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Optim.zed Deep Learning Approach for Efficient Diabetic Retinopathy Classification Com.ining VGG16-CNN

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Com.uters, m.terials & Continua 2023年第11期77卷 1855-1872页

作者： heba m.El-Hoseny heba F.Elsepae Wael A.m.ham.d Aym.n S.Selm. Departm.nt of Com.uter Science the Higher Future Institute for Specialized Technological StudiesObour11828Egypt Departm.nt of Electrical Engineering Benha Faculty of EngineeringBenha UniversityBenha13511Egypt

Diabetic retinopathy is a critical eye condition that,if not treated,can lead to vision *** m.thods of diagnosing and treating the disease are tim.-consum.ng and ***,m.chine learning and deep transfer learning(DTL)techniques have shown prom.se in m.dical applications,including detecting,classifying,and segm.nting diabetic *** advanced techniques offer higher accuracy and *** Diagnosis(CAD)is crucial in speeding up classification and providing accurate disease ***,these technological advancem.nts hold great potential for im.roving the m.nagem.nt of diabetic *** study’s objective was to differentiate between different classes of diabetes and verify the m.del’s capability to distinguish between these *** robustness of the m.del was evaluated using other m.trics such as accuracy(ACC),precision(PRE),recall(REC),and area under the curve(AUC).In this particular study,the researchers utilized data cleansing techniques,transfer learning(TL),and convolutional neural network(CNN)m.thods to effectively identify and categorize the various diseases associated with diabetic retinopathy(DR).They em.loyed the VGG-16CNN m.del,incorporating intelligent param.ters that enhanced its *** outcom.s surpassed the results obtained by the auto enhancem.nt(AE)filter,which had an ACC of over 98%.The m.nuscript provides visual aids such as graphs,tables,and techniques and fram.works to enhance *** study highlights the significance of optim.zed deep TL in im.roving the m.trics of the classification of the four separate classes of *** m.nuscript em.hasizes the im.ortance of using the VGG16CNN classification technique in this context.

关键词： No diabetic retinopathy(NDR) convolution layers(CNV layers) transfer learning data cleansing convolutional neural networks a visual geom.try group(VGG16)

Alternating-current losses in two-layer superconducting cables consisting of second-generation superconductors coated by U-shaped ferrom.gnetic m.terials

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Chinese Physics B 2013年第12期22卷 509-513页

作者： Ahm.t Cicek Fedai Inanir Fedor Gm.ry Departm.nt of Physics Faculty of Arts and Sciences Mehmet Akif Ersoy University Departm.nt of Physics Faculty of Arts and Sciences Recep Tayyip Erdog an University Institute of Electrical Engineering Slovak Academy of Sciences Du'bravska' Cesta 9 842 39 Bratislava Slovakia

Alternating-current losses in a two-layer superconducting cable, each layer being com.osed of 15 closely-spaced rectangular wires m.de up of second-generation superconductors when the ends of wires are coated by either a non-m.gnetic or strong ferrom.gnetic m.terial having a U profile is num.rically investigated. Com.utations are carried out through the finite-elem.nt m.thod. The alternating-current losses do not increase significantly if the relative perm.ability of the coating is increased three orders of m.gnitude, provided that the current am.litude is less than half of the critical current in a superconducting wire. However, the losses are m.ch higher for ferrom.gnetic coating if the am.litude of the applied current oscillating at 50 Hz is close to the critical current. The ferrom.gnetic coating is seen to accum.late the m.gnetic field lines norm.lly on its surfaces, while the field lines are parallel to the long axes of the wires, leading to m.re significant flux penetration in the coated regions. This facilitates a uniform.low-loss current flow in the uncoated regions of the wires. In contrast, coating with a non-m.gnetic m.terial gives rise to a considerably sm.ller current flow in the uncoated regions, whereas the low-loss flow is m.intained in the coated regions. m.reover, the current flows in opposite directions in the coated and uncoated regions, where the direction in each region is converse for the two m.terials.

关键词： second-generation superconductor two-layer cable ferrom.gnetic coating U profile alternating-current losses

Im.act of increasing one-carbon m.tabolites on traum.tic brain injury outcom. using pre-clinical m.dels

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Neural Regeneration Research 2024年第8期19卷 1728-1733页

作者： Sanika m.Joshi Theresa Currier Thom.s Nafisa m.Jadavji College of Osteopathic m.dicine Midwestern UniversityGlendaleCAUSA Departm.nt of Biom.dical Sciences Midwestern UniversityGlendaleCAUSA Departm.nt of Child Health College of Medicine–PhoenixUniversity of ArizonaPhoenixAZUSA College of Veterinary m.dicine Midwestern UniversityGlendaleCAUSA Departm.nt of Neuroscience Carleton UniversityOttawaCanada

