检索结果-南通市图书馆

Bioactives and extracts affect the physico-chemical properties of concentrated whey protein isolate dispersions

Food Production, Processing and Nutrition 2022年第1期4卷 25-40页

作者： Mackenzie M.hansen richard W.hartel Yrjöh.Roos Food Technology School of Food and Nutritional SciencesUniversity College CorkCorkIreland Department of Food Science College of Agricultural and Life SciencesUniversity of WisconsinOffice A11Babcock Hall1605 Linden DriveMadisonWI53706USA

Non-covalent complexation interactions are known to occur between bioactive compounds and proteins. While formulating with these components can have positive outcomes such as stabilization of colors and actives, it can also result in changes to the structures and physical properties of proteins, affecting product functionality and sensory attributes. Previous experiments reported measurable changes in the physico-chemical properties of whey protein isolate (WPI) dispersions upon formulation with Aronia berry extract, ascribing changes to protein-polyphenol (PP) interactions in the systems. Pure gallotannin, beet extract, and cranberry extract, providing a diverse variety structures and sizes, were selected for further experimentation and comparison with the effects of Aronia extract. Concentrated dispersions with varying WPI:sucrose ratios, formulated with several bioactives contents from multiple different sources were analyzed to identify the effects of different bioactives on physico-chemical properties of dispersions. Dispersions formulated with cranberry extract demonstrated the largest increases in surface tensions, viscosities, and particle sizes, while those formulated with beet extract were the least affected by the presence of bioactives, suggesting that different bioactives and extracts had varying propensities for complexation interactions with WPI, despite their relatively low levels of addition (0, 0.5, and 1%).

关键词： Whey protein Concentrated dispersions Polyphenols Extracts Physico-chemical properties

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nonalcoholic fatty liver disease is associated with benign gastrointestinal disorders

引用

World Journal of Gastroenterology 2013年第45期19卷 8301-8311页

作者： Srinevas K Reddy Min Zhan h richard Alexander Samer S El-Kamary Department of Surgery University of Maryland School of Medicine BaltimoreMD 21201 United States Department of Epidemiology and Public health University of Maryland School of Medicine Baltimore MD 21201United States Departments of Pediatrics Epidemiology and Public Health University of Maryland School of MedicineBaltimore MD 21201 United States

AIM:To explore associations between nonalcoholic fatty liver disease(NAFLD)and benign gastrointestinal and pancreato-biliary ***:Patient demographics,diagnoses,and hospital outcomes from the 2010 Nationwide Inpatient Sample were *** liver diseases were identified using International Classification of Diseases,the 9thRevision,Clinical Modification *** with NAFLD were compared to those with other chronic liver diseases for the endpoints of total hospital charges,disease severity,and hospital *** stepwise logistic regression analyses to assess for the independent association of demographic,comorbidity,and diagnosis variables with the event of NAFLD(vs other chronic liver diseases)were also ***:Of 7800441 discharge records,32347(0.4%)and 271049(3.5%)included diagnoses of NAFLD and other chronic liver diseases,*** patients were younger(average 52.3 years vs55.3 years),more often female(58.8%vs 41.6%),less often black(9.6%vs 18.6%),and were from higher income areas(23.7%vs 17.7%)compared to counterparts with other chronic liver diseases(all Phypertension(56.9%vs 47.6%),morbid obesity(36.9%vs 8.0%),dyslipidemia(37.9%vs 15.6%),and the metabolic syndrome(28.75%vs 8.8%)were all more common among NAFLD patients(all Phe average total hospital charge($39607 vs$51665),disease severity scores,and intra-hospital mortality(0.9%vs6.0%)were lower among NALFD patients compared to those with other chronic liver diseases(all Ph other chronic liver diseases,NAFLD was significantly associated with diverticular disorders[OR=4.26(3.89-4.67)],inflammatory bowel diseases[OR=3.64(3.10-4.28)],gallstone related diseases[OR=3.59(3.40-3.79)],and benign pancreatitis[OR=2.95(2.79-3.12)]on multivariable logistic regression(all Phen the latter disorders were the principal diagnoses on hospital *** relationships were observ

关键词： Nationwide inpatient sample Nonalcoholic fatty liver disease Chronic liver disease Diverticular disease Pancreatitis Gallstones Inflammatory bowel disease

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of Aronia polyphenols on the physico-chemical properties of whey,soy,and pea protein isolate dispersions

引用

Food Production, Processing and Nutrition 2021年第1期3卷 391-405页

作者： Mackenzie M.hansen richard W.hartel Yrjö h.Roos Food Technology School of Food and Nutritional SciencesUniversity College CorkCorkIreland Department of Food Science College of Agricultural and Life SciencesUniversity of WisconsinOffice A11Babcock Hall1605 Linden DriveMadisonWI 53706USA

