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Electron 2024年第1期2卷 68-94页

作者： Xiaoyang Yue Lei Cheng Eszter Baráth Rajenahally v.jagadeesh Quanjun Xiang State key Laboratory of Electronic Thin Film and Integrated Devices School of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengduChina'2Synergies in CatalysisCatalysis for Sustainable SynthesesLeibniz‐Institut für Katalyse e.V.RostockGermany'3Jiangsu Key Laboratory of New Power BatteriesJiangsu Collaborative Innovation Center of Biomedical Functional MaterialsSchool of Chemistry and Materials ScienceNanjing Normal UniversityNanjingChina

The catalytic coordinate is essentially the evolving frontier orbital interaction while feeding with catalytic materials and adsorbates under proper reaction *** heterogeneous catalytic reaction mechanism involves the initial adsorption and activation of reactants,subsequent intermediate transformation,final target product desorption,and regeneration of catalytic *** these catalytic processes,interaction modulations in terms of orbital hybridization/coupling allow an intrinsic control on both thermodynamics and *** charge transfer and redistribution,orbital splitting and rearrangement with specific orientation,and spin change and crossover pose a formidable challenge on mechanism elucidation;it is hard to precisely correlate the apparent activity and selectivity,let alone rational modulations on ***,deciphering the orbital couplings inside a catalytic round is highly desirable and the dependent descriptor further provides in-depth insights into catalyst design at the molecule orbital *** review hopes to provide a comprehensive understanding on orbital hybridizations,modulations,and correlated descriptors in heterogeneous catalysis.

关键词： catalysis catalyst design and prediction descriptors interactions orbital hybridization

Surface integrity of ball burnished bioresorbable magnesium alloy

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Advances in Manufacturing 2023年第2期11卷 342-362页

作者： G.v.jagadeesh Srinivasu Gangi Setti Department of Mechanical Engineering National Institute of Technology RaipurChhattisgarh492010India

Magnesium alloys are potential biodegradable and biocompatible implant materials because of their excellent biological properties. Recently, interest in these alloys as a promising alternative for temporary orthopedic implants has grown owing to their desirable biological, mechanical, and physical properties. However, the application of magnesium alloys is hindered by their rapid degradation and low corrosion resistance in physiological fluids, leading to the failure of implants. Thus, the current challenge is to enhance the corrosion resistance and control the degradation rate of magnesium under physiological conditions. The rapid degradation of magnesium alloys can be controlled by improving their surface integrity, such as surface roughness and microhardness. The present study aims to improve the surface integrity of the Mg Ze41A alloy by the ball burnishing technique. The surface roughness improved by 94.90% from 0.941 μm to 0.048 μm with a burnishing force of 50 N, burnishing speed of 1 300 r/min, burnishing feed of 130 mm/min, and three passes. Similarly, the microhardness improved by 50.62% from 75.2 Hv to 113.27 Hv with a burnishing force of 60 N, burnishing speed of 1 100 r/min, burnishing feed of 100 mm/min, and five passes. The variations in microhardness, which were observed up to 400 μm beneath the surface, exhibited a linear nature. These variations may be attributed to the movement of dislocations, formation of new dislocations, nanocrystal structures, metastable phases and subgrains, and lattice distortion or grain refinement. The surface features obtained from optical images demonstrated the fundamental mechanisms involved in the ball burnishing process. The concept of burnishing maps and zones will assist in the design of the ball burnishing parameters of a material with an equivalent yield strength of 140 MPa. The significant improvement in the surface integrity of the Mg Ze41A alloy by the ball burnishing technique is expected to improve its func

关键词： Magnesium alloy Bioresorbable Orthopedic implants Surface integrity Ball burnishing

mpaired regulatory T cell function in autoimmune Jiseases： are microRNAs the culprits？

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Cellular & Molecular Immunology 2016年第2期13卷 135-137页

作者： varun k Sharma Srini v.k.veri jagadeesh Bayry Institut National de la Sante et de la Recherche Medicale Unit6 1138 Paris France Centre de Recherche des Cordeliers Equipe - Imm unopathology and therapeutic immunointervention Paris France International Associated Laboratory IMPACT Institut National de la Sante et de la Recherche Medicale Paris France and Indian Council of Medical Research India National Institute of Immuno- haematology Mumbai India Sorbonne Universites UPMC Univ Paris 06 UMR S 1138 Paris France Universite Paris Descartes Sorbonne Paris Cite UMR S 1138 Paris France

MicroRNAs （miRNAs） are evolu- tionarily conserved small non-coding RNA sequences, approximately 22 nucleotides in length, that act as negative regulators of target genes via binding to the 3＇-untranslated region of... 详细信息

关键词： microRNA 调节性T细胞免疫功能 miRNAs RNA序列 mRNA 非翻译区非编码

Experimental investigation and prediction of tribological behavior of unidirectional short castor oil fiber reinforced epoxy composites

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Friction 2021年第2期9卷 250-272页

作者： Rajesh EGALA G v jagadeesh Srinivasu Gangi SETTI Department of Mechanical Engineering National Institute of Technology RaipurChhattisgarh 492010India Department of Mechanical Engineering Gudlavalleru Engineering CollegeGudlavalleruAndhra Pradesh 521356India

