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Comparative evaluation of effect of injectable platelet-rich fibrin with collagen membrane compared with collagen membrane alone for gingival recession coverage

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World Journal of Experimental Medicine 2022年第4期12卷 68-91页

作者： Laxmikanta Patra subash chandra raj Neelima Katti Devapratim Mohanty Shib Shankar Pradhan Shaheda Tabassum Asit Kumar Mishra Kaushik Patnaik Annuroopa Mahapatra Department of Periodontics SCB Dental College and HospitalOdisha 753007India

BACKGROUND Collagen membrane and platelet-rich fibrin(PRF)have emerged as vital biomaterials in the field of periodontal *** invasive techniques are being preferred by most periodontists,as it is patient compliant with fewer post-surgical complications as compared to conventional surgical ***,in this study we have evaluated the effect of injectable PRF(i-PRF)with collagen membrane compared with collagen membrane alone using vestibular incision subperiosteal tunnel access(VISTA)technique for gingival recession *** To compare the efficacy of VISTA using collagen membrane with collagen membrane soaked in injectable PRF for gingival recession *** A split mouth randomized controlled clinical trial was designed;13 subjects having at least 2 teeth indicated for recession coverage were enrolled in this *** sites were randomly assigned to control group(VISTA using collagen membrane alone)and the test group(VISTA using collagen membrane with i-PRF).The clinical parameters assessed were pocket depth,recession depth(RD),recession width(RW),relative attachment level,keratinised tissue width(KTW),keratinised tissue thickness(KTT),and percentage root *** RD showed a statistically significant difference between the test group at 3 mo(0.5±0.513)and 6 mo(0.9±0.641)and the control group at 3 mo(0.95±0.51)and 6 mo(1.5±0.571),with P values of 0.008 and 0.04,*** also showed a statistically significant difference between the test group at 3 mo(1±1.026)and 6 mo(1.65±1.04)and the control group at 3 mo(1.85±0.875)and 6 mo(2.25±0.759),with P values of 0.008 and 0.001,*** for KTW showed statistically significant results between the test group at 1 mo(2.85±0.489),3 mo(3.5±0.513),and 6 mo(3.4±0.598)and the control group at 1 mo(2.45±0.605),3 mo(2.9±0.447),and 6 mo(2.75±0.444),with P values of 0.04,0.004,and 0.003,*** for KTT also showed statistically significant results between t

关键词： Vestibular incision subperiosteal tunnel access Injectable platelet-rich fibrin Collagen membrane Gingival recessions Treatment

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Navigating the hydrogen prospect:A comprehensive review of sustainable source-based production technologies, transport solutions,advanced storage mechanisms, and CCUS integration

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Journal of Energy Chemistry 2024年第10期97卷 166-215页

作者： Sehar Tasleem chandra Sekhar Bongu Mohan raj Krishnan Edreese Housni Alsharaeh College of Science and General Studies Alfaisal University

The review is a comprehensive discussion of current research advances,commercial scale developments,challenges,and techno-eco nomics for the entire H2value chain,including production,mainly focusing on sustainable sources,storage,and *** challenges,advantages,and uses of H2energy are included at ***,apart from the sustainable production approaches,the approaches and current developments for combating the carbon dioxide（CO2） emissions from existing H2production facilities are highlighted in terms of ca rbon capture,utilization,and storage（CCUS）.Concisely,the review discusses current material and recent technological adva ncements in developing pilot projects and large-scale establishments for viable and rapidly emerging sou rce-ba sed H2productio ***,the review also aims to provide an in-depthdiscussion and explore current developments based on the advantages of H2energy in terms of its utilization,based on its high energy density,and its ability to be used as a feedstock and *** the other hand,the challenges of H2are also elabo ***,the role of CCUS in a carbon-neutral economy and value chain for minimization of emissions from existing facilities is thoroughly deliberated,and the recent commercial-scale implementation of CCUS technologies is *** the utilization and recycling of captured CO2emissions along with H2to produce e-fuels in terms of current advances is detailed in this *** rthermore,the most applicable,efficient,a nd develo ping approaches are discussed for physical and chemical H2storage,considering recent la rge-scale implementations of liquid carriers and liquid organic hydrogen carriers as storage ***,the review elaborates on recent insights into advances in H2transport infrastructure,including compressed and liquid H2delivery via roads,ships,pipelines,and flight *** review gives precise insights into the recent scenario through an elaborated conclusion of each discussion t

关键词： Carbon capture E-fuels Hydrogen storage Hydrogen utilization Source-based hydrogen Transport infrastructure

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Correlation of neutrophil to lymphocyte ratio to severity of coronary artery disease and in-hospital clinical outcomes in patients with acute coronary syndrome: A prospective observational study

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Journal of Acute Disease 2024年第1期13卷 14-19页

