Intestinal Kaposi's sarcoma may mimic gastrointestinal stromal tumor in HIV infection
Intestinal Kaposi’s sarcoma may mimic gastrointestinal stromal tumor in HIV infection作者机构：Department of Medicine 1 University Medical Center Hamburg-Eppendorf Hamburg Germany Infectious Diseases Unit University Medical Center Hamburg-Eppendorf Hamburg Germany
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)
年 卷 期：2007年第13卷第33期
页 面：4514-4516页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Gastrointestinal stromal tumor Kaposi's sarcoma HIV infection Human herpesvirus 8 c-kit
摘 要：Diffuse intestinal Kaposi＇s sarcoma shares macroscopic and histopathologic features with gastrointestinal stromal tumors. Correct diagnosis may pose a clinical challenge. We describe the case of a young HIV-1-infected African lady without advanced immunodeficiency, who presented with a diffuse spindle cell tumor of the gut. Initial diagnosis was of a gastrointestinal stromal tumor, based on endoscopy and histopathology. Further evaluation revealed evidence for human herpesvirus 8 （HHV8） and the diagnosis had to be changed to diffuse intestinal Kaposi＇s sarcoma. Antiretroviral triple therapy together with chemotherapy was commenced, and has led to the rapid remission of intestinal lesions. With a background of HIV infection, the presence of HHV8 as the causative agent of Kaposi＇s sarcoma should be determined, as distinct treatment is indicated.
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