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Blending with transition metals improves bioresorbable zinc as better medical implants

生物活性材料(英文) 2023年第2期20卷 243-258页

作者： Yingchao Su Jiayin Fu Juncen Zhou elias Georgas Shaokang Du Yi-Xian Qin Yadong Wang Yufeng Zheng Donghui Zhu Department of biomedical engineering Stony Brook UniversityStony BrookNYUSA nancy e.and peter c.meinig school of biomedical engineering Cornell UniversityIthacaNYUSA Department of cardiology Sir Run Run Shaw HospitalZhejiang UniversityHangzhouZhejiangChina Academy for Advanced Interdisciplinary Studies Peking UniversityBeijingChina school of Materials Science.and engineering Peking UniversityBeijingChina

Zinc(Zn)is a new class of bioresorbable metal that has potential for cardiovascular stent material,orthopedic implants,wound closure devices,etc.However,pure Zn is not ideal for these applications due to its low mechanical strength and localized degradation behavior.Alloying is the most common/effective way to overcome this limitation.Still,the choice of alloying element is crucial to ensure the resulting alloy possesses sufficient mechanical strength,suitable degradation rate.and acceptable biocompatibility.Hereby,we proposed to blend selective transition metals(i.e.,vanadium-V,chromium-cr,and zirconium-Zr)to improve Zn’s properties.These selected transition metals have similar properties to Zn and thus are beneficial for the metallurgy process and mechanical property.Furthermore,the biosafety of these elements is of less concern as they all have been used as regulatory approved medical implants or a component of an implant such as Ti6Al4V,cocr,or Zr-based dental implants.Our study showed the first evidence that blending with transition metals V,cr,or Zr can improve Zn’s properties as bioresorbable medical implants.In addition,three in vivo implantation models were explored in rats:subcutaneous,aorta,and femoral implantations,to target the potential clinical applications of bioresorbable Zn implants.

关键词： Degradation cardiovascular Orthopedic Subcutaneous Antibacterial

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Improved mechanical, degradation, and biological performances of Zn–Fe alloys as bioresorbable implants

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Bioactive Materials 2022年第11期7卷 334-343页

作者： Yingchao Su Jiayin Fu Wonsae Lee Shaokang Du Yi-Xian Qin Yufeng Zheng Yadong Wang Donghui Zhu Department of biomedical engineering Stony Brook UniversityStony BrookNYUSA nancy e.and peter c.meinig school of biomedical engineering Cornell UniversityIthacaNYUSA Department of cardiology Sir Run Run Shaw HospitalZhejiang UniversityHangzhouZhejiangChina Academy for Advanced Interdisciplinary Studies Peking UniversityBeijingChina school of Materials Science.and engineering Peking UniversityBeijingChina

Zinc(Zn)is a promising bioresorbable implant material with more moderate degradation rate compared to magnesium(Mg)and iron(Fe).However,the low mechanical strength and localized degradation behavior of pure Zn limit its clinical applications.Alloying is one of the most effective ways to overcome these limitations.After screening the alloying element candidates regarding their potentials for improvement on the degradation and biocompatibility,we proposed Fe as the alloying element for Zn,and investigated the in vitro and in vivo performances of these alloys in both subcutaneous and femoral tissues.Results showed that the uniformly distributed secondary phase in Zn–Fe alloys significantly improved the mechanical property and facilitated uniform degradation,which thus enhanced their biocompatibility,especially the Zn-0.4Fe alloy.Moreover,these Zn–Fe alloys showed outstanding antibacterial property.Taken together,Zn–Fe alloys could be promising can-didates as bioresorbable medical implants for various cardiovascular,wound closure.and orthopedic applications.

关键词： Zinc Mechanical Degradation Biocompatibility Antibacterial

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Bone Regeneration Based on Tissue engineering conceptions – A 21st century Perspective

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Bone Research 2013年第3期1卷 216-248页

作者： Jan Henkel Maria A.Woodruff Devakara R.epari Roland Steck Vaida Glatt Ian c.Dickinson peter F.M.choong Michael A.Schuetz Dietmar W.Hutmacher Institute of Health & biomedical Innovation Queensland University of TechnologyBrisbane Queensland Australia Orthopaedic Oncology Service Princess Alexandra HospitalBrisbane Australia Department of Surgery University of Melbourne St. Vincent's HospitalMelbourne Australia Department of Orthopaedics St. Vincent's HospitalMelbourneAustralia Bone.and Soft Tissue Sarcoma Service Peter MacCallum Cancer CentreMelbourne Australia Orthopaedic and Trauma Services Princess Alexandra HospitalBrisbane Australia George W Woodruff school of Mechanical engineering Georgia Institute of TechnologyAtlanta GA USA

