Comparative evaluation of effect of injectable platelet-rich fibrin with collagen membrane compared with collagen membrane alone for gingival recession coverage

作     者：Laxmikanta Patra Subash Chandra Raj Neelima Katti Devapratim Mohanty Shib Shankar Pradhan Shaheda Tabassum Asit Kumar Mishra Kaushik Patnaik Annuroopa Mahapatra 

作者机构：Department of PeriodonticsSCB Dental College and HospitalOdisha 753007India 

出 版 物：《World Journal of Experimental Medicine》 (世界实验医学杂志)

年 卷 期：2022年第12卷第4期

页      面：68-91页

学科分类：08[工学] 0812[工学-计算机科学与技术（可授工学、理学学位）] 

主　　题：Vestibular incision subperiosteal tunnel access Injectable platelet-rich fibrin Collagen membrane Gingival recessions Treatment 

摘      要：BACKGROUND Collagen membrane and platelet-rich fibrin(PRF)have emerged as vital biomaterials in the field of periodontal *** invasive techniques are being preferred by most periodontists,as it is patient compliant with fewer post-surgical complications as compared to conventional surgical ***,in this study we have evaluated the effect of injectable PRF(i-PRF)with collagen membrane compared with collagen membrane alone using vestibular incision subperiosteal tunnel access(VISTA)technique for gingival recession *** To compare the efficacy of VISTA using collagen membrane with collagen membrane soaked in injectable PRF for gingival recession *** A split mouth randomized controlled clinical trial was designed;13 subjects having at least 2 teeth indicated for recession coverage were enrolled in this *** sites were randomly assigned to control group(VISTA using collagen membrane alone)and the test group(VISTA using collagen membrane with i-PRF).The clinical parameters assessed were pocket depth,recession depth(RD),recession width(RW),relative attachment level,keratinised tissue width(KTW),keratinised tissue thickness(KTT),and percentage root *** RD showed a statistically significant difference between the test group at 3 mo(0.5±0.513)and 6 mo(0.9±0.641)and the control group at 3 mo(0.95±0.51)and 6 mo(1.5±0.571),with P values of 0.008 and 0.04,*** also showed a statistically significant difference between the test group at 3 mo(1±1.026)and 6 mo(1.65±1.04)and the control group at 3 mo(1.85±0.875)and 6 mo(2.25±0.759),with P values of 0.008 and 0.001,*** for KTW showed statistically significant results between the test group at 1 mo(2.85±0.489),3 mo(3.5±0.513),and 6 mo(3.4±0.598)and the control group at 1 mo(2.45±0.605),3 mo(2.9±0.447),and 6 mo(2.75±0.444),with P values of 0.04,0.004,and 0.003,*** for KTT also showed statistically significant results between t