Prenylated Coumarins from Heracleum stenopterum,Peucedanum praeruptorum,Clausena lansium,and Murraya paniculata

作     者：Xiang-Mei Li Xian-Jun Jiang Ku Yang Li-Xia Wang Shi-Zhen Wen Fei Wang 

作者机构：BioBioPha Co.Ltd.Kunming 650201People’s Republic of China 

出 版 物：《Natural Products and Bioprospecting》 (应用天然产物（英文）)

年 卷 期：2016年第6卷第5期

页      面：233-237页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：National Development and Reform Commission  NDRC 

主　　题：Heracleum stenopterum Peucedanum praeruptorum Clausena lansium Murraya paniculata Prenylated coumarin Cytotoxicity 

摘      要：Four hitherto unknown prenylated coumarins,namely 600-O-b-D-apiofuranosylapterin(1),40-O-isobutyroylpeguangxienin(2),6-(3-methyl-2-oxobutyroyl)-7-methoxycoumarin(3),and 6-hydroxycoumurrayin(4),were isolated from the ethanol extract of Heracleum stenopterum,Peucedanum praeruptorum,Clausena lansium,and Murraya paniculata,*** chemical structures were established on the basis of extensive spectroscopic ***pound 2 exhibited in vitro cytotoxic activity against five human cancer cell lines(HL-60,A-549,SMMC-7721,MCF-7,and SW-480)with IC50 values ranging from 15.9 to 23.2μM.