The role of Bone Tissue engineering in the field of Regenerative Medicine has been the topic of substantial research over the past two decades. Technological advances have improved orthopaedic implants and surgical techniques for bone reconstruction. However, improvements in surgical techniques to reconstruct bone have been limited by the paucity of autologous materials available.and donor site morbidity. Recent advances in the development of biomaterials have provided attractive alternatives to bone grafting expanding the surgical options for restoring the form and function of injured bone. Specifically, novel bioactive （second generation） biomaterials have been developed that are characterised by controlled action and reaction to the host tissue environment, whilst exhibiting controlled chemical breakdown and resorption with an ultimate replacement by regenerating tissue. Future generations of biomaterials （third generation） are designed to be not only osteo- conductive but also osteoinductive, i.e. to stimulate regeneration of host tissues by combining tissue engineer- ing and in situ tissue regeneration methods with a focus on novel applications. These techniques will lead to novel possibilities for tissue regeneration and repair. At present, tissue engineered constructs that may find future use as bone grafts for complex skeletal defects, whether from post-traumatic, degenerative, neoplastic or congenital/developmental ＂origin＂ require osseous reconstruction to ensure structural and functional integrity. engineering functional bone using combinations of cells, scaffolds and bioactive factors is a promising strategy and a particular feature for future development in the area of hybrid materials which are able to exhibit suitable biomimetic and mechanical properties. This review will discuss the state of the art in this field and what we can expect from future generations of bone regeneration concepts.

关键词： bone tissue engineering regenerative medicine additve manufacturing clinical translation scaffolds

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High-resolution two-photon transcranial imaging of brain using direct wavefront sensing

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Photonics Research 2021年第6期9卷 1144-1156页

作者： cONGPING cHeN ZHONGYA QIN SIcONG He SHAOJUN LIU SHUN-FAT LAU WANJIe WU DAN ZHU nancy Y.IP JIANAN Y.QU Department of electronic and computer engineering The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina State Key Laboratory of Molecular Neuroscience The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina center of Systems Biology and Human Health The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina Britton chance center for biomedical Photonics Wuhan National Laboratory for OptoelectronicsHuazhong University of Science and TechnologyWuhanChina Moe Key Laboratory for biomedical Photonics Collaborative Innovation Center for Biomedical EngineeringSchool of Engineering SciencesHuazhong University of Science and TechnologyWuhanChina Division of Life Science The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina Molecular Neuroscience center The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina

Imaging of the brain in its native state at high spatial resolution poses major challenges to visualization techniques.Two-photon microscopy integrated with the thinned-skull or optical clearing skull technique provides a minimally invasive tool for in vivo imaging of the cortex of mice without activating immune response.and inducing brain injury.However,the imaging contrast and spatial resolution are severely compromised by the optical heterogeneity of the skull,limiting the imaging depth to the superficial layer.In this work,an optimized configuration of an adaptive optics two-photon microscope system and an improved wavefront sensing algorithm are proposed for accurate correction for the aberrations induced by the skull window and brain tissue.Using this system,we achieved subcellular resolution transcranial imaging of layer 5 pyramidal neurons up to 700μm below pia in living mice.In addition,we investigated microglia–plaque interaction in living brain of Alzheimer’s disease.and demonstrated high-precision laser dendrotomy and single-spine ablation.

关键词： resolution photon system

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Design and Development of a High-Throughput System for Learning and Memory Research on Zebrafish

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Journal of Behavioral and Brain Science 2018年第6期8卷 351-368页

作者： Hamed Hanafi Alamdari nancy Kilcup Zachary Ford Florentin Wilfart David c. Roach Michael Schmidt school of biomedical engineering Dalhousie University Halifax Canada Rowe school of Business Dalhousie University Halifax Canada Department of Medical Sciences Dalhousie University Halifax Canada Department of Anaesthesia Dalhousie University Halifax Canada

