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炭素技术 1989年第3期8卷 17-18页

作者： józef Gonsior Ewa Cebska teresa jeremicz Kazimierz Skoczkowski Piotr Stiebler Ginter Czerwicki 时雨

用Castner炉石墨化的电极性质及能量要求取决于温度的增长速率。实际上这一速率受被石墨化电极抗热应力的限制。基于石墨化期间炉芯尺寸的变化推荐出一个炉子功率供给的控制方法。

关键词：石墨化炉控制方法增长速率热应力膨胀仪石油焦单位压力电感传感器延伸率热裂纹

Global concerns related to water biology and security:The need for language and policies that safeguard living resources versus those that dilute scientific knowledge

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Water Biology and Security 2023年第4期2卷 136-146页

作者： Robert M.Hughes james R.Karr Robert L.Vadas Dominick A.DellaSala Marcos Callisto Maria joao Feio teresa Ferreira Neels Kleynhans Renata Ruaro Chris O.Yoder j.Hal Michael Amnis Opes Institute 2895 SE GlennCorvallisOR97333USA Department of Fisheries Wildlife&Conservation SciencesOregon State UniversityCorvallisOR97331USA School of Aquatic and Fishery Sciences University of WashingtonSeattleWA98915USA Karr Consulting 102 Galaxy View CourtSequimWA98382USA 2909 Boulevard Rd.SE OlympiaWA98501-3971USA Wild Heritage a Project of Earth Island Institute2150 Allston WayBerkeleyCA94704-1346USA Departamento de Genetica Ecologia e EvolucaoInstituto de Ciencias BiologicasUniversidade Federal de Minas GeraisAvenida Antonio Carlos 6627CEP 31270-901Belo HorizonteMGBrazil Associate Laboratory ARNET Marine and Environmental Sciences CentreDepartment of Life SciencesUniversity of CoimbraCoimbraPortugal Forest Research Centre&Associate Laboratory TERRA University of LisbonTapada da Ajuda1349-017LisbonPortugal Department of Water Affairs and Forestry(retired) 8th Avenue 771Wonderboom South0084PretoriaSouth Africa Graduate Program in Environmental Science and Technology Federal Technological University of Parana81280-340CuritibaPRBrazil Midwest Biodiversity Institute 4673 Northwest ParkwayHilliardOH43026USA Ecologists Without Borders OlympiaWAUSA

Increasingly,scientists and non-scientists,especially employees of government agencies,tend to use weak or equivocal language when making statements related to science policy and governmental *** use recent publications to provide examples of vague language versus examples of strong language when authors write about regulating anthropogenic pressures on natural *** language is common in agency reports,policy documents,and even scientific papers published by *** language limits success in regulating anthropogenic pressures on natural *** challenge must be recognized and countered as a driver of the condition of water and associated *** also list sources of vague wording,provide global examples of how ambiguous language and political influences have contributed to water resource degradation,discuss the recent history of science censorship,and offer possible solutions for more direct scientific *** found that:(1)equivocal language was especially common in concluding statements and not only by government employees;(2)authors discussed confusing language concerns in an agency publication;and(3)agency employees sometimes used active,strong *** drivers of weak language include:(1)holding on to old paradigms and resisting new knowledge;(2)scientific uncertainty;(3)institutional manuscript review policies;(4)employment and funding insecurity;and(5)avoiding the appearance of *** associated with euphemistic language included climate change,flow and physical habitat alteration,dams,agriculture,mining,forestry,and fisheries,as well as resistance towards monitoring,assessing,and reporting ecological *** for mitigating equivocal language involve employment protections and greater focus on scientific *** conclude that natural resource scientists should resist calls to employ imprecise ***,they should be strong advocates for prescriptive and protective natura

关键词： Corruption Ethics Science censoring Science policy Water resource degradation

杜克雷嗜血杆菌与人类树突状细胞和巨噬细胞体外的相互作用

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首都医科大学学报 2004年第2期25卷 193-197页

作者：徐婷婷 Hinda j.Ahmed Kristina Eriksson Karin Ahlman 杨永弘 teresa Lagergard 首都医科大学附属北京儿童医院儿科研究所瑞典哥德堡大学微生物和免疫教研室

