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Associations of soybean products intake with blood pressure changes and hypertension incidence: the China-PAR project

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Journal of Geriatric Cardiology 2020年第7期17卷 384-392页

作者： Jia-liu WEI xin-Yan WANG Fang-Chao liU Ji-Chun CHEN Jie CAO jian-xin li Dong-Sheng HU Chong SHEN Fang-Hong LU Ying-xin ZHAO jian-Feng HUANG Xiang-Feng LU Key Laboratory of Cardiovascular Epidemiology Chinese Academy of Medical SciencesBeijingChina Department of Epidemiology Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Prevention Medicine Shenzhen University School of MedicineShenzhenChina Department of Epidemiology and Health Statistics College of Public HealthZhengzhou UniversityZhengzhouChina Department of Epidemiology and Biostatistics School of Public HealthNanjing Medical UniversityNanjingChina Cardio-Cerebrovascular Control and Research Center Institute of Basic MedicineShandong First Medical UniversityJinanShandongChina

Background The relationships between dietary intake of soybean products and incident hypertension were still *** study aimed to illustrate the associations between intake of soybean products with risks of incident hypertension and longitudinal changes of blood pressure in a prospective cohort *** We included 67,499 general Chinese adults from the Project of Prediction for Atherosclerosis Cardiovascular Disease Risk in China(China-PAR).Information about soybean products consumption was collected by standardized questionnaires,and study participants were categorized into the ideal(≥125 g/day)or non-ideal(lized linear models were used to examine the relationships between soybean products consumption and blood pressure *** During a median follow-up of 7.4 years,compared with participants who consumedlic and diastolic blood pressure levels were 1.05(0.71-1.39)mmHg and 0.44(0.22-0.66)mmHg lower among participants in the ideal group than those in the non-ideal *** Our study showed that intake of soybean products might reduce the long-term blood pressure levels and hypertension incidence among Chinese population,which has important public health implications for primary prevention of hypertension.

关键词： Blood pressure changes Chinese population Cohort study Hypertension Soybean products

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Influence of dissolved oxygen content on oxidative stability of linked polymer solution

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Petroleum Science 2009年第4期6卷 421-425页

作者： Zhao-xia Dong Mei-qin lin jian xin Ming-yuan li China Univ Petr Enhanced Oil Recovery Res Ctr Beijing 102249 Peoples R China

The influence of dissolved oxygen content on the oxidative stability of a linked polymer solution (LPS) was studied by micro-filtration, dynamic light scattering and viscosity measurements. The results showed that at the same temperature, the degree of the oxidative degradation of the LPS increased and the rapidity of the oxidative degradation was accelerated with the increase of the dissolved oxygen content. Consequently, the size of linked polymer coils (LPCs) of the LPS became small, and the plugging capability of the LPS decreased. At a fixed content of dissolved oxygen, with increasing degradation temperature, almost the same results were observed, namely, an increased degree of oxidative degradation, accelerated rapidity of the oxidative degradation and decreased plugging capacity, with decreased oxidative stability of LPS. At 90 °C, in the presence of oxygen, LPS lost its plugging capability after having been degraded for a period of time. But at 40 °C, LPS with low dissolved oxygen content could be stable for a long time. The decreased plugging ability of LPS after oxidative degradation is mainly caused by the decreased size and number of the LPCs due to the breaking of hydrolyzed polyacrylamide (HPAM) molecule segments and the structural changing of HPAM molecules.

关键词： linked polymer solution HPAM content of dissolved oxygen degradation stability

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Preparation and Characterization of Phosphorus Pentafluoride Gas for lithium Ion Battery Electrolyte Salt

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Chemical Research in Chinese Universities 2009年第6期25卷 791-795页

作者： liU jian-wen li xin-hai WANG Zhi-xing GUO Hua-jun HU Qi-yang School of Metallurgical Science and Engineering Central South University Changsha 410083 P. R. China

