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A Ferrocenylsulfide-mediated Sulfur Ylide Epoxidation Reaction

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Chinese Chemical Letters 2005年第7期16卷 853-855页

作者： leiwang ZhiZhenHUANG DepartmentofChemistry ZhejiangUniversityHangzhou310027

A ferrocenylsulfides 1-2 mediated sulfur ylide epoxidation reaction was found to stereoselectively afford trans-oxiranes in excellent yields with recoverable starting material.

关键词： Ferrocenylsulfide epoxidation stereoselectivity oxiranes sulfur ylide.

Provisioning QoS Guarantee by Multipath Routing and Reservation in Ad Hoc Networks

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Journal of Computer Science & Technology 2004年第2期19卷 128-137页

作者： Yan-TaiShu Guang-HongWang leiwang OliverW.W.Yang Yong-JieFan DepartmentofComputerScience TianjinUniversityTianjin300072P.R.China BellLabsResearchChina Beijing100080P.R.China SchoolofInformationTechnologyandEngineering UniversityofOttawaOttawaOntarioKIN6N5Canada

In this paper, a QoS multipath source routing protocol (QoS-MSR) is proposedfor ad hoc networks. It can collect QoS information through route discovery mechanism of multipathsource routing (MSR) and establish QoS route with reserved bandwidth. In order to reserve bandwidthefficiently, a bandwidth reservation approach called the multipath bandwidth splitting reservation(MBSR) is presented, under which the overall bandwidth request is split into several smallerbandwidth requests among multiple paths. In simulations, the authors introduce Insignia, an in-bindsignaling system that supports QoS in ad hoc networks, and extend it to multipath Insignia(M-Insignia) with QoS-MSR and MBSR. The results show that QoS-MSR routing protocol with the MBSRalgorithm can improve the call admission ratio of QoS traffic, the packet delivery ratio, and theend-to-end delay of both best-effort traffic and QoS traffic. Therefore, QoS-MSR with MBSR is anefficient mechanism that supports QoS for ad hoc networks.

关键词： ad hoc network quality of service (QoS) multipath source routing bandwidthreservation

DIAGNOSIS AND TREATMENT OF MALIGNANT PANCREATICENDOCRINE TUMOUR

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Chinese Medical Sciences Journal 2004年第2期19卷 130-133页

作者： leiwang Yu-peiZhao Chia-ILee QuanLiao DepartmentofSurgery PekingUnionMedicalCollegeHospitalChineseAcademyofMedicalScience＆PekingUnionMedicalCollegeBeijing100730

Objective To summarize our experience in the diagnosis and treatment of malignant pancreatic endocrine tumour. Methods We retrospectively reviewed 36 cases of malignant pancreatic endocrine tumours in our hospital from July 1987 to April 2002, and summarized its clinical features. Results Liver metastasis was the main malignant manifestation of malignant pancreatic endocrine tumours (incidence rate 72.2%). Removals of primary lesion and isolated hepatic metastatic lesion were means of curative therapy. Interventional chemotherapy was an important adjuvant treatment. Conclusion Comprehensive therapy plays an important role in improving the prognosis of malignant pancreatic endoc-rine tumour.

关键词： malignant pancreatic endocrine tumour liver metastasis operation interventional chemotherapy

Multienzyme co-immobilization-based bioelectrode:Design of principles and bioelectrochemical applications

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Chinese Journal of Chemical Engineering 2020年第8期28卷 2037-2050页

作者： Ranran Wu Haiyan Song Yuanming Wang leiwang Zhiguang Zhu Tianjin Institute of Industrial Biotechnology Chinese Academy of Sciences32West Seventh AvenueTianjin Airport Economic AreaTianjin 300308China University of Chinese Academy of Sciences 19A Yuquan RoadShijingshan DistrictBeijing 100049China National Human Genetic Resource Center 12 Dahuisi RoadHaidian DistrictBeijing 100081China

