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Outcomes of upper airway reconstructive surgery for obstructive sleep apnea syndrome based on polysomnography after nasopharyngeal tube insertion

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Chinese Medical Journal 2013年第24期126卷 4674-4678页

作者： LI Shu-hua WU Da-hai BAO ji-min shi Hong-jin Department of Otolaryngology-Head and Neck Surgery GeneralHospital of Shenyang Military Area Command Shenyang Liaoning110840 China Department of Otolaryngology-head and Neck Surgery Liaoning Jinqiu Hospital Shenyang Liaoning 110016 China

Background The most common obstruction sites for obstructive sleep apnea hypopnea syndrome （OSAHS） are the oropharynx and the glossopharyx. The diagnosis of glossopharyngeal airway obstruction is difficult. The study aimed to assess the effect of upper airway reconstructive surgery for OSAHS based on polysomnography （PSG） after nasopharyngeal tube insertion （NPT-PSG）, and to evaluate the clinical value of NPT-PSG in localizing the obstructive sites. Methods Seventy-nine OSAHS patients diagnosed with PSG were included in the study. PSG was repeated with a nasopharyngeal tube in place （NP＇r-PSG）. Results of the two PSGs were compared. A NPT-PSG apnea hypopnea index （AHI） greater than 15 times per hour was used as a threshold for glossopharyngeal surgery. The cause of glossopharyngeal airway obstruction was taken into consideration in planning glossopharyngeal surgery. Assessment of efficacy was followed-up. Results After NPT-PSG, patients＇ AHI significantly decreased and lowest oxygen saturation （LaSO2） significantly increased. Of the 79 patients, 47 were treated with uvulopalatopharyngoplasty （UPPP） alone and 32 with UPPP ＋ glossopharyngeal surgery. Thirty-two patients were considered cured, 33 markedly improved, and 14 failed. The overall surgery success rate was 82.3%. Conclusions NPT-PSG can be used as a diagnosis tool for localizing airway obstruction in OSAHS patients. Surgical treatment based on NPT-PSG results in good treatment efficacy.

关键词： obstructive sleep apnea hypopnea syndrome, nasopharyngeal tube, polysomnography surgery

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Extrahepatic bile duct reconstruction in pigs with heterogenous animal-derived artificial bile ducts:A preliminary experience

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World Journal of Gastroenterology 2020年第46期26卷 7312-7324页

作者： hao Shang jian-Ping Zeng Si-Yuan Wang Ying Xiao jiang-Hui Yang Shao-Qing Yu Xiang-Chen Liu Nan jiang Xia-Li shi Shuo jin Department of Hepatopancreatobiliary Surgery Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijing 102200China Department of Pathology Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijing 102200China Institute for Precision Medicine Tsinghua University Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijing 102218China Department of Anesthesiology and Operation The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710004Shaanxi ProvinceChina

BACKGROUND Extrahepatic biliary duct injury(BDI)remains a complicated issue for *** several approaches have been explored to address this problem,the high incidence of complications affects postoperative *** a nonimmunogenic scaffold,an animal-derived artificial bile duct(ada-BD)could replace the defect,providing good physiological conditions for the regeneration of autologous bile duct structures without changing the original anatomical and physiologic *** To evaluate the long-term feasibility of a novel heterogenous ada-BD for treating extrahepatic BDI in *** Eight pigs were randomly divided into two groups in the *** animal injury model was developed with an approximately 2 cm segmental defect of various parts of the common bile duct(CBD)for all pigs.A 2 cm long novel heterogenous animal-derived bile duct was used to repair this segmental defect(group A,ada-BD-to-duodenum anastomosis to repair the distal CBD defect;group B,ada-BD-to-CBD anastomosis to repair the intermedial CBD defect).The endpoint for observation was 6 mo(group A)and 12 mo(group B)after the *** function was regularly *** were euthanized at the above *** analysis was carried out to assess the efficacy of the *** The median operative time was 2.45 h(2-3 h),with a median anastomosis time of 60.5 min(55-73 min).All experimental animals survived until the endpoints for *** liver function was almost *** analysis indicated a marked biliary epithelial layer covering the neo-bile duct and regeneration of the submucosal connective tissue and smooth muscle without significant signs of immune *** comparison,the submucosal connective tissue was more regular and thicker in group B than in group A,and there was superior integrity of the regeneration of the biliary epithelial *** the advantages of the regeneration of the bile duct smooth muscle observed in group A,th

