检索结果-南通市图书馆

The global COVID-19 vaccine surplus:tackling expiring stockpiles

在线全文

学校读者我要写书评

暂无评论

Infectious Diseases of Poverty 2023年第2期12卷 106-111页

作者： nguyen Khoi Quan nguyen Le My Anh Andrew W.Taylor-Robinson College of Health Sciences VinUniversityGia Lam DistrictHanoi100000Vietnam Faculty of Medicine Imperial College LondonLondonSW72AZUK Center for Global Health Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPA19104USA

Background A global surplus of coronavirus disease 2019(COVID-19)vaccines exists as a result of difficulties in aligning the demand and supply for vaccine manufacturing and *** leaders have accelerated vaccine development,approval,production and distribution as a pragmatic approach to addressing the immediate public health challenges of the first two and a half years of the *** body The currently predominant,highly transmissible Omicron variant of severe acute respiratory syndrome coronavirus 2 has brought us closer to the threshold required to achieve herd immunity by greatly increasing rates of natural ***,in parallel with rising vaccination levels in industrialized nations,this indirectly reduces the need for mass vaccine *** concerns that contribute to low vaccination rates which persist in several other countries,particularly of the Global South,are vaccine hesitancy and unequal access to *** uncertainty fueled by fake news,misinformation,unfounded lay opinions and conspiracy theories has inevitably led to an erosion of public trust in *** To address the current mismatch between supply and demand of COVID-19 vaccines,there should be a focus on three principles:decelerating vaccine production,increasing distribution across communities,and optimizing cost-effectiveness of distribution *** down and switching from large-scale production to effectively‘made to order’is a feasible option,which should be commensurate with management *** and evidence-based data should be widely and freely disseminated to the public through multimedia channels to mitigate miscommunication and conspiracy *** of soon-to-expire stockpiles should be prioritized not only to enhance booster dose rollouts in adults but to expand immunization campaigns to children(especially those aged 5–11 years),subject to national *** research should ideally aim to de

关键词： COVID-19 SARS-CoV-2 Omicron Vaccination Immunization Vaccine surplus Vaccine hesitancy Vaccine reluctance Vaccine inequity

A Uniformly Robust Staggered DG Method for the Unsteady Darcy-Forchheimer-Brinkman Problem

在线全文

学校读者我要写书评

暂无评论

Communications on Applied Mathematics and Computation 2022年第1期4卷 205-226页

作者： Lina Zhao Ming Fai lam Eric Chung Department of Mathematics The Chinese University of Hong KongHong Kong SARChina

In this paper,we propose and analyze a uniformly robust staggered DG method for the unsteady Darcy-Forchheimer-Brinkman *** formulation is based on velocity gradient-velocity-pressure and the resulting scheme can be flexibly applied to fairly general polygonal *** relax the tangential continuity for velocity,which is the key ingredi-ent in achieving the uniform *** present well-posedness and error analysis for both the semi-discrete scheme and the fully discrete scheme,and the theories indicate that the error estimates for velocity are independent of *** numerical experiments are presented to confirm the theoretical findings.

关键词： Staggered DG method Brinkman-Forchheimer General meshes Uniformly stable

Performance of CdS/CdSe/ZnS quantum dot-sensitized TiO_2 mesopores for solar cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Optics Letters 2013年第7期11卷 66-69页

作者： Tung Ha Thanh Quang Vinh lam Thai Hoang nguyen Thanh Dat Huynh Faculty of Physics Dong Thap University Dong Thap Province University of Science Viet Nam National University Ho Chi Minh City Viet Nam National University Ho Chi Minh City

We prepare CdS/CdSe/ZnS thin films by successive ionic layer adsorption and reaction method. Results show a wider photoresponse range of TiO2 mesopores from the ultraviolet region to the visible light region. Sequentially assembled CdS/CdSe/ZnS quantum and photocurrent efficiency. A high efficiency of dots exhibit significantly improved light-harvesting ability 1.059354% is obtained.

关键词： CdSe Performance of CdS/CdSe/ZnS quantum dot-sensitized TiO2 mesopores for solar cells ZnS TiO

Is engineered wood China’s way to carbon neutrality?

在线全文

学校读者我要写书评

暂无评论

Journal of Bioresources and Bioproducts 2022年第2期7卷 1-2页

作者： Christian Sonne Changlei Xia Su Shiung lam Department of Ecoscience Faculty of Technological SciencesAarhus UniversityRoskilde DK-4000Denmark Sustainability Cluster School of EngineeringUniversity of Petroleum&Energy StudiesUttarakhand 248007India Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources International Innovation Center for Forest Chemicals and MaterialsCollege of Materials Science and EngineeringNanjing Forestry UniversityNanjing 210037China Higher Institution Centre of Excellence(HICoE) Institute of Tropical Aquaculture and Fisheries(AKUATROP)Universiti Malaysia Terengganu21030 Kuala NerusTerengganuMalaysia

China emits more than 25%of the world’s carbon dioxide(https://***/co2-emissions),and in December 2021 the country’s daily carbon trading volume hits a new highest *** with the EU and USA,China bears a great responsibility to limit global warming to 2℃,and therefore recently launches a plan to be carbon-neutral be-fore 2060(https://***/co2-emissions).However,its rapid urbanization challenges this initiative as the boom-ing building and construction industry constitute more than 1/3 of the total energy consumption,which undesirably in-creases carbon emissions(IEA,2019;Duan et al.,2021).Although China has built five new nuclear power stations and closed down more than 1000 coal-fired power plants,it is still highly insufficient to meet the country’s goal to be carbon-neutral(https://***/countries/china/).

