Anal squamous cell carcinoma: An evolution in disease and management

作     者：Marc C Osborne Justin Maykel Eric K Johnson Scott R Steele 

作者机构：University of Minnesota Minneapolis MN55415 United States University of Massachusetts Memorial Medical Center Worcester MA 01609 United States Department of Surgery Madigan Army Medical Center Tacoma WA 98431 United States 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2014年第20卷第36期

页      面：13052-13059页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Anal cancer Squamous cell cancer Nigro protocol Anal intraepithelial neoplasia Chemoradiation therapy Anal neoplasm Radiotherapy Cancer screening Drug therapy 

摘      要：Anal cancer represents less than 1% of all new cancers diagnosed annually in the United States. Yet, despite the relative paucity of cases, the incidence of anal cancer has seen a steady about 2% rise each year over the last decade. As such, all healthcare providers need to be cognizant of the evaluation and treatment of anal squamous cell carcinoma. While chemoradiation remains the mainstay of therapy for most patients with anal cancer, surgery may still be required in recurrent, recalcitrant and palliative disease. In this manuscript, we will explore the diagnosis and management of squamous cell carcinoma of the anus.