关键词： Bile duct injury Animal-derived artificial bile duct Heterogenous ureteral graft Nonimmunogenic Bile duct reconstruction Common bile duct

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丝胶蛋白/再生聚酯沉析纤维的制备及其性能研究

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江西化工 2024年第1期40卷 88-91页

作者：方施颖王振宇汪浩祥张卫民牟铭蔡玉荣浙江理工大学浙江杭州310018 绍兴诚邦高新纤维科技有限公司浙江绍兴312000 浙江理工大学绍兴柯桥研究院有限公司浙江绍兴312030

利用沉析法制备再生聚酯短纤维,并研究丝胶蛋白添加量及剪切速度对所制备沉析纤维形貌、结晶度、亲水性、回潮率等的影响。结果表明:利用沉析法可以制得丝胶蛋白/再生聚酯短纤,纤维呈丝带状,形态柔顺,质轻且薄。添加丝胶蛋白及提高剪切... 详细信息

利用沉析法制备再生聚酯短纤维,并研究丝胶蛋白添加量及剪切速度对所制备沉析纤维形貌、结晶度、亲水性、回潮率等的影响。结果表明:利用沉析法可以制得丝胶蛋白/再生聚酯短纤,纤维呈丝带状,形态柔顺,质轻且薄。添加丝胶蛋白及提高剪切速度可以有效改善纤维的亲水性和回潮率,当丝胶蛋白添加量为15%,且剪切速度为9000r/min时,沉析纤维的水接触角为45.2°,回潮率为3.47%,表现出优秀且持久的吸湿性能。

关键词：再生聚酯沉析纤维亲水性丝胶蛋白

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氩等离子体射流对聚四氟乙烯表面改性的研究

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西安交通大学学报 2014年第4期48卷 59-67页

作者：郝致远汲胜昌宋莹西安交通大学电力设备电气绝缘国家重点实验室西安710049

采用氩等离子体射流对有机材料聚四氟乙烯(PTFE)进行表面改性,通过接触角测量、扫描电子显微镜(SEM)观察、X射线光电子能谱(XPS)和衰减全反射红外光谱(ATR-FTIR)分析,以及表面电阻率和沿面闪络电压等参量的测量,研究了等离子体射流处理... 详细信息

采用氩等离子体射流对有机材料聚四氟乙烯(PTFE)进行表面改性,通过接触角测量、扫描电子显微镜(SEM)观察、X射线光电子能谱(XPS)和衰减全反射红外光谱(ATR-FTIR)分析,以及表面电阻率和沿面闪络电压等参量的测量,研究了等离子体射流处理前后PTFE的表面特性。实验结果表明:氩等离子体射流产生的粒子主要有OH、N*、Ar和少量的O。PTFE经大气压氩等离子体射流处理后,其表面水接触角下降,表面粗糙度变大,表面突起和裂痕显著增加,且表面有新的含氧基团生成;增加表面改性时间,表面改性效果会达到饱和状态;另一方面,表面改性后的PTFE存在微弱的老化效应,当在空气中放置10d后,其表面水接触角为66.2°,仍然低于表面处理前的值。由于等离子体改性使PTFE表面形态及化学成分发生变化,粗糙度增加,使PTFE表面电阻率降低,导致其沿面闪络电压升高。

关键词：等离子体射流表面改性聚四氟乙烯水接触角闪络电压

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Parametric amplification of Rydberg six- and eight-wave mixing processes

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Photonics Research 2018年第7期6卷 713-720页

作者： ZhaoYANG ZHANG ji GUO BINGLING GU LING hao GAOGUO YANG KUN WANG YANPENG ZHANG Key Laboratory for Physical Electronics and Devices of the Ministry of Education & Shaanxi Key Laboratory of Information Photonic Technique Xi’an Jiaotong University

We study the parametric amplification of electromagnetically induced transparency-assisted Rydberg six-and eight-wave mixing signals through a cascaded nonlinear optical process in a hot rubidium atomic ensemble both theoretically and experimentally. The shift of the resonant frequency(induced by the Rydberg–Rydberg interaction) of parametrically amplified six-wave mixing signal is observed. Moreover, the interplays between the dressing effects and Rydberg–Rydberg interactions in parametrically amplified multiwave mixing signals are investigated. The linear amplification of Rydberg multiwave mixing processes with multichannel nature acts against the suppression caused by Rydberg–Rydberg interaction and dressing effect.

