检索结果-南通市图书馆

Neural Regeneration Research 2011年第25期6卷 1965-1970页

作者： Daxing Wu Ying Zhao Jian Liao Huifang Yin Wei Wang Medical Psychological Research Institute Second Xiangya Hospital of Central South University Changsha 410011 Hunan Province China Department of Radiology Third Xiangya Hospital of Central South University Changsha 410013 Hunan Provionce China

voxel-based morphometry-diffeomorphic anatomical registration using exponentiated lie algebra analysis was used to investigate the structural characteristics of white matter in young males with antisocial personality disorder （APD） and healthy controls without APD. The results revealed that APD subjects, relative to healthy subjects, exhibited increased white matter volume in the bilateral prefrontal lobe, right insula, precentral gyrus, bilateral superior temporal gyrus, right postcentral gyrus, right inferior parietal Iobule, right precuneus, right middle occipital lobe, right parahippocampal gyrus and bilateral cingulate, and decreased volume in the middle temporal cortex and right cerebellum. The white matter volume in the medial frontal gyrus was significantly correlated with antisocial type scores on the Personality Diagnostic Questionnaire in APD subjects. These experimental findings indicate that white matter abnormalities in several brain areas may contribute to antisocial behaviors in APD subjects.

关键词： white matter frontal lobe antisocial personality disorder voxel-based morphometry neuroimaging

Volume Gain of Brainstem on Medication-Overuse Headache Using voxel-based morphometry

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2018年第18期131卷 2158-2163页

作者： Zhioye Chen Xiao-Yan Chen Meng-Qi Liu Lin Ma Sheng-Yuan Yu Department of Radiology Chinese People's Liberation Army General Hospital Beijing 100853 China Department of Radiology Hainan Branch of Chinese People's Liberation Army General Hospital Sanya Hainan 572013 China Department of Neurology Chinese People's Liberation Army General Hospital Beijing 100853 China

Background： Histopathology identified the anatomical and molecular abnormalities ofbrainstem nuclei in migraine patients. However, the exact whole brainstem structural changes in vivo have not yet been identified in medication-overuse headache （MOH） transformed from migraine. The aim of this study was to investigate the regional volume changes over the whole brainstem in the MOH patients using voxel-based morphometry （VBM） in ***： High-resolution three-dimensional structural images were obtained using a 3.0-Tesla magnetic resonance system from 36 MOH patients and 32 normal controls （NCs） who were consecutively recruited from the International Headache Center, Chinese People＇s Liberation Army General Hospital, from March 2013 to June 2016. VBM was used to assess the brainstem structural alteration in the MOH patients, and voxel-wise correlation was performed to evaluate the relationship with the clinical ***： The brainstem region with increased volume located in the left ventrolateral periaqueductal gray （MNI coordinate： -1, -33, -8）, ventral tegmental area （MNI coordinate： 0, -22, - 12）, bilateral substantia nigra （MNI coordinate： -8, - 16, - 12, 9, - 16, - 12）, and trigeminal root entry zone （MNI coordinate： -19, -29, -31; 19, -32, -29） in MOH patients compared with NCs. The headache visual analog scale score was positively related with the left rostral ventromedial medulla （RVM）（MNI coordinate： -1, -37, -56; cluster size： 20; r = 0.602） in the MOH ***： The regional volume gain ofbrainstem could underlie the neuromechanism of impaired ascending and descending pathway in the MOH patients, and the left RVM volume alteration could imply the impaired tolerance ofnociceptive pain input and could be used to assess the headache disability in the MOH patients.

关键词： Medication-Overuse Headache Substantia Nigra Trigeminal Root Entry Zone Ventral Tegmental Area voxel-based morphometry

Brain structure in post-traumatic stress disorder A voxel-based morphometry analysis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2013年第26期8卷 2405-2414页

作者： Liwen Tan Li Zhang Rongfeng Qi Guangming Lu Lingjiang Li Jun Liu Weihui Li Mental Health Institute of the Second Xiangya Hospital Central South UniversityKey Laboratory of Psychiatry and Mental Health of Hunan Province Hunan Province Technology Institute of Psychiatry Department of Medical Imaging Jinling Hospital Clinical School of Medical College Nanjing University Department of Radiology the Second Xiangya Hosipital Central South University School of Public Administration Central South University

