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Robust ensemble of metamodels based on the hybrid error measure

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Frontiers of Mechanical Engineering 2021年第3期16卷 623-634页

作者： Shuai HUANG Bo WU Xin ZHANG Aman ELMI Youmin HU wenwen jin School of Mechanical Science and Engineering Huazhong University of Science and TechnologyWuhan 430074China College of Life Science and Technology Huazhong University of Science and TechnologyWuhan 430074China

Metamodels have been widely used as an alternative for expensive physical experiments or complex,time-consuming computational simulations to provide a fast but accurate ***,challenge remains in the prior determination of the most suitable metamodel for a particular case because of the lack of information about the actual behavior of a *** addition,existing studies on metamodels have largely restricted on solving deterministic problems(e.g.,data from finite element models),whereas some real-life engineering problems(e.g.,data from physical experiment)are stochastic problems with noisy *** this work,a robust ensemble of metamodels(EMs)is proposed by combining three regression stand-alone metamodels in a weighted sum *** weight factor is adaptively determined according to the hybrid error metric,which combines global and local error measures to improve the accuracy of the ***,three typical individual metamodels that can filter noise are selected to construct the EMs to extend their application in practical engineering *** well-known benchmark problems with different levels of noise and three engineering problems are used to verify the effectiveness of the proposed *** show that the proposed EMs have higher accuracy and robustness than the individual metamodels and other typical EMs in major cases.

关键词： metamodel ensemble of metamodels hybrid error measure stochastic problem

Association of TCF7L2 rs7903146 Gene Polymorphism with the Risk of NAFLD and CAD in the Chinese Han Population

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Journal of Clinical and Translational Hepatology 2020年第4期8卷 371-376页

作者： Xin Yan wenwen jin Jie Zhang Mengke Wang Shousheng Liu Yongning Xin Department of Infectious Disease Qingdao Municipal HospitalQingdaoShandongChina Clinical Research Center Qingdao Municipal HospitalQingdaoShandongChina Digestive Disease Key Laboratory of Qingdao QingdaoShandongChina Dalian Medical University DalianLiaoningChina

Background and Aims:Coronary artery disease (CAD) is a major cause of morbidity and mortality in patients with non-alcoholic fatty liver disease (NAFLD). Previous studies have suggested that TCF7L2 rs7903146 was related to the risk of developing NAFLD but the conclusions are not consistent and no related study has been conducted in Chinese populations. The aim of this study was to investigate the association be-tween TCF7L2 rs7903146 and the risk of developing NAFLD and CAD in a Chinese Han population. Methods: TCF7L2 rs7903146 genotypes were measured by the MALDI-TOF-MS from 143 NAFLD patients, 159 CAD patients, 131 NAFLD+ CAD patients, and 212 healthy controls. The demographic data and serum lipid profiles of all subjects were collected. The distributions of genotype and allele frequency in each group were also tested. Logistic regression was used to inves-tigate the risk of TCF7L2 rs7903146 with NAFLD and CAD. All statistical analyses were conducted using SPSS 23.0. Results: There were no significant differences in the distri-butions of TCF7L2 rs7903146 genotype and allele frequency in each of the two groups, and the TCF7L2 rs7903146 CT+TT genotype did not increase the risk of developing NAFLD, CAD, and NAFLD+CAD. Except for body mass index in the control group, the differences of clinical parameters between the TCF7L2 rs7903146 T allele carriers and non-carriers in each group were not significant. In the non-obese group, the TCF7L2 rs7903146 CT+TT genotype was a protective factor for the development of NAFLD in the non-obese subjects (odds ratio=0.359, 95% confidence interval: 0.134-0.961, p = 0.041). Conclusions: TCF7L2 rs7903146 was not associated with the risk of developing NAFLD, CAD, and NAFLD + CAD in the Chinese Han population. In the non-obese population, the TCF7L2 rs7903146 CT + TT genotype was a protective factor against the development of NAFLD.

