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FACtORS AFFECtING VENtILAtION,INDOOR-AIR QUALItY AND ACOUStICAL QUALItY IN‘GREEN’AND NON-‘GREEN’BUILDINGS:A PILOt StUDY

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Journal of Green Building 2011年第3期6卷 168-180页

作者： Alireza Khaleghi karen Bartlett Murray Hodgson Department of Mechanical Engineering University of British Columbia6250 Applied Sciences LaneVancouverBCCanada V6T1Z3 School of Population and Public Health University of British Columbia School of Population and Public Health(and Department of Mechanical Engineering) University of British Columbia

this paper discusses a pilot project involving the direct monitoring of ventilation,indoor-air quality and the acoustical conditions in selected nominally‘green’and non-‘green’buildings located on a university *** objectives were to measure parameters quantifying these three aspects of indoor environmental quality,determine the relationships between them and the building-design concepts,and evaluate the implications of the results for ventilation-system design,especially in‘green’*** were made in rooms,with and without acoustical treatment,in buildings with natural ventilation or mechanical(displacement and/or mixed-flow)ventilation *** were made of ventilation rates(air changes per hour),indoor air quality(respirable-fibre,total-VOC and ultrafine-particulate concentrations),and the acoustical conditions(noise levels and reverberation times).Correlations between the environmental results,the building concept,the ventilation concept and the building window status were *** rooms with natural ventilation,low-frequency noise and total sound-pressure levels were lower;however,the rooms had higher ultrafine-particulate counts and lower ventilation *** with mechanical ventilation had higher low-frequency and total sound-pressure levels,higher ventilation rates and fibre concentrations,but lower concentrations of ultrafine *** was concluded that,in general,mechanical ventilation can provide better indoor air-quality,but that HVAC noise is an issue if the system is not properly ***‘green’buildings,noise levels were acceptable when the windows were closed,but increasing the ventilation rate by opening the windows resulted in higher noise *** results suggest that the acceptability of environmental factors in buildings depends on the degree of compliance of the design and its implementation with standards and design guidelines(*** ventilation,air quality,thermal comfort,etc.),whether the o

关键词： green building conventional building ventilation quality indoor-air quality acoustical conditions mechanical ventilation natural ventilation

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Vedolizumab use in patients with inflammatory bowel diseases undergoing surgery:clinical trials and post-marketing experience

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Gastroenterology Report 2019年第5期7卷 322-330,I0001页

作者： Bo Shen Aimee Blake karen Lasch Michael Smyth Fatima Bhayat Center for Inflammatory Bowel Disease Digestive Disease and Surgery InstituteCleveland ClinicClevelandOHUSA Global Patient Safety Evaluation Takeda Pharmaceuticals International Co.CambridgeMAUSA US Medical Office Takeda Pharmaceuticals USA Inc.DeerfieldILUSA Global Medical Affairs Takeda Development Centre Europe LtdLondonUK Kyowa Kirin International plc ChertseyUK

Background:Patients with inflammatory bowel diseases frequently require surgery,but immunotherapies used in disease management may increase the risk of post-operative *** investigated frequencies of post-operative complications in patients who received vedolizumab—a gut-selective antibody approved for the treatment of moderately to severely active ulcerative colitis and Crohn’s disease—in clinical-trial and post-marketing ***:this post hoc analysis of safety data from GEMINI 1,GEMINI 2,and long-term safety studies included patients who had had colectomy or bowel surgery/*** from the post-marketing Vedolizumab Global Safety Database were also analysed(data cutoff point:19 May 2016).Adverse events relating to post-operative complications were identified using Medical Dictionary for Regulatory Activities preferred ***:Of 58 total surgeries in patients included in GEMINI 1 and GEMINI 2,post-operative complications were reported for 3/51 vedolizumab-treated patients(5.9%)and 1/7 placebo-treated patients(14.3%).In the long-term safety study,157/2,243 patients(7%)had colectomy or bowel surgery/resection;of these 157 patients who underwent surgery,11(7%)experienced a post-operative *** time between last pre-operative vedolizumab dose and surgery was 23 days in GEMINI 1,20 days in GEMINI 2,and 39–40 days in the long-termsafety *** the post-marketing setting,based on data covering approximately 46,978 patient-years of vedolizumab exposure,post-operative complications were reported in 19 ***:In clinical trials,complications of colectomy and bowel surgery/resection appeared infrequent,with minimal difference between vedolizumab and *** frequency of post-operative complications in the post-marketing setting appears low.

