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Comparison of Surgical Techniques Used in Treating Acromioclavicular Dislocation in Patients Participating in Sports: A Systematic Review

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Open Journal of Orthopedics 2024年第1期14卷 41-52页

作者： Walter Hugo Brandão Nascimento Paulo Renan Matos Sucupira Cunha João Pedro Pimentel Abreu Lethycia Pereira rosa Kamilly Iêda Silva Veigas Rodrigo Martins Silva Caetano Orthopedic and Trauma Surgeon Brazilian Army Rio de Janeiro Brazil Orthopedic and Trauma Surgeon S&atildeo Luís Brazil Scholarship Holder National Council for Scientific and Technological Development (CNPq) S&atildeo Luís Brazil School of Medicine Federal University of Maranh&atildeo (UFMA) S&atildeo Luís Brazil Orthopedic and Trauma Surgeon Shoulder and Elbow Surgery Specialist University Hospital of the Federal University of Maranh&atildeo (HUUFMA/EBSERH) S&atildeo Luís Brazil

Introduction: The acromioclavicular joint is a superficial diarthrodial joint that surrounds the medial articular facet of the acromion and the distal portion of the clavicle. Due to its anatomy and biomechanics, it is highly susceptible to trauma and in young men who play contact sports, acromioclavicular dislocation is common. This article aimed to systematically review the literature and compare the surgical techniques used in the treatment of acromioclavicular dislocation in patients who practice sports. Methods: This systematic review was conducted according to the International Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines. Eligible studies for this systematic review included articles in English or Spanish published between 2013 and 2023, which mention the occurrence of acromioclavicular dislocation during sports practices. Additionally, only studies that addressed the surgical treatment of acromion-clavicular dislocation and contained original data on the topic were included. Results: We found 144 eligible studies after searching the LILACS and PubMed databases. Based on the inclusion and exclusion criteria and the reviewers’ consensus, we selected four studies for the systematic review. 133 patients with AC joint displacement were evaluated. Mean Age: approximately 31.90 years. 81.92 of these injuries occurred during sports practice. Surgical Procedures Used: titanium plates fixation (49 patients), arthroscopy (24), single tunnel technique (30) and coracoid sling technique (30). The results of the visual analog scale and Constant-Murley scores varied between the techniques used. Twenty-two complications after surgical treatment were identified. Conclusion: A significant variability of operative techniques can be used in the surgical approach of acromioclavicular dislocation, such as arthroscopy, single tunnel, coracoid sling and titanium plates. Although it presented excellent functional results compared to the other three tech

关键词： Acromioclavicular Joint Shoulder Dislocation Surgical Procedure Postoperative Complications Postoperative Care

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Concerns about the application of resistance exercise with blood-flow restriction and thrombosis risk in hemodialysis patients

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Journal of Sport and Health Science 2024年第4期13卷 548-558,F0003页

作者： Hugo de Luca Correa Lysleine Alves Deus Dahan da Cunha Nascimento Nicholas Rolnick Rodrigo Vanerson Passos Neves Andrea Lucena Reis Thais Branquinho de Araujo Carmen Tzanno-Martins Fernanda Silveira Tavares Luiz Sinesio Silva Neto Claudio Avelino Rodrigues Santos Paolo Lucas Rodrigues-Silva Fernando Honorato Souza Vitoria Marra da Motta Vilalva Mestrinho Rafael Lavarini dos Santos rosangela Vieira Andrade Jonato Prestes Thiago dos Santos rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance Mechanic Lehman CollegeNew YorkNY 10011USA Clinical Group Home Dialysis Center and RenalClass Sao Paulo 01239-040Brazil Department of Medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of Medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic Resources and Biotechnology Brasılia 70770-917Brazil Graduate Program of Genomic Sciences and Biotechnology Brasılia 71966-700Brazil

Background:Hemodialysis(HD) per se is a risk factor for *** the growing body of evidence on blood-flow restriction(BFR) exercise in HD patients,identification of possible risk factors related to the prothrombotic agent D-dimer is required for the safety and feasibility of this training *** aim of the present study was to identify risk factors associated with higher D-dimer levels and to determine the acute effect of resistance exercise(RE) with BFR on this ***:Two hundred and six HD patients volunteered for this study(all with a glomerular filtration rate of 70 years old),and HD ***,RE+BFR significantly increases D-dimer after 4 *** with borderline baseline D-dimer levels(400-490 ng/mL) displayed increased risk of elevating D-dimer over the normal range(≥500 ng/mL).Conclusion:These results identified factors associated with a heightened prothrombotic state and may assist in the screening process for HD patients who wish to undergo RE+BFR.D-dimer and/or other fibrinolysis factors should be assessed at baseline and throughout the protocol as a precautionary measure to maximize safety during RE+BFR.