Background: Since 2004, zebrafish have become the state-of-the-art, in vivo model for biomedical research due to their genetic and physiological homology with humans, inexpensive high-quantity breeding, and quick development in a highly-controlled environment suitable for longitudinal studies. New Method: To fully utilize the zebrafish model, a novel, automated, high-throughput system was designed. Shoals of five zebrafish were placed in 16 tanks and automatically fed over two days for a total of 16 training sessions. color LeD lights were used as the stimulus for each shoal coinciding with the release of food for a duration of 20 seconds. This system was tested on two age groups: 6- and 11-month-old. Results: After three training sessions, the median height of the school in the tank during stimulus was significantly higher than that of the naïve fish during the first training session. All subsequent training sessions demonstrated similar behaviour. A decline in memory retention, as defined by a reduction in the median height during light stimulus (i.e. no simultaneous food delivery), was observed 8 days post training. comparison with existing methods: The high-throughput nature of this system allows for simultaneous training of 16 tanks of fish under identical conditions without human interaction and provides a means to rapidly assess their learning and memory behaviours. conclusion: Results provide a baseline for understanding the normal cognitive processes of learning and memory retention in zebrafish. This work paves the way for future studies on the impacts of therapeutic agents on these cognitive processes.

关键词： Learning Behavior High Throughput System Automation cognition

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The Genome of Artemisia annua Provides Insight into the evolution of Asteraceae Family and Artemisinin Biosynthesis

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Molecular Plant 2018年第6期11卷 776-788页

作者： Qian Shen Lida Zhang Zhihua Liao Shengyue Wang Tingxiang Yan Pu Shi Meng Liu Xueqing Fu Qifang Pan Yuliang Wang Zongyou Lv Xu Lu Fangyuan Zhang Weimin Jiang Yanan Ma Minghui chen Xiaolong Hao Ling Li Yueli Tang Gang Lv Yan Zhou Xiaofen Sun peter e. Brodelius Jocelyn K.c. Rose Kexuan Tang Joint International Research Laboratory of Metabolic & Developmental Sciences Key Laboratory of Urban Agriculture (South) Ministry of Agriculture Plant Biotechnology Research Center Fudan-SJTU-Nottingham Plant Biotechnology R&D Center School of Agriculture and Biology Shanghai Jiao Tong University Shanghai 200240 China SWU-TAAHc Medicinal Plant Joint R&D centre School of Life Sciences Southwest University Chongqing 400715 China chinese National Human Genome center at Shanghai Shanghai 201203 China Plant Biology Section School of Integrative Plant Science Cornell University Ithaca NY 14853 USA Department of chemistry and biomedical Sciences Linnaeus University 39182 Kalmar Sweden State Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing 211198 China

Artemisia annua, commonly known as sweet wormwood or Qinghao, is a shrub native to china and has long been used for medicinal purposes. A. annua is now cultivated globally as the only natural source of a potent anti-malarial compound, artemisinin. Here, we report a high-quality draft assembly of the 1.74-gigabase genome of A. annua, which is highly heterozygous, rich in repetitive sequences, and contains 63 226 protein-coding genes, one of the largest numbers among the sequenced plant species. We found that, as one of a few sequenced genomes in the Asteraceae, the A. annua genome contains a large number of genes specific to this large angiosperm clade. Notably, the expansion and functional diversification of genes encoding enzymes involved in terpene biosynthesis are consistent with the evolution of the artemi- sinin biosynthetic pathway. We further revealed by transcriptome profiling that A. annua has evolved the sophisticated transcriptional regulatory networks underlying artemisinin biosynthesis. Based on compre- hensive genomic and transcriptomic analyses we generated transgenic A. annua lines producing high levels of artemisinin, which are now ready for large-scale production and thereby will help meet the chal- lenge of increasing global de.and of artemisinin.