关键词： inflammatory bowel disease colorectal surgery vedolizumab

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Characterising acute ischaemic stroke thrombi:insights from histology,imaging and emerging impedance-based technologies

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Stroke & Vascular Neurology 2022年第4期7卷 353-363页

作者： Smita Patil Jean Darcourt Pierluca Messina Franz Bozsak Christophe Cognard karen Doyle CÚRAM SFI Research Centre for Medical DevicesNational University of Ireland GalwayGalwayIreland Neuroradiology CHU de ToulouseToulouseFrance Sensome MassyFrance Physiology National University of Ireland GalwayGalwayIreland

treatment of acute ischaemic stroke(AIS)focuses on rapid recanalisation of the occluded *** recent years,advent of mechanical thrombectomy devices and new procedures have accelerated the analysis of thrombi retrieved during the endovascular thrombectomy *** ongoing developments and progress in AIS imaging techniques,it is not yet possible to conclude definitively regarding thrombus characteristics that could advise on the probable efficacy of thrombolysis or thrombectomy in advance of *** devices with dignostic capabilities or new clinical imaging approaches are needed for better treatment of AIS *** this review,what is known about the composition of the thrombi that cause strokes and the evidence that thrombus composition has an impact on success of acute stroke treatment has been *** review also discusses the evidence that AIS thrombus composition varies with aetiology,questioning if suspected aetiology could be a useful indicator to stroke physicians to help decide the best acute course of ***,this review discusses the evidence that current widely used radiological imaging tools can predict thrombus *** use of new emerging technologies based on bioimpedance,as imaging modalities for diagnosing AIS and new medical device tools for detecting thrombus composition in situ has been *** bioimpedance would be beneficial for gaining new insights into in situ thrombus composition that could guide choice of optimum treatment approach is also reviewed.

关键词： throm acute impedance

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Enhanced structural stability of adenovirus nanocapsule

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Progress in Natural Science:Materials International 2014年第2期24卷 171-174页

作者： Ding Weng Ziyue karen Jiang Jing Jin Lily Wu Yunfeng Lu Chemical and Biomolecular Engineering University of California at Los Angeles tissue Engineering Laboratories VA Boston Healthcare System Department of Orthopaedic Surgery Brigham and Women's Hospital Harvard Medical School Molecular and Medical Pharmacology University of California at Los Angeles Getein Biotechnology Co. Ltd.

Application of viral vector in gene therapy and vaccination is still limited by their structural stability, which significantly increased avoidable cost in storage and transportation. Herein a non-covalent conjugated low-pH degradable nanocapsule has been adopted to stabilize viral vectors. By utilizing a luciferase expressing adenovirus, AdCMVLuc, we succeeded in a raise of over 11 folds in AdCMVLuc’s structural stability after 12 days storage at 4 1℃.

关键词： Non-covalent nanocapsule Adenovirus Structural stability

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the Organizer Dilemma: Outcomes from a Collaboration Exercise

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International Journal of Disaster Risk Science 2019年第2期10卷 261-269页

作者： Jarle Lowe Sorensen Eric D.Carlstrom Glenn-Egil torgersen Atle M.Christiansen tae-Eun Kim Stig Wahlstrom Leif inge Magnussen Department of Business History and Social SciencesSchoolof BusinessUniversity of South-Eastern NorwayCampusVestfold3199BorreNorway Institute of Health and Care Sciences University ofGothenburgSE-40530GoteborgSweden Department of Military Leadership and Management TheNorwegian Defence University CollegeN-0151OsloNorway Department of Maritime Operations Faculty of TechnologyNatural Sciences and Maritime SciencesUniversity ofSouth-Eastern NorwayCampus Vestfold3199BorreNorway Norwegian Coastal Administration N-6025 AlesundNorway

In crisis management, cross-sector collaboration exercises are perceived as improving preparedness and develop team-integration efforts. However, studies show that exercises may tend to produce results with limited learning and usefulness. the purpose of this nonexperimental, survey-based study was to measure the difference in perceived exercise effect between participants belonging to the exercise planning organizations and participants belonging to other participating groups. Surveys were distributed and collected from participants in a 2017 chemical oil-spill exercise set off the southern coast of Norway. the target population was operational staff,excluding exercise management and directing staff. the sample population consisted of operatives associated with the exercise organizer organization and others belonging to external public and nongovernmental emergency organizations. the data collection instrument was the 'Collaboration, Learning, and Utility Scale’’(CLU-scale). Findings indicated that the levels of CLU were higher among external participants than among those individuals who belong to the exercise planning organizations. this study recommends the development and adoption of a national maritime collaboration exercise framework. A practical implication is a recommendation to evaluate exercises to secure the outcome regarding collaboration skill using the same instrument.

关键词： Collaboration exercise Collaboration,Learning,and Utility Scale Crisis management Maritime emergencies and crises Norway

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Dreams of falling

Dreams of falling

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作者： karen White.

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Social cliques in male northern muriquis Brachyteles hypoxanthus

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Current Zoology 2012年第2期58卷 342-352页

作者： Marcos tOKUDA Jean P. BOUBLI Patricia IZAR karen B. StRIER Department of Experimental Psychology University of S~io Paulo Av. Prof. Mello Moraes 1721 CEP 05508-030 Sao Paulo Brazil Wildlife Conservation Society Rio de Janeiro Brazil Department of Anthropology University of Wisconsin-Madison USA

