The global COVID-19 vaccine surplus:tackling expiring stockpiles

作     者：Nguyen Khoi Quan Nguyen Le My Anh Andrew W.Taylor-Robinson Nguyen Khoi Quan;Nguyen Le My Anh;Andrew W. Taylor-Robinson

作者机构：College of Health SciencesVinUniversityGia Lam DistrictHanoi100000Vietnam Faculty of MedicineImperial College LondonLondonSW72AZUK Center for Global HealthPerelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPA19104USA 

出 版 物：《Infectious Diseases of Poverty》 (贫困所致传染病（英文）)

年 卷 期：2023年第12卷第2期

页      面：106-111页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：No funding was received to conduct this study 

主　　题：COVID-19 SARS-CoV-2 Omicron Vaccination Immunization Vaccine surplus Vaccine hesitancy Vaccine reluctance Vaccine inequity 

摘      要：Background A global surplus of coronavirus disease 2019(COVID-19)vaccines exists as a result of difficulties in aligning the demand and supply for vaccine manufacturing and *** leaders have accelerated vaccine development,approval,production and distribution as a pragmatic approach to addressing the immediate public health challenges of the first two and a half years of the *** body The currently predominant,highly transmissible Omicron variant of severe acute respiratory syndrome coronavirus 2 has brought us closer to the threshold required to achieve herd immunity by greatly increasing rates of natural ***,in parallel with rising vaccination levels in industrialized nations,this indirectly reduces the need for mass vaccine *** concerns that contribute to low vaccination rates which persist in several other countries,particularly of the Global South,are vaccine hesitancy and unequal access to *** uncertainty fueled by fake news,misinformation,unfounded lay opinions and conspiracy theories has inevitably led to an erosion of public trust in *** To address the current mismatch between supply and demand of COVID-19 vaccines,there should be a focus on three principles:decelerating vaccine production,increasing distribution across communities,and optimizing cost-effectiveness of distribution *** down and switching from large-scale production to effectively‘made to order’is a feasible option,which should be commensurate with management *** and evidence-based data should be widely and freely disseminated to the public through multimedia channels to mitigate miscommunication and conspiracy *** of soon-to-expire stockpiles should be prioritized not only to enhance booster dose rollouts in adults but to expand immunization campaigns to children(especially those aged 5–11 years),subject to national *** research should ideally aim to de