检索结果-南通市图书馆

Diffusion-weighted magnetic resonance imaging and micro-RNA in the diagnosis of hepatic fibrosis in chronic hepatitis C virus

引用

World Journal of Gastroenterology 2019年第11期25卷 1366-1377页

作者： tarek besheer Hatem Elalfy Mohamed Abd El-Maksoud Ahmed Abd El-Razek Saher Taman Khaled Zalata Wagdy Elkashef Hossam Zaghloul Heba Elshahawy Doaa Raafat Wafaa Elemshaty Eman Elsayed Abdel-Hady El-Gilany Mahmoud El-Bendary Department of Tropical Medicine and Hepatology Mansoura Faculty of Medicine-Mansoura University Department of Diagnostic Radiology Mansoura Faculty of Medicine-Mansoura University Department of Pathology Mansoura Faculty of Medicine-Mansoura University Department of Clinical Pathology Mansoura Faculty of Medicine-Mansoura University Department of Public Health and Preventive Medicine Mansoura Faculty of Medicine-Mansoura University

BACKGROUND Diffusion-weighted magnetic resonance imaging has shown promise in the detection and quantification of hepatic fibrosis. In addition, the liver has numerous endogenous micro-RNAs(miRs) that play important roles in the regulation of biological processes such as cell proliferation and hepatic *** To assess diffusion-weighted magnetic resonance imaging and miRs in diagnosing and staging hepatic fibrosis in patients with chronic hepatitis *** This prospective study included 208 patients and 82 age-and sex-matched controls who underwent diffusion-weighted magnetic resonance imaging of the abdomen, miR profiling, and liver biopsy. Pathological scoring was classified according to the METAVIR scoring system. The apparent diffusion coefficient (ADC) and miR were calculated and correlated with pathological *** The ADC value decreased significantly with the progression of fibrosis, from controls(F0) to patients with early fibrosis(F1 and F2) to those with late fibrosis(F3 and F4)(median 1.92, 1.53, and 1.25 × 10^(-3) mm^2/s, respectively)(P = 0.001).The cut-off ADC value used to differentiate patients from controls was 1.83 × 10^(-3) mm^2/s with an area under the curve(AUC) of 0.992. Combining ADC and miR-200 b revealed the highest AUC(0.995) for differentiating patients from controls with an accuracy of 96.9%. The cut-off ADC used to differentiate early fibrosis from late fibrosis was 1.54 × 10^(-3) mm^2/s with an AUC of 0.866. The combination of ADC and miR-200 b revealed the best AUC(0.925) for differentiating early fibrosis from late fibrosis with an accuracy of 80.2%. The ADC correlated with miR-200 b(r =-0.61, P = 0.001), miR-21(r =-0.62, P = 0.001), and miR-29(r = 0.52,P = 0.001).CONCLUSION Combining ADC and miRs offers an alternative surrogate non-invasive diagnostic tool for diagnosing and staging hepatic fibrosis in patients with chronic hepatitis C.

关键词： Diffusion Magnetic resonance imaging Fibrosis Liver Hepatitis C virus Micro-RNA

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Epidemiological Aspects of Intrafamilial Spread of HCV Infection in Egyptian Population: A Pilot Study

引用

Open Journal of Gastroenterology 2014年第5期4卷 228-236页

作者： Mahmoud El-Bendary Gamal Esmat Mustafa Neamatallah Emily Kamel tarek besheer Hatem Elalfy Maged El-Setouhy Dalia Omran Department of Community Environmental and Occupational Medicine Ain-Shams Faculty of Medicine Ain-Shams University Cairo Egypt Medical Biochemistry Department Mansoura Faculty of Medicine Mansoura University Mansoura Egypt Public Health & Preventive Medicine Department Mansoura Faculty of Medicine Mansoura University Mansoura Egypt Tropical Medicine & Hepatology Department Cairo Faculty of Medicine Cairo University Giza Egypt Tropical Medicine & Hepatology Department Mansoura Faculty of Medicine Mansoura University Mansoura Egypt