为探讨抗原呈递细胞 (APCs)在软下疳发病机制中的作用 ,将树突状细胞 (DCs)和巨噬细胞 (MQs)与流感嗜血杆菌、杜克雷嗜血杆菌及其纯化抗原脂寡糖 (LOS)、细胞致死性肿胀毒素 (HdCDT)共育 ,测定它们的吞噬活性及6、2 4h时前炎症细胞因子T... 详细信息

为探讨抗原呈递细胞 (APCs)在软下疳发病机制中的作用 ,将树突状细胞 (DCs)和巨噬细胞 (MQs)与流感嗜血杆菌、杜克雷嗜血杆菌及其纯化抗原脂寡糖 (LOS)、细胞致死性肿胀毒素 (HdCDT)共育 ,测定它们的吞噬活性及6、2 4h时前炎症细胞因子TNF α、IL 1 β、IL 6、IL 8的分泌情况 ;将抗原作用后的细胞与自体CD4 + T淋巴细胞共育 ,测定T淋巴细胞增生及 48h细胞上清液中的细胞因子IFN γ、IL 4、IL 1 3的水平。结果 :约 6%～ 2 7%的DCs和 1 4%～ 2 6%的MQs吞噬杜克雷嗜血杆菌的不同菌株及无荚膜流感嗜血杆菌、大肠杆菌。杜克雷菌的不同菌株诱导DCs、MQs分泌大量的TNF α、IL 6、IL 8(P <0 .0 5 ) ;LOS诱导的前炎症细胞因子水平比细菌低 5 0 %～ 67% ;HdCDT不诱导任何前炎症细胞因子的产生。 2种细菌作用后的DCs、MQs能激活T淋巴细胞产生高水平IFN γ ,并诱导产生相似的T淋巴细胞增生 ,HdCDT无此作用。提示 :杜克雷菌能影响APCs活化T细胞的能力 ,并有助于Th1型反应。

关键词：杜克雷嗜血杆菌人类树突状细胞巨噬细胞发病机制吞噬试验

The 2<sup>nd</sup>Step by Step International Spinal Cord Repair—Combining research Step by Step into multi-pronged approaches for spinal cord repair

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journal of Biomedical Science and Engineering 2013年第7期6卷 21-32页

作者： Maria teresa Moreno-Flores Francois Ferón Victor Arvanian Armin Blesch Armin Curt David j. Fink Marina Mata Kinichi Nakashima Xavier Navarro Francisco javier Rodríguez Michal Schwartz Mikael Svensson Erik Sundstrom joan Romero Filip Lim Department of Biotechnology University Francisco de Vitoria Pozuelo de Alarcón Spain Department of Cell Biology Physiology and Immunology University Autonoma de Barcelona Barcelona Spain Department of Medicine University Hospital Balgrist Zurich Switzerland Department of Molecular Biology University Autónoma de Madrid Madrid Spain Department of Neurobiology Care Sciences and Society Karolinska Institute Stockholm Sweden Department of Neurobiology Weizmann Institute of Science Rehovot Israel Department of Neurology University of Michigan Ann Arbor USA Department of Stem Cell Biology and Medicine Kyushu University Fukuoka Japan Faculty of Medicine Aix Marseille University Marseille France National Paraplegics Hospital Toledo Spain Northport Veterans Affairs Medical Center Northport USA Spinal Cord Injury Center University Hospital Heidelberg Germany Step by Step Foundation Barcelona Spain

On April 26-27, 2013, the Step by Step Foundation hosted the Second International Spinal Cord Repair Meeting at the Fira Barcelona Convention Center in Hospitalet de Llobregat, Spain, highlighting some of the exciting research including clinical trials which show promise for treatments for this devastating disorder. This meeting brought together clinicians, clinical scientists and molecular biologists from more than 10 countries to evaluate current knowledge on clinical, cellular, and biomolecular aspects of spinal cord injury. A major goal of the conference in advancing the translation of research data to the clinic was to promote multi-pronged approaches for therapy of this complex problem.