关键词： Climate change Engineered wood Carbon neutrality Building material China

Superior antibody and membrane protein‑specific T‑cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2024年第4期20卷 353-370页

作者： Jaime S.Rosa Duque Samuel M.S.Cheng Carolyn A.Cohen Daniel Leung Xiwei Wang Xiaofeng Mu Yuet Chung Tsun Ming Lau Manni Wang Wenyue Zhang Yanmei Zhang Howard H.W.Wong Leo C.H.Tsang Sara Chaothai Tsz Chun Kwan John K.C.Li Karl C.K.Chan Leo L.H.Luk Jenson C.H.Ho Wing Yan Li Amos M.T.Lee Jennifer H.Y.lam Sau Man Chan Wilfred H.S.Wong Issan Y.S.Tam Masashi Mori Sophie A.Valkenburg Malik Peiris Wenwei Tu Yu Lung Lau Department of Paediatrics and Adolescent Medicine The University of Hong KongHong KongChina School of Public Health The University of Hong KongHong KongChina HKU‑Pasteur Research Pole School of Public HealthThe University of Hong KongHong KongChina Research Institute for Bioresources and Biotechnology Ishikawa Prefectural UniversityNonoichiJapan Department of Microbiology and Immunology Peter Doherty Institute for Infectionand ImmunityUniversity of MelbourneMelbourneVICAustralia Center for Immunology and Infection C2i Hong KongChina

Background Optimising the immunogenicity of COVID-19 vaccines to improve their protection against disease is *** dosing by intradermal(ID)administration has been shown to be equally immunogenic as intramuscular(IM)administration for several vaccines,but the immunogenicity of ID inactivated whole severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)at the full dose is *** study(NCT04800133)investigated the superiority of antibody and T-cell responses of full-dose CoronaVac by ID over IM administration in *** Participants aged 11–17 years received two doses of IM or ID vaccine,followed by the 3rd dose 13–42 days *** and cellular immunogenicity outcomes were measured post-dose 2(IM-CC versus ID-CC)and post-dose 3(IMCCC versus ID-CCC).Doses 2 and 3 were administered to 173 and 104 adolescents,*** Spike protein(S)immunoglobulin G(IgG),S-receptor-binding domain(RBD)IgG,S IgG Fcγreceptor IIIa(FcγRIIIa)-binding,SNM[sum of individual(S),nucleocapsid protein(N),and membrane protein(M)peptide pool]-specific interleukin-2(IL-2)+CD4^(+),SNM-specific IL-2^(+)CD8^(+),S-specific IL-2^(+)CD8^(+),N-specific IL-2^(+)CD4^(+),N-specific IL-2^(+)CD8^(+)and M-specific IL-2^(+)CD4^(+)responses fulfilled the superior and non-inferior criteria for ID-CC compared to IM-CC,whereas IgG avidity was *** ID-CCC,S-RBD IgG,surrogate virus neutralisation test,90%plaque reduction neutralisation titre(PRNT90),PRNT50,S IgG avidity,S IgG FcγRIIIa-binding,M-specific IL-2^(+)CD4^(+),interferon-γ+CD8^(+)and IL-2^(+)CD8^(+)responses were superior and non-inferior to *** estimated vaccine efficacies were 49%,52%,66%and 79%for IM-CC,ID-CC,IM-CCC and ID-CCC,*** ID groups reported more local,mild adverse *** This is the first study to demonstrate superior antibody and M-specific T-cell responses by ID inactivated SARSCoV-2 vaccination and serves as the basis for future research to improve the

关键词： CoronaVac Coronavirus disease 2019 Immunity Intradermal Vaccine

闪动疗法对童年创伤经历大学生焦虑情绪的干预

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国临床心理学杂志 2024年第1期32卷 222-226页

作者：凌辉刘慧玥周雯雯颜雅琴黄锡林张建人湖南师范大学认知与人类行为湖南省重点实验室长沙410082 湖南省心理健康教育研究基地长沙410081 湖南第一师范学院心理健康教育中心长沙410205 美国加州州立大学东湾分校旧金山94707 海南医学院附属海南省妇女儿童医学中心海南省热带脑科学研究与转化重点实验室海口571199

目的:探究闪动疗法对童年创伤经历大学生焦虑情绪的干预效果。方法:采用随机对照实验设计,将16名童年创伤经历大学生分为干预组和对照组,每组8人。干预组接受每周1次,每次90分钟,共8次闪动疗法线上干预,对照组不进行任何处理。干预前后... 详细信息