关键词：热铷原子系综电磁诱导通讯技术发展现状

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小麦新品种品育8012白粉病抗性研究

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陕西农业科学 2024年第4期70卷 85-89,95页

作者：郝建宇马小飞李晓丽张洋杨镕兆姜兰芳曹勇王敏姬虎太山西农业大学小麦研究所山西临汾041000

品育8012是由山西农业大学小麦研究所选育,2018年通过山西省审定,亲本组合临优20165/济麦22,2020-2022年连续三年被列为山西省农业生产主推品种,该品种近免疫白粉病。为了解品育8012白粉病抗性,先进行亲本已知抗病基因检测,继而进行其... 详细信息

品育8012是由山西农业大学小麦研究所选育,2018年通过山西省审定,亲本组合临优20165/济麦22,2020-2022年连续三年被列为山西省农业生产主推品种,该品种近免疫白粉病。为了解品育8012白粉病抗性,先进行亲本已知抗病基因检测,继而进行其它抗病基因检测,随后在山西、山东和河北3省15点田间鉴定进行验证试验。得出品育8012携带13个白粉病抗性基因,在山西、山东和河北多点对白粉病表现中抗乃至近免疫。品育8012可作为选育抗白粉病小麦品种的抗源加以利用。

关键词：品育8012 白粉病抗性基因检测

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Enhancement-Mode InAlAs/InGaAs/InP High Electron Mobility Transistor with Strained InAlAs Barrier Layer

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Chinese Physics Letters 2000年第8期17卷 619-620页

作者： AO jin-Ping ZENG Qing-Ming Zhao Yong-Lin LI Xian-jie LIU Wei-ji LIU shi-Yong LIANG Chun-guang Hebei Semiconductor Research Institute Shijiazhuang 050051 National Integrated Optoelectronics Laboratory Jilin UniversityChangchun 130023

The relatively low Schottky barrier height on In_(0.52)Al_(0.48)As lattice-matched to InP has hampered the achievement of enhancement-mode InA1As/InGaAs/InP high electron mobility transistors(E-HEMTs).By introducing lattice mismatched strained aluminum-rich In_(0.45) Al_(0.55)As as the Schottky contact material to enhance the barrier height,we have developed InP-based InAlAs/InGaAs/InP E-HEMT with threshold voltage of about 150 m V.A maximum extrinsic transconductance of 660mS/mm and output conductance of 15mS/mm are measured for 1μm-gate length devices at room *** devices also show excellent radio-frequency performance with cutoff frequency of 50 GHz and maximum oscillation frequency of 54 GHz.

关键词： temperature. Schottky HEMTs

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区域协调发展中县(市)域发展规划的实践与启示——论陈烈的县域发展规划的实践特点

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经济地理 2007年第2期27卷 275-278,284页

作者：王世豪广东外语外贸大学区域与城市经济研究所中山大学城市与区域规划系中国广东广州510275

对陈烈的县域发展规划的实践特点作了归纳总结。同时认为,县(市)域发展规划是解决区域发展问题的重要切入点,有利于促进区域内及区域之间的协调发展。县(市)域发展规划的核心是调控人地关系,实现县域可持续发展。县(市)域发展规划论证... 详细信息

对陈烈的县域发展规划的实践特点作了归纳总结。同时认为,县(市)域发展规划是解决区域发展问题的重要切入点,有利于促进区域内及区域之间的协调发展。县(市)域发展规划的核心是调控人地关系,实现县域可持续发展。县(市)域发展规划论证了“人地关系地域系统”理论的实践价值;使区域发展理论的应用价值得到提高。

关键词：县(市)域规划区域协调发展可持续发展人地关系

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Origanum vulgare *** extract alleviates finasteride-induced oxidative stress in mouse liver and kidney

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Asian Pacific Journal of Tropical Biomedicine 2021年第5期11卷 194-204页

作者： Qi-Feng Sun shi-Xiang Chen Zhang-Feng Tang Xiao-Yi Song Fa jing hao-Tian Wu Zhong-Yang Ding Attalla El-kott Diaa Massoud Heba Khalifa Department of Hepatobiliary and Vascular Surgery Jinan City People's HospitalJinanShandong Province271100China Department of Hepatology Zhejiang University Ming Zhou HospitalNingboZhejiang Province315199China Department of General Surgery Wuxi Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Traditional Chinese MedicineWuxiJiangsu Province214023China Biology Department College of ScienceKing Khalid UniversityAbhaSaudi Arabia Zoology Department College of ScienceDamanhour UniversityDamanhourEgypt Biology Department College of ScienceJouf UniversityP.O.Box 2014SakakaAl-JoufSaudi Arabia Zoology Department Faculty of ScienceFayoum UniversityFayoumEgypt

