Concerns about the application of resistance exercise with blood-flow restriction and thrombosis risk in hemodialysis patients

作     者：Hugo de Luca Correa Lysleine Alves Deus Dahan da Cunha Nascimento Nicholas Rolnick Rodrigo Vanerson Passos Neves Andrea Lucena Reis Thais Branquinho de Araujo Carmen Tzanno-Martins Fernanda Silveira Tavares Luiz Sinesio Silva Neto Claudio Avelino Rodrigues Santos Paolo Lucas Rodrigues-Silva Fernando Honorato Souza Vitoria Marra da Motta Vilalva Mestrinho Rafael Lavarini dos Santos Rosangela Vieira Andrade Jonato Prestes Thiago dos Santos Rosa Hugo de Luca Corrêa;Lysleine Alves Deus;Dahan da Cunha Nascimento;Nicholas Rolnick;Rodrigo Vanerson Passos Neves;Andrea Lucena Reis;Thais Branquinho de Araújo;Carmen Tzanno-Martins;Fernanda Silveira Tavares;Luiz Sinésio Silva Neto;Cláudio Avelino Rodrigues Santos;Paolo Lucas Rodrigues-Silva;Fernando Honorato Souza;Vitória Marra da Motta Vilalva Mestrinho;Rafael Lavarini dos Santos;Rosangela Vieira Andrade;Jonato Prestes;Thiago dos Santos Rosa

作者机构：Post-graduate Program of Physical EducationCatholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance MechanicLehman CollegeNew YorkNY 10011USA Clinical Group Home Dialysis Center and RenalClassSao Paulo 01239-040Brazil Department of MedicineCatholic University of BrasıliaBrasılia 71966-700Brazil Faculty of MedicineFederal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic Resources and BiotechnologyBrasılia 70770-917Brazil Graduate Program of Genomic Sciences and BiotechnologyBrasılia 71966-700Brazil 

出 版 物：《Journal of Sport and Health Science》 (运动与健康科学（英文）)

年 卷 期：2024年第13卷第4期

页      面：548-558,F0003页

核心收录：

学科分类：0403[教育学-体育学] 040302[教育学-运动人体科学(可授教育学、理学、医学学位)] 04[教育学] 1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：supported by a grant provided by the Coordenacao de Aperfeicoamento de Pessoal de Nível Superior-Brazil-Finance Code 001 and National Council for Scientific and Technological Development financed in part by the Conselho Nacional de Desenvolvimento Científico e Tecnológico and Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior-Brasil--Finance Code 001 funded by the Fundacao de Apoio à Pesquisa do Distrito Federal with grants from demanda espontanea-Edital 09/2022 

主　　题：Blood-flow restriction Chronic kidney disease Coagulation Hemodialysis Vascular occlusion exercises 

摘      要：Background:Hemodialysis(HD) per se is a risk factor for *** the growing body of evidence on blood-flow restriction(BFR) exercise in HD patients,identification of possible risk factors related to the prothrombotic agent D-dimer is required for the safety and feasibility of this training *** aim of the present study was to identify risk factors associated with higher D-dimer levels and to determine the acute effect of resistance exercise(RE) with BFR on this ***:Two hundred and six HD patients volunteered for this study(all with a glomerular filtration rate of 70 years old),and HD ***,RE+BFR significantly increases D-dimer after 4 *** with borderline baseline D-dimer levels(400-490 ng/mL) displayed increased risk of elevating D-dimer over the normal range(≥500 ng/mL).Conclusion:These results identified factors associated with a heightened prothrombotic state and may assist in the screening process for HD patients who wish to undergo RE+BFR.D-dimer and/or other fibrinolysis factors should be assessed at baseline and throughout the protocol as a precautionary measure to maximize safety during RE+BFR.