目的:探究闪动疗法对童年创伤经历大学生焦虑情绪的干预效果。方法:采用随机对照实验设计,将16名童年创伤经历大学生分为干预组和对照组,每组8人。干预组接受每周1次,每次90分钟,共8次闪动疗法线上干预,对照组不进行任何处理。干预前后采用焦虑自评量表评定焦虑情绪,用定量和定性的方法评估干预效果。结果:闪动疗法可以显著缓解干预组的焦虑情绪,促进生理、心理及社会生活方面的积极改变,对照组无明显变化。结论:本研究初步证明闪动疗法对童年创伤经历大学生的焦虑情绪具有一定的干预效果。

关键词：闪动疗法童年创伤经历大学生焦虑效果评估

Phosphatidylcholine deficiency increases ferroptosis susceptibility in the Caenorhabditis elegans germline

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Journal of Genetics and Genomics 2023年第5期50卷 318-329页

作者： Jinglin Zhu Wei Meng Sin Man lam Guanghou Shui Xun Huang State Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China

Ferroptosis,a regulated and iron-dependent form of cell death characterized by peroxidation of membrane phospholipids,has tremendous potential for the therapy of human *** causal link between phospholipid homeostasis and ferroptosis is incompletely ***,we reveal that spin-4,a previously identified regulator of the“B12-one-carbon cycle-phosphatidylcholine(PC)”pathway,sustains germline development and fertility by ensuring PC sufficiency in the nematode Caenorhabditis ***,SPIN-4 regulates lysosomal activity which is required for B12-associated PC *** deficiency-induced sterility can be rescued by reducing the levels of polyunsaturated fatty acids,reactive oxygen species,and redox-active iron,which indicates that the sterility is mediated by germline *** results highlight the critical role of PC homeostasis in ferroptosis susceptibility and offer a new target for pharmacological approaches.

关键词： Phosphatidylcholine Ferroptosis SPIN-4 Sterility Lysosome

Effect of heating time on structural,morphology,optical,and photocatalytic properties of g-C3N4 nanosheets

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2020年第5期29卷 504-508页

作者： nguyen Manh Hung Le Thi Mai Oanh lam Thi Hang Pham Do Chung Pham Thi Duyen Dao Viet Thang nguyen Van Minh Center for Nano Science and Technology Hanoi National University of Education136 Xuan Thuy RoadCau Giay DistrictHanoi100000Vietnam Department of Physics Hanoi National University of Education136 Xuan Thuy RoadCau Giay DistrictHanoi100000Vietnam Faculty of Basic Sciences Hanoi University of Natural Resources and Environment41A Phu Dien RoadNorth Tu LiemHanoi100000Vietnam Hanoi University of Mining and Geology Duc Thang wardNorth Tu Liem DistrictHanoi100000Vietnam Military science Academy 322 Le Trong Tan streetDinh CongHoang MaiHanoi100000Vietnam

Effect of heating time on the structural,morphology,optical,and photocatalytic properties of graphitic carbon nitride(g-C3N4)nanosheets prepared at 550℃in Ar atmosphere is *** investigations are carried out by using x-ray diffraction(XRD),scanning electron microscopy(SEM),Fourier-transform infrared spectroscopy(FTIR),UV-vis absorption,and photoluminescence(PL).At a heating temperature of 550℃,g-C3N4 nanocrystals are formed after 0.5 h and become more orderly as the heating time *** surface area of the g-C3N4 nanosheets significantly increases as the preparation time *** g-C3N4 prepared in 2.5 h shows the highest photocatalytic performance,decomposing completely 10 ppm RhB solution under xenon lamp irradiation for 2.0 h.

关键词： nanosheets photocatalytic heating time Ar atmosphere

Tapered optical fiber DNA biosensor for detecting Leptospira DNA

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2023年第3期16卷 119-128页

作者： Jia-Yong lam Mohd Hanif Yaacob Hui-Yee Chee Department of Medical Microbiology Faculty of Medicine and Health SciencesUniversiti Putra Malaysia43400 UPM SerdangSelangorMalaysia Department of Computer and Communication Systems Engineering Faculty of EngineeringUniversiti Putra Malaysia43400 UPM SerdangSelangorMalaysia Wireless and Photonics Networks Research Centre(WiPNET) Universiti Putra Malaysia43400 UPM SerdangSelangorMalaysia

Objective: To establish a DNA detection platform based on a tapered optical fiber to detect Leptospira DNA by targeting the leptospiral secY ***: The biosensor works on the principle of light propagating in the special geometry of the optical fiber tapered from a waist diameter of 125 to 12 μm. The fiber surface was functionalized through a cascade of chemical treatments and the immobilization of a DNA capture probe targeting the secY gene. The presence of the target DNA was determined from the wavelength shift in the optical transmission ***: The biosensor demonstrated good sensitivity, detecting Leptospira DNA at 0.001 ng/μL, and was selective for Leptospira DNA without cross-reactivity with non-leptospiral microorganisms. The biosensor specifically detected DNA that was specifically amplified through the loop-mediated isothermal amplification ***: These findings warrant the potential of this platform to be developed as a novel alternative approach to diagnose leptospirosis.

关键词： DNA biosensor Tapered optical fiber Leptospirosis Leptospira