Aim: Liver disease is a leading cause of morbidity and mortality among Egyptians. The major cause is infection with HCV, with 70 000 up to 140 000 newly reported cases annually. The objectives of this study were to determine the prevalence of anti-HCV antibodies among household contacts of HCV index cases and to identify the possible risk factors of transmission of HCV among Egyptian families. Material and Methods: The present external pilot study (double centre study) was performed on a convenient sample of 125 index cases and their 321 household family contacts recruited from Mansoura & Cairo University where 2 questionnaires were used to collect data from the index & their related contacts. The all were exposed to clinical examinations, routine laboratory testing & screening for the prevalence of Anti-HCV antibodies. Results: The prevalence of anti-HCV seropositivity among household contacts of index cases was found to be 13.7% which husbands of female index cases ranked first followed by wives of male index cases (36.36% versus 17.86% respectively,

关键词： HCV Intrafamilial Transmission Epidemiology

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pathological characterization of occult hepatitis B virus infection in hepatitis C virus-associated or non-alcoholic steatohepatitis-related hepatocellular carcinoma

引用

World Journal of Meta-Analysis 2020年第2期8卷 67-77页

作者： Hatem Elalfy tarek besheer Dina Elhammady Ahmed El Mesery Shaker Wagih Shaltout Mohamed Abd El-Maksoud Ahmed I Amin Ahmed Nasr Bekhit Mahmoud Abd El Aziz Mahmoud El-Bendary Endemic Medicine Department Faculty of MedicineMansoura UniversityMansoura 35516Egypt Tropical Medicine Department Faculty of MedicinePort Said UniversityPort Said 42511Egypt Internal Medicine Department Faculty of MedicinePort Said UniversityPort Said 42511Egypt Tropical Medicine Department Zagazig General HospitalZagazig 44511Egypt

Occult hepatitis B virus(HBV)infection,by definition,is a state in which infection with this virus does not manifest with the conventional diagnostic laboratory criteria reserved for the obvious form of HBV *** a result,occult HBV infection is commonly a surprise finding discovered accidently during the evaluation of other apparent liver diseases,such as hepatitis C virus(HCV)infection or non-alcoholic fatty liver disease and,more importantly,their evolution into life-threatening hepatocellular *** infection with HCV and occult HBV is rarely considered when assessing these more obvious conditions,and in an attempt to offer a better understanding of this phenomenon,this study attempted to shed some light onto the uniqueness of occult HBV infection by addressing the natural history of HBV and HCV infections,as well as non-alcoholic fatty liver *** was carried out by taking into account the exclusive integration process undertaken by the HBV genome into infected host hepatocytes,with consideration given to conditions which afford reactivation of the occult infection and stress on the molecular mechanisms that underlie occult HBV ***,the clinical outcome of occult HBV infection and its relation to hepatocellular carcinoma is analyzed.

关键词： Occult hepatitis B virus Hepatitis C virus Non-alcoholic fatty liver disease Hepatocellular carcinoma Clinical outcome Pathophysiology of occult hepatitis B virus

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Experimental investigation of viscous oil-water-sand flow in horizontal pipes:Flow patterns and pressure gradient

引用

Petroleum 2024年第2期10卷 275-293页

作者： tarek Ganat Petroleum and Chemical Engineering Department Sultan Qaboos UniversityP.O.Box 50Muscat 123Sultanate of Oman

Fluid production from unconsolidated reservoirs often leads in sand production,which poses a number of *** deposition in flowlines can result in significant pressure dips,pipe and facility damage,and obstructions that decrease *** research is needed to understand the movement and deposition of sand in oil-water-sand(O-W-S) *** article focuses on O-W-S flows in a 6-meter-long horizontal pipe with an inner diameter of 0.0381 *** study looks at the flow behavior of high viscosity oil-water(O-W),water-sand(W-S),and oil-water-sand(O-W-S) *** were carried out at 250 psig pressure in a laboratory flow test facility using various heavy synthetic oils(viscosities ranging from 3500 cP to 7500 cP at 25℃) and tap *** sand concentration varied from 1% to 10%,with an average sand particle diameter of 145 μm and material density of 2630 kg/m~*** cuts ranged from 0.0 to *** experimental results revealed a minor change in pressure gradient between(O-W) and(O-W-S) ***,increasing the sand concentration in(O-W-S) flow resulted in higher pressure *** reduction factor of pressure gradient indicated that the highest decrease in pressure drop occurred at higher superficial oil ***,a direct relationship was observed between the reduction factor and the decrease in water *** results also showed that the minimum required transportation velocity for sand slurry decreased with increasing superficial oil velocity,while the minimum transportation condition increased with higher sand *** comparison between the expected pressure gradient from Bannwart and McKibben et *** the actual experimental data demonstrated significant accuracy for the oil viscosities and superficial oil velocities used in the study.

