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Evaluation of anti-aging activities of various ginsenosides ...

Evaluation of anti-aging activities of various ginsenosides by typeⅠprocollagen synthesis and expression of MMP-1

作     者:Ho Sik Rho Myung Hun Yeom Duck Hee Kim Han Gon Kim Jaeho Yeon 

作者单位:Amore-Pacific R&D CenterKorea Amore-Pacific Shanghai R&D CenterChina 

会议名称:《第八届中国化妆品学术研讨会》

会议日期:2010年

学科分类:081702[工学-化学工艺] 08[工学] 0817[工学-化学工程与技术] 

关 键 词:Anti-aging activity Ginsenosides TypeⅠprocollagen MMP-1 

摘      要:Anti-aging activities of various ginsenosides were evaluated by typeⅠprocollagen synthesis and the expression of *** typeⅠprocollagen synthesis,Rb1,Rh2 and compound K were *** them, compound K was the most active *** typeⅠprocollagen,which was treated with compound K, was found to be 114.8%.In inhibition of MMP-1,Rb1,Rc,Rd and compound K were *** case of MMP-1 inhibition,compound K was also most active *** these results,we suggest that compound K may be used as a good candidate for the treatment of skin aging.

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