检索结果-南通市图书馆

Multimodality management for chronic subdural hematoma in China: protocol and characteristics of an ambidirectional, nationwide, multicenter registry study

引用

中华神经外科杂志(英文) 2024年第2期10卷 1-10页

作者： Liu Tao Zhao zhihao Huang Jinhao Zhu Xide Chen Weiliang Lin Kun Yu Yunhu Li Zhanying Fan Yibing Liu Mingqi Nie Meng Liu Xuanhui Gao Chuang quan Wei Qian Yu Wu Chenrui Yuan Jiangyuan Wu Di Lv Chuanxiang Dong Shiying Mi Liang Tian Yu Tian Ye Zhang Jianning Jiang Rongcai Department of Neurosurgery Tianjin Medical University General Hospital Tianjin China Ministry of Education Tianjin Neurological Institute Key Laboratory of Post Neuro-injury Neuro-repair and Regeneration in Central Nervous System Tianjin Medical University General Hospital Tianjin China Department of Neurosurgery Linyi People’s Hospital Shandong China Department of Neurosurgery Haining People’s Hospital Zhejiang China Department of Neurosurgery Fujian Provincial Hospital Fujian China Department of Clinical Research Center for Neurological Disease the People’s Hospital of HongHuaGang District of ZunYi Guizhou China Department of Neurosurgery Kailuan General Hospital Hebei China Department of Neurosurgery Tianjin First Central Hospital Tianjin China Department of Neurosurgery The First Hospital of Jilin University Changchun China

Background Despite its prevalence, there is ongoing debate regarding the optimal management strategy for chronic subdural hematoma (CSDH), reflecting the variability in clinical presentation and treatment outcomes. This ambidirectional, nationwide, multicenter registry study aims to assess the efficacy and safety of multimodality treatment approaches for CSDH in the Chinese ***/design A multicenter cohort of CSDH patients from 59 participating hospitals in mainland China was enrolled in this study. The treatment modalities encompassed a range of options and baseline demographics, clinical characteristics, radiographic findings, and surgical techniques were documented. Clinical outcomes, including hematoma resolution, recurrence rates, neurological status, and complications, were assessed at regular intervals during treatment, 3 months, 6 months, 1 year, and 2 years *** Between March 2022 and August 2023, a comprehensive cohort comprising 2173 individuals who met the criterion was assembled across 59 participating clinical sites. Of those patients, 81.1% were male, exhibiting an average age of 70.12 ± 14.53 years. A historical record of trauma was documented in 48.0% of cases, while headache constituted the predominant clinical presentation in 58.1% of patients. The foremost surgical modality employed was the burr hole (61.3%), with conservative management accounting for 25.6% of cases. Notably, a favorable clinical prognosis was observed in 88.9% of CSDH patients at 3 months, and the recurrence rate was found to be 2.4%.Conclusion This registry study provides critical insights into the multimodality treatment of CSDH in China, offering a foundation for advancing clinical practices, optimizing patient management, and ultimately, improving the quality of life for individuals suffering from this challenging neurosurgical *** registration ChiCTR2200057179

关键词： Chronic subdural hematoma Multimodality therapy Outcome Recurrence

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

掺钕钇铝钙钛晶体激光结合两种再矿化制剂与早期釉质龋的再矿化

引用

中国组织工程研究 2024年第3期28卷 360-365页

作者：许颖华刘婧尤权文志豪高璐上海市浦东新区眼病牙病防治所上海市200011 大连医科大学口腔医学院辽宁省大连市116044

背景:近年来,多种激光被广泛应用于口腔医学相关的各种疾病,包括龋病的预防及治疗。目的:探讨掺钕铝酸钇晶体(neodymium-doped:yttrium aluminum perovskite,Nd:YAP)激光联合两种再矿化制剂对早期釉质龋再矿化的作用。方法:将60颗牙釉... 详细信息