关键词： Blood-flow restriction Chronic kidney disease Coagulation Hemodialysis Vascular occlusion exercises

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First evidence of heteroplasmy in Grey Partridge(Perdix perdix)

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Avian Research 2020年第3期11卷 363-365页

作者： Claudia Pizzirani Paolo Viola Federica Gabbianelli anna Fagotti Francesca Simoncelli Ines Di rosa Paolo Salvi Andrea Amici Livia Lucentini Department of Chemistry Biology and Biotechnologies(DCBB)University of Perugia06100 PerugiaItaly Department of Agriculture and Forest Science(DAFNE) University of Tuscia01100 ViterboItaly Department for Innovation in Biological Agro-food and Forest Systems(DIBAF) University of Tuscia01100 ViterboItaly Parco Nazionale dei Monti Sibillini 62039 VissoMCItaly

We report for the first time the occurrence of heteroplasmy in Grey Partridge(Perdix perdix)revealed by means of two mitochondrial *** possible serious biological and management implications of this exception to unila... 详细信息

关键词： Galliformes Grey Partridge Heteroplasmy Hybridization Perdix perdix

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The Iberian Roma Population Variant Server(IRPVS)

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Journal of Genetics and Genomics 2024年第7期51卷 769-773页

作者： Fabiola Mavillard Javier Perez-Florido Francisco M.Ortuño Amador Valladares Miren L.Álvarez-Villegas Gema Roldán rosario Carmona Manuel Soriano Santiago Susarte Pilar Fuentes Daniel López-López Ana María Nuñez-Negrillo Alejandra Carvajal Yolanda Morgado Daniel Arteaga rosa Ufano Pablo Mir Juan F.Gamella Joaquín Dopazo Carmen Paradas Macarena Cabrera-Serrano Instituto de Biomedicina de Sevilla(IBiS) Hospital Universitario Virgen del Rocío/CSIC/Universidad de SevillaSevillaSpain Centro Investigación Biomédica en Red Enfermedades Neurodegenerativas(CIBERNED) Instituto de Salud CarlosⅢSevillaSpain Plataforma Andaluza de Medicina Computacional Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevillaSpain Grupo de medicina computacional de sistemas Instituto de Biomedicina de Sevilla(IBiS)Hospital Virgen del RocíoSevillaSpain Nodo de Genómica Funcional (INB-ELIXIR-es)Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevilla 41013Spain Bioinformática en Enfermedades raras(BiER) Centro de Investigación Biomédica en Red de Enfermedades Raras(CIBERER)Instituto de salud CarlosⅢSevillaSpain Departamento de Ingeniería de Computadores Automática y RobóticaUniversidad de GranadaGranadaSpain Servicio de Urgencias de Atención Primaria Distrito SevillaSevillaSpain Centro de Servicios Sociales Negociado de Servicios EspecializadosAyuntamiento de SevillaSevillaSpain Departamento de Enfermería Facultad de Ciencias de la SaludUniversidad de GranadaGranadaSpain Departamento de Neurología Hospital Virgen de las NievesGranadaSpain Departamento de Neurología Hospital Virgen de ValmeSevillaSpain Centro de Salud Utrera Sur SevillaSpain Centro de Salud Polígono Sur SevillaSpain Unidad de Trastornos del Movimiento Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain Departamento de Medicina Facultad de MedicinaUniversidad de SevillaSevilleSpain Departamento de Antropología Social Universidad de GranadaSpain Unidad Enfermedades Neuromusculares Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain

