Characterising acute ischaemic stroke thrombi:insights from histology,imaging and emerging impedance-based technologies
作者机构：CÚRAMSFI Research Centre for Medical DevicesNational University of Ireland GalwayGalwayIreland NeuroradiologyCHU de ToulouseToulouseFrance SensomeMassyFrance PhysiologyNational University of Ireland GalwayGalwayIreland
出 版 物：《Stroke & Vascular Neurology》 (卒中与血管神经病学（英文）)
年 卷 期：2022年第7卷第4期
页 面：353-363页
核心收录：
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
基 金：funded by European Regional Development Fund(13/RC/2073_2) Sensome(No grant number),Science Foundation Ireland(13/RC/2073_2)
摘 要：Treatment of acute ischaemic stroke(AIS)focuses on rapid recanalisation of the occluded *** recent years,advent of mechanical thrombectomy devices and new procedures have accelerated the analysis of thrombi retrieved during the endovascular thrombectomy *** ongoing developments and progress in AIS imaging techniques,it is not yet possible to conclude definitively regarding thrombus characteristics that could advise on the probable efficacy of thrombolysis or thrombectomy in advance of *** devices with dignostic capabilities or new clinical imaging approaches are needed for better treatment of AIS *** this review,what is known about the composition of the thrombi that cause strokes and the evidence that thrombus composition has an impact on success of acute stroke treatment has been *** review also discusses the evidence that AIS thrombus composition varies with aetiology,questioning if suspected aetiology could be a useful indicator to stroke physicians to help decide the best acute course of ***,this review discusses the evidence that current widely used radiological imaging tools can predict thrombus *** use of new emerging technologies based on bioimpedance,as imaging modalities for diagnosing AIS and new medical device tools for detecting thrombus composition in situ has been *** bioimpedance would be beneficial for gaining new insights into in situ thrombus composition that could guide choice of optimum treatment approach is also reviewed.
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