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The Effects of Ground and Treadmill Running on Energy Metabolism and Muscle Contractile Properties:A Randomized Cross-Over Study

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Journal of Science in Sport and Exercise 2022年第2期4卷 109-118页

作者： Yuan Zhou Jian-gang Chen Xiao-long Li Xin-liang Pan Yi-zheng Zhou Zheng-ao Li Zhi-cheng Liang Jia-min Long Ming-ze Qin Jing Zhang Bing Shi Bing-jun Wan ai-ping chi Wen-fei Zhu Ke Ning Yu-liang Sun School of Physical Education Shaanxi Normal UniversityNo.620 West Chang’an StreetChang’an DistrictXi’an 710119ShaanxiChina School of Kinesiology Beijing Sport UniversityNo.48 Xinxi RoadHaidian DistrictBeijing 100084China

Purpose This study aimed to compare the effects of ground and treadmill running on energy metabolism and muscle con-tractile properties,providing a basis for the general public to choose running *** Ten male college students(age,20.10±1.53 years;height,176.20±5.49 cm;weight,72.14±8.25 kg;body fat percent,12.41%±4.65%)were recruited in this *** expenditure(EE)was measured using the accelerometer(GT9X)combined with specific estimation *** heart rate(HR)was measured using a heart rate band(Polar).Muscle contractile properties were assessed by measuring muscle displacement(Dm)and contraction velocity(Vc)using tensiomyography(TMG-S1).Blood glucose(Glu)and lactate(Lac)were measured by portable devices(eB-G and Lactate Scout).The running speed was 9 km/h and the duration was 25 ***-way ANOVA(protocol×time)was used to analyze the effect of running protocols on energy metabolism and muscle contractile *** EE of treadmill running was significantly higher than EE of ground running(protocol main effect,Pain effect,P=0.009).The interaction of different running protocols and testing times on Lac was significant(P=0.025),but all results of the simple effects analysis were not statisti-cally significant(P>0.05).Conclusion Our study found a difference in energy expenditure between treadmill and ground running at 9 km/h with duration of 25 *** addition,treadmills are more likely to cause a decrease in muscle displacement distance of the rectus femoris measured after exercise than ground *** studies are needed to further investigate whether the differences are induced by internal metabolism or the environmental cond

关键词： Ground running Treadmill running Energy expenditure Muscle contractile properties Blood glucose Blood lactate

Deciphering Potential Correlations between New Biomarkers and Pattern Classification in chinese Medicine by Bioinformatics:Two Examples of Rheumatoid Arthritis

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chinese Journal of Integrative Medicine 2021年第6期27卷 465-469页

作者： ZHANG chi LI Li ZHANG Ge CHEN Ke-ji LU ai-ping Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing(100700)China Institute for Advancing Translational Medicine in Bone and Joint Diseases Hong Kong Baptist UniversityHong Kong SARChina Cardiovascular Disease Centre Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing(100091)China

Biological complexity and the need for personalized medicine means that biomarker development has become increasingly ***,new paradigms for research need to be created that bring together a different classifier of *** potential solution is collaboration between biomarker development and chinese medicine pattern *** this article,two examples of rheumatoid arthritis are discussed,including a new biomarker candidate casein kinase 2 interacting protein 1(CKIP-1)and a micro RNA *** authors obtained a"snapshot"of pattern classification with disease in biomarker *** analyses revealed underlying biological functions of two biomarker candidates,in varying degrees,are correlated with chinese medicine pattern of rheumatoid *** authors'initial attempt can provide a new window for studying the win-win potential correlation between the biomarkers and pattern classification in chinese medicine.

关键词： chinese medicine pattern classification biomarker rheumatoid arthritis

Possible Roles of Diet in the Etiology of Rheumatoid Arthritis:A Systematic Review

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World Journal of Traditional chinese Medicine 2016年第3期2卷 25-35页

作者： chi Zhang Ka-Miu Chan ai-ping Lu School of chinese Medicine Hong Kong Baptist University Hong Kong chinese Medicine Clinical study Center Hong Kong Baptist University Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical Sciences

Background:There is a growing interest in the possible role of diet in the prevention of rheumatoid arthritis(RA).However,the evidence for diet having a role in the etiology of RA is inconsistent,sometimes ***:To critically appraise the literature to pool the results of studies to clarify the relation between diet risk and ***:We performed a systematic review using guideline-recommended methodology to evaluate the association between pre-illness diet or diet pattern and the risk of subsequent RA ***:A total of 25 studies met the inclusion *** include 13 cohort studies,10 case-control studies and 2 nested case-control studies,with a total of 1279810 *** were new evidences of a protective effect of long term consumption of *** sodium intake was associated with an increased risk of *** intake has consistently been shown to have no effect on the development of *** diet pattern,Vitamin D intake,and the consumption of long-chain omega-3 acids were not associated with an increased/decreased risk of RA in every two *** were non-statistically significant association between RA and sugar-sweetened soda,red meat,vegetable and fruits in each single *** association between coffee,tea and RA was consistent,and here exists an inverse relationship between olive oil and *** to the heterogeneity of study designs and analyses,the results could not be ***:The results of this SR indicate that alcohol consumption and sodium intake may be associated with RA risk,especially evidence from recent *** of some discordant results,the debate continues on whether some other dietary intakes increase or decrease RA risk.