In recent years,the number of known disease genes has exponentially grown due to the widespread adoption of cost-effective massive parallel *** identify new disease variants,especially in monogenic disorders,a frequen... 详细信息

关键词： Server filtering massive

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Atmospheric and ecosystem big data providing key contributions in reaching United Nations’Sustainable Development Goals

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Big Earth Data 2021年第3期5卷 277-305页

作者： Markku Kulmala anna Lintunen Ilona Ylivinkka Janne Mukkala rosa Rantanen Joni Kujansuu Tuukka Petäjä Hanna K.Lappalainen Institute for Atmospheric and Earth System Research(INAR)/Physics Faculty of ScienceUniversity of HelsinkiFinland Joint International Research Laboratory of Atmospheric and Earth System Sciences School of Atmospheric SciencesNanjing UniversityNanjingChina Aerosol and Haze Laboratory Beijing Advanced Innovation Center for Soft Matter Sciences and EngineeringBeijing University of Chemical Technology(BUCT)BeijingChina Faculty of Geography Lomonosov Moscow State UniversityMoscowRussia Tyumen State University Department of CryosphereTyumenRussia fGuangzhou Institute of Geography Guangzhou Academy of SciencesGuangzhouChina Institute for Atmospheric and Earth System Research University of Helsinki Finland Aerospace Information Research Institute Chinese Academy of SciencesBeijingChina

Big open data comprising comprehensive,long-term atmospheric and ecosystem in-situ observations will give us tools to meet global grand challenges and to contribute towards sustainable *** Nations’Sustainable Development Goals(UN SDGs)provide framework for the *** present synthesis on how Station for Measuring Earth Surface-Atmosphere Relations(SMEAR)observation network can contribute to UN *** describe SMEAR II flagship station in Hyytiälä,*** more than 1200 variables measured in an integrated manner,we can under-stand interactions and feedbacks between biosphere and *** contributes towards understanding impacts of climate change to natural ecosystems and feedbacks from ecosys-tems to *** benefits of SMEAR concept are highlighted through outreach project in Eastern Lapland utilizing SMEAR I observations from Värriöresearch *** contrast to boreal environment,SMEAR concept was also deployed in *** underline the benefits of comprehensive observations to gain novel insights into complex interactions between densely popu-lated urban environment and *** observations enable work towards solving air quality problems and improve the quality of life inside *** network of comprehensive stations with various measurements will enable science-based deci-sion making and support sustainable development by providing long-term view on spatio-temporal trends on atmospheric compo-sition and ecosystem parameters.

关键词： Grand challenges in-situ observations big open data SMEAR concept SDGs

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Relationship between nonalcoholic fatty liver disease and chronic kidney disease could start in childhood

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World Journal of Gastroenterology 2021年第34期27卷 5793-5795页

作者： anna Di Sessa Stefano Guarino rosa Melone Rossella Francesca De Simone Pierluigi Marzuillo Emanuele Miraglia del Giudice Department of Woman Childand General and Specialized SurgeryUniversity of Campania Luigi VanvitelliNaples 80138Italy

The relationship between nonalcoholic fatty liver disease(NAFLD)and chronic kidney disease(CKD)has gained considerable scientific interest in adults over the past few ***,this association has recently emerged in *** published studies have suggested a role for NAFLD as a risk factor for CKD from the earliest age,with a potential influence of the major NAFLD risk polymorphisms,resulting in an increased risk of both cardiovascular and metabolic *** view of the progressive course and increased cardiometabolic risk closely related to NAFLD and CKD,we focused on the link between these diseases in childhood.

关键词： Nonalcoholic fatty liver disease Chronic kidney disease Children Liver

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Replication of interleukin 23 receptor and autophagy-related 16-like 1 association in adult-and pediatric-onset inflammatory bowel disease in Italy

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World Journal of Gastroenterology 2008年第29期14卷 4643-4651页