背景:近年来,多种激光被广泛应用于口腔医学相关的各种疾病,包括龋病的预防及治疗。目的:探讨掺钕铝酸钇晶体(neodymium-doped:yttrium aluminum perovskite,Nd:YAP)激光联合两种再矿化制剂对早期釉质龋再矿化的作用。方法:将60颗牙釉质块体外建立人工龋模型后,随机分为6组(n=10):A组不进行任何处理,行体外pH循环;B组进行护牙素(主要成分为酪蛋白磷酸钙复合体)再矿化处理,行体外pH循环;C组进行舒适达牙膏(主要成分为生物活性玻璃)再矿化处理,行体外pH循环;D组进行Nd:YAP激光照射,行体外pH循环;E组进行Nd:YAP激光照射,然后进行护牙素再矿化处理,行体外pH循环;F组进行Nd:YAP激光照射,然后舒适达牙膏再矿化处理,行体外pH循环;再矿化处理2次/d,实验周期20 d。G组为正常对照,未致龋,未进行再矿化处理,仅行体外pH循环。实验结束后,检测各组牙釉质表面的显微硬度、形貌与Ca/P比值。结果与结论:①B、C、D组牙釉质表面的硬度值高于A组(P<0.0001),E、F组牙釉质表面的硬度值明显高于B、C、D组(P<0.0001),F组牙釉质表面的硬度值明显高于E组(P<0.0001);②扫描电镜下可见,A组牙釉质表面存在大量的脱矿孔隙;B组牙釉质表面有矿物质沉积,沉积不均匀且较为疏松;C组牙釉质表面有大量矿物质沉积,且钙化团块间可见脱矿孔隙;D组牙釉质表面较为平整,脱矿孔隙较A组明显变小,釉柱间质有破坏;E组牙釉质表面矿物质沉积较厚,脱矿孔隙明显减少;F组牙釉质表面沉积的矿化物最为致密且均匀,脱矿孔隙细小;③B、C组牙釉质表面Ca/P比值明显高于A组(P<0.0001),E组牙釉质表面Ca/P比值明显高于B、C、D组(P<0.0001),F组牙釉质表面Ca/P比值高于E组(P<0.001);③结果显示,生物活性玻璃、酪蛋白磷酸钙复合体、Nd:YAP激光在牙釉质脱矿后均具有促进牙釉质表面再矿化的作用,Nd:YAP激光联合生物活性玻璃或酪蛋白磷酸钙复合体能进一步加强牙釉质龋的再矿化作用,其中Nd:YAP激光和生物活性玻璃的联合使用效果最佳。

关键词：牙釉质龋再矿化酪蛋白磷酸钙复合体生物活性玻璃掺钕钇铝钙钛晶体(Nd:YAP)激光显微硬度钙磷比联合治疗

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Is Smoking a Risk Factor of Hypertension within Obstructive Sleep Apnea Patients

Is Smoking a Risk Factor of Hypertension within Obstructive ...

引用

中华医学会呼吸病学年会——2013（第十四次全国呼吸病...

作者： Lijun Jiang zhihao quan Jianhong Liu Yuping Xie Zhijian Lei Bifang Liang Hualin Tang Sleep-Disordered Breathing Center of Guangxi People’s Hospital of Guangxi Zhuang Autonomous Region

Objective To explore the possible relationship between smoking and hypertension within the obstructive sleep apnea patients. Methods Subjects aged over 18 years were recruited from May 2009 to July 2012 inGuangxi Zhuang Autonomous Region People’s *** polysomnography(PSG) was performed for each *** measurements,such as height,weight,were measured before *** habits were quantified by using retrospective

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Effect of smoking habits on Obstructive sleep apnea and nocturnal hypoxemia

Effect of smoking habits on Obstructive sleep apnea and noct...

引用

中华医学会呼吸病学年会——2013（第十四次全国呼吸病...

作者： zhihao quan Jianhong Liu yuping Xie Zhijian Lei Bifang Liang Lijun Jiang hualin Tang Sleep-Disordered Breathing Center of Guangxi People’s Hospital of Guangxi Zhuang Autonomous Region

Objective To evaluate the effect of smoking habits on Obstructive sleep apnea and nocturnal hypoxemia. Methods Data were collected from the chart review of 1364 patients at our sleep-disordered breathing center. The inclusion criteria for this data were:adult patients (30 to 70 years of age ),under full-night polysomnograph *** habits were quantified by using retrospective questionnaires. Results 949 patients were diagnosed as having OSA, defined by an apnea-hypopnea index(AHI ) of greater than 15 events per *** with AHI between 5 and *** compared their smoking habits and

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

改进人工势场引导的双向扩展随机树路径规划算法

引用

探测与控制学报 2024年第3期46卷 86-93页

作者：衷卫声闵志豪权略熊剑郭杭张强南昌大学先进制造学院江西南昌330000 南昌大学信息工程学院江西南昌330000

针对地面移动机器人在复杂环境之下要求规划路径实时性强、路线平滑度高、避障精确完备等需求,在快速扩展随机树算法(RRT)的基础之上,提出一种由改进人工势场法(APF)引导的双向扩展随机树算法(APF-Bi-RRT^(*))。首先,在每次迭代的过程... 详细信息

