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Effect of welding processes on mechanical and microstructural characteristics of high strength low alloy naval grade steel joints

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Defence Technology（防务技术） 2015年第3期11卷 308-317页

作者： s.RAGU NATHAN V.BALAsUBRAMANIAN s.MALARVIZHI A.G.RAO Department of Manufacturing Engineering Annamalai University Centre for Materials Joining & Research (CEMAJOR) Department of Manufacturing EngineeringAnnamalai University Naval Materials Research Laboratory (NMRL)

Naval grade high strength low alloy(HsLA) steels can be easily welded by all types of fusion welding processes. However, fusion welding of these steels leads to the problems such as cold cracking, residual stress, distortion and fatigue damage. These problems can be eliminated by solid state welding process such as friction stir welding(FsW). In this investigation, a comparative evaluation of mechanical(tensile, impact,hardness) properties and microstructural features of shielded metal arc(sMA), gas metal arc(GMA) and friction stir welded(FsW) naval grade HsLA steel joints was carried out. It was found that the use of FsW process eliminated the problems related to fusion welding processes and also resulted in the superior mechanical properties compared to GMA and sMA welded joints.

关键词：低合金高强度钢焊接工艺钢接头组织结构力学性能搅拌摩擦焊机械特性焊接方法

Quality of life issues in men undergoing androgen deprivation therapy： a review

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Asian Journal of Andrology 2012年第2期14卷 226-231页

作者： Rowan G Casey Niall M Corcoran s Larry Goldenberg University of British Columbia Department of Urologic sciences Vancouver General HospitalVancouverBC V5Z 1M9Canada

Androgen deprivation therapy （ADT） has been an essential treatment option for treating prostate cancer （PCa）. The role for hormonal treatment initially was restricted to men with metastatic and inoperable, locally advanced disease. Now it has been extended to neoadjuvant or adjuvant therapy for surgery and radiotherapy, for biochemical relapse after surgery or radiation, and even as primary therapy for non-metastatic disease. Fifty percent of PCa patients treated will receive ADT at some point. There is growing concern about the adverse effects and costs associated with more widespread ADT use. The adverse effects on quality of life （QoL）, including physical, social and psychological well-being when men are androgen-deprived, may be considerable. This review examines the QoL issues in the following areas： body feminisation, sexual changes, relationship changes, cognitive and affective symptoms, fatigue, sleep disturbance, depression and physical effects. Further suggestions for therapeutic approaches to reduce these alterations are suFuzested.

关键词： androgen deprivation therapy men prostate cancer quality of life

simultaneous scheduling of machines and automated guided vehicles in flexible manufacturing systems using genetic algorithms

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Journal of Central south University 2011年第5期18卷 1473-1486页

作者： I.A.Chaudhry s.Mahmood M.shami National University of sciences & Technology (NUsT) IslamabadPAKISTAN

The problem of simultaneous scheduling of machines and vehicles in flexible manufacturing system (FMs) was addressed.A spreadsheet based genetic algorithm (GA) approach was presented to solve the problem.A domain independent general purpose GA was used,which was an add-in to the spreadsheet *** adaptation of the propritary GA software was demonstrated to the problem of minimizing the total completion time or makespan for simultaneous scheduling of machines and vehicles in flexible manufacturing *** results are presented for a benchmark with 82 test problems,which have been constructed by other *** achieved results are comparable to the previous *** proposed approach can be also applied to other problems or objective functions without changing the GA routine or the spreadsheet model.

关键词： automated guided vehicles (AGVs) scheduling job-shop genetic algorithms flexible manufacturing system (FMs) spreadsheet

Detection and Classification of Diabetic Retinopathy Using DCNN and BsN Models

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Computers, Materials & Continua 2022年第7期72卷 597-609页

作者： s.sudha A.srinivasan T.Gayathri Devi Department of ECE SRCSASTRA Deemed UniversityKumbakonamIndia