作者： anna Latiano Orazio Palmieri Maria rosa Valvano Renata D'Incà Salvatore Cucchiara Gabriele Riegler anna Maria Staiano Sandro Ardizzone Salvatore Accomando Gian Luigi de Angelis Giuseppe Corritore Fabrizio Bossa Vito Annese U.U. O.O. di Gastroenterologia ed Endoscopia Ospedale IRCCS-CSSSan Giovanni Rotondo (Fg) 71013 Italy Cattedra di Gastroenterologia Università di PadovaPadova 35122 Italy Clinica Pediatrica Università "La Sapienza" Roma 00185 Italy Cattedra di Gastroenterologia Università di NapoliNapoli 80131 Italy Clinica Pediatrica Università di Napoli Napoli 80131 Italy Unità di Gastroenterologia Ospedale "Sacco" Milano 20157 Italy Clinica Pediatrica Università di Palermo Palermo 90128 Italy Clinica Pediatrica Università di Parma Parma 43100 Italy

AIM: To investigate gene variants in a large Italian inflammatory bowel disease (IBD) cohort, and to analyze the correlation of sub-phenotypes (including age at diagnosis) and epistatic interaction with other IBD genes. METHODS: Total of 763 patients with Crohn's disease (CD, 189 diagnosed at age < 19 years), 843 with ulcerative colitis (UC, 179 diagnosed <19 years), 749 healthy controls, and 546 healthy parents (273 trios) were included in the study. The rs2241880 [autophagy-related 16-like 1 (ATG16L1)], rs11209026 and rs7517847 [interleukin 23 receptor (IL23R)], rs2066844, rs2066845, rs2066847 (CARD15), rs1050152 (OCTN1), and rs2631367 (OCTN2) gene variants were genotyped. RESULTS: The frequency of G allele of ATG16L1 SNP (Ala197Thr) was increased in patients with CD compared with controls (59% vs 54% respectively) (OR = 1.25, CI = 1.08-1.45, P = 0.003), but not in UC (55%). The frequency of A and G (minor) alleles of Arg381Gln, rs11209026 and rs7517847 variants of IL23R were reduced significantly in CD (4%, OR = 0.62, CI = 0.45-0.87, P = 0.005; 28%, OR = 0.64, CI = 0.55-0.75, P < 0.01), compared with controls (6% and 38%, respectively). The A allele (but not G) was also reduced signifi cantly in UC (4%, OR = 0.69, CI = 0.5-0.94, P = 0.019). No association was demonstrated with sub-phenotypes and interaction with CARD15 , and OCTN1/2 genes, although both gene variants were associated with pediatric-onset disease. CONCLUSION: The present study confirms the association of IL23R polymorphisms with IBD, and ATG16L1 with CD, in both adult- and pediatric-onset subsets in our study population.

关键词： Inflammatory bowel disease Crohn'sdisease Ulcerative colitis Genetic predisposition Autophagy-related 16-like 1 Interleukin 23 receptor Genome-wide association study Pediatric inflammatorybowel disease

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Chronic hepatitis C virus infection and atherosclerosis: Clinical impact and mechanisms

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World Journal of Gastroenterology 2014年第13期20卷 3410-3417页

作者： Luigi E Adinolfi rosa Zampino Luciano Restivo Amedeo Lonardo Barbara Guerrera Aldo Marrone Fabio Nascimbeni anna Florio Paola Loria Department of Medical SurgicalNeurologicalMetabolicand Geriatric SciencesSecond University of Naples80100 NaplesItaly Department of Internal Medicine EndocrinologyMetabolism and GeriatricsUniversity of Modena and Reggio Emilia41126 Modena Italy Vascular Surgery Second University of Naples80100 NaplesItaly

Hepatitis C virus(HCV)infection represents a major health issue worldwide due to its burden of chronic liver disease and extrahepatic manifestations including cardiovascular diseases,which are associated with excess *** of published studies supports the view that HCV infection should be considered a risk factor for the development of carotid atherosclerosis,heart failure and *** contrast,findings from studies addressing coronary artery disease and HCV have yielded conflicting ***,meta-analytic reviews and prospective studies are *** pathogenic mechanisms connecting HCV infection,chronic liver disease,and atherogenesis are not completely ***,it has been hypothesized that HCV may promote atherogenesis and its complications through several direct and indirect biological mechanisms involving HCV colonization and replication within arterial walls,liver steatosis and fibrosis,enhanced and imbalanced secretion of inflammatory cytokines,oxidative stress,endotoxemia,mixed cryoglobulinemia,perturbed cellular and humoral immunity,hyperhomocysteinemia,hypo-adiponectinaemia,insulin resistance,type 2 diabetes and other components of the metabolic *** these complex mechanisms is of fundamental importance for the development of novel therapeutic approaches to prevent and to treat vascular complications in patients with chronic HCV ***,it seems that HCV clearance by interferon and ribavirin treatment significantly reduces non-liver-related mortality;moreover,interferon-based treatment appears to decrease the risk of ischemic stroke.