This study compared the difference in brain structure in 12 mine disaster survivors with chronic post-traumatic stress disorder, 7 cases of improved post-traumatic stress disorder symptoms, and 14 controls who experienced the same mine disaster but did not suffer post-traumatic stress disorder, using the voxel-based morphometry method. The correlation between differences in brain structure and post-traumatic stress disorder symptoms was also investigated. Results showed that the gray matter volume was the highest in the trauma control group, followed by the symptoms-improved group, and the lowest in the chronic post-traumatic stress disorder group. Compared with the symptoms-improved group, the gray matter volume in the lingual gyrus of the right occipital lobe was reduced in the chronic post-traumatic stress disorder group. Compared with the trauma control group, the gray matter volume in the right middle occipital gyrus and left middle frontal gyrus was reduced in the symptoms-improved group. Compared with the trauma control group, the gray matter volume in the left superior parietal lo- bule and right superior frontal gyrus was reduced in the chronic post-traumatic stress disorder group. The gray matter volume in the left superior parietal Iobule was significantly positively correlated with the State-Trait Anxiety Inventory subscale score in the symptoms-improved group and chronic post-traumatic stress disorder group （r = 0.477, P = 0.039）. Our findings indicate that （1） chronic post-traumatic stress disorder patients have gray matter structural damage in the prefrontal lobe, oc- cipital lobe, and parietal lobe, （2） after post-traumatic stress, the disorder symptoms are improved and gray matter structural damage is reduced, but cannot recover to the trauma-control level, and （3） the superior parietal Iobule is possibly associated with chronic post-traumatic stress disorder. Post-traumatic stress disorder patients exhibit gray matter abnormalities.

关键词： neural regeneration neuroimaging MRI post-traumatic stress disorder voxel-based morphometry pre-frontal lobe parietal lobe occipital lobe follow-ups grants-supported paper neuroregeneration

Regional brain structural abnormality in ischemic stroke patients:a voxel-based morphometry study

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2016年第9期11卷 1424-1430页

作者： Ping Wu Yu-mei Zhou Fang Zeng Zheng-jie Li Lu Luo Yong-xin Li Wei Fan Li-hua Qiu Wei Qin Lin Chen Lin Bai Juan Nie San Zhang Yan Xiong Yu Bai Can-xin Yin Fan-rong Liang Acupuncture and Tuina School/Third Teaching Hospital Chengdu University of Traditional Chinese Medicine China Academy of Chinese Medical Sciences World Federation of Acupuncture-Moxibustion Societies Institute of Clinical Anatomy School of Basic Medical SciencesSouthern Medical University Radiology Department West China Hospital of Sichuan University Life Sciences Research Center School of Life Sciences and TechnologyXidian University

Our previous study used regional homogeneity analysis and found that activity in some brain areas of patients with ischemic stroke changed significantly. In the current study, we examined structural changes in these brain regions by taking structural magnetic resonance imaging scans of 11 ischemic stroke patients and 15 healthy participants, and analyzing the data using voxel-based morphometry. Compared with healthy participants, patients exhibited higher gray matter density in the left inferior occipital gyrus and right anterior white matter tract. In contrast, gray matter density in the right cerebellum, left precentral gyrus, right middle frontal gyrus, and left middle temporal gyrus was less in ischemic stroke patients. The changes of gray matter density in the middle frontal gyrus were negatively associated with the clin- ical rating scales of the Fugl-Meyer Motor Assessment （r = -0.609, P = 0.047） and the left middle temporal gyrus was negatively correlated with the clinical rating scales of the nervous functional deficiency scale （r = -0.737, P = 0.010）. Our findings call objectively identify the functional abnormality in some brain regions of ischemic stroke patients.