关键词： Diet Rheumatoid Arthritis Systematic review

AtomSets as a hierarchical transfer learning framework for small and large materials datasets

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npj Computational Materials 2021年第1期7卷 1575-1583页

作者： chi Chen Shyue ping Ong Department of NanoEngineering University of California San Diego9500 Gilman DrMail Code 0448La JollaCA 92093-0448USA

Predicting properties from a material’s composition or structure is of great interest for materials *** learning has recently garnered considerable interest in materials predictive tasks with low model errors when dealing with large materials ***,deep learning models suffer in the small data regime that is common in materials *** we develop the AtomSets framework,which utilizes universal compositional and structural descriptors extracted from pre-trained graph network deep learning models with standard multi-layer perceptrons to achieve consistently high model accuracy for both small compositional data(130,000).The AtomSets models show lower errors than the graph network models at small data limits and other non-deep-learning models at large data *** also transfer better in a simulated materials discovery process where the targeted materials have property values out of the training data *** models require minimal domain knowledge inputs and are free from feature *** presented AtomSets model framework can potentially accelerate machine learning-assisted materials design and discovery with less data restriction.

关键词： Sets framework hierarchical

CHEMICAL BEHAVIOR OF CERIUM ELEMENT IN ROCK WEATHERING SYSTEM

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中国有色金属学会会刊：英文版 1999年第1期9卷 160-166页

作者： chi, Ru'an Zhu, Guocai Zhang, ping Xu, Yinghui Tsinghua Univ Beijing China

１ＩＮＴＲＯＤＵＣＴＩＯＮＴｈｅｅｌｅｃｔｒｏｎｉｃｓｔｒｕｃｔｕｒｅｏｆｇｒｏｕｎｄｓｔａｔｅａｔｏｍｃｅｒｉｕｍｉｓＸｅ４ｆ１５ｄ１６ｓ２，ａｎｄｔｈｅｅｌｅｃｔｒｏｎｉｃｓｔｒｕｃｔｕｒｅｏｆｔｒｉｖａｌｅｎｔ... 详细信息

１ＩＮＴＲＯＤＵＣＴＩＯＮＴｈｅｅｌｅｃｔｒｏｎｉｃｓｔｒｕｃｔｕｒｅｏｆｇｒｏｕｎｄｓｔａｔｅａｔｏｍｃｅｒｉｕｍｉｓＸｅ４ｆ１５ｄ１６ｓ２，ａｎｄｔｈｅｅｌｅｃｔｒｏｎｉｃｓｔｒｕｃｔｕｒｅｏｆｔｒｉｖａｌｅｎｔｏｘｉｄｉｚｉｎｇｓｔａｔｅｉｓＸ...

关键词： cerium rare earth ore weathering system chemical behavior

Application of Nanopore Sequencing Technology in the Clinical Diagnosis of Infectious Diseases

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Biomedical and Environmental Sciences 2022年第5期35卷 381-392页

作者： ZHANG Lu Lu ZHANG chi PENG Jun ping NHC Key Laboratory of Systems Biology of Pathogens Institute of Pathogen BiologyChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100176China Key Laboratory of Respiratory Disease Pathogenomics Chinese Academy of Medical SciencesBeijing 100176China

Infectious diseases are an enormous public health burden and a growing threat to human health *** or classic recurrent pathogens,or pathogens with resistant traits,challenge our ability to diagnose and control infectious *** sequencing technology has the potential to enhance our ability to diagnose,interrogate,and track infectious diseases due to the unrestricted read length and system *** review focuses on the application of nanopore sequencing technology in the clinical diagnosis of infectious diseases and includes the following:(i)a brief introduction to nanopore sequencing technology and Oxford Nanopore Technologies(ONT)sequencing platforms;(ii)strategies for nanopore-based sequencing technologies;and(iii)applications of nanopore sequencing technology in monitoring emerging pathogenic microorganisms,molecular detection of clinically relevant drug-resistance genes,and characterization of disease-related microbial ***,we discuss the current challenges,potential opportunities,and future outlook for applying nanopore sequencing technology in the diagnosis of infectious diseases.