关键词： Spinal Cord Injury Immunomodulation Glial Scar Nerve Grafts Neurotrophins Neural Stem Cells Electromagnetic Stimulation HSV-1 Vectors Cholecalciferol Vitamin D3 Wnt Proteins Neuroregeneration

The molecular interaction of ADAMTS-1 and fibulin-1 and its potential contribution to breast cancer biology

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journal of Cancer Metastasis and Treatment 2019年第5期4卷 1-15页

作者： Yamina Mohamedi Tania Fontanil teresa Cobo jose A.Vega juan L.Cobo Olivia García-Suárez juan Cobo Santiago Cal Alvaro j.Obaya Departamento de Bioquímica y Biología Molecular Universidad de OviedoOviedo 33006AsturiasSpain Instituto Universitario de Oncología IUOPAUniversidad de OviedoOviedo 33006AsturiasSpain Departamento de Investigación Clínica OrdonezOviedo 33012AsturiasSpain Instituto Asturiano de Odontología Universidad de OviedoOviedo 33006AsturiasSpain Departamento de Cirugía y Especialidades Médico-Quirúrgicas Universidad de OviedoOviedo 33006AsturiasSpain Departamento de Morfología y Biología Celular Facultad de MedicinaUniversidad de OviedoOviedo 33006AsturiasSpain Facultad de Ciencias de la Salud Universidad Autónoma de ChileProvidenciaSantiago 7500912Chile Servicio de Cirugía Maxilofacial Hospital Universitario Central de Asturias(HUCA)Oviedo 33011AsturiasSpain Departamento de Biología Funcional Area de FisiologíaUniversidad de OviedoOviedo 33006AsturiasSpain

Aim: Fibulins and ADAMTSs are two families of extracellular matrix proteins implicated in key functional and pathological processes. The fact that the fibulin-1 and ADAMTS-1 proteins interact raises new questions about the roles of these extracellular matrix proteins in modulating tumor progression. Herein, we described the functional implications of the interaction between fibulin-1 and ADAMTS-1 on the behavior of breast cancer cell lines. Methods: Fibulin-1 and ADAMTS-1 were exogenously expressed in MCF-7 and MDA-MB-231 cell lines to assay the effect of their interaction in cellular properties. Results: ADAMTS-1 expression exacerbates tumor effects in terms of proliferation, invasion and mammosphere formation. In contrast, the simultaneous expression of ADAMTS-1 and fibulin-1 impairs these effects. The analysis of the expression of both proteins in human breast cancer tissue arrays provides new insights into the complex roles of fibulin-1 and ADAMTS-1 in this type of tumor. ;Conclusion: Our results suggests that the interaction between ADAMTS-1 and fibulin-1 induces a pronounced anti-tumoral effect.

关键词： ADAMTS-1 fibulin-1 cell migration cell proliferation breast cancer MCF-7 MDA-MB-231

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激发内驱力

Prediction of genetic value for sweet cherry fruit maturity among environments using a 6K SNP array

作者： (美)特蕾莎·M·阿马比尔(teresa M. Amabile) (美)史蒂文·j·克雷默(Steven j. Kramer)

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Horticulture Research 2019年第1期6卷 1623-1637页

作者： Craig M.Hardner Ben j.Hayes Satish Kumar Stijn Vanderzande Lichun Cai julia Piaskowski joséQuero-Garcia joséAntonio Campoy teresa Barreneche Daniela Giovannini Alessandro Liverani Gérard Charlot Miguel Villamil-Castro Nnadozie Oraguzie Cameron P.Peace University of Queensland Queensland Alliance for Agriculture and Food InnovationBrisbaneQLD 4072Australia The New Zealand Institute for Plant and Food Research Limited Hawke’s Bay Research CentreHastings 4130New Zealand Department of Horticulture Washington State UniversityPullmanWA 99164USA Department of Horticulture Michigan State UniversityEast LansingMI 48824USA UMR 1332 BFP INRAUniversity of Bordeaux33140 Nouvelle-AquitaineFrance Council for Agricultural Research and Economics(CREA) Fruit Unit of ForlìVia la Canapona1 bis47121 Emilia-RomagnaItaly Centre Technique Interprofessionnel des Fruits et Légumes(CTIFL) 751 Chemin de Balandran30127 BellegardeFrance Department of Horticulture Washington State UniversityIrrigated Agriculture Research and Extension Center24106N Bunn RoadProsserWA 99350USA