关键词： nerve regeneration ischemic stroke brain structure abnormality Junctional magnetic resonance imaging gray matter density voxel-based morphometry Fugl-Meyer Motor Assessment nervous fi^nctional deficiency scale functional deficiency neuroplasticity neuralreorganization neural regeneration

Brain structure in diving players on MR imaging studied with voxel-based morphometry

在线全文

学校读者我要写书评

暂无评论

Progress in Natural Science:Materials International 2009年第10期19卷 1397-1402页

作者： Gaoxia Wei a,Jing Luo a,Youfa Lib a Key Laboratory of Mental Health,Institute of Psychology,Chinese Academy of Sciences,Beijing 100101,China b National Key Laboratory of Cognitive Neurosciences and Learning,Beijing Normal University,Beijing 100875,China Key Laboratory of Mental Health Institute of Psychology Chinese Academy of Sciences Beijing 100101 China National Key Laboratory of Cognitive Neurosciences and Learning Beijing Normal University Beijing 100875 China

We adopted professional diving players as a typical subject pool to explore whether structural brain differences relative to motor skill acquisition exist between highly skilled athletes and *** on the voxel-based morphometric(VBM) technique,structural MRIs of the brains of 12 elite diving players with professional training were analyzed and compared with those of control subjects without any professional physical *** players showed significantly increased gray matter density in the thalamus and left pre-central gyrus than control ***,future researches are needed to prove the contribution of preposition and *** also suggests that athletes as the subject pool could form a new subject pool to explore plastic change induced by motor skill acquisition.

关键词： Cortical plasticity Motor skill acquisition voxel-based morphometry Diving players

Brain expansion in patients with type Ⅱ diabetes following insulin therapy:a preliminary study with longitudinal voxel-based morphometry

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Brain expansion in patients with type Ⅱ diabetes following ...

Multimodal abnormalities of brain structures in adolescents and young adults with major depressive disorder:An activation likelihood estimation meta-analysis

中国神经科学学会第十届全国学术会议

作者： Zhiye Chen Mengyu Liu Jie Sun Shengyu Yu Lin Ma Department of Radiology Chinese PLA General Hospital Department of Endocrinology Chinese PLA General Hospital Department of Neurology Chinese PLA General Hospital

Objective We performed a longitudinal analysis based on MR imaging to investigate the brain structural and perfusion changes caused by insulin therapy in patients with type Ⅱ *** High resolution three-dimensional T1-weighted fast spoiled gradient recalled echo images and flow-sensitive alternating inversion recovery（FAIR） images were obtained from 11 patients with type Ⅱ diabetes before and one year after initiation of insulin therapy and 11 normal *** volume changes were investigated by a longitudinal voxel-based morphometry,and perfusion changes were evaluated by FAIR imaging between baseline and follow-up *** Significant regional gray matter expansion located in bilateral frontal,parietal,and left occipital lobes,and regional white matter expansion was shown in left precentral subcortical white matter and right angular subcortical white matter after insulin therapy（P ＜ 0.05 with FDR correction）.Brain hyperperfusion was detected in bilateral frontal cortex,left occipital cortex,and right temporal cortex after insulin therapy（P ＜ 0.05）.Conclusions In patients with type Ⅱ diabetes,brain expansion and hyperperfusion were demonstrated one year after initiation of insulin therapy,and insulin therapy could contribute to the brain volume gainment in the patients with type Ⅱ diabetes.

关键词： type Ⅱ diabetes insulin voxel-based morphometry brain MRI

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2024年第7期14卷 1106-1117页

作者： Yan-Ping Shu Qin Zhang Yong-Zhe Hou Shuang Liang Zu-Li Zheng Jia-Lin Li Gang Wu Department of Psychiatry of Women and Children The Second People’s Hospital of Guizhou ProvinceGuiyang 550000Guizhou ProvinceChina Department of Radiology The Second People’s Hospital of Guizhou ProvinceGuiyang 550000Guizhou ProvinceChina Department of Radiology Guizhou Provincial People’s HospitalGuiyang 550000Guizhou ProvinceChina Medical Humanities College Guizhou Medical UniversityGuiyang 550000Guizhou ProvinceChina