Analyses of spatial relationships and social interactions provide insights into the social structure of animal societies and the ways in which social preferences among and between dyads affect higher order social relationships. In this paper we de- scribe the patterns of spatial associations and social interactions among adult male northern muriquis in order to evaluate the dy- namics of their social networks above the dyadic levels. Systematic observations were made on the 17 adult males present in a multi-male/multi-female group from April 2004 through February 2005, and in July 2005. Analyses of their spatial relationships identified two distinct male cliques; some adult males （called ＂N＂ males） were more connected to the females and immatures than other adult males （＂MU＂ males）, which were more connected to one another. Affiliative interactions were significantly higher among dyads belonging to the same clique than to different cliques. Although frequencies of dyadic agonistic interactions were similarly low among individuals within and between cliques, MU males appeared to be subordinate to N males. Nonetheless, there were no significant differences in the copulation rates estimated for MU males and N males. Mutual benefits of cooperation between MU and N cliques in intergroup encounters might explain their ongoing associations in the same mixed-sex group

关键词： Brachyteles hypoxanthus Male northern muriquis Social relationship Social clique Social network analysis

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Editing landscapes:Experimental frameworks for territorial-based robotic fabrication

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Frontiers of Architectural Research 2023年第1期12卷 104-117页

作者： karen Lee Bar-Sinai tal Alon-Mozes Aaron Sprecher Faculty of Architecture and town Planning Technion-Israel Institute of TechnologyHaifa 3200003Israel

With the advent of on-site robotic tools,they can be deployed for editing landscapes e defined as the modulation of grounds with a high degree of sensitivity to matter and *** paper contributes a theoretical grounding and two experimental frameworks for territorial-based robotic *** experimental framework supports a robotic capacity for informing and forming grounds,demonstrated in relation to extreme territories using simulation *** frameworks include(1)a layer-sensitive modulation for protecting topsoil and(2)a performance-based robotic forming for creating wind *** each framework,the paper proposes a setup,an exploration method,and an evaluation *** on the presented frameworks,the paper outlines three potentials of territorialbased robotic fabrication:the capability to modulate grounds vertically,the possibility to perform cross-scalar forming,and the opportunity to form dynamic,performative *** paper concludes with potential ways in which robotic tools could be leveraged for advancing precise landscape editing across scales.

关键词： Landscape modulation Robotic fabrication Informing grounds Performative design territorial-based design

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地方性环境保护政策的未预后果:以天津水源保护措施为例

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广东社会科学 2017年第1期 213-223页

作者：谭宏泽 Geir inge Orderud 香港城市大学挪威奥斯陆和阿克斯大学应用科学院

二十世纪九十年代起,为保护天津市饮用水源地,一系列地方性环保政策和措施被制定和实施。这些措施普遍具有"剥离性"特质,并带来一系列后果:居民和水库的联系被割裂;当地居民归属感被削弱;政府介入传统的居民与环境的互动过程等。同时,... 详细信息

二十世纪九十年代起,为保护天津市饮用水源地,一系列地方性环保政策和措施被制定和实施。这些措施普遍具有"剥离性"特质,并带来一系列后果:居民和水库的联系被割裂;当地居民归属感被削弱;政府介入传统的居民与环境的互动过程等。同时,传统农业的边缘化地位使得农业生产方式向粗放式发展。周边村民在与环境的互动中成为"受害的作恶者"和"沉默的智者"。该区域的环境保护处于一个传统约束机制瓦解而新型约束机制缺席的断裂阶段,这也导致环保措施的实际后果偏离最初的预计。

关键词：水源保护地方性政策未预后果天津

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Sexual audience affects male's reproduction investment without consequences on reproductive outputs

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Insect Science 2022年第4期29卷 1170-1180页

作者： Philippe Louâpre karen Muller Soline Bettencourt-Amarante Denis thiery Jérôme Moreau UMR CNRS 6282 Biogeosciences UniversitéBourgogne Franche-ComtéDijonFrance INRA UMR 1065 Santéet Agroecologie du Vignoble Institut des Science de la Vigne et du VinVillenave d'OrnonCedexFrance INRA UMR 1065 SaveUniversitéde BordeauxBordeaux Sciences AgroVillenave d'OrnonCedexFrance

Males evolved plastic strategies to respond to male-male competition and exhibit adaptive traits and behaviors maximizing their access to the females and limiting sperm *** behaviors allow males to express quick responses to current sexual audience,that is,the number of nearby conspecifics prone to *** contrast,physiological responses are frequently delayed because they are constrained by the time and resources having to be mobilized to produce and export sperm and associated *** is especially critical in species for which males produce *** we investigated in what extend moth males(the tortricid moth Lobesia botrana)producing spermatophores exhibit plastic behavioral and physiological responses to different sexual audiences before and during mating and the consequences for their reproductive *** found that males adjusted their mating behaviors and spermatophore size to a potentially elevated risk of sperm competition perceived before *** addition,males responded to the closed presence of females during mating by reducing their mating ***,the various behavioral and physiological responses we highlighted here were not fully reflected in their reproductive performance as we did not reveal any effect on fecundity and fertility of their *** selective pressure exerted on males experiencing male-male competition could thus be sufficient to trigger adjustment in male mating behaviors but constrains physiological responses according to the perception of competition.

关键词： Lobesia borrund male-male compeition mating behavior sexual conflict sexual scletion sperm competition

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