关键词： Nonalcoholic fatty liver disease Coronary artery disease TCF7L2 Single nucleotide polymorphism

Serum Resistin Levels in Adult Patients with Nonalcoholic Fatty Liver Disease:A Systematic Review and Meta-analysis

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Journal of Clinical and Translational Hepatology 2021年第4期9卷 484-493页

作者： Dongli Han Jie Chen Shousheng Liu Zengzhi Zhang Zhenzhen Zhao wenwen jin Yongning Xin Department of Infectious Disease Qingdao Municipal HospitalDalian Medical UniversityDalianLiaoningChina Qingdao City Shinan District Centers for Disease Control and Prevention QingdaoShandongChina Clinical Research Center Qingdao Municipal HospitalQingdaoShandongChina Digestive Disease Key Laboratory of Qingdao QingdaoShandongChina

Background and Aims:Previous studies reported that serum resistin levels were remarkably changed in patients with nonalcoholic fatty liver disease(NAFLD)but the conclusions were *** aim of this study was to investigate accurate serum resistin levels in adult patients with ***:A complete literature research was conducted in the PubMed,Embase,and Cochrane Library databases,and all the available studies up to 7 May 2020 were *** pooled standardized mean difference(SMD)values were calculated to investigate the serum resistin levels in patients with NAFLD and healthy ***:A total of 28 studies were included to investigate the serum resistin levels in patients with *** with NAFLD had higher serum resistin levels than controls(SMD=0.522,95%confidence interval[CI]:0.004–1.040,I2=95.9%).Patients with nonalcoholic steatohepatitis(NASH)had lower serum resistin levels than the healthy controls(SMD=−0.44,95%CI:−0.83–0.55,I2=74.5%).In addition,no significant difference of serum resistin levels was observed between patients with NAFL and healthy controls(SMD=−0.34,95%CI:−0.91–0.23,I2=79.6%)and between patients with NAFL and NASH(SMD=0.15,95%CI:−0.06–0.36,I2=0.00%).Furthermore,subgroup and sensitivity analyses suggested that heterogeneity did not affect the results of ***:This meta-analysis investigated the serum resistin levels in adult patients with NAFLD *** with NAFLD had higher serum resistin levels and patients with NASH had lower serum resistin levels than healthy *** resistin could serve as a potential biomarker to predict the development risk of NAFLD.

关键词： Resistin Nonalcoholic fatty liver disease Nonalcoholic steatohepatitis Biomarker

货币政策对民间借贷利率的作用机制与实施效果

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经济研究 2017年第8期52卷 78-93页

作者：潘彬金雯雯宁波大学商学院 315211 温州大学金融研究院 325035

本文试图从机会成本渠道、资产替代渠道、资产负债表渠道及逆向选择渠道对货币政策影响民间借贷利率的作用机制进行理论解释,论文运用回归分析模型与中介效应检验方法,以"宏观货币政策实施→信贷市场变化→民间借贷利率调整"为分析路径... 详细信息

本文试图从机会成本渠道、资产替代渠道、资产负债表渠道及逆向选择渠道对货币政策影响民间借贷利率的作用机制进行理论解释,论文运用回归分析模型与中介效应检验方法,以"宏观货币政策实施→信贷市场变化→民间借贷利率调整"为分析路径,实证考察我国货币政策对民间借贷利率的实施效果。研究发现,紧缩性的货币政策立场将引导民间借贷利率上行,价格型与数量型货币政策效果存在差异。与存款准备金政策有所不同,贷款基准利率调整未能显著影响民间借贷利率。进一步基于中介效应的检验结果表明,在货币政策立场对民间借贷利率的传导路径中,以信贷利率、信贷规模及银行风险承担为中介变量的中介效应显著,表明信贷市场通过机会成本渠道、资产替代渠道及逆向选择渠道发挥了显著的中介效应。

关键词：货币政策民间借贷利率中介效应

时变视角下非正规借贷利率的货币政策反应研究

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金融研究 2017年第10期 52-67页

作者：潘彬王去非金雯雯宁波大学商学院浙江宁波315211 中国人民银行杭州中心支行浙江杭州310001 温州大学金融研究院浙江温州325035

本文从时变视角研究了非正规借贷利率的货币政策反应,试图为二元金融结构下的货币政策选择提供参考。基于修正的IS-IM模型的研究表明,非正规借贷利率的货币政策反应受正规与非正规金融市场间的替代性等因素的影响。实证结果显示,非正规... 详细信息

本文从时变视角研究了非正规借贷利率的货币政策反应,试图为二元金融结构下的货币政策选择提供参考。基于修正的IS-IM模型的研究表明,非正规借贷利率的货币政策反应受正规与非正规金融市场间的替代性等因素的影响。实证结果显示,非正规借贷利率的货币政策反应具有明显的时变特征,表现在价格型货币政策工具在短期能够有效引导非正规借贷利率走势,但长期来看政策效果有所弱化;数量型货币政策工具在2008年国际金融危机前期出现暂时"失灵",但在后金融危机时期政策效果有明显改善。正规与非正规金融市场间替代性的动态演化能够为以上结论提供合理解释。本文研究还发现,正规与非正规金融市场利率间存在时变的同向变动关系,前者对后者的影响随滞后期数增加而衰减。