关键词： Nanopore sequencing Infectious diseases Pathogen Oxford Nanopore Technologies

Text Mining of Rheumatoid Arthritis and Diabetes Mellitus to Understand the Mechanisms of chinese Medicine in Different Diseases with Same Treatment

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chinese Journal of Integrative Medicine 2018年第10期24卷 777-784页

作者： ZHAO Ning ZHENG Guang LI Jian ZHAO Hong-yan LU Cheng JIANG Miao ZHANG chi GUO Hong-tao LU ai-ping Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical Sciences School of Information Science and Engineering Lanzhou University School of Basic Medical Sciences Beijing University of Chinese Medicine Institute of Basic Theory for chinese Medicine China Academy of Chinese Medical Sciences School of chinese Medicine Hong Kong Baptist University

Objective： To identify the commonalities between rheumatoid arthritis （RA） and diabetes mellitus （DM） to understand the mechanisms of chinese medicine （CM） in different diseases with the same treatment. Methods： A text mining approach was adopted to analyze the commonalities between RA and DM according to CM and biological elements. The major commonalities were subsequently verified in RA and DM rat models, in which herbal formula for the treatment of both RA and DM identified via text mining was used as the intervention. Results： Similarities were identified between RA and DM regarding the CM approach used for diagnosis and treatment, as well as the networks of biological activities affected by each disease, including the involvement of adhesion molecules, oxidative stress, cytokines, T-lymphocytes, apoptosis, and inflammation. The Ramulus Cinnamomi-Radix Paeoniae Alba-Rhizoma Anemarrhenae is an herbal combination used to treat RA and DM. This formula demonstrated similar effects on oxidative stress and inflammation in rats with collagen-induced arthritis, which supports the text mining results regarding the commonalities between RA and DM. Conclusion： Commonalities between the biological activities involved in RA and DM were identified through text mining, and both RA and DM might be responsive to the same intervention at a specific stage.

关键词： text mining rheumatoid arthritis diabetes mellitus different diseases with same treatment chinese medicine

Ligand-controlled NiH-catalyzed regiodivergent hydroalkylation of 2-alkenylazaarenes

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Science china Chemistry 2024年第6期67卷 1935-1940页

作者： Ya-ping Shao Zhuo-Min chi Yong-Min Liang State Key Laboratory of Applied Organic Chemistry School of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou730000China

A nickel-hydride(Ni H)-catalyzed migratory and nonmigratory hydroalkylation reaction of 2-alkenyl azaarenes with alkyl iodines has been established through strategic modulation of N-or P-donor *** method enables the synthesis of diverseβ-orγ-branched aromatic *** mild regiodivergent protocols exhibit wide substrate scope,excellent functional tolerance,and great reaction yield with remarkable ***,deuterium labeling studies reveal Ni H-catalyzed interrupted chain-walking mode as the mechanism behind remotedβ-selective hydroalkylation reaction—an interesting phenomenon mediated through aromatic imine directing groups.

关键词： NiH regiodivergent hydroalkylation azaarenes interrupted chain-walking

LARGE EDDY SIMULATION OF VERTICAL JET IMpingEMENT WITH A FREE SURFACE

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Journal of Hydrodynamics 2006年第2期18卷 148-155页

作者： CHEN Yong-ping LI chi-wai ZHANG Chang-kuang Departmentof Civil and Structural Engineering The Hongkong Polytechnic University Hongkong China College of Traffic and Ocean Engineering Hohai University Nanjing 210098 China

The flow characteristics of a 2D slot jet vertically impinging on free surfaces are numerically investigated by the Large Eddy Simulation （LES） with a dynamic Sub-Grid Scale （SGS） model. The σ-coordinate transformation is introduced to map the depth-variable physical domain to a depth-uniform computational domain. The split-operator scheme, which splits the solution procedure into advection, diffusion and pressure propagation steps, is employed to solve the instantaneous velocity and pressure field. A fully nonlinear Lagrange-Euler method is used to compute the free surface elevation. The numerical results show that the jet retains good self-similarity in the Zone of Eestablished Flow （ZEF）, while the turbulence of jet shifts gradually from isotropic to anisotropic in the Zone of Surface Impingement （ZSI）. When the jet approaches the free surface, the centerline velocity decreases rapidly and the flow is deflected by the free surface. Two symmetrical surface jets are formed in the Zone of Horizontal Jets （ZHJ）. An approximate Guassian distribution of super-elevation is also formed on the free surface. The computed results are in good agreement with the available experimental data.

关键词： Large Eddy Simulation (LES) 2D slot jet free surface