BACKGROUND Major depressive disorder(MDD)in adolescents and young adults contributes significantly to global morbidity,with inconsistent findings on brain structural changes from structural magnetic resonance imaging *** likeli-hood estimation(ALE)offers a method to synthesize these diverse findings and identify consistent brain *** We performed a comprehensive literature search in PubMed,Web of Science,Embase,and Chinese National Knowledge Infrastructure databases for neuroi-maging studies on MDD among adolescents and young adults published up to November 19,*** independent researchers performed the study selection,quality assessment,and data *** ALE technique was employed to synthesize findings on localized brain function anomalies in MDD patients,which was supplemented by sensitivity *** Twenty-two studies comprising fourteen diffusion tensor imaging(DTI)studies and eight voxel-based morphome-try(VBM)studies,and involving 451 MDD patients and 465 healthy controls(HCs)for DTI and 664 MDD patients and 946 HCs for VBM,were ***-based ALE demonstrated significant reductions in fractional anisotropy(FA)values in the right caudate head,right insula,and right lentiform nucleus putamen in adolescents and young adults with MDD compared to HCs,with no regions exhibiting increased FA ***-based ALE did not demonstrate significant alterations in gray matter *** analyses highlighted consistent findings in the right caudate head(11 of 14 analyses),right insula(10 of 14 analyses),and right lentiform nucleus putamen(11 of 14 analyses).CONCLUSION Structural alterations in the right caudate head,right insula,and right lentiform nucleus putamen in young MDD patients may contribute to its recurrent nature,offering insights for targeted therapies.

关键词： Major depressive disorder Adolescent Young adults Neuroimaging Diffusion tensor imaging voxel-based morphometry Activation likelihood estimation Meta-analysis

针刺治疗偏头痛的效应机制研究:来自脑影像研究的证据(Ⅰ)

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Acupuncture-Moxibustion 2024年第1期34卷 16-23页

作者：刘国韵陈懿超曹子敏石安琪许璐凡李芷君杨泽秋闫超群王军北京中医药大学东直门医院针灸科北京100700

Objective:Magnetic resonance imaging(MRI)studies have demonstrated anatomical and functional alterations of brain regions in patients with migraine,and the efficacy of acupuncture for migraine could regulate these abnormal ***,its pathogenesis remains ambiguous,and inconsistent results have been *** purpose of this study was to explore abnormal structural and functional alterations in patients with migraine using voxel-based morphometry(VBM)analysis and a seed-based functional connectivity(FC)approach and to provide a basis for future ***:The study recruited 34 patients with migraine and 38 healthy controls who underwent structural and resting-state functional magnetic resonance imaging(fMRI).VBM was evaluated across the whole brain,and group differences in the gray matter(GM)were *** significantly altered GM volumes considered as the seeding area were further calculated for the FC of the whole *** correlation between structural or functional changes of the brain and clinical features was also ***:Patients with migraine manifested higher GM volumes in the left occipital lobe than healthy ***-based analyses demonstrated reduced FC between the left occipital lobe and right inferior frontal gyrus,extending to the anterior cingulate cortex(ACC)and right *** FC in the left ACC was positively correlated with visual analog scale(VAS)and self-rating anxiety scale(SAS).

关键词： Migraine Acupuncture Gray matter voxel-based morphometry Functional connectivity Magnetic resonance imaging

Abnormal volumetric brain morphometry and cerebral blood flow in adolescents with depression

在线全文

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2023年第6期13卷 386-396页

作者： Yu-Jia Fu Xiao Liu Xing-Yu Wang Xiao Li Lin-Qi Dai Wen-yu Ren Yong-Ming Zeng Zhen-Lin Li Ren-Qiang Yu Department of Radiology the First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Psychiatry the First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Radiology Chongqing HongRen Yi HospitalChongqing 408400China Department of Radiology West China HospitalChengdu 610041Sichuan ProvinceChina

