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PhotoniX 2023年第1期4卷 382-392页

作者： Hojung Choi Joohoon Kim Wonjoong Kim Junhwa Seong Chanwoong Park Minseok Choi Nakhyun Kim Jisung Ha Cheng-Wei Qiu Junsuk rho Heon Lee Department of Materials Science and Engineering Korea UniversitySeoul 02841Republic of Korea Department of Mechanical Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Department of Electrical and Computer Engineering National University of SingaporeSingapore 117583Singapore Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea POSCO-POSTECH-RIST Convergence Research Center for Flat Optics and Metaphotonics Pohang 37673Republic of Korea National Institute of Nanomaterials Technology(NINT) Pohang 37673Republic of Korea ZERC Seoul 02841Republic of Korea

Nanoimprint lithography(NIL)has attracted attention recently as a promising fabrication method for dielectric metalenses owing to its low cost and high throughput,however,high aspect ratio(HAR)nanostructures are required to manipulate the full 2πphase of *** NIL using a hard-polydimethylsiloxane(h-PDMS)mold inevitably incurs shear stress on the nanostructures which is inversely proportional to the surface area parallel to the direction of ***,HAR structures are subjected to larger shear stresses,causing structural ***,we propose a novel wet etching NIL method with no detachment process to fabricate flawless HAR *** water-soluble replica mold is fabricated with polyvinyl alcohol(PVA)which is simpler than an h-PDMS mold,and the flexibility of the PVA mold is suitable for direct printing as its high tensile modulus allows high-resolution patterning of HAR *** diffraction-limited focusing of the printed metalenses demonstrates that it operates as an ideal lens in the visible *** method can potentially be used for manufacturing various nanophotonic devices that require HAR nanostructures at low cost and high throughput,facilitating commercialization.

关键词： Nanoimprint lithography Wet etching Polyvinyl alcohol High fidelity nanofabrication High aspect ratio nanostructure Metalens

Active pixel image sensor array for dual vision using large-area bilayer WS_(2)

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InfoMat 2024年第4期6卷 68-82页

作者： Arindam Bala Mayuri Sritharan Na Liu Muhammad Naqi Anamika Sen Gyuchull Han Hyun Yeol rho Youngki Yoon Sunkook Kim School of Advanced Materials Science and Engineering Sungkyunkwan UniversitySuwonRepublic of Korea Waterloo Institute for Nanotechnology(WIN) University of WaterlooWaterlooOntarioCanada Department of Electrical and Computer Engineering University of WaterlooWaterlooOntarioCanada

Transition metal dichalcogenides(TMDs)are a promising candidate for developing advanced sensors,particularly for day and night vision systems in vehicles,drones,and security *** traditional systems rely on separate sensors for different lighting conditions,TMDs can absorb light across a broad-spectrum *** this study,a dual vision active pixel image sensor array based on bilayer WS2 phototransistors was *** bilayer WS2 film was synthesized using a combined process of radio-frequency sputtering and chemical vapor *** WS2-based thin-film transistors(TFTs)exhibit high average mobility,excellent Ion/Ioff,and uniform electrical *** optoelectronic properties of the TFTs array exhibited consistent behavior and can detect visible to near-infrared light with the highest responsivity of 1821 A W1(at a wavelength of 405 nm)owing to the photogating ***,red,green,blue,and near-infrared image sensing capabilities of active pixel image sensor array utilizing light stencil projection were *** proposed image sensor array utilizing WS2 phototransistors has the potential to revolutionize the field of vision sensing,which could lead to a range of new opportunities in various applications,including night vision,pedestrian detection,various surveillance,and security systems.

关键词： dual vision image sensors infrared wavelength detection phototransistors thin-film transistor arrays transition metal dichalcogenides

Seasonal circulation in the southeastern Huanghai Sea

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Acta Oceanologica Sinica 1999年第3期18卷 375-388页

作者： Ig-Chan Pang(Department of Oceanography, Cheju National University, Cheju-do 690 - 756, Korea)Hong-Kil rho(Deppartment of Fishery, Cheju National University, Cheju-do 690 - 756, Korea)Jae-Hak Lee (Korea Ocean Research and Development Institute, Ansan, P. Department of Oceanography Cheju National University Cheju-do 690-756 South Korea Department of Fishery Cheju National University Cheju-do 690-756 South Korea Korea Ocean R. and D. Institute Ansan Seoul 425-600 P. O. Box 29 South Korea