Diabetes is associated with many complications that could lead to *** retinopathy,a complication of diabetes,is difficult to diagnose and may lead to vision *** identification of micro features in fundus images for the diagnosis of DR is a complex and challenging task for *** clinical testing involves complex procedures and is timeconsuming,an automated system would help ophthalmologists to detect DR and administer treatment in a timelymanner so that blindness can be *** research works have focused on image processing algorithms,or neural networks,or signal processing techniques alone to detect diabetic ***,we aimed to develop a novel integrated approach to increase the accuracy of *** approach utilized both convolutional neural networks and signal processing *** this proposed method,the biological electro retinogram(ERG)sensor network(BsN)and deep convolution neural network(DCNN)were developed to detect and classify *** the BsN system,electrodes were used to record ERGsignal,which was preprocessed to be *** was performed in the frequency domain by the application of fast Fourier transform(FFT)and mel frequency cepstral coefficients(MFCCs)were *** neural network(ANN)classifier was used to classify the signals of eyes with DR and normal ***,fundus images were captured using a fundus camera,and these were used as the input for DCNN-based *** DCNN consisted of many layers to facilitate the extraction of features and classification of fundus images into normal images,non-proliferative DR(NPDR)or earlystage DR images,and proliferative DR(PDR)or advanced-stage DR ***,it classifiedNPDRaccording tomicroaneurysms,hemorrhages,cotton wool spots,and exudates,and the presence of new blood vessels indicated *** accuracy,sensitivity,and specificity of the ANNclassifier were found to be 94%,95%,and 93%,***

关键词： Deep convolution neural network artificial neural network nonproliferative diabetic retinopathy biological ERG sensor network

Intestinal Kaposi's sarcoma may mimic gastrointestinal stromal tumor in HIV infection

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World Journal of Gastroenterology 2007年第33期13卷 4514-4516页

作者： A Zoufaly s schmiedel AW Lohse J van Lunzen Department of Medicine 1 University Medical Center Hamburg-Eppendorf Hamburg Germany Infectious Diseases Unit University Medical Center Hamburg-Eppendorf Hamburg Germany

Diffuse intestinal Kaposi＇s sarcoma shares macroscopic and histopathologic features with gastrointestinal stromal tumors. Correct diagnosis may pose a clinical challenge. We describe the case of a young HIV-1-infected African lady without advanced immunodeficiency, who presented with a diffuse spindle cell tumor of the gut. Initial diagnosis was of a gastrointestinal stromal tumor, based on endoscopy and histopathology. Further evaluation revealed evidence for human herpesvirus 8 （HHV8） and the diagnosis had to be changed to diffuse intestinal Kaposi＇s sarcoma. Antiretroviral triple therapy together with chemotherapy was commenced, and has led to the rapid remission of intestinal lesions. With a background of HIV infection, the presence of HHV8 as the causative agent of Kaposi＇s sarcoma should be determined, as distinct treatment is indicated.

关键词： Gastrointestinal stromal tumor Kaposi's sarcoma HIV infection Human herpesvirus 8 c-kit

Characterization of the Tomato Prosystemin Promoter:Organ-specific Expression,Hormone specificity and Methyl Jasmonate Responsiveness by Deletion Analysis in Transgenic Tobacco Plants

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Journal of Integrative Plant Biology 2012年第1期54卷 15-32页

作者： Hamlet Avilés-Arnaut John Paul Délano-Frier Center of Research and Advanced studies (Cinvestav) at Irapuato:Unit for Plant Biotechnology and Genetic Engineering

Tomato systemin is a bioactive peptide that regulates the systemic activation of wound-responsive genes. It is released from its 200 amino acid precursor called prosystemin. Initial tissue-localization and hormone-induced expression assays indicated that the tomato prosystemin gene （sIPs） accumulates mainly in floral tissues and in response to exogenous abscisic acid and methyl jasmonate （MeJA） treatments, respectively. Later, the promoter regions of the Ps gene in tomato （solanum lycopersicum L. cv. Castlemart）, pepper （Capsicum annuum） and potato （solanum tuberosum） were isolated and an in silico analysis of the sIPs promoter revealed an over-representation of stress- and MeJA-responsive motifs. A subsequent 5＇ deletion analysis of the sIPs promoter fused to the/^-glucuronidase reporter （GUs） gene showed that the -221 to ＋40 bp proximal sIPs promoter region was sufficient to direct the stigma, vascular bundle-specific and MeJA-responsive expression of GUs in transgenic tobacco plants. Important ***-specific, light- and MeJA-responsive cis-elements were also present in this region. These findings provide relevant information regarding the transcriptional regulation mechanisms of the sIPs promoter operating in transgenic tobacco plants. They also suggest that its Ussue-specificity and inducible nature could have wide applicability in plant biotechnology.