Enzyme cascade reactions play significant roles in bioelectrochemical processes because they permit more complex reactions. Co-immobilization of multienzyme on the electrode could help to facilitate substrate/intermediate transfer among different enzymes and electron transfer from enzyme active sites to the electrode with high stability and retrievability. Different co-immobilization strategies to construct multienzyme bioelectrodes have been widely reported, however, up to now, they have barely been reviewed. In this review, we focus on recent state-of-the-art techniques for constructing co-immobilized multienzyme electrodes including random and positional co-immobilization. Particular attention is given to strategies such as multienzyme complex and surface display. Cofactor co-immobilization on the electrode is also crucial for the enhancement of catalytic reaction and electron transfer, yet, few studies have been reported. The up-to-date advances in bioelectrochemical applications of multienzyme bioelectrodes are also presented. Finally, key challenges and future perspectives are discussed.

关键词： Multienzyme co-immobilization Bioelectrode Bioelectrochemical system Cascade reaction

Vortex dynamics over an airfoil controlled by a nanosecond pulse discharge plasma actuator at low wind speed

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Plasma Science and Technology 2019年第12期21卷 85-96页

作者： Hai DU leiwang Wenjie KONG Zhiwei SHI Keming CHENG Zheng LI School of Energy and Power Engineering Xihua UniversityChengdu 610039People's Republic of China Key Laboratory of Fluid and Power Machinery Ministry of EducationXihua UniversityChengdu 610039People's Republic of China College of Aerospace Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016People's Republic of China

The vortex dynamics of flow over an airfoil controlled by a nanosecond pulse dielectric-barrierdischarge(NS-DBD) actuator is studied at a Reynolds number of 1?×?10~5 through wind tunnel experiments and numerical simulation. The numerical method is validated through comparison of the simulated and measured results regarding the effect of the discharge of an NS-DBD actuator placed on a flat plate. The simulated results show that vorticity is mainly induced by the baroclinic torque after plasma discharge, i.e. the term(■) in the equation of vorticity evolution. Both experimental and simulated results demonstrate that after the discharge of the NS-DBD actuator a series of vortices are developed in the shear layer and pull the high-moment fluid down to the wall, enhancing the mixing of internal and external flows.

关键词： plasma actuator flow control Joule heating vortex

Seasonal variation and sources of atmospheric polycyclic aromatic hydrocarbons in a background site on the Tibetan Plateau

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Journal of Environmental Sciences 2023年第3期125卷 524-532页

作者： Xuemei Wu Weijun Sun Baojuan Huai leiwang Chuntan Han Yetang Wang Wenying Mi College of Geography and Environment Shandong Normal UniversityJinan 250014China Qilian Alpine Ecology and Hydrology Research Station Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China MINJIE Institute of Environmental Science and Health Research Geesthacht 21502Germany

The study of atmospheric polycyclic aromatic hydrocarbons(PAHs) in northeastern Tibetan Plateau with fragile ecological environment and complex atmospheric circulation system is blank. To understand the characteristics and sources of persistent organic pollutants in the atmosphere of the northeastern Tibetan Plateau, we monitored levels in the central Qilian Mountain. From 2016 to 2017, we collected 45-pair(particle + gas) samples using active air samplers to investigate the sources, transport paths, and their influencing *** of PAHs were analysed with a source diagnostic model, and atmospheric transport paths were calculated. The concentration range for Σ15PAHs was 439–4666 pg/m^(3), and the average was 2015 pg/m^(3). The PAHs in central Qilian Mountain are mainly low molecular weight(LMW) PAHs. Winter concentrations of PAHs were higher than those in summer. The transport of PAHs is mainly affected by westerlies, and there are seasonal differences. Source analysis showed that PAHs mainly came from coal and biomass combustion and vehicle emissions, with seasonal differences. This study clarifies the concentration and seasonal variation of PAHs in the northern Tibetan Plateau, which is conducive to understanding the atmospheric transport process and fate of pollutants. The background site of Qilian Mountains located in the Silk Road economic belt has the value and significance of longterm observation of pollutants.