The seasonal circulation in the southeastern Huanghai Sea has been studied with hydrographic data,which were observed in February and June 1994 and bimonthly during 1970 - 1990, and numerical model *** distributions of tempersture and salinity in 1994 are quite different due to strong tidal mixing so that weneed a analysis to see the real distributions of water masses. The mixing ratio analysis with the data of 1970 - 1990shows the connection of the waters in the west coasts of Korea Peninsula with warm and saline waters from the southin summer, which means northward inflows along the west coasts of Korea Peninsula in summer. With this flow, theseasonal circulations, which are deduced from the seasonal change of water mass distributions in the lower layer, arewarm inflows in winter and cold outflows in summer in the central Huanghai Sea, and cold outflows in winter andwarm inflows in summer along the west coasts of Korea Peninsula. The seasonall changed inflows might be theHuanghai Sea Warm Current. The monsoon winds can drive such circulations. However, summer monsoon winds areweak and irregular. As one of other possible dynamics, the variation of Kuroshio transport is numerically studied withallowing sea level fluctuations. Although it should be studied more, it possibly drives the summer circulations. The realcirculations seem to be driven by both of them.

关键词： Southeastern Huanghai Sea water mass analysis seasonal circulations Huanghai Sea Warm Current

Evaluation of anti-aging activities of various ginsenosides by typeⅠprocollagen synthesis and expression of MMP-1

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Evaluation of anti-aging activities of various ginsenosides ...

第八届中国化妆品学术研讨会

作者： Ho Sik rho Myung Hun Yeom Duck Hee Kim Han Gon Kim Jaeho Yeon Amore-Pacific R&D Center Korea Amore-Pacific Shanghai R&D Center China

Anti-aging activities of various ginsenosides were evaluated by typeⅠprocollagen synthesis and the expression of *** typeⅠprocollagen synthesis,Rb1,Rh2 and compound K were *** them, compound K was the most active *** typeⅠprocollagen,which was treated with compound K, was found to be 114.8%.In inhibition of MMP-1,Rb1,Rc,Rd and compound K were *** case of MMP-1 inhibition,compound K was also most active *** these results,we suggest that compound K may be used as a good candidate for the treatment of skin aging.

关键词： Anti-aging activity Ginsenosides TypeⅠprocollagen MMP-1

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用定量CT测定股骨颈的结构强度

医用生物力学 2000年第2期15卷 109-110页

作者：冯祖德 Jae rho Israel Ziv 美国纽约州立大学布法罗分校医学院骨科研究室厦门大学材料科学与工程系!厦门361005

髋部骨折是指发生在股骨颈和股骨粗隆部位的断裂.随着社会人口老龄化,对老年人髋部骨折的严重性已经引起世界范围内的高度关注.虽然大多数研究认为,髋部骨折是骨密度下降,即骨质疏松的结果,但是髋部骨结构的几何参数,如截面积,截面惯性... 详细信息

髋部骨折是指发生在股骨颈和股骨粗隆部位的断裂.随着社会人口老龄化,对老年人髋部骨折的严重性已经引起世界范围内的高度关注.虽然大多数研究认为,髋部骨折是骨密度下降,即骨质疏松的结果,但是髋部骨结构的几何参数,如截面积,截面惯性矩,骨质量的分布等等,也是决定骨结构强度的主要因素.本文的目的是利用模拟侧位跌倒时股骨近端受力模型,研究利用定量CT获得的股骨颈部位截面的骨密度、骨几何及其综合参数和股骨近端的断裂强度和吸收能之间的统计相关性,以提出一个预测老年性骨质疏松性髋部骨折的综合参数.