A novel preparation method of phosphorus pentafluoride（PF5） is introduced in details in the article. Phosphorus pentafluoride is mainly used to synthesize lithium ion battery electrolyte salt. In the experiment mesneproduct- hexafluorophosphoric acid（HPF6） was firstly prepared-from phosphorus pentoxide（P2O5） and anhydrous hydrogen fluoride（HF）, according to the chemical stoichiometrics, the optimum amount of excess HF used was about 60% and the optimum reaction time was 4 h; then HPF6 was dehydrated by oleum with an excess amount of 35%-- 40% which was heated for 40--50 min at 150 ℃; thus HPF6 was decomposed to a mixture of gases containing PF5; impurity gases were removed through condensation in the presence of cooling water at 0 ℃, then PF5 of high purity was eventually prepared. The production was characterized by inffared（IR） spectrometry and gas chromatography-mass spectroscopy-selected ion monitoring（GC-MS-SIM）. Eventual results indicate that PF5 prepared by the novel method has a high target purity and a low amount of impurity and water.

关键词： Hexafluorophosphoric acid Phosphorus pentafluoride Preparation lnfrared spectrum Gas chromatogra- phy-mass spectroscopy-selected ion monitoring

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Biocatalyzed cross-coupling of sinomenine and 1,2-dihydroxybenzene by Coriolus unicolor

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Chinese Chemical Letters 2012年第3期23卷 321-324页

作者： Zhang Shuang Deng Dan Zhao Yi Hu jian xin li Kun Zou Jun Zhi Wang Hubei Key Laboratory of Natural Products Research and Development College of Chemistry and Life ScienceChina Three Gorges UniversityYichang 443002China Institute of Chemical Biology and Drug Innovation School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210093China School of Chemistry and Chemical Engineering Nanjing UniversityNanjing 210093China State Key Laboratory of Materials-Oriented Chemical Engineering College of Biotechnology and Pharmaceutical EngineeringNanjing University of TechnologyNanjing 210009China

Sinomenine is a clinically available drug for the treatment of rheumatoid arthritis（RA）.In a continuous research aiming at discovery of sinomenine derivates with better bioactivity,a cross-coupling reaction of sinomenine and 1,2-dihydroxybenzene catalyzed by a fungus Coriolus unicolor afforded an unique C-C cross-coupled compound 2,together with（S）-disinomenine and （R）-*** structure of 2 was elucidated by MS and NMR *** 2 was further assayed for the inhibitory activity on IL-6 overproduction in SW982 cells and exhibited a much more potent activity on IL-6（96%inhibition） compared with those of（S）-disinomenine and sinomenine（17%and 12%inhibition,respectively）.

关键词： Sinomenine 1 2-Dihydroxybenzene Cross-coupling Coriolus unicolor IL-6

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Design of quaternary ammonium type-ionic liquids as desiccants for an air-conditioning system

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Green Chemical Engineering 2020年第2期1卷 109-116页

作者： Sho Maekawa Ryo Matsumoto Kenta Ito Toshiki Nokami jian-xin li Hiroshi Nakayama Toshiyuki Itoh Department of Chemistry and Biotechnology Graduate School of EngineeringTottori UniversityJapan Center for Research on Green Sustainable Chemistry Tottori University4-101 Koyama-minamiTottori680-8552Japan State Key Lab of Analytical Chemistry for life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjingPR China Chubu Electric Power Co.Inc.Research and Development Division Advanced Research and Innovation Center20-1 Kitasekiyama Ohtaka-choMidori-kuNagoya459-8522Japan Toyota Physical and Chemical Research Institute 41-1 YokomichiNagakute CityAichi480-1192Japan

The liquid desiccant air-conditioning system allows reducing energy consumption compared to the conventional compressor-type air *** order to develop desiccant materials for air conditioners,we have investigated the dehumidification capability of quaternary ammonium Ionic liquids(ILs)and the equilibrium water vapor pressure of aqueous solutions of these ammonium *** the seven tested types of ILs,2-hydroxyN,N,N-trimethylethan-1-aminium dimethylphosphate([Ch][DMPO4])displayed the best dehumidification capability and the lowest equilibrium water vapor ***,the 80%aqueous solution of[Ch][DMPO4]exhibited a less corrosive effect on four types of metals,i.e.,steel(hot dip zinc-aluminum alloy plated steel),copper(C1100P),aluminum(A5052),and stainless steel(SUS:SUS304).It should be noted that this[Ch][DMPO4]is not only non-toxic but also exhibits a stable nature;the aqueous solution produced no odor after storing for over 1 year under ambient conditions.

