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Aquila Optimization with Machine Learning-Based Anomaly Detection Technique in Cyber-Physical Systems

Computer Systems Science & Engineering 2023年第8期46卷 2177-2194页

作者： A.Ramachandran k.Gayathri Ahmed Alkhayyat Rami Q.Malik Department of Computer Science and Engineering University College of EngineeringPanruti607106India Department of Electronics and Communication Engineering University College of EngineeringPanruti607106India College of Technical Engineering The Islamic UniversityNajafIraq Medical Instrumentation Techniques Engineering Department Al-Mustaqbal University CollegeBabylonIraq

Cyber-physical system(CPS)is a concept that integrates every computer-driven system interacting closely with its physical ***-of-things(IoT)is a union of devices and technologies that provide universal interconnection mechanisms between the physical and digital *** the complexity level of the CPS increases,an adversary attack becomes possible in several *** security is a vital aspect of the CPS *** to the massive surge in the data size,the design of anomaly detection techniques becomes a challenging issue,and domain-specific knowledge can be applied to resolve *** article develops an Aquila Optimizer with Parameter Tuned Machine Learning Based Anomaly Detection(AOPTML-AD)technique in the CPS *** presented AOPTML-AD model intends to recognize and detect abnormal behaviour in the CPS *** presented AOPTML-AD framework initially pre-processes the network data by converting them into a compatible ***,the improved Aquila optimization algorithm-based feature selection(IAOA-FS)algorithm is designed to choose an optimal feature *** with that,the chimp optimization algorithm(ChOA)with an adaptive neuro-fuzzy inference system(ANFIS)model can be employed to recognise anomalies in the CPS *** ChOA is applied for optimal adjusting of the membership function(MF)indulged in the ANFIS *** performance validation of the AOPTML-AD algorithm is carried out using the benchmark *** extensive comparative study reported the better performance of the AOPTML-AD technique compared to recent models,with an accuracy of 99.37%.

关键词： Machine learning industry 4.0 cyber-physical systems anomaly detection aquila optimizer

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Influence of welding parameters on material flow,mechanical property and intermetallic characterization of friction stir welded AA6063 to HCP copper dissimilar butt joint without offset

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Transactions of Nonferrous Metals Society of China 2015年第9期25卷 2833-2846页

作者： T.k.BHATTACHARYA H.DAS T.k.PAL Welding Technology Centre Metallurgical and Material Engineering DepartmentJadavpur University

Joining of dissimilar aluminium-copper is an emerging area of interest for both research and industry due to its complex *** stir welding was attempted to evaluate the joint strength without offset at the butt line between AA6063 to HCP copper sheet under different combination of rotational speed of 800 and 1000 r/min and travel speed of 20 and 40 mm/*** flow was studied in detail for different combinations of parameters with optical microscopy and elemental mapping by energy dispersive X-ray spectroscopy（EDS）.The results were correlated with the microstructural characteristics and formation of intermetallics at the bond interface using microhardness test and X-ray diffraction（XRD） *** flow clearly suggests that energy input at 800 r/min and 20 mm/min is sufficient to plasticize both the materials with formation of higher amount of thermodynamically stable and hard intermetallic phases Al4Cu9 and Al Cu4（slower cooling rate of 88 k/s） than that at 800 r/min and 40 mm/min（faster cooling rate of 154 k/s）,attributed maximum joint strength（~78.6% of aluminium base metal）.

关键词： friction stir welding(FSW) AA6063 alloy HCP copper material flow

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Anal squamous cell carcinoma: An evolution in disease and management

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World Journal of Gastroenterology 2014年第36期20卷 13052-13059页

作者： Marc C Osborne Justin Maykel Eric k Johnson Scott R Steele University of Minnesota Minneapolis MN55415 United States University of Massachusetts Memorial Medical Center Worcester MA 01609 United States Department of Surgery Madigan Army Medical Center Tacoma WA 98431 United States

Anal cancer represents less than 1% of all new cancers diagnosed annually in the United States. Yet, despite the relative paucity of cases, the incidence of anal cancer has seen a steady about 2% rise each year over the last decade. As such, all healthcare providers need to be cognizant of the evaluation and treatment of anal squamous cell carcinoma. While chemoradiation remains the mainstay of therapy for most patients with anal cancer, surgery may still be required in recurrent, recalcitrant and palliative disease. In this manuscript, we will explore the diagnosis and management of squamous cell carcinoma of the anus.