The present study aims at introducing a newly developed natural fiber called castor oil fiber,termed ricinus communis,as a possible reinforcement in *** short castor oil fiber reinforced epoxy resin composites of different fiber lengths with 40%volume fraction were fabricated using hand layup *** sliding wear tests were performed on a pin-on-disc tribometer based on full factorial design of experiments(DoE)at four fiber lengths(5,10,15,and 20 mm),three normal loads(15,30,and 45 N),and three sliding distances(1,000,2,000,and 3,000 m).The effect of individual parameters on the amount of wear,interfacial temperature,and coefficient of friction was studied using analysis of variance(ANOvA).The composite with 5 mm fiber length provided the best tribological properties than 10,15,and 20 mm fiber length *** worn surfaces were analyzed under scanning electron ***,the tribological behavior of the composites was predicted using regression,artificial neural network(ANN)-single hidden layer,and ANN-multi hidden layer *** confirmatory test results show the reliability of predicted *** with multi hidden layers are found to predict the tribological performance accurately and then followed by ANN with single hidden layer and regression model.

关键词： natural fiber castor oil fiber epoxy composite full factorial design of experiments(DoE) analysis of variance(ANOvA) prediction regression artificial neural network(ANN)

Induction of human dendritic cell maturation by naïve and memory B-cell subsets requires different activation stimuli

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Cellular & Molecular Immunology 2018年第12期15卷 1074-1076页

作者： Mohan S.Maddur Srini v.k.veri jagadeesh Bayry Institut National de la Santéet de la Recherche Médicale Paris F-75006France Centre de Recherche des Cordeliers EquipeImmunopathologie et Immunointervention ThérapeutiqueParis F-75006France Sorbonne Université Paris F-75006France UniversitéParis Descartes Sorbonne Paris CitéParis F-75006France Present address:Pfizer Inc.Pearl RiverNew YorkNYUSA

Dendritic cells(DCs)are the master regulators of the immune response and engage in constant cross-talk with other immune cells to initiate an appropriate immune *** outcome of cross-talk with various immune cells towards DC functions has been shown to be dependent on the particular subset of cells and their activation *** we show that for human B cells to induce maturation of DCs with an enhanced T-cell stimulatory capacity,B-cell receptor(BCR)signaling is sufficient for memory B-cells,whereas additional CD40 signaling is required for naïve B cells to induce complete activation of DCs.

关键词： activation immune maturation

Deep Learning Based Intrusion Detection in Cloud Services for Resilience Management

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Computers, Materials & Continua 2022年第6期71卷 5117-5133页

作者： S.Sreenivasa Chakravarthi R.jagadeesh kannan v.Anantha Natarajan Xiao-Zhi Gao CSE Center for Intelligent ComputingSree Vidyanikethan Engineering College&School of Computer Science and EngineeringVITChennaiTamilnadu600127India School of Computer Science and Engineering VITChennaiTamilnadu600127India CSE Center for Intelligent ComputingSree Vidyanikethan Engineering CollegeTirupati517102India School of Computing University of Eastern FinlandKuopio02130EspooFinland

In the global scenario one of the important goals for sustainable development in industrial field is innovate new technology,and invest in building *** the developed and developing countries focus on building resilient infrastructure and promote sustainable developments by fostering *** this juncture the cloud computing has become an important information and communication technologies model influencing sustainable development of the industries in the developing *** part of the innovations happening in the industrial sector,a new concept termed as‘smart manufacturing’has emerged,which employs the benefits of emerging technologies like internet of things and cloud *** services deliver an on-demand access to computing,storage,and infrastructural platforms for the industrial users through *** the recent era of information technology the number of business and individual users of cloud services have been increased and larger volumes of data is being processed and stored in *** a consequence,the data breaches in the cloud services are also increasing day by *** to various security vulnerabilities in the cloud architecture;as a result the cloud environment has become *** restore the normal behavior of the cloud,detect the deviations,and achieve higher resilience,anomaly detection becomes *** deep learning architectures-based anomaly detection mechanisms uses various monitoring metrics characterize the normal behavior of cloud services and identify the abnormal *** paper focuses on designing an intelligent deep learning based approach for detecting cloud anomalies in real time to make it more *** deep learning models are trained using features extracted from the system level and network level performance metrics observed in the Transfer Control Protocol(TCP)traces of the *** experimental results of the proposed approach demonstrate a superior performance in terms

关键词： Anomaly detection network flow data deep learning migration auto-encoder support vector machine

Anti-IgE IgG autoantibodies isolated from therapeutic normal IgG intravenous immunoglobulin induce basophil activation

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Cellular & Molecular Immunology 2020年第4期17卷 426-429页