关键词： Dehumidification liquid desiccant Choline type ionic liquid Air-conditioner system

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Associations of tea consumption with blood pressure progression and hypertension incidence

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Journal of Geriatric Cardiology 2021年第8期18卷 645-653页

作者： Xiao-Ge NIU Can CAI Fang-Chao liU jian-xin li Ke-Yong HUANG Xue-li YANG Jie CAO Shu-Feng CHEN Hong-Fan li Chong SHEN Ying-xin ZHAO Dong-Sheng HU Shu-Jun GU jian-Feng HUANG Xiang-Feng LU Dong-Feng GU Department of Epidemiology State Key Laboratory of Cardiovascular DiseaseFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Tianjin Key Laboratory of Environment Nutrition and Public HealthDepartment of Occupational and Environmental HealthSchool of Public HealthTianjin Medical UniversityTianjinChina Department of Epidemiology and Biostatistics School of Public HealthNanjing Medical UniversityNanjingChina Cardio-Cerebrovascular Control and Research Center Institute of Basic MedicineShandong First Medical University(Shandong Academy of Medical Sciences)JinanChina Department of Epidemiology and Health Statistics College of Public HealthZhengzhou UniversityHenanChina Department of Biostatistics and Epidemiology School of Public HealthShenzhen University Health Science CentreShenzhenChina Changshu Center for Disease Control and Prevention JiangsuChina School of Medicine Southern University of Science and TechnologyShenzhenChina

BACKGROUND Association between tea consumption and incident hypertension remains *** study conducted to examine the health effects of tea consumption on blood pressure progression and hypertension *** A population-based cohort of 38,913 Chinese participants without hypertension at baseline were included in the current *** on tea consumption was collected through standardized *** of tea consump-tion with blood pressure progression and incident hypertension were analyzed using logistic regression models and Cox propor-tional hazards regression models,*** During a median follow-up of 5.9 years,17,657 individuals had experienced progression to a higher blood pressure stage and 5,935 individuals had developed *** multivariate analyses,habitual tea drinkers(≥3 times/week for at least six months)had a 17%lower risk for blood pressure progression[odds ratio(OR)=0.83,95%CI:0.79-0.88]and a 14%de-creased risk for incident hypertension[hazard ratio(HR)=0.86,95%CI:0.80-0.91]compared with non-habitual tea ***-dividuals in different baseline blood pressure groups could obtain similar benefit from habitual tea *** terms of tea con-sumption amount,an inverse,linear dose-response relation between monthly consumption of tea leaves and risk of blood pres-sure progression was observed,while the risk of incident hypertension did not reduce further after consuming around 100 g of tea leaves per *** Our study demonstrated that habitual tea consumption could provide preventive effect against blood pres-sure progression and hypertension incidence.

关键词： hypertension progression consuming

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Phase-controlled van der Waals growth of wafer-scale 2D MoTe_(2) layers for integrated high-sensitivity broadband infrared photodetection

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light(Science & Applications) 2023年第1期12卷 77-88页

作者： Di Wu Chenguang Guo Longhui Zeng Xiaoyan Ren Zhifeng Shi Long Wen Qin Chen Meng Zhang xin jian li Chong-xin Shan jiansheng Jie School of Physics and Microelectronics Key Laboratory of Material Physics Ministry of EducationZhengzhou UniversityZhengzhouHenan 450052China Department of Electrical and Computer Engineering University of California San DiegoLa JollaCA 92093USA Institute of Nanophotonics Jinan UniversityGuangzhouGuangdong 511443China Institute of Functional Nano and Soft Materials(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials and DevicesSoochow UniversitySuzhouJiangsu 215123China