作者： Vinodhkumar Kandibendla GThiruvikrama Prakash subash chandra Bose Prafull Dhewle Department of Cardiology Prakriya HospitalsNagasandraBangloreIndia Department of Cardiology E.S.HospitalVillupuramTamil NaduIndia Department of Cardiology Government Medical CollegeAnanthapuramuAndhra PradeshIndia Department of Cardiology Shrikrishna Hrudayalaya HospitalNagpurMaharashtraIndia

Objective:To explore correlation of neutrophil-to-lymphocyte ratio(NLR)to severity of coronary artery disease(CAD)and in-hospital clinical outcomes in patients with acute coronary syndrome(ACS).Methods:In this prospective and observational study,we recruited 500 patients with *** all the eligible patients,demographic details were collected,and laboratory parameters were *** CAD severity was evaluated in terms of the number of involved *** NLR was calculated based on neutrophils and lymphocytes and the correlation of various risk factors and severity and outcome of CAD was ***:77.2%of Patients was male,and 52%of the patients aged between 55-70 *** on the type of ACS,396 out of 500 patients had ST-elevation myocardial *** ascending trend in the white blood cell levels and NLR value was noted as the severity of the ACS increased and the highest white blood cell levels and NLR was noted among classⅣ*** mean NLR value among the non-survivors were higher compared to the survivors(9.52±5.72 vs.4.76±2.36;P<0.01).Receiver operating curve showed that the cut-off NLR value was 5.76 with a sensitivity of 75.0%and a specificity of 77.3%.Conclusions:The NLR can be used as an independent prognostic marker in *** elevated NLR value serves as a reliable predictor for short-term complications,notably in-hospital mortality.

关键词： Acute coronary syndrome Coronary artery disease Coronary vessels Hospital mortality Lymphocytes Neutrophils Prognosis Risk factors

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Influence of local stiffeners and cutout shapes on the vibration and stability characteristics of quasi-isotropic laminates under hygro-thermo-mechanical loadings

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Defence Technology（防务技术） 2022年第12期18卷 2107-2124页

作者： T.rajanna K.S.subash chandra K.Venkata Rao Department of Civil Engineering B.M.S College of EngineeringBengaluru560019India Research Scholar B.M.S College of EngineeringBengaluru560019India Department of Mechanical Engineering B.M.S Evening College of EngineeringBengaluru560019India Department of Mechanical Engineering Government PolytechnicBagepalli561207India

The perforated stiffened panel is generally found as a sub-component of sophisticated *** fundamental purpose of this panel is to withstand against buckling under complicated loading and environmental ***,an accurate knowledge of critical buckling behaviour of stiffened panels is very much essential for a reliable and lightweight structural *** this paper,the focus is on quasi-laminated panels with different cutout shapes of various sizes and their responses to hygrothermal environments under nonlinearly varying edge loads and is compared with the locally stiffened *** this,the modelling of the panel and stiffener is done by adopting nine-noded heterosis plate elements and three noded beam elements *** stiffener formulation is suitably modified in order to take the torsional effect also into consideration along with the effect of shear ***,the plate and the stiffener elements are treated separately,and then the displacement compatibility is maintained between them by using the transformation *** a given loading and geometric discontinuity,the stress distribution within the perforated panel is highly non-uniform in nature and hence a dynamic approach has been used to calculate buckling loads by adopting two sets of boundary conditions,one set for pre-buckling stress analysis and the second set for buckling *** different quasi-isotropic stacking sequences are deliberated in this work by varying different ply-orientation in each *** study also addresses the effect of various parameters such as nonlinear loads,hygro-thermal loads,cutout size and shapes,position of cutout,stiffener parameters,stacking sequences,thickness of plate and boundary conditions.

关键词： Locally stiffened panels Buckling Vibration Cutouts Heterosis Hygrothermal environment

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Distribution Pattern of Vascular Plant Species of Mountains in Nepal and their Fate Against Global Warming

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Journal of Mountain Science 2015年第6期12卷 1345-1354页

作者： Suresh chandra SUBEDI Khem raj BHATTARAI Ram Prasad CHAUUDHARY Earth and Environment Department Florida International University National Herbarium and Plant Laboratories Department of Plant Resources Ministry of Forest and Soil Conservation Research Center for Applied Science and Technology Tribhuvan University