关键词： Artemisia annua artemisinin genome evolution transcriptome metabolic engineering

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Atomic force microscopy reveals new mechanisms of increased aortic stiffness in hypertension

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泸州医学院学报 2013年第3期36卷 310-311页

作者： Gerald A.Meininger nancy L.Sehgel Zhu Yi Sun Zhe Hong Zhongkui Michael A.Hill Gao Shumin Jerome P.Trzeciakowski William c.Hunter Dorothy e.Vatner Stephen F.Vatner Dalton cardiovascular Research center and Department of Medical Pharmacology and Physiology University of MissouriColumbiaMOUSA Department of cell Biology and Molecular Medicine UMDNJ-New Jersey Medical SchoolNewarkNJUSA Department of biomedical engineering New Jersey Institute of TechnologyNewarkNJUSA Department of Systems Biology and Translational Medicine Texas A&M UniversityCollege StationTXUSA

Hypertension is an important global health problem that continues increase in incidence.Increased vascularstiffness has been identified as an important component of the pathogenesis of hypertension(HT).Based on theresults of recent Framingham studies,it appears that aortic increased stiffness may precede hypertension suggest-ing that controlling arterial stiffness may

关键词：发病机制高血压原子力显微镜主动脉僵硬健康问题组成部分药物治疗

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Abstracts from the 15th International Myopia conference

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eye.and Vision 2016年第1期3卷 211-221页

作者： Ale.andra Benavente-Perez Ann Nour Tobin Ansel Kathleen Abarr Luying Yan Keisha Roden David Troilo chanyi Lu Miaozhen Pan Min Zheng Jia Qu Xiangtian Zhou christine F. Wildsoet Fan Lu Jie chen Jinhua Bao Liang Hu Qinmei Wang Zibing Jin Frances Rucker Stephanie Britton Stephan Hanowsky Molly Spatcher Hui-Ying Kuo ching-Hsiu Ke I-Hsin Kuo chien-chun Peng Han-Yin Sun Ian G. Morgan Jeremy A. Guggenheim Rupal L. Shah cathy Williams Jinglei Yang peter S. Reinach Sen Zhang Wenfeng Sun Bo Liu Fen Li Xiaoqing Li Aihua Zhao Tianlu chen Wei Jia Jun Jiang Haoran Wu Kazuo Tsubota Hiroko Ozawa Hidemasa Torii Shigemasa Takamizawa Toshihide Kurihara Kazuno Negishi Klaus Graef Daniel Rathbun Frank Schaeffel Ladan Ghodsi William K. Stell Machelle T. Pardue Ranjay chakraborty Han na Park curran S. Sidhu P. Michael Iuvone Michael J collins Nethrajeith Srinvasalu Sally A. McFadden Paul N. Baird Pablo Artal Pauline cho SW cheung Pei-chang Wu Quan V. Hoang Duk c. Lee erica G. Landis Michael A. Bergen curran Sidhu Samer Hattar Richard A. Stone Ravi Metlapally Ruiqin Li Qinglin Xu Hong Zhong chenglin Pan Weizhong Lan Xiaoning Li Ling chen Zhikuan Yang Scott A. Read Seang-Mei Saw Shi-Jun Weng Xiao-Hua Wu Kang-Wei Qian Yun-Yun Li Guo-Zhong Xu Furong Huang Xiong-Li Yang Yong-Mei Zhong earl L Smith, III Baskar Arumugam Li-Fang Hung Lisa A. Ostrin Klaus Trier Monica Jong Brien A. Holden Thomas chuen Lam Samantha Shan Bing Zuo Dennis Yan-yin Tse Jingfang Bian King-Kit Li Quan Liu chi-ho To Timothy J. Gawne John T. Siegwart, Jr. Ale.ander H. Ward Thomas T. Norton Yan Zhang Yue Liu carol Ho eileen Phan Abraham Hang emily eng christine Wildsoet Department of Biological Sciences SUNY College of Optometry New York NY 10036 USA school of Optometry and Ophthalmology and eye Hospital Wenzhou Medical University Wenzhou Zhejiang 325027 China center for eye Disease & Development School of Optometry & Vision Science Program University of California Berkeley Berkeley CA 94720-2020 USA Wenzhou Medical University Wenzhou Zhejiang 325027 China biomedical Science.and Disease New England College of Optom Boston MA USA school of Optometry Chung Shan Medical University Taichung City 402 Taiwan Institute of Medicine Chung Shan Medical University Taichung City 402 Taiwan Division of Biochemistry and Molecular Biology Research School of Biology Australian National University Canberra Australia State Key Laboratory of Ophthalmology and Division of Preventive Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangzhou China school of Optometry & Vision Sciences Cardiff University Cardiff UK school of Social and community Medicine University of Bristol Bristol UK school of and eye Hospital Wenzhou Medical University Wenzhou Zhejiang 325027 China State Key Laboratory cultivation Base.and Key Laboratory of Vision Science Ministry of Health and Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry Wenzhou Zhejiang 325027 People’s Republic of China Shanghai Key Laboratory of Diabetes Mellitus and center for Translational Medicine Shanghai Jiao Tong University Affiliated Sixth People’s Hospital Shanghai 200233 China eye Hospital of Wenzhou Medical University Wenzhou Zhejiang 325027 China Department of Ophthalmology Keio University School of Medicine Shinjuku-ku Tokyo 160-8582 Japan General Medicine Ichikawa Medical Center Urayasu City Chiba 279-0001 Japan Ophthalmic Research Institute University of Tuebingen 72076 Tuebingen Germany Bernstein center for computational Neuroscience Tuebingen 72076 Tuebingen Germany Werner Reichardt centre for Integrative Neuroscience Otfried-Mueller-Straße 25 Tueb