关键词： Slurry velocity Flow pattern Pressure gradient High viscosity Minimum transport condition

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Emerging applications of nanomaterials in chemical enhanced oil recovery:Progress and perspective

引用

Chinese Journal of Chemical Engineering 2020年第8期28卷 1995-2009页

作者： Najeebullah Lashari tarek Ganat Department of Petroleum Engineering Universiti Teknologi PETRONAS32610 Seri IskandarPerak Darul RidzuanMalaysia Department of Petroleum and Gas Engineering Dawood University of Engineering&TechnologyM.A Jinnah RoadKarachi-74800Pakistan

In enhanced oil recovery,different chemicalmethods utilization improves hydrocarbon recovery due to their fascinating abilities to alter some critical parameters in porous media,such as mobility control,the interaction between fluid to fluid,and fluid to rock *** decades the use of surfactant and polymer flooding has been used as tertiary recovery *** the current research,the inclusion of nanomaterials in enhanced oil recovery injection fluids solely or in the presence of other chemicals has got colossal *** emphasis of this review is on the applicability of nanofluids in the chemical enhanced oil *** responsiblemechanisms are an increment in the viscosity of injection fluid,decrement in oil viscosity,reduction in interfacial and surface tension,and alteration of wettability in the rock *** this review,important parameters are presented,which may affect the desired behavior of nanoparticles,and the drawbacks of nanofluid and polymer flooding and the need for a combination of nanoparticles with the polymer are *** to the lack of literature in defining the mechanism of nanofluid in a reservoir,this paper covers majorly all the previous work done on the application of nanoparticles in chemical enhanced oil recovery at home ***,the problems associatedwith the nano-enhanced oil recovery are outlined,and the research gap is identified,which must be addressed to implement polymeric nanofluids in chemical enhanced oil recovery.

关键词： Chemical enhanced oil recovery Mechanisms Nanoparticles Polymeric Nanofluids

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synthesized graphene oxide and fumed aerosil 380 dispersion stability and characterization with partially hydrolyzed polyacrylamide

引用

Chinese Journal of Chemical Engineering 2021年第6期34卷 307-322页

Hydrolyzed polyacrylamide(HPAM)is a commonly used polymer for the chemicals,mining and refining processes of hydrocarbon but suffers from a persistent high-temperature instability *** contrast,the nanoparticle suspension remains a technical challenge because of the strong interactions of van der Waal forces within nanoparticles,which always encourage *** research sought to improve nanoparticles(NP)stability and polymer(HPAM)rheological properties to improved hydrocarbon recovery by utilizing synthesized graphene oxide(GO)nanosheets and fumed Aerosil 380 Silica oxide(SiO_(2)).The aqueous nanocomposites based on HPAM-GO and HPAM-SiO_(2) in aqueous polymeric solutions have been developed,and its viscoelastic and static behaviour is *** results imply that by adding fumed silica NP,the viscoelastic behaviour of HPAM is marginally improved,particularly in high temperatures and salinity,however,the inclusion of GO's significantly improves the viscosity and stability of the base polymer fluid at high *** Fourier data for the transformation of the infrared spectrum confirmed that the hydrogen bonding formed between HPAM carbonyl groups and silica NP surface silanol functionality and covalent interlinking of electrostatic h-bonding between HPAM and functional GO contributed to the improved stabilization and improved rheological performance that helps to recover high salinity and temperature hydrocarbons.

关键词： Aggregation Composites Chemical enhance oil recovery Hydrocarbons Nanoparticles Polymer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Face Templates Encryption Technique Based on Random Projection and Deep Learning

引用

Computer Systems Science & Engineering 2023年第3期44卷 2049-2063页

作者： Mayada tarek Department of Computer Science Mansoura UniversityMansoura35516Egypt Department of Computer Science Jouf UniversityJouf2014KSA

Cancellable biometrics is the solution for the trade-off between two concepts:Biometrics for Security and Security for *** cancelable template is stored in the authentication system’s database rather than the original biometric *** case of the database is compromised,it is easy for the template to be canceled and regenerated from the same biometric *** of the cancelable template comes from the diversity of the cancelable transformation parameters(cancelable key).Therefore,the cancelable key must be secret to be used in the system authentication process as a second authentication factor in con-junction with the biometric *** main contribution of this paper is to tackle the risks of stolen/lost/shared cancelable keys by using biometric trait(in different feature domains)as the only authentication factor,in addition to achieving good performance with high *** standard Generative Adversarial Network(GAN)is proposed as an encryption tool that needs the cancelable key during the training phase,and the testing phase depends only on the biometric ***,random projection transformation is employed to increase the proposed system’s security and *** proposed transformation system is tested using the standard ORL face database,and the experiments are done by applying different features ***,a security analysis for the proposed transformation system is presented.