Being capable of sensing broadband infrared(IR)light is vitally important for wide-ranging applications from fundamental science to industrial ***-dimensional(2D)topological semimetals are being extensively explored for broadband IR detection due to their gapless electronic structure and the linear energy dispersion ***,the low charge separation efficiency,high noise level,and on-chip integration difficulty of these semimetals significantly hinder their further technological ***,we demonstrate a facile thermal-assisted tellurization route for the van der Waals(vdW)growth of wafer-scale phase-controlled 2D MoTe_(2)***,the type-ⅡWeyl semimetal 1T'-MoTe_(2)features a unique orthorhombic lattice structure with a broken inversion symmetry,which ensures efficient carrier transportation and thus reduces the carrier *** characteristic is a key merit for the well-designed 1T'-MoTe_(2)/Si vertical Schottky junction photodetector to achieve excellent performance with an ultrabroadband detection range of up to 10.6μm and a large room temperature specific detectivity of over 108 Jones in the mid-infrared(MIR)***,the large-area synthesis of 2D MoTe_(2)layers enables the demonstration of high-resolution uncooled MIR imaging capability by using an integrated device *** work provides a new approach to assembling uncooled IR photodetectors based on 2D materials.

关键词： hinder enable difficulty

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Synthesis, structure and spectroscopic properties oforganophosphoryl polyoxotungstates of Formula α-[R_2PW_9O_(34)]^(5-)(R=C_6H_5P(S), C_6H_(11)P(O))

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Chinese Chemical Letters 1999年第11期10卷 971-972页

作者： Zhen Gang SUN jian xin li Qun liU Jing Fu liU(Department. of Chemistry, Northeast Normal University, Changchun 130024) NE Normal Univ Dept Chem Changchun 130024 Peoples R China

Tetrabutylammonium salt of organophosphoryl derivatives of trivacant tungstophosphateof formula α -[R_2PW_9O_34]~5-(R=C_6H_5P(S), C_6H_11P(O)) have been prepared, purified andcharacterized by elemental analysis, IR, ~31P and ~183W NMR. According to spectroscopicobservations and chemical analysis, the hybrid anion consists of an α-[PW_9O_34]~9- framework onwhich are grafted two equivalent organophosphoryl groups through P-O-W bridges, and the IRspectral data show that these new species still retain the keggin structure.

关键词： Polyoxometalates organophosphorus complex.

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Beneficial effects of moderate to vigorous physical activity on cardiovascular disease among Chinese adults

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Journal of Geriatric Cardiology 2020年第2期17卷 85-95页

作者： Qiong liU Fang-Chao liU Ke-Yong HUANG jian-xin li Xue-li YANG xin-Yan WANG Ji-Chun CHEN Xiao-Qing liU Jie CAO Chong SHEN ling YU Fang-Hong LU Xian-Ping WU lian-Cheng ZHAO Ying li Dong-Sheng HU Xiang-Feng LU jian-Feng HUANG Dong-Feng GU Key Laboratory of Cardiovascular Epidemiology Chinese Academy of Medical SciencesBeijingChina Department of Epidemiology Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Division of Epidemiology Guangdong Provincial People’s Hospital and Cardiovascular InstituteGuangzhouChina Department of Epidemiology and Biostatistics School of Public HealthNanjing Medical UniversityNanjingChina Department of Cardiology Fujian Provincial HospitalFuzhouChina Cardio-Cerebrovascular Control and Research Center Institute of Basic MedicineShandong Academy of Medical SciencesJinanChina Sichuan Center for Disease Control and Prevention ChengduChina Department of Prevention Medicine Shenzhen University School of MedicineShenzhenChina

Background In China,lack of evidence remains a significant challenge for the national initiative to promote physical activity(PA).We aimed to quantify the beneficial effects of meeting or maintaining the recommended PA level[150 minutes per week(min/wk)of moderate PA or 75 min/wk of vigorous PA or an equivalent combination]on incident cardiovascular disease(CVD)among Chinese *** We included 100,560 participants without history of CVD from three cohorts in the Prediction for Atherosclerotic Cardiovascular Disease Risk in China(China-PAR)*** proportional hazards models were used to estimate hazard ratios(HRs)and 95%confidence intervals(CIs)for CVD events and its subtypes,including stroke,coronary heart disease,heart failure,and CVD *** During a median follow-up of 7.3 years(range:6–15 years),777,163 person-years and 4693 incident CVD events were *** with participants who were inactive at baseline,the multivariable adjusted HR(95%CI)of developing CVD was 0.74(0.69–0.79)for those who met recommended moderate to vigorous physical activity(MVPA)level at ***,the risk of CVD incidence was reduced with increment of MVPA(Ptrendline and follow-up,those keeping active over the period of follow-up had a substantial lower risk of incident CVD with the HR(95%CI)of 0.57(0.43–0.77).Conclusions The findings demonstrated that meeting and maintaining the recommended MVPA level could reduce the cardiovascular *** adoption of the PA recommendations would have considerable health impacts to the Chinese population.