Bioactive compounds including polyphenols(PP)have been observed to naturally form non-covalent complexation interactions with proteins under mild ph and temperature conditions,affecting protein structures and ***,addition of Aronia berry PP to liquid dispersions containing whey protein isolate(WPI)and sucrose was found to alter characteristics including viscosity,surface tension,and particle sizes,with changes being attributed to protein-PP *** this study we aimed to investigate whether Aronia PP would interact with soy and pea protein isolates(SPI and PPI,respectively)to a similar extent as with WPI in liquid protein-sucrose-PP *** hypothesized that formulations containing PPI(comprised of larger proteins)and hydrolyzed SPI(containing more carboxyl groups)may exhibit increased viscosities and decreased aggregate sizes due to enhanced protein-PP *** liquid dispersions of varied ratios of protein to sucrose contents,containing different protein isolates(WPI,SPI,and PPI),and varied Aronia PP concentrations were formulated,and physical properties were evaluated to elucidate the effects of PP *** addition altered physical characteristics differently depending on the protein isolate used,with changes attributed to protein-PP *** and PPI appeared to have higher propensities for PP interactions and exhibited more extensive shifts in physical properties than WPI *** findings may be useful for practical applications such as formulating products containing fruit and proteins to obtain desirable sensory attributes.

关键词： Whey protein Soy protein Pea protein Polyphenols Concentrated dispersions Physico-chemical properties

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impacts of climate change on mangrove ecosystems:a region by region overview

引用

Ecosystem health and Sustainability 2016年第4期2卷 18-43页

作者： Raymond D.Ward Daniel A.Friess richard h.Day richard A.MacKenzie Aquatic Research Centre University of BrightonCockcroft BuildingMoulsecoombBrightonBN24GJUK Department of Geography National University of Singapore1 Arts LinkSingapore117570Singapore US Geological Survey 700 Cajundome BoulevardLafayetteLouisiana 70506 USA Institute of Pacific Islands Forestry Pacific Southwest Research Station60 Nowelo StreetHiloHawaii 96720 USA

Inter-related and spatially variable climate change factors including sea level rise,increased storminess,altered precipitation regime and increasing temperature are impacting mangroves at re-gional *** review highlights extreme regional variation in climate change threats and impacts,and how these factors impact the structure of mangrove communities,their biodiversity and geo-morphological *** these factors interplay to determine spatially variable resiliency to climate change impacts,and because mangroves are varied in type and geographical location,these systems are good models for understanding such interactions at different *** level rise is likely to in-fluence mangroves in all regions although local impacts are likely to be more *** in the frequency and intensity of storminess are likely to have a greater impact on N and Central America,Asia,Australia,and East Africa than West Africa and *** review also highlights the nu-merous geographical knowledge gaps of climate change impacts,with some regions particularly understudied(e.g.,Africa and the Middle East).While there has been a recent drive to address these knowledge gaps especially in South America and Asia,further research is required to allow research-ers to tease apart the processes that influence both vulnerability and resilience to climate change.A more globally representative view of mangroves would allow us to better understand the importance of mangrove type and landscape setting in determining system resiliency to future climate change.

关键词： coastal wetlands cyclone resiliency sea level rise Special Feature:Wetlands and Global Cimate and Land-Use Change storms surface elevation change vulnerability

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Expansion of GARP-Expressing CD4^(+)CD25^(-)FoxP3^(+)T Cells and SATB1Association with Activation and Coagulation in Immune Compromised hIV-1-Infected Individuals in South Africa

引用

Virologica Sinica 2021年第5期36卷 1133-1143页

作者： Eman Teer Danzil E.Joseph Leanne Dominick richard h.Glashoff M.Faadiel Essop Centre for Cardio-Metabolic Research in Africa(CARMA) Department of Physiological SciencesStellenbosch UniversityStellenbosch 7600South Africa Division of Medical Microbiology and Immunology Department of PathologyStellenbosch University and NHLSCape Town 7505South Africa