Objective:To investigate the hepatorenoprotective effects of Origanum vulgare *** finasteride-induced oxidative injury in the liver and kidney of ***:Liquid chromatography-electrospray ionization-tandem mass spectrometry(LC-ESI/MS)analysis was utilized to yield a fingerprint of Origanum vulgare polyphenolic *** BALB/c mice received 0.5 mL/day distilled water,finasteride(25 mg/kg/day for 10 d),and 100,200,or 400 mg/kg/day finasteride+Origanum vulgare extract with 6 mice per group for five *** day 36,liver and kidney function as well as pro-and antiinflammatory(IFN-γ,IL-12,IL-6,TNF-α,IL-1β,and IL-10)cytokines were *** total antioxidant status,nitric oxide(NO),and malondialdehyde levels as well as the activities of NO synthase and catalase were also *** study was conducted to assess the effect of Origanum vulgare extract on finasteride-induced renal and hepatic ***:Twenty-five major polyphenolic compounds were identified in the Origanum vulgare extract by LC-ESI/*** vulgare extract,especially at 200 and 400 mg/kg/day doses,significantly improved liver and kidney biochemical indices,decreased inflammatory cytokines,increased total antioxidant status and NO synthase and catalase activities,as well as decreased plasma NO and malondialdehyde levels in a dose-dependent manner as compared to the finasteride *** results further confirmed the protective effect of Origanum vulgare ***:Origanum vulgare extract ameliorates finasterideinduced hepatic and renal biochemical and histopathological alterations,and restores antioxidant/oxidant balance.

关键词： Kidney Liver Origanum vulgare L. Inflammation Antioxidant

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草鱼nrf1基因的克隆与表达及其应激响应研究

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水生生物学报 2024年第3期48卷 461-468页

作者：莫郁坚易成琳肖扬波杨立权宋世航湛瑞杰夏浩云孙琳周罗璟瞿符发唐建洲刘臻曹申平长沙学院生物与化学工程学院水生动物营养与品质调控湖南省重点实验室长沙410022

为研究跨膜转录因子核因子E2相关因子1(Nuclear factor-erythroid 2 related factor 1,nrf1)在动物机体抗氧化应激过程中的作用,通过同源克隆获得草鱼nrf1基因序列,其开放阅读框为1560 bp,编码519个氨基酸;系统进化树分析表明草鱼nrf1... 详细信息

为研究跨膜转录因子核因子E2相关因子1(Nuclear factor-erythroid 2 related factor 1,nrf1)在动物机体抗氧化应激过程中的作用,通过同源克隆获得草鱼nrf1基因序列,其开放阅读框为1560 bp,编码519个氨基酸;系统进化树分析表明草鱼nrf1与团头鲂(Megalobrama amblycephala)进化关系较近。对nrf1进行组织表达分析,结果显示nrf1在肝脏中表达水平最高,其次是心脏和肠道(P<0.05)。昼夜节律分析显示,在9:00时nrf1表达水平最高且显著高于3:00、12:00、18:00、21:00和24:00(P<0.05)。经急性氨氮胁迫处理24h和48h时,发现草鱼nrf1基因在低氨氮(5 mg/L)组和高氨氮(20 mg/L)组中表达量相对于对照组均显著升高(P<0.05);且低氨氮组nrf1表达量在24h时显著低于高氨氮组(P<0.05),而在48h时显著高于高氨氮组(P<0.05)。此外,研究使用3种不同蛋白源(鱼粉、菜粕和豆粕)饲料对草鱼进行生长实验,发现在养殖后14d、28d和35d,菜粕和豆粕组nrf1表达水平显著高于鱼粉组(P<0.05),其中28d时豆粕组nrf1表达量显著高于菜粕组(P<0.05)。综上所述,草鱼nrf1基因表达具有组织特异性,且受到水体氨氮浓度和饲料蛋白源的调控,研究为揭示鱼类nrf1基因的分子特征及其抗氧化应激反应中的功能奠定了理论基础。

关键词： nrf1 基因克隆氨氮胁迫蛋白源应激反应草鱼

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