This study aims to find the altitudinal distribution pattern of vascular plant species reported from high mountain of Nepal(Manang) along the whole Himalayan elevation gradient, and evaluate their fate against climate change. Data was gathered from multiple sources, field investigations, literatures, and herbarium specimens. Altogether, 303 vascular plant species were reported from Manang. We used a published data to calculate distribution range of each species by interpolating between its upper and lower elevation limits. The relationship between elevation and species richness is elucidated by generalized linear model. The consequence of global warming upon Manang's vascular plant species was estimated based on projected temperature change for next century and adiabatic lapse rate along the elevation gradient of the Himalayas. The vascular plant species richness has a unimodel relationship with elevation along the whole elevation gradient of Nepal as well as in three biogeographical regions of Nepal. Vascular plants of Manang are found distributed from low land Terai to high alpine regions of Nepal and their elevation distribution range varies from 200 to 4700 m. Out of 303 vascular plants of Manang, only seven species might be affected if temperature increase by 1.5°C, whereas at least 70 species will be affected with 5°C temperature increased. However, the majority of species(233 species) have wider distribution range(> 1000 m) and more than 5°C temperature tolerance range, thus they are likely to be less affected from global warming by the end of 21 st century.

关键词： Mountain Nepal Himalayas Elevation distribution range Global warming Temperature tolerance range Manang

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Hesperidin attenuates arsenic trioxide-induced cardiac toxicity in rats

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Asian Pacific Journal of Tropical Biomedicine 2023年第4期13卷 156-164页

作者： Gayatri Khuntia Jeevan Ranjan Dash Biswadeep Jena Uma Kanta Mishra subash chandra Parija Department of Pharmacology and Toxicology College of Veterinary Sciences and Animal HusbandryOUATBhubaneswarIndia Department of Veterinary Surgery and Radiology College of Veterinary Sciences and Animal HusbandryOUATBhubaneswarIndia Department of Veterinary Anatomy and Histology College of Veterinary Sciences and Animal HusbandryOUATBhubaneswarIndia

Objective:To explore the cardioprotective effect of hesperidin against arsenic trioxide-induced cardiac toxicity in ***:Cardiac toxicity was induced by oral administration of 4 mg/kg arsenic trioxide for 30 ***,biochemical,electrocardiography,echocardiography,and histopathological examinations were ***:Hesperidin decreased the neutrophil-to-lymphocyte ratio,calcium,creatine kinase-myoglobin binding,lactate dehydrogenase,IL-6,and lipid peroxidation,as well as increased sodium and potassium concentration and superoxide dismutase and catalase activity in arsenic trioxide-intoxicated ***,it reduced peak systolic velocity and end-diastolic velocity while increasing heart *** trioxide-induced histopathological damage to cardiac tissue was prominently alleviated by hesperidin ***:Hesperidin attenuates arsenic trioxide-induced cardiac toxicity in ***,it can be further explored as a cardioprotective agent.

关键词： Arsenic trioxide Hesperidin Cardiotoxicity ECG CK-MB LDH

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Biodiversity and Invasibility: Distribution Patterns of Invasive Plant Species in the Himalayas, Nepal

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Journal of Mountain Science 2014年第3期11卷 688-696页

作者： BHATTARAI Khem raj M?REN Inger Elisabeth SUBEDI Suresh chandra National Herbarium and Plant Laboratories Department of Plant Resources Department of Geography University of Bergen Department of Biological Science Florida International University

Invasive plant species are exerting a serious threat to biological diversity in many regions of the world. To understand plant invasions this study aims to test which of the two plant invasiveness hypotheses; ‘low native diversity' vs. ‘high native diversity', is supported by the regional distribution patterns of invasive plant species in the Himalayas,Nepal. This study is based on data retrieved from published literatures and herbarium specimens. The relationship between invasive plant species distribution patterns and that of native plant species is elucidated by scatter plots, as well as by generalized linear models. The native plant species and invasive plant species have similar distribution patterns and the maximum number of invasive plant species is found in the same altitudinal range where the highest richness for native tree species is found. There is a clear trend of higher invasive plant richness in regions where native tree species richness is relatively ***, the native plant richness is highest in the central phytogeographic region, followed by the eastern and the western regions, respectively. The invasive plant species also follows a similar ***, the invasive plant species richness was positively correlated with anthropogenic factors such as human population density and the number of visiting tourists. This study supports the hypothesis that ‘high native diversity' supports or facilitates invasive plant species. Further, it indicates that nativeand invasive plant species may require similar natural conditions, but that the invasive plant species seem more dependent and influenced by anthropogenic disturbance factors.