BACKGROUND Prior research has demonstrated that the brains of adolescents with depression exhibit distinct structural ***,preliminary studies have documented the pathophysiological changes in certain brain regions,such as the cerebellum,highlighting a need for further research to support the current understanding of this *** To study brain changes in depressed *** This study enrolled 34 adolescents with depression and 34 age-,sex-,and education-level-matched healthy control(HC)*** and functional alterations were identified when comparing the brains of these two participant groups through voxel-based morphometry and cerebral blood flow(CBF)analysis,*** between identified brain alterations and the severity of depressive symptoms were explored through Pearson correlation *** The cerebellum,superior frontal gyrus,cingulate gyrus,pallidum,middle frontal gyrus,angular gyrus,thalamus,precentral gyrus,inferior temporal gyrus,superior temporal gyrus,inferior frontal gyrus,and supplementary motor areas of adolescents with depression showed an increase in brain volume compared to HC *** patients with depression further presented with a pronounced drop in CBF in the left pallidum(group=98,and peak t=-4.4324),together with increased CBF in the right percental gyrus(PerCG)(group=90,and peak t=4.5382).In addition,17-item Hamilton Depression Rating Scale scores were significantly correlated with the increased volume in the opercular portion of the left inferior frontal gyrus(r=-0.5231,P<0.01).CONCLUSION The right PerCG showed structural and CBF changes,indicating that research on this part of the brain could offer insight into the pathophysiological causes of impaired cognition.

关键词： voxel-based morphometry Cerebral blood flow Arterial spin labeling Adolescent Depression The right percental gyrus

Joint Multi-modal Parcellation of the Human Striatum:Functions and Clinical Relevance

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neuroscience Bulletin 2020年第10期36卷 1123-1136页

作者： Xiaojin Liu Simon B.Eickhoff Felix Hoffstaedter Sarah Genon Svenja Caspers Kathrin Reetz Imis Dogan Claudia R.Eickhoff Ji Chen Julian Caspers Niels Reuter Christian Mathys Andre Aleman Renaud Jardri Valentin Riedl Iris E.Sommer Kaustubh R.Patil Institute of Neuroscience and Medicine(INM-7 Brain and Behaviour)Research Centre JiilichJiilichGermany Institute of Systems Neuroscience Heinrich Heine University DusseldorfDusseldorfGermany Institute of Neuroscience and Medicine(INM-1) Research Centre Jiilich52428 JiilichGermany Institute for Anatomy I Medical FacultyHeinrich Heine University Dusseldorf40225 DusseldorfGermany Jiilich Aachen Research Alliance-BRAIN(JARA)Institute of Molecular Neuroscience and Neuroimaging Forschungszentrum JiilichRheinisch Westfallische Technische Hochschule(RWTH)Aachen University52074 AachenGermany Department of Neurology Rheinisch Westfallische Technische Hochschule(RWTH)Aachen University52074 AachenGermany Institute of Clinical Neuroscience and Medical Psychology Medical FacultyUniversity of Dusseldorf40225 DusseldorfGermany Department of Diagnostic and Interventional Radiology Medical FacultyUniversity of Dusseldorf40225 DusseldorfGermany Institute of Radiology and Neuroradiology Evangelisches KrankenhausUniversity of Oldenburg26129 OldenburgGermany Department of Neuroscience University Medical Center GroningenUniversity of Groningen9713 AV GroningenThe Netherlands SCALab(CNRS UMR9193)&CHU de LiUe Hopital FontanPole de Psychiatrie(CURE)Universite de Lille59037 LilleFrance Departments of Neuroradiology Nuclear Medicine and Neuroimaging CenterTechnische Universitat Miinchen80333 MunichGermany

The human striatum is essential for both lowand high-level functions and has been implicated in the pathophysiology of various prevalent disorders,including Parkinson's disease(PD)and schizophrenia(SCZ).It is known to consist of structurally and functionally divergent ***,previous parcellations are based on a single neuroimaging modality,leaving the extent of the multi-modal organization of the striatum ***,we investigated the organization of the striatum across three modalities—resting-state functional connectivity,probabilistic diffusion tractography,and structural covariance—to provide a holistic convergent view of its structure and *** found convergent clusters in the dorsal,dorsolateral,rostral,ventral,and caudal *** characterization revealed the anterior striatum to be mainly associated with cognitive and emotional functions,while the caudal striatum was related to action ***,significant structural atrophy in the rostral and ventral striatum was common to both PD and SCZ,but atrophy in the dorsolateral striatum was specifically attributable to *** study revealed a cross-modal convergent organization of the striatum,representing a fundamental topographical model that can be useful for investigating structural and functional variability in aging and in clinical conditions.

关键词： Striatum Multi-modal Connectivity-based parcellation Convergent clusters voxel-based morphometry Parkinson's disease Schizophrenia