关键词：股骨颈结构强度抗弯刚度弯曲刚度骨密度骨质密度 CT

Modular operation of microfluidic chips for highly parallelized cell culture and liquid dosing via a fluidic circuit board

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Microsystems & Nanoengineering 2020年第1期6卷 106-121页

作者： A.R.Vollertsen D.de Boer S.Dekker B.A.M.Wesselink R.Haverkate H.S.rho R.J.Boom M.Skolimowski M.Blom R.Passier A.van den Berg A.D.van der Meer M.Odijk BIOS Lab on Chip Group MESA+Institute for NanotechnologyUniversity of TwenteEnschedeThe Netherlands Mesoscale Chemical Systems MESA+Institute for NanotechnologyUniversity of TwenteEnschedeThe Netherlands Institute for Technology-Inspired Regenerative Medicine Maastricht UniversityMaastrichtThe Netherlands Micronit Microtechnologies EnschedeThe Netherlands Applied Stem Cell Technologies TechMed CentreUniversity of TwenteEnschedeThe Netherlands

Microfluidic systems enable automated and highly parallelized cell culture with low volumes and defined liquid *** achieve this,systems typically integrate all functions into a single,monolithic device as a“one size fits all”***,this approach limits the end users’(re)design flexibility and complicates the addition of new functions to the *** address this challenge,we propose and demonstrate a modular and standardized plug-and-play fluidic circuit board(FCB)for operating microfluidic building blocks(MFBBs),whereby both the FCB and the MFBBs contain integrated valves.A single FCB can parallelize up to three MFBBs of the same design or operate MFBBs with entirely different *** operation of the MFBBs through the FCB is fully automated and does not incur the cost of an extra external *** use this modular platform to control three microfluidic large-scale integration(mLSI)MFBBs,each of which features 64 microchambers suitable for cell culturing with high spatiotemporal *** show as a proof of principle that we can culture human umbilical vein endothelial cells(HUVECs)for multiple days in the chambers of this ***,we also use the same FCB to control an MFBB for liquid dosing with a high dynamic *** results demonstrate that MFBBs with different designs can be controlled and combined on a single *** novel modular approach to operating an automated microfluidic system for parallelized cell culture will enable greater experimental flexibility and facilitate the cooperation of different chips from different labs.

关键词： FCB operation culture

Thalidomide effect in endothelial cell of acute radiation proctitis

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World Journal of Gastroenterology 2008年第30期14卷 4779-4783页

作者： Ki-Tae Kim Hiun-Suk Chae Jin-Soo Kim Hyung-Keun Kim Young-Seok Cho Whang Choi Kyu-Yong Choi Sang-Young rho Suk-Jin Kang Department of Radiology College of Medicine The Catholic University of Korea Uijeongbu St. Mary’s Hospital Department of Internal Medicine College of Medicine The Catholic University of Korea Uijeongbu St. Mary's Hospital Department of Internal Medicine College of Medicine The Catholic University of Korea Our Lady of Mercy Hospital Department of Internal Medicine College of Medicine The Catholic University of Korea Uijeongbu St. Mary’s Hospital Department of Pathology College of Medicine The Catholic University of Korea St. Vincent Hospital

AIM: To determine whether thalidomide prevents microvascular injury in acute radiation proctitis in white rats. METHODS: Fourteen female Wistar rats were used: six in the radiation group, six in the thalidomide group, and two in normal controls. The radiation and thalidomide groups were irradiated at the pelvic area using a single 30 Gy exposure. The thalidomide (150 mg/kg) was injected into the peritoneum for 7 d from the day of irradiation. All animals were sacrificed and the rectums were removed on day 8 after irradiation. The microvessels of resected specimens were immunohistochemically stained with thrombomodulin (TM), von Willebrand Factor (vWF), and vascular endothelial growth factor (VEGF). RESULTS: The microscopic scores did not differ significantly between the radiation and thalidomide groups, but both were higher than in the control group. Expression of TM was significantly lower inthe endothelial cells (EC) of the radiation group than in the control and thalidomide groups (P < 0.001). The number of capillaries expressing vWF in the EC was higher in the radiation group (15.3 ± 6.8) than in the control group (3.7 ± 1.7), and the number of capillaries expressing vWF was attenuated by thalidomide (10.8 ± 3.5, P < 0.001). The intensity of VEGF expression in capillaries was greater in the radiation group than in the control group and was also attenuated by thalidomide (P = 0.003). CONCLUSION: The mechanisms of acute radiation- induced proctitis in the rats are related to endothelial cell injury of microvessel, which may be attenuated with thalidomide.

关键词： Radiation proctitis Von Willebrand factor Thrombomodulin Vascular endothelial growth factor Thalidomide