Aristolane‑type Sesquiterpenoids from Nardostachys chinensis and Revised Structure of Aristolanhydride

作     者：Li-Xia Wang Xian-Jun Jiang Xiang-Mei Li Mei-Fen Mao Guo-Zhu Wei Fei Wang 

作者机构：BioBioPha Co.Ltd.Kunming 650201People’s Republic of China Reference Substances Sub-centerNational Engineering Research Center for Modernization of Traditional Chinese MedicineKunming 650201People’s Republic of China 

出 版 物：《Natural Products and Bioprospecting》 (应用天然产物（英文）)

年 卷 期：2019年第9卷第2期

页      面：149-155页

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 070303[理学-有机化学] 0710[理学-生物学] 0832[工学-食品科学与工程（可授工学、农学学位）] 1007[医学-药学(可授医学、理学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 0817[工学-化学工程与技术] 0703[理学-化学] 0901[农学-作物学] 0902[农学-园艺学] 

基　　金：supported by the“Large-scale Compound Library”project of National Development and Reform Commission of China 

主　　题：Nardostachys chinensis Aristolane Secoaristolane Aristolane-chalcone hybrid Structural revision 

摘      要：Four hitherto unknown aristolane-type sesquiterpenes,including one novel 8,9-secoaristolane,namely secoaristolenedioic acid(1),two aristolone derivatives,namely 1α,2β-dihydroxyaristolone(2),9-epidebilon(3),and one rare aristolane-chalcone hybrid,namely 3′-hydroxynardoaristolone A(4)were isolated from the ethanol extract of the roots and rhizomes of Nardostachys *** structures were elucidated on the basis of extensive spectroscopic *** addition,the structure of aristolanhydride,recently isolated from the same species,was corrected by reanalysis of the published NMR data.