关键词： Anal cancer Squamous cell cancer Nigro protocol Anal intraepithelial neoplasia Chemoradiation therapy Anal neoplasm Radiotherapy Cancer screening Drug therapy

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Sonochemical Decolorization of Methyl Orange in Aqueous Solution

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Journal of Donghua University(English Edition) 2006年第5期23卷 127-130页

作者：邢铁玲 Chu k.H. 陈国强 School of Material Engineering Soochow University Department of Chemical and Process Engineering University of Canterbury New Zealand

The sonochemical decolorization of Methylene Orange was studied using a 24 kHz Ultrasound device with a 1.4 cm diameter horn. pH, power density, the effects of pH and power density on decolorization were discussed. The combined effect of radiate time, the initial concentration of dyes and the addition of Fe^2＋ on the decolorization was studied using response surface methodology. The results showed that the factorial central composite design was successfully employed for experimental design and predication of the results. AtpH = 2.8, T=30℃, power denstity= 300 W/L and Fe^2＋ of 2 mg/L, the decolorization percentage of 5 mg/L dye solution reached 96% after 60 mill ultreatment. The rate of decolorization of the dye was greatly improved in the presence of Fe^2＋. The sonolysis of the dye followed first-order kinetics.

关键词： sonochemical methyl orange dyes decolorization response surface methodology.

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Management of metabolic-associated fatty liver disease: The diabetology perspective

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World Journal of Gastroenterology 2023年第1期29卷 126-143页

作者： Mohammad Sadiq Jeeyavudeen Shahanas k A khan Sherouk Fouda Joseph M Pappachan Department of Endocrinology and Metabolism University Hospitals of EdinburghEdinburgh EH42XUUnited Kingdom Department of Endocrinology and Metabolism Lancashire Teaching Hospitals NHS TrustPreston PR29HTUnited Kingdom School of Health and Biomedical Sciences RMIT UniversityMelbourneVIC 3046Australia Faculty of Science Manchester Metropolitan UniversityManchester M156BHUnited Kingdom Faculty of Biology University of ManchesterManchester M139PLUnited Kingdom

The metabolic syndrome as a consequence of the obesity pandemic resulted in a substantial increase in the prevalence of metabolic-associated fatty live disease(MAFLD)and type 2 diabetes mellitus(T2DM).Because of the similarity in pathobiology shared between T2DM and MAFLD,both disorders coexist in many patients and may potentiate the disease-related outcomes with rapid progression and increased complications of the individual *** fact,awareness about this coexistence and the risk of complications are often overlooked by both hepatologists and *** of these individual disorders in a patient should be addressed wholistically using an appropriate multidisciplinary team approach involving both the specialists and,when necessary,liaising with dieticians and *** comprehensive review is to compile the current evidence from a diabetologist's perspective on MAFLD and T2DM and to suggest optimal management strategies.

关键词： Metabolic syndrome Metabolic-associated fatty liver disease Type 2 diabetes mellitus Nonalcoholic fatty liver disease Nonalcoholic steatohepatitis Diabetology perspective Obesity

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QSM-IDM -A novel quadrature spatial modulation based on interleaving division multiplexing for multiple antenna system

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Digital Communications and Networks 2019年第3期5卷 183-188页

作者： Sherif k. El Dyasti Esam A.A. Hagras Hadia El-Hennawy Ain Shams Cairo Egypt Elec and Comm. Dept Technical Research Centre Cairo Egypt Faculty of Engineering Ain Shams Cairo Egypt

Quadrature Spatial Modulation (QSM) is a high spectral efficiency Multiple-Input Multiple Output (MIMO) technique used to improve the spectral efficiency of wireless communication systems. The main concept of QSM is to extend the spatial constellation of the conventional Spatial Modulation (SM) in both the in-phase and quadrature components of the data symbol. In this paper, because QSM-based on Interleaxdng Division Multiplexing (IDM) has not been introduced in the literature as a multiple antenna system, we introduced a novel scheme, called QSM system based on Interleaving Division Multiplexing (QSM-IDM). The antenna sets are also applied to a spreader, before being used to assign an antenna number for information transmission. Analysis and simulations for a flat fading channel show that the proposed QSM-IDM method significantly outperforms the original QSM system with the same data rate, while maintaining a relatively acceptable complexity. The obtained simulation results show that the conducted analysis yields significant improvements for the accuracy of the proposed scheme, with satisfactory complexity.