关键词： Long-range atmospheric transport Seasonal variation concentration Meteorological factors Qilian Mountain

Screening and identification of functional bacterial attachment genes in aerobic granular sludge

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Journal of Environmental Sciences 2024年第7期141卷 205-214页

作者： Kai Qiao Tingting Zhao leiwang Wei Zhang WeiMeng Fan Liu Xu Gao Jianrong Zhu School of Environment Beijing Normal UniversityBeijing 100875China State Key Laboratory of Water Simulation Beijing 100875China R&D Centre of Aerobic Granule Technology Beijing 100875China

The screening and identification of attachment genes is important to exploring the formation mechanism of biofilms at the gene *** is helpful to the development of key culture technologies for aerobic granular sludge(AGS).In this study,genome-wide sequencing and gene editing were employed for the first time to investigate the effects and functions of attachment genes in *** the help of whole-genome analysis,ten attachment genes were screened from thirteen genes,and the efficiency of gene screening was greatly ***,two attachment genes were selected as examples to further confirm the gene functions by constructing gene-knockout recombinant mutants of Stenotrophomonas maltophilia;when the two attachment genes were knocked out,the attachment potential was reduced by 50.67%and 43.93%,*** results provide a new theoretical principle and efficient method for the development of AGS from the perspective of attachment genes.

关键词： Attachment gene Genome-wide sequence Gene-knockout Attachment potential Aerobic granular sludge biofilm

The Mechanism of Antimicrobial Peptide MPX against Enterohemorrhagic Escherichia coli in Vitro

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The Mechanism of Antimicrobial Peptide MPX against Enterohem...

Antimicrobial peptide MPX relieves Enterohemorrhagic Escherichia coli-induced Intestinal Inflammation by Improving the Diversity of Intestinal Flora

中国微生物学会兽医微生物学专业委员会暨中国畜牧兽医学会生物制品学分会2021年学术论坛

作者： XueqinZhao ChunlingZhu leiwang HannaFotina JianheHu Sumy National Agrarian University College of Animal Science and Veterinary Medicine Henan Institute of Science and Technology College of Veterinary Medicine JiLin University

Escherichia coli is a facultative anaerobic bacteria that exists in the gastrointestinal tract of humans and *** can cause diarrhea,enteritis,destruction of the host’s intestinal barrier,and intestinal microecological *** has a high lethality rate *** brings a huge threat to the development of animal husbandry and human *** recent years,due to the abuse of traditional antibiotics,a variety of drug-resistant strains and super bacteria have emerged in an endless ***,there is an urgent need to find new alternatives to *** peptides are a type of small peptides produced when organisms resist the invasion of foreign *** are an important part of the body’s innate immune system and have a variety of biological functions,such as anti-bacterial,anti-virus,anti-parasitic,promote wound healing and immune regulation and other *** with traditional antibiotics,antimicrobial peptides have the characteristics of small molecular weight,good water solubility,good thermal stability,unique antibacterial mechanism,broad-spectrum antibacterial activity against clinically resistant strains,and resistance to bacterial *** are considered to be the best alternative to antibiotics which has become a research hotspot in recent *** antimicrobial peptide MPX is extracted from wasp venom and has a good bactericidal effect on many *** the early stage of our research group,it has found that MPX has a good bactericidal effect on Actinobacillus pleuropneumoniae, with a minimum inhibitory concentration(MIC) of 16 ug/*** explore the effect of antimicrobial peptide MPX against *** function of antimicrobial peptide MPX against *** was detected by MIC,plate count,propidium iodide,NPN and DiSC(c5) permeability testing,immunofluorescence microscope observation,and the impact of MPX stability by temperature,pH,*** this study,the results of the antibacterial activity test

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Antimicrobial peptide MPX relieves Enterohemorrhagic Escheri...