The timing of fruit maturity is an important trait in sweet cherry production and *** variation for phenology of fruit maturity in sweet cherry appears to be under strong genetic control,but that control might be complicated by phenotypic instability across *** such genotype-by-environment interaction(G×E)is a common phenomenon in crop plants,knowledge about it is lacking for fruit maturity timing and other sweet cherry *** this study,1673 genome-wide SNP markers were used to estimate genomic relationships among 597 weakly pedigree-connected individuals evaluated over two seasons at three locations in Europe and one location in the USA,thus sampling eight‘environments’.The combined dataset enabled a single meta-analysis to investigate the environmental stability of genomic *** disequilibrium among marker loci declined rapidly with physical distance,and ordination of the relationship matrix suggested no strong structure among *** most parsimonious G×E model allowed heterogeneous genetic variance and pairwise covariances among ***-sense genomic heritability was very high(0.60–0.83),as was accuracy of predicted breeding values(>0.62).Average correlation of additive effects among environments was high(0.96)and breeding values were highly correlated across *** indicated that genomic models can be used in cherry to accurately predict date of fruit maturity for untested individuals in new *** G×E for this trait indicated that phenotypes of individuals will be stable across similar *** analyses for other sweet cherry traits,for which multiple years of data are commonly available among breeders and cultivar testers,would be informative for predicting performance of elite selections and cultivars in new environments.

关键词： maturity environments breeding

Adaptive optics as a tool for controlling the optical signals reaching the retina

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Annals of Eye Science 2017年第1期 331-333页

作者： joséj.Esteve-Taboada teresa Ferrer-Blasco Robert Montés-Micó Department of Optics and Optometry and Vision Sciences University of ValenciaValenciaSpain

The use of adaptive optics systems in ophthalmic research studies has increased in the last years thanks to the development of more accurate *** optics was first introduced in Astronomy for the correction of the effects produced by the turbulences of the Earth’s atmosphere when observing astronomical objects(1,2).Sophisticated deformable mirrors controlled by computers can correct in real time atmospheric disturbances,allowing for much finer details on the images of distance *** optics technology makes it possible to correct many of the aberrations with which the wavefront,i.e.,the geometric envelope of all the rays of light that emerged at the same time of the observed object,*** optics allows for obtaining sharper images,and thus,with better spatial resolution.

关键词： optics details correction

justification of public investment initiatives on water transfer systems as an instrument for water balances in Spain: the case of the júcar-Vinalopó water transfer system

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Rat cardiomyocyte H9c2(2-1)-based sulforhodamine B assay as a promising in vitro method to assess the biological component of effluent toxicity

Agricultural Sciences（农业科学） 2011年第4期

作者： Martin Sevilla teresa Torregrosa

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journal of Environmental Sciences 2020年第10期32卷 163-170页

作者： Elsa T Rodrigues Susana F Nascimento Maria joao Moreno Paulo j Oliveira Miguel A Pardal University of Coimbra Centre for Functional EcologyDepartment of Life SciencesCalcada Martim de FreitasCoimbra 3000-456Portugal University of Coimbra Coimbra Chemistry CenterDepartment of ChemistryCoimbra 3004-535Portugal Centre for Neuroscience and Cell Biology Uniuersity of CoimbraUC BiotechBiocant ParkCantanhede 3060-197Portugal

The treatment of wastewaters is crucial to maintain the ecological status of receiving waters,and thereby guarantee the protection of aquatic life and human *** quality evaluation is conventionally based on physicochemical parameters,but increasing attention has been paid to integrate physicochemical and biological ***,the regulatory use of fish in biological testing methods has been subject to various ethical and cost concerns,and in vitro cell-based assays have thus become an important topic of ***,the present study intends:(a) to evaluate the efficiency of two different sample pre-concentration techniques (lyophilisation and solid phase extraction) to assess the toxicity of municipal effluents on rat cardiomyoblast H9c2(2-1) cells,and (b) maximizing the use of the effluent sample collected,to estimate the environmental condition of the receiving *** gathered results demonstrate that the H9c2(2-1) sulforhodamine B-based assay is an appropriate in vitro method to assess biological effluent toxicity,and the best results were attained by lyophilising the sample as *** to its response,the H9c2(2-1) cell line might be a possible alternative in vitro model for fish lethal testing to assess the toxicity of municipal *** physicochemical status of the sample suggests a high potential for eutrophication,and iron exceeded the permissible level for wastewater discharge,possibly due to the addition of ferric chloride for wastewater *** general,the levels of carbamazepine and sulfamethoxazole are higher than those reported for other countries,and both surpassed the aquatic protective values for long-term exposure.

关键词： Municipal wastewater treatment plant effluent Lyophilisation Solid phase extraction Cell-based assays H9c2(2-1)cell line SRB assay