关键词： Anthropogenic disturbance Biodiversity Native species Biological invasions Distribution Himalayas

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Development and characterization of ethylcellulose based microsphere for sustained release of nifedipine

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Journal of Pharmaceutical Analysis 2016年第5期6卷 341-344页

作者： Patitapabana Parida subash chandra Mishra Subhashree Sahoo Ajit Behera Bibhukalyan Prasad Nayak Department of Biotechnology and Medical Engineering NIT Rourkela Odisha 769008 India Department of Metallurgical and Materials Engineering NIT Rourkela Odisha 769008 India Department of Pharmaceutics Kanakmanjari Institute of Pharmaceutical Sciences Rourkela Odisha 769015 India Department of Metallurgical and Materials Engineering IIT Kharagpur West Bengal 721302 India

This article introduced the work of ethylcellulose based polymeric microsphere loaded with nifedipine for reduction in frequency of administration with low solubility in aqueous medium and high rate of absorption in the stomach. The non-aqueous polymeric suspension was put dropwise into an aqueous medium containing polyvinyl alcohol as a surfactant for the synthesis of microsphere by solvent evaporation. The microspheres were characterized by different techniques, namely, XRD, SEM, and NMR. The formation of microspheres was confirmed by SEM. XRD analysis revealed the semi-crystallinity nature of microspheres. The NMR study indicated the presence of hetero-aromatic nucleus in the microsphere.

关键词： Nifedipine Microsphere Solvent evaporation Sustained release

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Growth and yield of Solanum khasianum in Pinus roxburghii forest based silvi-medicinal system in mid hills of Indian Himalaya

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Forest Ecosystems 2016年第4期3卷 320-328页

作者： chandra Shekher Sanwal raj Kumar Raheel Anwar Vijaysinha Kakade Sushma Kerketta S.D.Bhardwaj Indian Forest Service Uttarakhand Forest Department Haldwani Forest Division Haldwani 263139 Nainital Uttarakhand India ICAR-IISWC Research Center Vasad Anand 388306 Gujrat India Department of Forestry and Natural Resources Punjab Agricultural University Ludhiana 141 004 India Department of Silviculture and Agroforestry Dr. Y. S. Parrnar University of Horticulture and Forestry Nauni Solan 173 032 Himachal Pradesh India

Background：In mid hills of Western Himalayas,Himachal Pradesh India,growth,yield and economics of Solanum khasianum as a potential medicinal herb under Pinus roxburghii（Chir pine） plantation has been studied for two consecutive years to assess the performance of Solanum khasianum in undercanopy of Pinus roxburghii for developing Solanum khasianum and Pinus roxburghii based innovative silvi-medicinal ***：Growth parameters such as plant height,number of branches per plant and leaf area index followed by yield were estimated after Solanum khasianum was grown on three topographical aspects as;Northern,North- western and Western at a spacing of 45 cm x 45 cm,followed by three tillage depths as;minimum（0 cm）,medium（up to 10 cm）and deep tillage（up to 15 cm）,in open and below canopy conditions *** study was conducted to explore the possibility of using Solanum khasianum based silvi-medicinal system to utilize the below canopy of Chir pine forest for enhancing the productivity of forests besides the conservation of the medicinal ***：The growth parameters such as plant height,number of branches per plant and leaf area index were nonsignificantly affected by topographical aspects and tillage practices,both below canopy and open conditions except fresh weight and dry weight of berries during harvesting *** maximum yield（0.61 t·ha^（-1）） was observed on Western aspect in open conditions as compared to below canopy of Chir *** highest gross returns were observed for the crop cultivated on Western aspect under deep tillage in open conditions than other aspect and tillage *** the positive net returns from the crops raised in below canopy of Chir pine indicates its possible economic viability under agroforestry system as the gross returns was higher than the cost of ***：Solanum khasianum when grown in below canopy of Pinus roxburghii,its growth and yield indicated positive net *** khasianum and P

关键词： Bio-economic evaluation Silvi-medicinal system Inter-specific competition Topographical aspect Tillage depth Leaf area index(LAI)

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Ulipristal Acetate (UPA): An Alternative Option to Surgery for Uterine Fibroids in Reproductive Age: A Review

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Yangtze Medicine 2022年第1期6卷 1-11页

作者： subash chandra Sharma Cunjian Yi Department of Gynecology and Obstetrics The First Affiliated Hospital of Yangtze University Jinzhou China

Uterine fibroids are common in females of reproductive age and substantially affecting fertility and quality of life. Current management strategies mainly involve surgical interventions. For treatment, options available are surgical and non-surgical, but the mode of management leans on several factors, such as severity of symptoms, patient’s age, myoma characteristics, desire to preserve uterus and fertility. Alternative approach to surgery for the treatment of symptomatic females with uterine myomas has been recognized. Ulipristal acetate (UPA) has been the first selective progesterone-receptor modulator (SPRM) approved for the pre-operative and long-term management of uterine fibroids. There are evidences promoting an important role for progesterone pathways in the pathophysiology of uterine fibroids which supports the use of ulipristal acetate. The availability of alternative choices to surgical intervention is very necessary especially for those willing to preserve uterus and fertility. One of the alternatives is with ulipristal acetate, which has been proven to treat fibroid symptoms effectively.

关键词： Myoma Females Uterine Fibroids Selective Progesterone Receptor Modulator (SPRM) Ulipristal Acetate (UPA)

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