关键词： Hepatitis C virus Atherosclerosis Coronary artery disease Stroke Inflammation

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In vitro Metabolomic Approaches to Investigating the Potential Biological Effects of Phenolic Compounds:An Update

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Genomics, Proteomics & Bioinformatics 2017年第4期15卷 236-245页

作者： Ursula Catalan Laura Barrubes rosa Maria Vails rosa Soila Laura Rubio Functional Nutrition Oxidation and Cardiovascular Diseases Group(NFOC-Salut)Technological Center of Nutrition and Health(CTNS)lnstitut d'lnvestigacio Sanitaria Pere Virgili(IISPV)Faculty of Medicine and ttealth SciencesUniversitat Rovira i VirgiliReus 43201Spain Food Technology Department Universitat de Lleida-AGROTECNIO CenterLleida 25198Spain

Dietary phenolic compounds （PCs） have been receiving intercst lor their presumcd roles ill disease prevention. However, there is a lack of studies on the underlying molecular mechanisnls. In this regard, in vitro metabolomic approaches are suitable for the investigation o1 the molecular changes in response to PC exposure. Up to date, the biological effects of PCs have only been cxalnined for PCs from rosemary （Rosmarinus officinalis）, olive oil, and reSVCl-atrol using cell-based mctabolomic approach, although transcriptomic and/or proteomic studies have also been conducted in the same in vi[ro cell experiment in some cases. Our integral analysis of the reviewed studies suggest that PCs may be involved not only in basic cellular processes or macro-and micro-nutrient meta- bolism, but also in specific metabolic pathways that have been thoroughly investigated. These modulated pathways could have a clinical impact on neurodegenerativc diseases, type 2 diabetes, cancer, and cardiovascular diseases. In conclusion, the in vitro metabolomic approaches provide additional information of the molecular mechanisms involved in disease risk reduction of dietary PCs. In order to elucidate the mechanisms of action of PCs, more metabolomic cell-based studies are nccdcd and testing the physiological conjugated forms of PCs in these cell systems could be of special interest.

关键词： Cell-based Metabolomics Phenolic compounds Mechanism of action Disease prevention

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Analysis of hydrodynamic effects on biofilm thickness in fluidized-bed tapered bioreactors

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Particuology 2021年第5期19卷 48-57页

作者： Daniela Maria Koerich Leonardo Machado da rosa Chemical Engineering Department University of Blumenau(FURB)3250 Sao Paulo Street89030-000 BlumenauSanta CatarinaBrazil

Fluidized beds in tapered geometries provide advantages such as a broad range of optimum operating ***,the dynamics of the flow inside these bioreactors is significantly more complex,as they promote non-uniform bioparticles *** this end,the CFD technique can give a detailed description of the flow in the ***,the aim of this work is to assess the influence of the hydrodynamic on the steady-state biofilm thickness through numerical simulations of liquid–solid fluidized *** geometries of tapered bioreactors in the operating conditions used to develop *** were run to solve the two-phase RANS equations using the open-source software OpenFOAM in *** SST k−ω model was used to estimate the turbulent features of the *** and bioparticles distribution inside the reactor were analyzed for different inlet velocities,while bioparticles collision frequency and shear stresses were evaluated for various operating *** comparison between the turbulent kinetic energy and the granular temperature indicated that the fluid flow is more turbulent than the bioparticles *** hydrodynamics influence on the steady-state biofilm thickness was assessed,and results led to the conclusion that biofilm is more sensitive to hydrodynamic shear stress than bioparticles collisions.

关键词： Liquid-solid fluidization Shear stress Particles collisions Computational fluid dynamics Biofilm Tapered bioreactors

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