implicated as cardiovascular disease(CVD)risk *** are at considerable risk for affective disorders and report greater severity from psychosocial stress,compared to *** disorders and cardiovascular disease likely share underlying pathophysiological mechanisms that are potentiated among women–especially younger *** stressors that threaten the safety,security,and status of an individual are appraised by the brain,producing a cascade of evoked physiological and cognitive *** the short term,these processes overcome stressors,but come with long-term health *** psychosocial stress leads to a dysregulation of the stress response systems that can lead to a heightened stress appraisal schema called the unpredictability schema,a construct that might arguably place women at heightened risk for CVD.