关键词： Cardiovascular disease China Cohort study Physical activity

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lifestyle improvement and the reduced risk of cardiovascular disease:the China-PAR project

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Journal of Geriatric Cardiology 2023年第11期20卷 779-787页

作者： Ying-Ying jianG Fang-Chao liU Chong SHEN jian-xin li Ke-Yong HUANG Xue-li YANG Ji-Chun CHEN Xiao-Qing liU Jie CAO Shu-Feng CHEN ling YU Ying-xin ZHAO Xian-Ping WU lian-Cheng ZHAO Ying li Dong-Sheng HU jian-Feng HUANG Xiang-Feng LU Dong-Feng GU Department of Epidemiology Center for Global HealthSchool of Public HealthNanjing Medical UniversityNanjingChina Department of Epidemiology Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Key Laboratory of Cardiovascular Epidemiology Chinese Academy of Medical SciencesBeijingChina Research Units of Cohort Study on Cardiovascular Diseases and Cancers Chinese Academy of Medical SciencesBeijingChina Tianjin Key Laboratory of Environment Nutrition and Public HealthDepartment of Occupational and Environmental HealthSchool of Public HealthTianjin Medical UniversityTianjinChina Division of Epidemiology Guangdong Provincial People's Hospital and Cardiovascular InstituteGuangzhouChina Department of Cardiology Fujian Provincial HospitalFuzhouChina Cardio-Cerebrovascular Control and Research Center Institute of Basic MedicineShandong Academy of Medical SciencesJinanChina Sichuan Center for Disease Control and Prevention ChengduChina Department of Epidemiology and Health Statistics College of Public HealthZhengzhou UniversityZhengzhouChina Department of Epidemiology and Health Statistics School of Public HealthShenzhen University Health Science CenterShenzhenChina School of Medicine Southern University of Science and TechnologyShenzhenChina

BACKGROUND The benefits of healthy lifestyles are well recognized. However, the extent to which improving unhealthy lifestyles reduces cardiovascular disease(CVD) risk needs to be discussed. We evaluated the impact of lifestyle improvement on CVD incidence using data from the China-PAR project(Prediction for Atherosclerotic Cardiovascular Disease Risk in China).METHODS A total of 12,588 participants free of CVD were followed up for three visits after the baseline examination. Changes in four lifestyle factors(LFs)(smoking, diet, physical activity, and alcohol consumption) were assessed through questionnaires from the baseline to the first follow-up visit. Cox proportional hazard models were used to estimate hazard ratios(HRs) and corresponding 95% confidence intervals(CIs). The risk advancement periods(RAPs: the age difference between exposed and unexposed participants reaching the same incident CVD risk) and population-attributable risk percentage(PAR%) were also *** A total of 909 incident CVD cases occurred over a median follow-up of 11.14 years. Compared with maintaining 0-1healthy LFs, maintaining 3–4 healthy LFs was associated with a 40% risk reduction of incident CVD(HR = 0.60, 95% CI: 0.45–0.79)and delayed CVD risk by 6.31 years(RAP:-6.31 [-9.92,-2.70] years). The PAR% of maintaining 3–4 unhealthy LFs was 22.0%compared to maintaining 0-1 unhealthy LFs. Besides, compared with maintaining two healthy LFs, improving healthy LFs from 2to 3–4 was associated with a 23% lower risk of CVD(HR = 0.77, 95% CI: 0.60–0.98).CONCLUSIONS Long-term sustenance of healthy lifestyles or improving unhealthy lifestyles can reduce and delay CVD risk.

关键词： hazard maintaining alcohol

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