Possible Roles of Diet in the Etiology of Rheumatoid Arthritis:A Systematic Review

作     者：Chi Zhang Ka-Miu Chan Ai-Ping Lu 

作者机构：School of Chinese MedicineHong Kong Baptist University Hong Kong Chinese Medicine Clinical study CenterHong Kong Baptist University Institute of Basic Research in Clinical MedicineChina Academy of Chinese Medical Sciences 

出 版 物：《World Journal of Traditional Chinese Medicine》 (世界中医药杂志（英文）)

年 卷 期：2016年第2卷第3期

页      面：25-35页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China(No.81503449) 

主　　题：Diet Rheumatoid Arthritis Systematic review 

摘      要：Background:There is a growing interest in the possible role of diet in the prevention of rheumatoid arthritis(RA).However,the evidence for diet having a role in the etiology of RA is inconsistent,sometimes ***:To critically appraise the literature to pool the results of studies to clarify the relation between diet risk and ***:We performed a systematic review using guideline-recommended methodology to evaluate the association between pre-illness diet or diet pattern and the risk of subsequent RA ***:A total of 25 studies met the inclusion *** include 13 cohort studies,10 case-control studies and 2 nested case-control studies,with a total of 1279810 *** were new evidences of a protective effect of long term consumption of *** sodium intake was associated with an increased risk of *** intake has consistently been shown to have no effect on the development of *** diet pattern,Vitamin D intake,and the consumption of long-chain omega-3 acids were not associated with an increased/decreased risk of RA in every two *** were non-statistically significant association between RA and sugar-sweetened soda,red meat,vegetable and fruits in each single *** association between coffee,tea and RA was consistent,and here exists an inverse relationship between olive oil and *** to the heterogeneity of study designs and analyses,the results could not be ***:The results of this SR indicate that alcohol consumption and sodium intake may be associated with RA risk,especially evidence from recent *** of some discordant results,the debate continues on whether some other dietary intakes increase or decrease RA risk.