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A new lignan derivative from the root of Ilex pubescens

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Chinese Chemical Letters 2008年第5期19卷 550-552页

作者： Yu Bo Zhou Jin Hui Wang xiang mei li Xian li School of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Shenyang 110016 China

One new compound, ilexlignan A （1）, was isolated from the root of llex pubescens. Its structure was elucidated by the combination of one- and two-dimensional NMR analysis, mass spectrometry, CD spectrum measurement ... 详细信息

关键词： llex pubescens llexlignan A lignan

维普期刊数据库

Derrisisoflavones H-K and One Isoflavan Derivative from Derris robusta

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Natural Products and Bioprospecting 2016年第2期6卷 111-116页

作者： Guo-Zhu Wei mei-Fen Mao xiang-mei li Fu-Cai Ren Fei Wang BioBioPha Co. Ltd.Kunming 650201People’s Republic of China

Four hitherto unknown prenylated isoflavonoids,named derrisisoflavones H-K(1-4)and one new isoflavan,namely 6-hydroxyisosativan(5),were isolated from the ethanol extract of Derris *** structures were elucidated on the basis of extensive spectroscopic *** our knowledge,derrisisoflavones J(3)and K(4)are the first examples of hydroxyethylated isoflavonoid.

关键词： Derris robusta Isoflavonoid Isoflavan Derrisisoflavone

Aristolane‑type Sesquiterpenoids from Nardostachys chinensis and Revised Structure of Aristolanhydride

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Natural Products and Bioprospecting 2019年第2期9卷 149-155页

作者： li-Xia Wang Xian-Jun Jiang xiang-mei li mei-Fen Mao Guo-Zhu Wei Fei Wang BioBioPha Co. Ltd.Kunming 650201People’s Republic of China Reference Substances Sub-center National Engineering Research Center for Modernization of Traditional Chinese MedicineKunming 650201People’s Republic of China

Four hitherto unknown aristolane-type sesquiterpenes,including one novel 8,9-secoaristolane,namely secoaristolenedioic acid(1),two aristolone derivatives,namely 1α,2β-dihydroxyaristolone(2),9-epidebilon(3),and one rare aristolane-chalcone hybrid,namely 3′-hydroxynardoaristolone A(4)were isolated from the ethanol extract of the roots and rhizomes of Nardostachys *** structures were elucidated on the basis of extensive spectroscopic *** addition,the structure of aristolanhydride,recently isolated from the same species,was corrected by reanalysis of the published NMR data.

关键词： Nardostachys chinensis Aristolane Secoaristolane Aristolane-chalcone hybrid Structural revision

Pterocarpadiols A–D, Rare 6a,11b-Dihydroxypterocarpans from Derris robusta

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Natural Products and Bioprospecting 2015年第6期5卷 287-291页

作者： xiang-mei li mei-Fen Mao Fu-Cai Ren Xian-Jun Jiang Ping Hai Fei Wang BioBioPha Co. Ltd.Kunming 650201People’s Republic of China

Four hitherto unknown 6a,11b-dihydroxypterocarpans,namely pterocarpadiols A–D(1–4),were isolated from the ethanol extract of the twigs and leaves of Derris *** structures were elucidated on the basis of extensive spectroscopic *** A–D are a kind of very rare 6a,11b-dihydroxypterocarpans,and their presence as markers may be helpful in chemotaxonomical classification.

关键词： Derris robusta 6a,11b-Dihydroxypterocarpan Pterocarpadiol

Prenylated Coumarins from Heracleum stenopterum,Peucedanum praeruptorum,Clausena lansium,and Murraya paniculata

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Natural Products and Bioprospecting 2016年第5期6卷 233-237页

作者： xiang-mei li Xian-Jun Jiang Ku Yang li-Xia Wang Shi-Zhen Wen Fei Wang BioBioPha Co. Ltd.Kunming 650201People’s Republic of China

Four hitherto unknown prenylated coumarins,namely 600-O-b-D-apiofuranosylapterin(1),40-O-isobutyroylpeguangxienin(2),6-(3-methyl-2-oxobutyroyl)-7-methoxycoumarin(3),and 6-hydroxycoumurrayin(4),were isolated from the ethanol extract of Heracleum stenopterum,Peucedanum praeruptorum,Clausena lansium,and Murraya paniculata,*** chemical structures were established on the basis of extensive spectroscopic ***pound 2 exhibited in vitro cytotoxic activity against five human cancer cell lines(HL-60,A-549,SMMC-7721,MCF-7,and SW-480)with IC50 values ranging from 15.9 to 23.2μM.

