Future directions for screening and treatment in congenital hearing loss
作者机构：Molecular Otolaryngology and Renal Research LaboratoriesCarver College of MedicineUniversity of Iowa375 Newton RdIowa CityIA 52242USA Department of Otolaryngology–Head and Neck SurgeryUniversity of Iowa200 Hawkins DrIowa CityIA 52242USA The Interdisciplinary Graduate Program in GeneticsUniversity of Iowa375 Newton RdIowa CityIA 52242USA Iowa Institute of Human GeneticsUniversity of Iowa375 Newton RdIowa CityIA 52242USA
出 版 物：《Precision Clinical Medicine》 (精准临床医学（英文）)
年 卷 期：2020年第3卷第3期
页 面：175-186页
学科分类：1002[医学-临床医学] 100213[医学-耳鼻咽喉科学] 10[医学]
基 金：This project was supported by NIH-NIDCD(Grants No.R01 DC002842,DC012049,and DC017955)(RJHS) NIH-NIDCD(Grant No.5T32DC000040)(RKT)
主 题：genetic hearing loss deafness cytomegalovirus newborn screening precision medicine
摘 要：Hearing loss is the most common neurosensory *** results froma variety of heritable and acquired causes and is linked to multiple deleterious effects on a child’s development that can be ameliorated by prompt identification and individualized *** hearing loss in newborns is challenging,especially in mild or progressive cases,and its management requires a multidisciplinary team of healthcare providers comprising audiologists,pediatricians,otolaryngologists,and genetic *** physiologic newborn hearing screening has resulted in earlier diagnosis of hearing loss than ever before,a growing body of knowledge supports the concurrent implementation of genetic and cytomegalovirus testing to offset the limitations inherent to a singular screening *** this review,we discuss the contemporary role of screening for hearing loss in newborns as well as future directions in its diagnosis and treatment.
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