Although antiretroviral treatment lowers the burden of human immunodeficiency virus(hIV)-related disease,it does not always result in immunological *** manifests as persistent chronic inflammation,immune activation or exhaustion that can promote the onset of *** the exact function of regulatory T(Treg)cells in hIV remains unclear,this cross-sectional study investigated three expression markers(Forkhead box protein P3[FOXP3],glycoprotein A repetitions predominant[GARP],special AT-rich sequence binding protein 1[SATB1])and compared their expansion between CD4^(+)CD25^(-)and CD4^(+)CD25^(++)T ***-matched study subjects were recruited(Western Cape,South Africa)and sub-divided:hIV-negative subjects(n=12),hIV-positive na(i|")ve treated(n=22),hIV-positive treated based on CD4 count cells/μL(CD4>500 and CD4hIV-treated based on viral load(VL)copies/mL(VL1000)(n=34).Markers of immune activation(CD38)and coagulation(CD142)on T cells(CD8)were assessed by flow cytometry together with FOXP3,GARP and SATB1 expression on CD4^(+)CD25^(-)and CD4^(+)CD25^(++)T *** levels of interleukin-10(IL-10;anti-inflammatory marker),IL-6(inflammatory marker)and D-dimer(coagulation marker)were *** study revealed three major findings in immuno-compromised patients with virological failure(CD41000):(1)the expansion of the unconventional Treg cell subset(CD4^(+)CD25^(-)FOXP3^(+))is linked with disease progression markers;(2)increased GARP expression in the CD4^(+)CD25^(-)and CD4^(+)CD25^(++)subsets;and(3)the identification of a strong link between CD4^(+)CD25^(-)SATB1+cells and markers of immune activation(CD8^(+)CD38^(+))and coagulation(CD8^(+)CD142^(+)and D-dimer).

关键词： human immunodeficiency virus(hIV) Regulatory T cells(Treg) Immune activation Progression markers Glycoprotein A repetitions predominant(GARP) Forkhead box protein P3(FOXP3)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Future directions for screening and treatment in congenital hearing loss

引用

Precision Clinical Medicine 2020年第3期3卷 175-186页

作者： Ryan K.Thorpe richard J.h.Smith Molecular Otolaryngology and Renal Research Laboratories Carver College of MedicineUniversity of Iowa375 Newton RdIowa CityIA 52242USA Department of Otolaryngology–head and Neck Surgery University of Iowa200 Hawkins DrIowa CityIA 52242USA The Interdisciplinary Graduate Program in Genetics University of Iowa375 Newton RdIowa CityIA 52242USA Iowa Institute of human Genetics University of Iowa375 Newton RdIowa CityIA 52242USA

hearing loss is the most common neurosensory *** results froma variety of heritable and acquired causes and is linked to multiple deleterious effects on a child’s development that can be ameliorated by prompt identification and individualized *** hearing loss in newborns is challenging,especially in mild or progressive cases,and its management requires a multidisciplinary team of healthcare providers comprising audiologists,pediatricians,otolaryngologists,and genetic *** physiologic newborn hearing screening has resulted in earlier diagnosis of hearing loss than ever before,a growing body of knowledge supports the concurrent implementation of genetic and cytomegalovirus testing to offset the limitations inherent to a singular screening *** this review,we discuss the contemporary role of screening for hearing loss in newborns as well as future directions in its diagnosis and treatment.

关键词： genetic hearing loss deafness cytomegalovirus newborn screening precision medicine

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Three global conditions for biodiversity conservation and sustainable use: an implementation framework

引用

National Science Review 2019年第6期6卷 1080-1082页

作者： harvey Locke Erle C.ellis Oscar Venter richard Schuster Keping Ma Xiaoli Shen Stephen Woodley Naomi Kingston Nina Bhola Bernardo B.N.Strassburg Axel Paulsch Brooke Williams James E.M.Watson Beyond the Aichi Targets Task Force IUCN World Commission on Protected Areas and Yellowstone to Yukon Conservation Initiative Department of Geography and Environmental Systems University of Maryland Natural Resources and Environmental Studies Institute University of Northern British Columbia Department of Biology Carleton University State Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of Sciences IUCN World Commission on Protected Areas UN Environment Programme World Conservation Monitoring Centre UNEP-WCMC

’Nature and its vital contributions to people, which together embody biodiversity and ecosystem functions and services, are deteriorating worldwide’ [1].The United Nations Convention on Biological Diversity(CBD) is intended to ensure conservation of biodiversity,its wise use, and sharing of benefits from use of genetic resources. Through

关键词： Three global conditions for biodiversity conservation and sustainable use an implementation framework

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Mammalian cell cultures as models for Mycobacterium tuberculosis-human immunodeficiency virus(hIV) interaction studies:A review

引用

Asian Pacific Journal of Tropical Medicine 2016年第9期9卷 809-816页

作者： Walter Chingwaru richard h.Glashoff Jerneja Vidmar Petrina Kapewangolo Samantha L.Sampson DST/NRF Centre of Excellence for Biomedical Tuberculosis Research/SAMRC Centre for Tuberculosis Research Division of Molecular Biology and Human GeneticsFaculty of Medicine and Health SciencesStellenbosch University Institute Ceres/Zavod Ceres Department of Biological Sciences Faculty of ScienceBindura University Science Education Division of Medical Virology Faculty of Medicine and Health SciencesStellenbosch University Department of Plastic and Reconstructive Surgery University Medical Centre Maribor Department of Chemistry and Biochemistry Faculty of ScienceUniversity of Namibia