关键词： Heracleum stenopterum Peucedanum praeruptorum Clausena lansium Murraya paniculata Prenylated coumarin Cytotoxicity

New Iboga‑Type Indole Alkaloids from Tabernaemontana divaricata

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Natural Products and Bioprospecting 2019年第6期9卷 425-429页

作者： xiang-mei li Xian-Jun Jiang Guo-Zhu Wei li-Hua Ren li-Xia Wang Xue-lian Cheng Fei Wang BioBioPha Co. Ltd.Kunming 650201People’s Republic of China Reference Substance Branch National Engineering Research Center for Modernization of Traditional Chinese MedicineKunming 650201People’s Republic of China Department of Pharmacy The People’s Hospital of Fengjie CountyChongqing 404600People’s Republic of China

Two hitherto unknown iboga-type indole alkaloids,namely(3R)-7,19-di-epi-3-methoxytabernoxidine(1)and(3R,19R)-19-hydroxy-3-(2-oxopropyl)voacangine(2),together with eight known alkaloids(3-10),were isolated from the twigs and leaves of Tabernaemontana *** structures were established on the basis of spectroscopic data interpretation,single crystal X-ray diffraction analysis and circular dichroism spectrum.

关键词： Tabernaemontana divaricata Iboga-type indole alkaloid Single crystal X-ray diffraction

Polysubstituted Isoflavonoids from Spatholobus suberectus,Flemingia macrophylla,and Cudrania cochinchinensis

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Natural Products and Bioprospecting 2017年第2期7卷 201-206页

作者： li-Xia Wang Hai-Rong Zheng Fu-Cai Ren Tian-Gc Chen xiang-mei li Xian-Jun Jiang Fei Wang BioBioPha Co. Ltd.Kunming 650201People’s Republic of China

Four hitherto unknown polysubstituted isofiavonoids,including three isofiavans:7,4'-dihydroxy-8,2',3'-trimethoxyisofiavan(1),7,2',4'-trihydroxy-8,3'-dimethoxyisofiavan(2),and 7,2',4'-trihydroxy-5-methoxyisofiavan(3),and one prenylated isofiavone cudraisofiavone M(4)were isolated from the ethanol extracts of Spatholobus suberectus(for 1 and 2),Flemingia macrophylla(for 3),and Cudrania cochinchinensis(for 4),*** structures were established on the basis of extensive spectroscopic *** 1 and 4 exhibited weak cytotoxic activity against five human cancer cell lines(HL-60,A-549,SMMC-7721,MCF-7,and SW-480).

关键词： Spatholobus suberect us Flemingia macrophylla Cudrania cochinchinensis Isofiavan Isofiavone Cytotoxicity

Using Support Vector Machine to Predict Eco-environment Burden:A Case Study of Wuhan,Hubei Province,China

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Biomedical and Environmental Sciences 2008年第1期21卷 45-52页

作者： xiang-mei li JING-XUAN ZHOU SONG-HU YUAN XIN-PING ZHOU QIANG FU School of Environmental Science and Engineering Huazhong University of Science and Technology Wuhan 430074 Hubei China China Environmental Monitoring Center Beijing 100029 China

Objective The human socio-economic development depends on the planet＇s natural capital. Humans have had a considerable impact on the earth, such as resources depression and environment deterioration. The objective of this study was to assess the impact of socio-economic development on the ecological environment of Wuhan, Hubei Province, China, during the general planning period 2006-2020. Methods Support vector machine （SVM） model was constructed to simulate the process of eco-economic system of Wuhan. Socio-economic factors of urban total ecological footprint （TEF） were selected by partial least squares （PLS） and leave-one-out cross validation （LOOCV）. Historical data of socio-economic factors as inputs, and corresponding historical data of TEF as target outputs, were presented to identify and validate the SVM model. When predicted input data after 2005 were presented to trained model as generalization sets, TEFs of 2005, 2006,…, till 2020 were simulated as output in succession. Results Up to 2020, the district would have suffered an accumulative TEF of 28.374 million gha, which was over 1.5 times that of 2004 and nearly 3 times that of 1988. The per capita EF would be up to 3.019 gha in 2020. Contusions The simulation indicated that although the increase rate of GDP would be restricted in a lower level during the general planning period, urban ecological environment burden could not respond to the socio-economic circumstances promptly. SVM provides tools for dynamic assessment of regional eco-environment. However, there still exist limitations and disadvantages in the model. We believe that the next logical step in deriving better dynamic models of ecosystem is to integrate SVM and other algorithms or technologies.

关键词： Urban eco-environment Total ecological footprint Support vector machine Partial least square

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Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： Xiao xiang Feng Gao Yu-Gui Peng Peng Wu Zong-lin li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states