针对地面移动机器人在复杂环境之下要求规划路径实时性强、路线平滑度高、避障精确完备等需求,在快速扩展随机树算法(RRT)的基础之上,提出一种由改进人工势场法(APF)引导的双向扩展随机树算法(APF-Bi-RRT^(*))。首先,在每次迭代的过程之中两棵随机树同时分别从起始点和目标点进行扩展,以加快算法收敛速度;其次,在算法随机树生长方向上,引入目标偏置策略来优化随机子节点的选取,并在随机树和障碍物中加入人工势场分量,限制路径方向选择的随机性,改进算法克服引力和斥力过大导致陷入局部最优值或目标不可达的问题;最后,在形成锯齿型规划路径之上应用一种采样优化和关键节点平滑策略,进一步缩短和平滑原路径的总距离。对比实验结果证明,该算法既克服了传统随机树算法的节点盲目扩展的问题,又兼顾了生成路径的效率和平滑性,与目标偏置RRT算法相比,在规划路径长度上减少了9.7%左右,在运行时间上缩短了65.3%左右,在算法迭代次数上减少了78.2%左右。

关键词：改进人工势场法双向快速扩展随机树路径规划曲线采样优化

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Luminescence modulation of ultrasmall gold clusters by aromatic ligands

引用

Nano Research 2023年第8期16卷 11366-11374页

作者： Xue-Jing Zhai Jia-Hua Hu Jianxin Guan Yubing Si Xi-Yan Dong Peng Luo Fangfang Pan zhihao Yu Runping Han Shuang-quan Zang College of Chemistry Zhengzhou UniversityZhengzhou 450001China College of Chemistry and Chemical Engineering Henan Polytechnic UniversityJiaozuo 454003China College of Chemistry and Molecular Engineering Peking UniversityBeijing 100871China College of Chemistry Central China Normal UniversityWuhan 430079China

Luminescence is one of the most important properties for metal nanoclusters;however,clearly revealing its origin remains *** different luminescence properties of the two prototypical 8e nanoclusters Au_(11)and Au_(13)remain elusive—Au_(11)is always nonluminescent,whereas Au_(13)is *** this work,by using a designed unique aromatic ligand(quinoline-2-thiol),we obtained new atomically precise phosphine-thiolate-protected neutral Au_(11)-SH and cationic Au_(13)-*** comparison with the classic phosphine-halide-protected Au_(11)-Cl and Au_(13)-Cl,the Cl-to-thiol alteration triggered room-temperature luminescence of the Au_(11)core and dramatically modulated that of the Au_(13)*** ultraviolet/infrared(UV/IR)spectroscopy,which is sensitive to organic aromatic groups,together with ultrafast transient absorption(TA)spectroscopy unprecedently revealed a relaxation process from the ligand to core state affecting the dynamics in excited states and some critical intermediate states favouring efficient room-temperature emission of these *** work provides some new insights into the origin of photoluminescence of metal nanoclusters and opens an avenue to modulate the dynamics of their excited states using aromatic ligands,which would have direct applications in lighting,light harvesting,and photocatalysis.

关键词： metal nanoclusters luminescence ligand modification

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

吸烟与阻塞性睡眠呼吸暂停低通气综合征的相关性

引用

中华医学杂志 2014年第10期94卷 733-736页

作者：全志豪刘建红谢宇萍雷志坚梁碧芳蒋丽君唐华林广西壮族自治区人民医院广西睡眠呼吸疾病诊疗中心南宁530021

目的了解吸烟与阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的相关性。方法对2009年7月1日至2012年6月30日到广西睡眠呼吸疾病诊疗中心就诊，30～65岁睡眠或睡眠呼吸疾病患者2243例行整夜多导睡眠图（PSG）检查，并采用回顾性调查问卷，... 详细信息

目的了解吸烟与阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的相关性。方法对2009年7月1日至2012年6月30日到广西睡眠呼吸疾病诊疗中心就诊，30～65岁睡眠或睡眠呼吸疾病患者2243例行整夜多导睡眠图（PSG）检查，并采用回顾性调查问卷，了解患者的吸烟情况。按睡眠呼吸暂停低通气指数（AHI）将患者分组为OSAHS组（AHI≥15次／h）及无OSAHS组（AHI〈50次／h）。分析吸烟及吸烟量与OSAHS之间的联系。结果2243例患者中903例被排除，最终1340例纳入分析，其中OSAHS组929例，非OSAHS组411例。OSAHS组吸烟率为47．1％，非OSAHS组吸烟率为25．5％。在控制了年龄、体重、性别、饮酒史后，吸烟组患OSAHS的条件OR值为1．446（95％CI：1．079～1．939，P=02013）；重度吸烟未戒烟组（≥30包·年）患OSAHS的条件OR值为2．382（95％CI：1．127—4．375，P=0．012）。未戒烟OSAHS组比不吸烟OSAHS组有更长的缺氧时间比[（20．5±23．1）％比（15．6±18．8）％，P=0．004]及更低的血氧饱和度[（69．4±10．3）％比（73．2±9．7）％，P=0．000]，而戒烟OSAHS组与不吸烟OSAHS组间差异无统计学意义。重度吸烟OSAHS组出现夜间血氧饱和度〈90％的时间占总睡眠时间比≥5％者条件OR值是1．893（95％CI：1．046—3．423，P=0．035）。结论吸烟与OSAHS有明显的相关性；吸烟，特别是重度吸烟者OSAHS风险更高。吸烟加重了OSAHS组的夜间低氧血症。