关键词： Interleaver Division Multiplexing (IDM) Multiple Input Multiple Output (MIMO) Spatial Modulation (SM) Quadrature Spatial Modulation (QSM)

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Dynamic Active Noise Control of Broadband Noise in Fighter Aircraft Pilot Helmet

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Sound & Vibration 2022年第4期56卷 319-331页

作者： Y.k.Bharath S.Veena Malnad College of Engineering Hassan573202India National Aerospace Laboratories Bengaluru560017India

This paper presents the development of a dynamic Active Noise Control(ANC)algorithm aimed towards redu-cingthe broadbandnoiseinside the helmet earcups ofaﬁghter aircraftpilot *** dynamicANC involves a Variable Step-Size Grifﬁths(VSSG)FxLMS algorithm to attenuate noise entering directly through helmet,a LMS based adaptive noise canceller to attenuate noise entering through the pilot microphone,and energy detectors for failure protection and optimized battery power *** algorithms are implemented on Texas Instruments’TMS320C6748 processor and are tested in a helmet ANC experimental setup.

关键词： Active noise control Variable Step-Size Grifﬁths algorithm FxLMS

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AAV-based gene therapy approaches for genetic forms of tauopathies and related neurogenetic disorders

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BIOCELL 2022年第4期46卷 847-853页

作者： MOHAMED AGHYAD AL kABBANI GILBERT WUNDERLICH CHRISTOPH kÖHLER HANS ZEMPEL Faculty of Medicine and University Hospital Cologne Institute of Human GeneticsUniversity of CologneCologne50931Germany Faculty of Medicine and University Hospital Cologne Center for Molecular Medicine Cologne(CMMC)University of CologneCologne50931Germany Faculty of Medicine and University Hospital Cologne Department of NeurologyUniversity of CologneCologne50937Germany Faculty of Medicine and University Hospital Cologne Center for Rare DiseasesUniversity of CologneCologne50937Germany Faculty of Medicine and University Hospital Cologne Center AnatomyDepartment of Molecular and Translational NeuroscienceUniversity of CologneCologne50931Germany

Tauopathies comprise a spectrum of genetic and sporadic neurodegenerative diseases mainly characterized by the presence of hyperphosphorylated TAU protein aggregations in neurons or *** therapy,in particular adeno-associated virus(AAV)-based,is an effective medical approach for difficult-to-treat genetic diseases for which there are no convincing traditional therapies,such as *** AAV-based gene therapy to treat,in particular,genetic tauopathies has many potential therapeutic benefits,but also drawbacks which need to be addressed in order to successfully and efficiently adapt this still unconventional therapy for the various types of *** this Viewpoint,we briefly introduce some potentially treatable tauopathies,classify them according to their etiology,and discuss the potential advantages and possible problems of AAV-based gene ***,we outline a future vision for the application of this promising therapeutic approach for genetic and sporadic tauopathies.

关键词： Tauopathies Neurogenetic diseases AAV-based gene therapy Neurodegeneration Alzheimer disease TAU

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Effects of L-arginine and L-citrulline supplementation in reduced protein diets for broilers under normal and cyclic warm temperature

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Animal Nutrition 2021年第4期7卷 927-938页

作者： Hiep Thi Dao Nishchal k.Sharma Emma J.Bradbury Robert A.Swick School of Environmental and Rural Science Faculty of ScienceAgricultureBusiness and LawUniversity of New EnglandArmidaleAustralia Faculty of Animal Science Vietnam National University of AgricultureTrau Quy TownGia Lam DistrictHanoiViet Nam Ridley AgriProducts MelbourneVictoriaAustralia