Mycobacterium tuberculosis(MTB) and human immunodeficiency virus(hIV) co-infections have remained a major public health concern worldwide,particularly in Southern *** our understanding of the molecular interactions between the pathogens has remained poor,primarily due to lack of suitable preclinical models for such *** reviewed the use,this far,of mammalian cell culture models in hIV-MTB interaction *** have described the use of primary human cell cultures,including monocyte-derived macrophage(MDM) fractions of peripheral blood mononuclear cell(PBMC),alveolar macrophages(AM),cell lines such as the monocyte-derived macrophage cell line(U937),T lymphocyte cell lines(CEMx174,ESAT-6-specific CD4+ T-cells) and an alveolar epithelial cell line(A549) and special models such as stem cells,three dimensional(3D) or organoid cell models [including a blood-brain barrier(BBB) cell model] in hIV-MTB interaction *** use of cell cultures from other mammals,including:mouse cell lines [macrophage cell lines RAW 264.7 and J774.2,fibroblast cell lines(NIh 3T3,C3 h clones),embryonic fibroblast cell lines and T-lymphoma cell lines(***,TIMI.4 and R1.1)]; rat(T cells:Rat2,RGE,XC and hh16,and alveolar cells:NR8383) and primary guinea pigs derived AMs,in hIV-MTB studies is also *** the spectrum of the models available,cell cultures offer great potential for host-hIV-MTB interactions studies.

关键词： hIV Mycobacterium tuberculosis Cell lines Primary cell models Co-infection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impact of bolus volume on small intestinal intra-luminal impedance in healthy subjects

引用

World Journal of Gastroenterology 2010年第17期16卷 2151-2157页

作者： Nam Q Nguyen Laura K Bryant Carly M Burgstad Robert J Fraser Daniel Sifrim richard h holloway Department of Gastroenterology & hepatology Royal Adelaide HospitalAdelaide 5000Australia Investigation and Procedures Unit Repatriation General HospitalDaw Park 5041Australia Department of Medicine Centre for Gastroen-terological ResearchK.U.LeuvenLeuven 3000Belgium

AIM: To assess the impact of bolus volume on the characteristics of small intestinal (SI) impedance ***: Concurrent SI manometry-impedance measurements were performed on 12 healthy volunteers to assess the pattern of proximal jejunal fluid bolus movement over a 14 *** subject was given 34 boluses of normal saline (volume from 1 to 30 mL) via the feeding tube placed immediately above the proximal margin of the studied segment.A bolus-induced impedance event occurred if there was > 12% impedance drop from baseline,over ≥ 3 consecutive segments within 10 s of bolus injection.A minor or major imped-ance event was defined as a duration of impedance drop he minimum volume required for a detectable SI impedance event was 2 mL.A direct linear relationship between the SI bolus volume and the occurrence of impedance events was noted until SI bolus volume reached 10 mL,a volume which always produced an impedance flow *** was a moderate correlation between the bolus volume and the duration of impedance drop (r = 0.63,P he number of propagated channels (r = 0.50,P high volume boluses were associated with more major impedance events (≥ 10 mL boluses = 63%,3 mL boluses = 17%,and had an impact on the type and length of propagation of SI impedance events and a threshold of 2 mL is required to produce an event.

关键词： Bolus volume health Impedance Luminal flow Small intestine

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Production Process and Properties of a highly Porous Al Alloy Made Using NaCl Droplets as a Space holder

引用

Acta Metallurgica Sinica(English Letters) 2015年第8期28卷 1034-1040页

作者： Manuela Covaciu Andrew richard Kennedy Faculty of Engineering University of Nottingham Faculty of Material Science and Engineering Universitatea Tehnica din Cluj-Napoca School of Engineering Pontificia Universidad Católica de Chile

Porous Al structures have been made using a porogen leaching method but with additional novel steps. In this way, Al-0.25Cu-0.6Si-1.0Mg alloys with interconnected, open cells have been made, with high levels of porosity（up to 89%）. The use of 4 to 5 mm diameter sodium chloride droplets combined with interspersion of the metal powder and droplets in the die and dissolution of the salt before sintering was found to enable easier interspersion of the two components, resulting in good connectivity of the beads via the formation of ‘‘windows＇＇ between the pores, and rapid elimination of salt from the structure. Porous Al with densities in the range of 0.28–0.86 g/cm3 exhibited compressive yield strengths in the range of 0.14 to 7.5 MPa, with no difference being observed between the samples made by this route and by more conventional dissolution of the salt after sintering. These novel steps widen the possibility for porous metal manufacture to other materials, not limited by the need to have a sintering temperature below that for the melting point of salt.

关键词： Aluminium alloy Sodium chloride Porous metal

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：