关键词： Cancelable biometrics(CBs) random projection ORL face database generative adversarial network(GAN)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

METHOD OF CENTERS ALGORITHM FORMULTI-OBJECTIVE PROGRAMMING PROBLEMS

引用

Acta Mathematica Scientia 2009年第5期29卷 1128-1142页

作者： tarek Emam Department of Mathematics Faculty of Science (Suez) Suez Canal University Suez Egypt

In this paper, we consider a method of centers for solving multi-objective programming problems, where the objective functions involved are concave functions and the set of feasible points is convex. The algorithm is defined so that the sub-problems that must be solved during its execution may be solved by finite-step procedures. Conditions are given under which the algorithm generates sequences of feasible points and constraint multiplier vectors that have accumulation points satisfying the KKT conditions. Finally, we establish convergence of the proposed method of centers algorithm for solving multiobjective programming problems.

关键词： method of centers multi-objective convergence approximated efficient solution

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

YKL-40 expression in human hepatocellular carcinoma:a potential biomarker?

引用

Hepatobiliary & Pancreatic Diseases International 2011年第6期10卷 605-610页

作者： tarek Hassanein Liver Center Hillcrest Medical CenterUniversity of California at San DiegoCA 92103USA

BACKGROUND:YKL-40 is a new biomarker with diagnostic value in many different *** it may serve as a biomarker for hepatocellular carcinoma (HCC) is still *** study aimed to examine the expression of YKL-40 in the serum and liver tissues of HCC patients and in HCC cell lines,in comparison with that in non-HCC liver disease patients and non-tumor hepatic cell lines,***:Immunohistochemical staining was used to detect YKL-40 protein expression in liver biopsy specimens from 8 HCC *** was used to assess the serum YKL-40 level in 90 HCC patients,90 inactive HBsAg carrier (IHC) patients with normal liver functions,and 90 liver cirrhosis ***-time PCR was used to determine the YKL-40 mRNA expression in three HCC cell lines and two non-tumor hepatic cell ***:Immunohistochemical staining of liver biopsy specimens from HCC patients showed that the YKL-40 protein expression in tumor tissue was higher than that in adjacent normal *** revealed that the YKL-40 serum level in the HCC group was significantly higher than that in the IHC group,but not significantly different from that in the cirrhosis ***-time PCR showed that YKL-40 mRNA levels in HCC cell lines were significantly higher than those in nontumor hepatic ***:YKL-40 is highly expressed in HCC at the molecular,cellular and tissue ***,it may not serve as a serum biomarker for HCC because measurement of the serum YKL-40 level cannot distinguish HCC from cirrhosis.

关键词： YKL-40 hepatocellular carcinoma cirrhosis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Overview of genetic causes of recurrent miscarriage and the diagnostic approach

引用

BIOCELL 2019年第4期43卷 253-262页

作者： tarek A ATIA Prince Sattam bin Abdulaziz University College of Applied Medical SciencesMedical Laboratory Sciences DepartmentAl-kharjSaudi Arabia

Recurring miscarriage(RM)is a frustrating reproductive complication with variable *** genetic defects have been known to play a crucial role in the etiology of *** abnormalities are frequently detected,while other genetic defects cannot be diagnosed through routine research,such as cryptic chromosomal anomalies,single nucleotide polymorphism,single-gene defect,and gene copy number *** laboratories have recently used variable advanced techniques to detect potential genetic abnormalities in couples with RM and/or in products of *** we aim to summarize the known genetic causes of RM,with a focus on the new diagnostic *** of the genetic profile of miscarriages is important for prognosis and potential counseling planning,as well as the prenatal diagnostic strategy in subsequent pregnancies.

关键词： Recurrent miscarriage Genetic defects Diagnostic approach Chromosomal microarray Next-generation sequencing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：