关键词：睡眠呼吸暂停,阻塞性吸烟肥胖低通气综合征低氧血症

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Recent advances in autofluorescence-free biosensing and bioimaging based on persistent luminescence nanoparticles

引用

Chinese Chemical Letters 2019年第9期30卷 1547-1556页

作者： Qiaosong Lin zhihao Li quan Yuan Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education) College of Chemistry and Molecular Sciences Wuhan University

Persistent luminescence nanoparticles (PLNPs) are a series of emerging luminescent nanomaterials which can emit persistently after ceasing the external excitation. Due to the long decay time of persistent luminescence, the background autofluorescence in complex sample and tissues can be effectively eliminated, thus significantly improving the sensitivity of bioanalysis. Besides, such a long decay time of luminescence also makes PLNPs valuable for long-term bioimaging. Benefiting from these merits, PLNPs have been widely used for biomedical applications, especially biosensing and bioimaging. In this review,we conclude the progress in the application of PLNPs at biosensing and bioimaging in recent years, and also provide our understanding of the prospects.

关键词： Analysis Biosensing Bioimaging Persistent luminescence Nanoparticles

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Recent progress in background-free latent fingerprint imaging

引用

Nano Research 2018年第10期11卷 5499-5518页

作者： Yingqian Wang Jie Wang Qinqin Ma zhihao Li quan Yuan Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education) College of Chemistry and MolecularSciences Wuhan University Wuhan 430072 China

Owing to their unique pattern and abundant chemical composition, latent fingerprints （LFPs） can serve as ＂ID cards＂ and ＂information banks＂ of donors and therefore are valuable for forensic investigation, access control, and even medical diagnosis. LFP imaging has attracted considerable attention, and a great variety of contrast agents has been developed. In LFP imaging, background signals such as background fluorescence from the underlying surface can seriously blur the LFP images and decrease imaging sensitivity; thus, great efforts have been made to eliminate background interference. Here, we stratify the recent progress in background-free LFP imaging by making use of the difference in properties between contrast agents and background compounds. For example, near-infrared （NIR） light-activatable contrast agents can efficiently remove background signals in LFP imaging because the background compounds cannot be excited by NIR light, showing that the difference in excitation properties between contrast agents and background compounds can be employed to eliminate background interference. This review is organized around background-free LFP imaging based on the difference in optical properties between contrast agents and background compounds：（i） different excitation wavelengths, （ii） different emission wavelengths, （iii） different luminescence lifetime values, （iv） different plasmonic properties, （v） different photothermal properties, and （vi） different electrochemiluminescence properties.

关键词： latent fingerprints background interference upconversion persistent luminescence nanoparticles

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rational design and biomedical applications of DNA-functionalized upconversion nanoparticles

引用

Chinese Chemical Letters 2018年第9期29卷 1321-1332页

作者： Xinwen Liu Meng Liu Jiajia Chen zhihao Li quan Yuan Key laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education) College of Chemistry and Molecular Sciences Wuhan University

Lanthanide-doped upconversion nanoparticles （UCNPs） offer unique advantages in term of low autofluorescence, high signal-to-noise ratio and deep tissue penetration, and have attracted considerable attention in biomedical applications. DNA, beyond the properties of self-assembly, also exhibits multiple functions such as molecular recognition, drug loading capacity and therapeutic effect. In this regard, the combination of UCNPs and DNA offers a promising and powerful platform for potential applications in biosensing, bioimaging and disease therapy. In this review, we mainly introduce recent progresses of DNA-functionalized upconversion materials, providing an overview of the design and applications in biosensing, bioimaging and therapy. The challenges and future perspectives are also discussed, aiming to promote their applications in material science and biomedicine.

关键词： Lanthanide-doped upconversion nanoparticles DNA Biosensor Bioimaging Disease therapy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：