作者： Caroline Galeotti Anupama karnam Jordan D.Dimitrov Alain Chevailler Srini v.k.veri jagadeesh Bayry Institut National de la Santéet de la Recherche Médicale/Centre de Recherche des Cordeliers Equipe-Immunopathologie et Immunointervention ThérapeutiqueSorbonne UniversitéParis F-75006France Service de Rhumatologie Pédiatrique Centre de Référence des Maladies Auto-Inflammatoires Rares et des AmylosesCHU de Bicêtrele Kremlin Bicêtre F-94270France UniversitéParis Descartes Sorbonne Paris CitéParis F-75006France Laboratoire d’Immunologie et d’Allergologie/CHU d’Angers Universitéd’Angers/INSERM Unité1232/LabEx IGO“Immuno-Graft-Onco”Angers F-49933France

Basophils are rare *** representing only~0.5%of all leukocytes,basophils have several important physiological functions.1,2 Although basophils lack the classic features of professional antigen-presenting cells,3–7 through the secretion of cytokines,they orient the immune response by polarizing Th2 differentiation and supporting B-cell differentiation and class *** are also critical for mediating protection against helminth infection.1,2,8,9 Basophils receive activation signals from diverse *** is well recognized that cytokines such as IL-3,granulocyte–macrophage colony-stimulating factor(GM-CSF),thymic stromal lymphopoietin(TSLP)and IL-33;various toll-like receptor ligands;allergen-bound IgE provide activation signals to basophils and induce the release of inflammatory mediators.10–15 In addition,several reports have also demonstrated the existence of anti-IgE autoantibodies that possess the capacity to induce basophil activation in patients with chronic spontaneous urticaria(CSU),atopic or non-atopic asthma or autoimmune disease.16–21 However,isolation and functional exploration of such anti-IgE IgG autoantibodies from either healthy donors or patients have not been attempted *** using a pooled normal IgG preparation from healthy donors,specifically intravenous immunoglobulin G(IvIG)22 that represents the complete IgG repertoire of a normal individual,we attempted to address this outstanding question in the field.

关键词： activation attempted IgE

Artificial neural network approach for analyzing mutual coupling in a rectangular MIMO antenna

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Frontiers of Electrical and Electronic Engineering in China 2012年第3期7卷 293-298页

作者： k. SRI RAMA kRISHNA k. jagadeesh BABU J. LAkSHMI NARAYANA L. PRATAP REDDY G. v. SUBRAHMANYAM Department of Electronics and Communication Engineering VRSiddhartha Engineering College Vijayawada India k. jagadeesh BABU J. LAKSHMI NARAYANADepartment of Electronics and Communication Engineering St. Ann'sCollege of Engineering and Technology Chirala India Department of Electronics and Communication Engineering JNTUCollege of Engineering Hyderabad India Department of Electronics and Communication Engineering AcharyaNagarjuna University Guntur India

A wideband rectangular patch antenna resonat- ing at 3.5 GHz and 8 GHz frequencies is developed on a flexible substrate, which can be used for wearable applications. The proposed antenna gives a wide impe- dance bandwidth of 116%, operating from *** to 9.5 GHz, covering most of the ultra-wideband （UWB） operating frequency range. A two-element multiple-input multiple-output （MIMO） system is developed using the proposed antenna, and the mutual coupling between the two antennas for various separations and frequencies is analyzed by using artificial neural networks （ANNs）. The neural structure is trained by using different ANN algorithms and a comparative study is made between them. It is shown that, quasi-Newton （QN） and quasi- Newton multi layer perceptron （QN-MLP） algorithms are better in terms of training, testing errors, and correlation coefficient.

关键词： flexible substrate multiple input multipleoutput (MIMO) systems artificial neural networks (ANNs) mutual coupling impedance bandwidth

Intravenous immunoglobulin-mediated expansion of regulatory T cells in autoimmune patients is associated with increased prostaglandin E2 levels in the circulation

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Cellular & Molecular Immunology 2015年第5期12卷 650-652页

作者： Mohan S Maddur Jamma Trinath Magalie Rabin Francis Bolgert Moneger Guy Jean-Michel vallat Laurent Magy kithiganahalli N Balaji Srini v.k.veri jagadeesh Bayry Institut National de la Sante et de la Recherche Medicale Paris France Centre de Recherche des Cordeliers Equipe - Immunopathology and Therapeutic Immunointervention Paris France Sorbonne Universites - UPMC Univ Paris 6 Paris France Universite Paris Descartes Paris France Department of Microbiology and Cell Biology Indian Institute of Science Bangalore India Centre de Reference 'Neuropathies Peripheriques Rares' et Service de Neurologie Hopital Universitaire Limoges Limoges France Reanimation Neurologique Neurologie 1 Hopital de la Pitie-Salpetriere Paris France International Associated Laboratory IMPACT (Institut National de la Sante et de la Recherche Medicale France -Indian Council of Medical Research India) National Institute of Immunohaematology Mumbai India

CD4＋FoxP3＋ regulatory T cells （Tregs） are immunosuppressive cells that are critical for immune tolerance. Several studies have demonstrated that one of the anti-inflammatory mechanisms of action of intravenous immunoglobulin （Wig） involves the expansion of Tregs. Recently, we demonstrated that IvIgmediated Treg expansion involves the cyclooxygenase-2 （COX-2）-dependent induction of prostaglandin E2 （PGE2） in human dendritic cells （DCs）. However, the validity of these findings in autoimmune patients is lacking.

关键词： associated increased prostaglandin