Heat stress causes significant economic losses in the broiler *** supplementation of arginine(Arg)and citrulline(Cit)might increase the performance of broilers raised under warm temperature due to vasodilation *** study investigated the effects of L-Arg or L-Cit supplementation in broilers fed a reduced protein wheat-based diet deficient in Arg under thermoneutral(NT)and cyclic warm temperature(WT).Ross 308 cockerels(n=720)were randomly allocated to 4 dietary treatments with 12 replicates of 15 birds per pen from d 7 to *** 4 treatments were:normal protein(NP),i.e.,22.3%and 20.9%crude protein in grower and finisher,respectively;reduced protein(RP),i.e.,2.5%lower protein and deficient in Arg;and RP supplemented with 0.28%Arg(RP-Arg)or 0.28%Cit(RP-Cit).A factorial arrangement of treatments was applied during the finisher phase(21 to 35 d).Factors were:diet(4 diets above);and temperature,NT(24℃)or cyclic WT(33±1℃for 6 h per day)with 6 replicate pens per *** 7 to 35 d and 21 to 35 d,the birds fed the RP diet had lower body weight gain(BWG)and higher FCR compared to the NP diet(Pke(FI),lower BWG(P0.05)compared to birds exposed to *** by temperature interactions were not observed for performance parameters during the period of WT(P>0.05).On d 35,the RP-fed birds had a lower yield of thigh and drumstick,higher fat pad,lower femur ash,and breaking strength but similar serum uric acid level and higher nitrogen digestibility on d 21 compared to those offered NP(P<0.05).Supplementation of Arg or Cit to RP resulted in increased femur ash on d 35(P<0.05).Thus,feeding the NP diets is necessary to maintain growth performance in broilers regardless of the temperature conditions.

关键词： Arginine Citrulline Meat chickens Low protein Heat stress

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Systematic review of the prevalence and development of osteoporosis or low bone mineral density and its risk factors in patients with inflammatory bowel disease

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World Journal of Gastroenterology 2020年第35期26卷 5362-5374页

作者： Sofia kärnsund Bobby Lo Flemming Bendtsen Jakob Holm Johan Burisch Gastrounit Medical DivisionCopenhagen University Hospital HvidovreHvidovre 2650Denmark Department of Endocrinology Copenhagen University Hospital HerlevHerlev 4600Denmark

BACkGROUND The inflammatory bowel diseases(IBD),Crohn’s disease(CD)and ulcerative colitis(UC)are chronic,immune-mediated disorders of the digestive *** is considered to be a risk factor for developing osteoporosis;however current literature on this matter is *** To assess prevalence and development of osteoporosis and low bone mineral density(BMD),and its risk factors,in IBD *** Systematic review of population-based *** were identified by electronic(January 2018)and manual searches(May 2018).Databases searched included EMBASE and PubMed and abstracts from 2014-2018 presented at the United European Gastroenterology Week,the European Crohn’s and Colitis Organisation congress,and Digestive Disease Week were *** were eligible for inclusion if they investigated either the prevalence of osteoporosis or osteopenia and/or risk factors for osteoporosis or low BMD in IBD *** on children under the age of 18 were *** population-based studies were *** risk factors for osteoporosis and low BMD investigated in any included article were *** quality and the possibility of bias were analysed using the Newcastle-Ottawa *** Twelve studies including 3661 IBD patients and 12789 healthy controls were *** of osteoporosis varied between 4%-9%in studies including both CD and UC patients;2%-9% in studies including UC patients, and 7%-15% instudies including CD patients. Among healthy controls, prevalence ofosteoporosis was 3% and 10% in two studies. CD diagnosis, lower body massindex (BMI), and lower body weight were risk factors associated withosteoporosis or low BMD. Findings regarding gender showed inconsistent *** patients had an increased risk for osteoporosis or low BMD over time, whileUC patients did not. Increased age was associated with decreased BMD, and therewas a positive association between weight and BMI and BMD over time. Greatheterogeneity was

关键词： Inflammatory bowel disease Osteoporosis Systematic review Epidemiology Bone mineral density

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