To assess the peripheral refractive changes that occur when eye growth decelerates in marmosets.Methods We measured peripheral refraction and on-axis vitreous chamber depth on a total of 53 marmosets;36 treated monocularly for 12 weeks 9 hrs/day(26 with-5 D contact lenses,10 with+5 D)and 17 untreated controls.From the 26 marmosets treated with-5 D,10 wore contact lenses 9 hrs/day without interruptions and were mea-sured at the end of 10 weeks of treatment(T10)and after 4 weeks of recovery(R14).eight had both contact lenses removed for 30 mins twice/day(mid-morning and mid-afternoon)during the first four weeks of treatment(early interruption group)and eight had the lenses removed during the second four weeks of treatment(late interruption group).The two interruption groups were measured after 4,8 and 12 weeks of treatment only(T4,T8,T12).

关键词： removed treatment untreated

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Fungal diversity notes 1151-1276:taxonomic and phylogenetic contributions on genera and species of fungal taxa

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Fungal Diversity 2020年第1期100卷 5-277页

作者： Kevin DHyde Yang Dong Rungtiwa Phookamsak Rajesh Jeewon DJayarama Bhat eBGareth Jones Ning‑Guo Liu Pranami DAbeywickrama Ausana Mapook Deping Wei Rekhani HPerera Ishara SManawasinghe Dhandevi Pem Digvijayini Bundhun Anuruddha Karunarathna Anusha Hekanayaka Dan‑Feng Bao Junfu Li Milan cSamarakoon Napalai chaiwan chuan‑Gen Lin Kunthida Phutthacharoen Sheng‑Nan Zhang Indunil cSenanayake Ishani DGoonasekara Kasun MThambugala chayanard Phukhamsakda Danushka STennakoon Hong‑Bo Jiang Jing Yang Ming Zeng Naruemon Huanraluek Jian‑Kui(Jack)Liu Subodini NWijesinghe Qing Tian Saowaluck Tibpromma Rashika SBrahmanage Saranyaphat Boonmee Shi‑Ke Huang Vinodhini Thiyagaraja Yong‑Zhong Lu Ruvishika SJayawardena Wei Dong er‑Fu Yang Sanjay KSingh Shiv Mohan Singh Shiwali Rana Sneha SLad Garima Anand Bandarupalli Devadatha MNiranjan VVenkateswara Sarma Kare Liimatainen 馻‑ Tuula Niskanen Andy Overall Renato Lúcio Mendes Alvarenga Tatiana Baptista Gibertoni Walter PPfliegler enikőHorváth Ale.andra Imre Amanda Lucia Alves Ana carla da Silva Santos Patricia Vieira Tiago Timur SBulgakov Dhanushaka NWanasinghe Ali HBahkali Mingkwan Doilom Abdallah Melgorban Sajeewa SNMaharachchikumbura Kunhiraman cRajeshkumar Danny Haelewaters peter eMortimer Qi Zhao Saisamorn Lumyong Jianchu Xu Jun Sheng Key Laboratory for Plant Diversity and Biogeography of east Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina State Key Laboratory for conservation and Utilization of Bio‑Resources in Yunnan Yunnan Agricultural UniversityKunming 650201China Yunnan Research Institute for Local Plateau Agriculture.and Industry Kunming 650201China Key Laboratory for Agro‑biodiversity and Pest control of Ministry of education Yunnan Agricultural UniversityKunming 650201China center of excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand east and central Asia Regional Office World Agroforestry Centre(ICRAF)Kunming 650201YunnanChina centre for Mountain Futures(cMF) Kunming Institute of BotanyKunming 650201YunnanChina Mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand Department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius No.128/1‑J Azad Co‑Op Housing SocietyCurcaGoa Velha 403108India Department of entomology and Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Department of Botany and Microbiology College of ScienceKing Saud UniversityP.O.Box 2455Riyadh 11451Kingdom of Saudi Arabia school of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Faculty of Agriculture National Resources and EnvironmentNaresuan UniversityPhitsanulok 65000Thailand Beijing Key Laboratory of environment Friendly Management on Fruit Diseases and Pests in North china Institute of Plant and Environment ProtectionBeijing Academy of Agriculture and Forestry SciencesBeijing 100097China Department of Soil ecology UFZ-Helmholtz Centre for Environmental ResearchHalleGermany Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina Shenzhen Key Laboratory of Microbial Genetic engineering College of Life Sciences and OceanographyShenzhen UniversityShenzhen 518060China Department of Plant M

