Prenylated Coumarins from Heracleum stenopterum,Peucedanum praeruptorum,Clausena lansium,and Murraya paniculata
作者机构:BioBioPha Co.Ltd.Kunming 650201People’s Republic of China
出 版 物:《Natural Products and Bioprospecting》 (应用天然产物(英文))
年 卷 期:2016年第6卷第5期
页 面:233-237页
学科分类:0710[理学-生物学] 0832[工学-食品科学与工程(可授工学、农学学位)] 1007[医学-药学(可授医学、理学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 0703[理学-化学] 0901[农学-作物学] 100214[医学-肿瘤学] 0902[农学-园艺学] 10[医学]
基 金:National Development and Reform Commission NDRC
主 题:Heracleum stenopterum Peucedanum praeruptorum Clausena lansium Murraya paniculata Prenylated coumarin Cytotoxicity
摘 要:Four hitherto unknown prenylated coumarins,namely 600-O-b-D-apiofuranosylapterin(1),40-O-isobutyroylpeguangxienin(2),6-(3-methyl-2-oxobutyroyl)-7-methoxycoumarin(3),and 6-hydroxycoumurrayin(4),were isolated from the ethanol extract of Heracleum stenopterum,Peucedanum praeruptorum,Clausena lansium,and Murraya paniculata,*** chemical structures were established on the basis of extensive spectroscopic ***pound 2 exhibited in vitro cytotoxic activity against five human cancer cell lines(HL-60,A-549,SMMC-7721,MCF-7,and SW-480)with IC50 values ranging from 15.9 to 23.2μM.