关键词： cis-regulatory elements flower specific jasmonic acid methyl jasmonate promoter analysis prosystemin wound-responsive genes.

Heat transfer and parametric studies of an encapsulated phase change material based cool thermal energy storage system

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Journal of Zhejiang University-science A(Applied Physics & Engineering) 2006年第11期7卷 1886-1895页

作者： CHERALATHAN M. VELRAJ R. RENGANARAYANAN s. school of Mechanical Engineering S.R.M. Engineering College SRM University Kattankulathur Chennai 603203 Tamilnadu India Institute for Energy studies Anna University Chennai 600025 India

This work investigates the transient behaviour of a phase change material based cool thermal energy storage (CTEs) system comprised of a cylindrical storage tank filled with encapsulated phase change materials (PCMs) in spherical container integrated with an ethylene glycol chiller plant. A simulation program was developed to evaluate the temperature histories of the heat transfer fluid (HTF) and the phase change material at any axial location during the charging period. The results of the model were validated by comparison with experimental results of temperature profiles of HTF and PCM. The model was also used to investigate the effect of porosity, stanton number, stefan number and Peclet number on CTEs system performance. The results showed that increase in porosity contributes to a higher rate of energy storage. However, for a given geometry and heat transfer coefficient, the mass of PCM charged in the unit decreases as the increase in porosity. The st number as well as the ste number is also influential in the performance of the unit. The model is a convenient and more suitable method to determine the heat transfer characteristics of CTEs system. The results reported are much useful for designing CTEs system.

关键词： Cool thermal energy storage (CTEs) Energy storage Freezing Phase change materials (PCMs) Heat transfer analysis Refrigeration

Evaluation of alternative conceptual models for groundwater modelling

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Geoscience Frontiers 2017年第3期8卷 437-443页

作者： Yangxiao Zhou H.M.P.s.D.Herath UNEsCO-IHE Institute for Water Education

This study evaluates the alternative conceptual models for groundwater modelling. A true model was created with a synthetic alluvial fan-plain hydrogeological framework. Various alternative conceptual models were evaluated for groundwater flow simulations. The first alternative model is a single aquifer layer model; the second alternative model is a 3-layer aquifer model; and the third model is a B-layer model consisting of 3 aquifers separated by 2 aquitards. All models could fit very well to the observa- tions with optimized values of hydraulic conductivities. However, the single aquifer layer model can only compute water balance components with good accuracy. The 3-layer aquifer model can be used for water balance computation and groundwater head simulation with small errors. The 5-layer model is capable of simulating water budget, groundwater head distribution and travel times with high accuracy. Multi- model analysis found only the 3rd alternative model superior.

关键词： Alternative conceptual modelsMulti-model analysisWater budgetTravel time

Platelet-rich plasma,an adjuvant biological therapy to assist peripheral nerve repair

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Neural Regeneration Research 2017年第1期12卷 47-52页

作者： Mikel sánchez Ane Garate Diego Delgado sabino Padilla Arthroscopic surgery Unit Hospital Vithas San JoseVitoria-GasteizSpain Department of Biomedical Engineering University of MinnesotaMinneapolisMNUSA BTI Biotechnology Institute Vitoria-GasteizSpain

Therapies such as direct tension-free microsurgical repair or transplantation of a nerve autograft,are nowadays used to treat traumatic peripheral nerve injuries（PNI）,focused on the enhancement of the intrinsic regenerative potential of injured ***,these therapies fail to recreate the suitable cellular and molecular microenvironment of peripheral nerve repair and in some cases,the functional recovery of nerve injuries is ***,new biomedical engineering strategies based on tissue engineering approaches through molecular intervention and scaffolding offer promising outcomes on the *** this sense,evidence is accumulating in both,preclinical and clinical settings,indicating that platelet-rich plasma products,and fibrin scaffold obtained from this technology,hold an important therapeutic potential as a neuroprotective,neurogenic and neuroinflammatory therapeutic modulator system,as well as enhancing the sensory and motor functional nerve muscle unit recovery.

关键词： peripheral nerve injuries(PNI) schwann cells axons platelet-rich plasma biomolecules fibrin scaffold intraneural perineural microenvironment