Fungal diversity notes is one of the important journal series of fungal taxonomy that provide detailed descriptions and illustrations of new fungal taxa,as well as providing new information of fungal taxa worldwide.This article is the 11th contribution to the fungal diversity notes series,in which 126 taxa distributed in two phyla,six classes,24 orders and 55 families are described and illustrated.Taxa in this study were mainly collected from Italy by erio camporesi and also collected from china,India and Thailand,as well as in some other european,North American and South American countries.Taxa described in the present study include two new families,12 new genera,82 new species,five new combinations and 25 new records on new hosts and new geographical distributions as well as sexual-asexual reports.The two new families are eriomycetaceae(Dothideomycetes,family incertae sedis)and Fasciatisporaceae(Xylariales,Sordariomycetes).The twelve new genera comprise Bhagirathimyces(Phaeosphaeriaceae),camporesiomyces(Tubeufiaceae),eriocamporesia(cryphonectriaceae),eriomyces(eriomycetaceae),Neomonodictys(Pleurotheciaceae),Paraloratospora(Phaeosphaeriaceae),Paramonodictys(Parabambusicolaceae),Pseudoconlarium(Diaporthomycetidae,genus incertae sedis),Pseudomurilentithecium(Lentitheciaceae),Setoapiospora(Muyocopronaceae),Srinivasanomyces(Vibrisseaceae.and Xenoanthostomella(Xylariales,genera incertae sedis).The 82 new species comprise Acremonium chiangraiense,Adustochaete nivea,Angustimassarina camporesii,Bhagirathimyces himalayensis,Brunneoclavispora camporesii,camarosporidiella camporesii,camporesiomyces mali,camposporium appendiculatum,camposporium multiseptatum,camposporium septatum,canalisporium aquaticium,clonostachys eriocamporesiana,clonostachys eriocamporesii,colletotrichum hederiicola,coniochaeta vineae,conioscypha verrucosa,cortinarius ainsworthii,cortinarius aurae,cortinarius britannicus,cortinarius heatherae,cortinarius scoticus,cortinarius subsaniosus,cytospora fusispora,cytospora rosigena,Diaporthe camporesii,Diapor

关键词： 96 new taxa Agaricomycetes Ascomycota Basidiomycota Dothideomycetes Lecanoromycetes Leotiomycetes Pezizomycetes Phylogeny Saccharomycetes Taxonomy

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The Global Soil Mycobiome consortium dataset for boosting fungal diversity research

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Fungal Diversity 2021年第6期111卷 573-588页

