Associations of soybean products intake with blood pressure changes and hypertension incidence: the China-PAR project

作     者：Jia-Liu WEI Xin-Yan WANG Fang-Chao LIU Ji-Chun CHEN Jie CAO Jian-Xin LI Dong-Sheng HU Chong SHEN Fang-Hong LU Ying-Xin ZHAO Jian-Feng HUANG Xiang-Feng LU Jia-Liu WEI;Xin-Yan WANG;Fang-Chao LIU;Ji-Chun CHEN;Jie CAO;Jian-Xin LI;Dong-Sheng HU;Chong SHEN;Fang-Hong LU;Ying-Xin ZHAO;Jian-Feng HUANG;Xiang-Feng LU

作者机构：Key Laboratory of Cardiovascular EpidemiologyChinese Academy of Medical SciencesBeijingChina Department of EpidemiologyFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Prevention MedicineShenzhen University School of MedicineShenzhenChina Department of Epidemiology and Health StatisticsCollege of Public HealthZhengzhou UniversityZhengzhouChina Department of Epidemiology and BiostatisticsSchool of Public HealthNanjing Medical UniversityNanjingChina Cardio-Cerebrovascular Control and Research CenterInstitute of Basic MedicineShandong First Medical UniversityJinanShandongChina 

出 版 物：《Journal of Geriatric Cardiology》 (老年心脏病学杂志（英文版）)

年 卷 期：2020年第17卷第7期

页      面：384-392页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(2017-I2M-1-004,2019-I2M-2-003) National Key Research&Development Program of China(2017YFC0211700) National Natural Science Foundation of China(91843302).The authors declared no conflicts of interest 

主　　题：Blood pressure changes Chinese population Cohort study Hypertension Soybean products 

摘      要：Background The relationships between dietary intake of soybean products and incident hypertension were still *** study aimed to illustrate the associations between intake of soybean products with risks of incident hypertension and longitudinal changes of blood pressure in a prospective cohort *** We included 67,499 general Chinese adults from the Project of Prediction for Atherosclerosis Cardiovascular Disease Risk in China(China-PAR).Information about soybean products consumption was collected by standardized questionnaires,and study participants were categorized into the ideal(≥125 g/day)or non-ideal(125 g/day)*** ratios(HRs)and corresponding 95%confidence intervals(95%CIs)for incident hypertension were calculated using Cox proportional hazard *** participants with repeated measures of blood pressure,generalized linear models were used to examine the relationships between soybean products consumption and blood pressure *** During a median follow-up of 7.4 years,compared with participants who consumed125 g of soybean products per day,multivariable adjusted HR for those in the ideal group was 0.73(0.67-0.80).This inverse association remained robust across most subgroups while significant interactions were tested between soybean products intake and age,sex,urbanization and geographic region(P values for interaction0.05).The mean systolic and diastolic blood pressure levels were 1.05(0.71-1.39)mmHg and 0.44(0.22-0.66)mmHg lower among participants in the ideal group than those in the non-ideal *** Our study showed that intake of soybean products might reduce the long-term blood pressure levels and hypertension incidence among Chinese population,which has important public health implications for primary prevention of hypertension.