关键词：非正规借贷利率货币政策时变参数

国际资本流入动因:全球性、区域性还是异质性

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财经科学 2014年第10期 29-39页

作者：金雯雯杜亚斌郭永济南京大学商学院

基于43个国家金融与资本项目下贷方数据,利用动态分层因子模型将国际资本流入的波动来源分解为全球因子、区域因子与国家异质性成分,测算不同层级动因对国际资本流入的影响程度。研究结果表明,异质性因素作用最大,区域因素次之,最后是... 详细信息

基于43个国家金融与资本项目下贷方数据,利用动态分层因子模型将国际资本流入的波动来源分解为全球因子、区域因子与国家异质性成分,测算不同层级动因对国际资本流入的影响程度。研究结果表明,异质性因素作用最大,区域因素次之,最后是全球因素。此外,各层级因素的影响体现出资本结构、地区结构及经济体类型的差异性。从资本结构看,全球因素主要影响证券投资,异质性因素主要影响直接投资;从地区结构看,全球因素对欧元区经济体资本流入的影响最大,对亚洲及太平洋地区经济体资本流入的作用最小;从国家类型看,异质性因素对发达经济体资本流入的影响要小于对新兴经济体资本流入的影响,全球因子对两类经济体的影响程度则相反。

关键词：国际资本流入驱动因素全球性异质性

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供应链协同作用下我国邮轮旅游代理的发展

上海电力学院学报 2014年第S2期30卷 177-180页

作者：金雯雯上海电力学院科研处上海200090

基于供应链协同视角,分析了供应链协同对邮轮旅游代理的作用、影响邮轮旅游供应链协同关系的因素,以及供应链节点企业之间的协同关系。针对目前中国邮轮旅游代理存在的问题,提出了相应的对策。

关键词：供应链协同企业协同邮轮旅游代理

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硫酸法钛白粉还原过程的影响因素及机理研究

山西化工 2024年第11期44卷 159-160,182页

作者：靳雯雯龙佰集团股份有限公司河南焦作454150

研究硫酸法钛白粉生产水洗滤饼还原处理过程还原剂加入量、反应浓度、反应温度和反应pH值因素的影响作用。结果表明,增加还原剂铁粉加入量可有效降低Fe_(2)O_(3)含量,在0.12%~0.22%范围内,Fe_(2)O_(3)含量显著减少;反应原料浓度增加会导... 详细信息

研究硫酸法钛白粉生产水洗滤饼还原处理过程还原剂加入量、反应浓度、反应温度和反应pH值因素的影响作用。结果表明,增加还原剂铁粉加入量可有效降低Fe_(2)O_(3)含量,在0.12%~0.22%范围内,Fe_(2)O_(3)含量显著减少;反应原料浓度增加会导致Fe_(2)O_(3)含量升高,浓度过高会抑制还原效率;反应温度对还原效果具有显著影响,最佳反应温度为50℃;pH值对还原过程影响显著,较低pH值有利于Fe^(3+)向Fe^(2+)的转换。影响因素影响顺序为:反应pH值>还原剂加入量>反应温度>反应原料浓度。以上结果为实际生产中控制和优化硫酸法钛白粉的还原处理提供参考。

关键词：硫酸法钛白粉水洗滤饼还原过程

中国特色社会主义理论下的高校大学生思想政治教育工作分析

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文化创新比较研究 2020年第30期4卷 16-18页

作者：金雯雯台州学院医学院

改革开放以来,当代中国正经历着翻天覆地的巨变,中国特色社会主义事业正在蓬勃地发展,中国正以崭新的姿态走向全世界。在此关键的历史节点上,高校作为人才培养的重要阵地,中国特色社会主义理论指导下的高校大学生思想政治教育工作更是... 详细信息

改革开放以来,当代中国正经历着翻天覆地的巨变,中国特色社会主义事业正在蓬勃地发展,中国正以崭新的姿态走向全世界。在此关键的历史节点上,高校作为人才培养的重要阵地,中国特色社会主义理论指导下的高校大学生思想政治教育工作更是重中之重。结合弘扬中国特色社会主义核心价值观,坚定大学生社会主义理想信念,大学生思想政治教育工作与中国特色社会主义理论紧密结合,深入探讨当下高校大学生思想政治教育工作的现状,坚持将理论与实践相结合,提高思想政治理论课教学水平,全员、全过程、全方位地贯穿思想政治教育,是中国特色社会主义理论下的高校大学生思想政治教育工作的重要举措。

关键词：思想政治教育大学生中国特色社会主义高校