作者： Leho Tedersoo Vladimir Mikryukov Sten Anslan Mohammad Bahram Abdul Nasir Khalid Adriana corrales Ahto Agan Aída-M.Vasco-Palacios Alessandro Saitta Ale.andre Antonelli Andrea c.Rinaldi Annemieke Verbeken Bobby P.Sulistyo Boris Tamgnoue Brendan Furneaux camila Duarte Ritter casper Nyamukondiwa cathy Sharp césar Marín D.Q.Dai Daniyal Gohar Dipon Sharmah elisabeth Machteld Biersma erin K.cameron eske De crop eveli Otsing evgeny A.Davydov Felipe e.Albornoz Francis Q.Brearley Franz Buegger Genevieve Gates Geoffrey Zahn Gregory Bonito Indrek Hiiesalu Inga Hiiesalu Irma Zettur Isabel c.Barrio Jaan Pärn Jacob Heilmann-clausen Jelena Ankuda John Y.Kupagme Joosep Sarapuu Jose G.Maciá-Vicente Joseph Djeugap Fovo József Geml Juha M.Alatalo Julieta Alvarez-Manjarrez Jutamart Monkai Kadri Põldmaa Kadri Runnel Kalev Adamson Kari A.Bråthen Karin Pritsch Kassim I.Tchan Kęstutis Armolaitis Kevin D.Hyde Kevin K.Newsham Kristel Panksep Lateef A.Adebola Louis J.Lamit Malka Saba Marcela eda Silva cáceres Maria Tuomi Marieka Gryzenhout Marijn Bauters Miklós Bálint Nalin Wijayawardene Niloufar Hagh-Doust Nourou S.Yorou Olavi Kurina peter e.Mortimer peter Meidl RHenrik Nilsson Rasmus Puusepp Rebeca casique-Valdés Rein Drenkhan Roberto Garibay-Orijel Roberto Godoy Saleh Alfarraj Saleh Rahimlou Sergei Põlme Sergey V.Dudov Sunil Mundra Talaat Ahmed Tarquin Netherway Terry W.Henkel Tomas Roslin Vladimir e.Fedosov Vladimir G.Onipchenko WAe.andi Yasanthika Young Woon Lim Meike Piepenbring Darta Klavina Urmas Kõljalg Kessy Abarenkov Mycology and Microbiology center University of TartuTartuEstonia Institute of ecology and earth Sciences TartuEstonia Department of ecology Swedish University of Agricultural SciencesUppsalaSweden Department of Botany University of the PunjabQuaid-e-Azam CampusLahorePakistan centro de Investigaciones en Microbiología y Biotecnología-UR(cIMBIUR) Facultad de Ciencias NaturalesUniversidad del RosarioBogotáColombia Grupo de Microbiología Ambiental y BioMicro Escuela de MicrobiologíaUniversidad de Antioquia UdeAMedellínColombia Department of Agricultural Food and Forest SciencesUniversity of PalermoPalermoItaly Royal Botanic Gardens SurreyUK Department of biomedical Sciences University of CagliariCagliariItaly Research Group Mycology Department of BiologyGhent UniversityGhentBelgium Department of Biomedicine Indonesia International Institute for Life SciencesJakartaIndonesia Plant Pathology and Agricultural Zoology Research Unit Department of Plant ProtectionFaculty of Agronomy and Agricultural SciencesUniversity of DschangDschangCameroon Department of ecology and Genetics Uppsala UniversityUppsalaSweden eukaryotic Microbiology University of Duisburg-EssenEssenGermany Department of Biological Sciences and Biotechnology Botswana International University of Science and TechnologyPalapyeBotswana Natural History Museum of Zimbabwe BulawayoZimbabwe Institute of Botany Czech Academy of SciencesPrůhoniceCzech Republic center for Yunnan Plateau Biological Resources Protection and Utilization College of Biological Resource and Food EngineeringQujing Normal UniversityQujingPeople’s Republic of China Department of Botany Jawaharlal Nehru Rajkeeya MahavidyalayaPondicherry UniversityPort BlairIndia British Antarctic Survey NERCCambridgeUK Natural History Museum of Denmark University of CopenhagenCopenhagenDenmark Department of environmental Science Saint Mary’s UniversityHalifaxNSCanada Altai State University BarnaulRussia cSIRO Land and Water WembleyWAAustralia Department of N

Fungi are highly important biotic components of terrestrial ecosystems,but we still have a very limited understanding about their diversity and distribution.This data article releases a global soil fungal dataset of the Global Soil Mycobiome consortium(GSMc)to boost further research in fungal diversity,biogeography and macroecology.The dataset comprises 722,682 fungal operational taxonomic units(OTUs)derived from PacBio sequencing of full-length ITS and 18S-V9 variable regions from 3200 plots in 108 countries on all continents.The plots are supplied with geographical and edaphic metadata.The OTUs are taxonomically and functionally assigned to guilds and other functional groups.The entire dataset has been corrected by excluding chimeras,index-switch artefacts and potential contamination.The dataset is more inclusive in terms of geographical breadth and phylogenetic diversity of fungi than previously published data.The GSMc dataset is available over the PlutoF repository.

关键词： Soil fungi Global dataset PacBio sequencing Fungal richness

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