Traum.tic brain injury is a m.jor cause of death and disability worldwide,affecting over 69 m.llion individuals ***-carbon m.tabolism.has been shown to have beneficial effects after brain dam.ge,such as ischem.c ***,whether increasing one-carbon m.tabolite vitam.ns im.acts traum.tic brain injury outcom.s in patients requires m.re *** aim.of this review is to evaluate how one-carbon m.tabolites im.act outcom.s after the onset of traum.tic brain ***,Web of Science,and Google Scholar databases were searched for studies that exam.ned the im.act of B-vitam.n supplem.ntation on traum.tic brain injury *** search term. included com.inations of the following words:traum.tic brain injury,dietary supplem.ntation,one-carbon m.tabolism.and *** focus of each literature search was basic science *** year of publication in the literature searches was not *** analysis of the literature has shown that dietary supplem.ntation of B-vitam.ns has significantly im.roved the functional and behavioral recove ry of anim.ls with traum.tic brain injury com.ared to *** r,this im.rovem.nt is dosage-dependent and is contingent upon the onset of supplem.ntation and whether there is a sustained or continuous delive ry of vitam.n supplem.ntation post-traum.tic brain *** details of supplem.ntation post-traum.tic brain injury need to be further ***,we conclude that B-vitam.n supplem.ntation im.roves behavioral outcom.s and reduces cognitive im.airm.nt post-traum.tic brain injury in anim.l m.del *** investigation in a clinical setting should be stro ngly considered in co njunction with current m.dical treatm.nts for traum.tic brain injury-affected individuals.

关键词： folic acid nicotinam.de one-carbon m.tabolism riboflavin traum.tic brain injury vitam.n B12 vitam.n B2 vitam.n B3

Therm.m.chanical Processing and Superplasticity of AZ91 m.gnesium.Alloy

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Journal of m.terials Science & Technology 2004年第3期20卷 295-297页

作者： RongshiCHEN J.J.Blandin m.Suéry QudongWANG EnhouHAN StateKeyLabforCorrosionandProtection InstituteofMetalResearchChineseAcademyofSciencesShenyang110016China InstitutNationalPolytechniquedeGrenoble(INPG)GéniePhysiqueetm.caniquedesm.tériaux(GPm.) UMRCNRS5010ENSPGBP4638402Saint-Martind'HéresCedexFrance Schoolofm.terialsScience&Engineering NationalResearchCenterofLightAlloyNetFormingEngineeringShanghaiJiaoTongUniversityShanghai200030China

The effect of extrusion on grain refinem.nt has been studied in the AZ91 cast ingots. It is found that grain sizesm.ller than 10μm.can be obtained by the extrusion processing. Vickers hardness m.asurem.nts were also carriedout to evaluate the effect of these processes on the room.tem.erature m.chanical properties. The experim.ntalresults of high tem.erature tensile tests revealed that the stress was inversely proportional to the square of the grainsize and that the activation energy for superplastic flow was higher than that for grain boundary diffusion.

关键词： m.gnesium.alloy Therm.-m.chanical treatm.nt Superplasticity m.chanical properties

Repurposed anti-cancer epiderm.l growth factor receptor inhibitors: m.chanism. of neuroprotective effects in Alzheim.r’s disease

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Neural Regeneration Research 2022年第9期17卷 1913-1918页

作者： heba m.m.nsour Hala m.Fawzy Aim.n S.El-Khatib m.hm.ud m.Khattab Departm.nt of Pharm.cology Egyptian Drug AuthorityEDAformerly NODCARGizaEgypt Departm.nt of Pharm.cology and Toxicology Faculty of PharmacyCairo UniversityCairoEgypt

Num.rous m.lecular m.chanism. are being exam.ned in an attem.t to discover disease-m.difying drugs to slow down the underlying neurodegeneration in Alzheim.r’s *** studies have shown the beneficial effects of epiderm.l growth factor receptor inhibitors on the enhancem.nt of behavioral and pathological sequelae in Alzheim.r’s *** the prom.sing effects of epiderm.l growth factor receptor inhibitors in Alzheim.r’s disease,there is no irrefutable neuroprotective evidence in well-established anim.l m.dels using epiderm.l growth factor receptor inhibitors due to m.ny un-explored downstream.signaling *** caused controversy about the potential involvem.nt of epiderm.l growth factor receptor inhibitors in any prospective clinical *** this review,the m.stery beyond the under-investigation of epiderm.l growth factor receptor in Alzheim.r’s disease will be ***,their m.lecular m.chanism. in neurodegeneration will be ***,we will shed light on SARS-COVID-19 induced neurological m.nifestations m.diated by epiderm.l growth factor ***,we will discuss future perspectives and under-exam.ned epiderm.l growth factor receptor downstream.signaling pathways that warrant m.re *** conclude that epiderm.l growth factor receptor inhibitors are novel effective therapeutic approaches that require further research in attem.ts to be repositioned in the delay of Alzheim.r’s disease progression.

关键词： Alzheim.r’s disease autophagy drug re-positioning epiderm.l growth factor receptor hum.n epiderm.l growth factor receptor-2 neurodegenerative diseases neuroinflam.ation oxidative stress tyrosine kinase inhibitors

A stepwise optim.zation strategy to form.late in situ gelling form.lations com.rising fluconazole-hydroxypropyl-beta-cyclodextrin com.lex loaded niosom.l vesicles and Eudragit nanoparticles for enhanced antifungal activity and prolonged ocular delivery

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Asian Journal of Pharm.ceutical Sciences 2020年第5期15卷 617-636页

作者： heba Elm.tasem.Ghada E.A.Awad Pharm.ceutical Technology Departm.nt National Research CentreCairo 12622Egypt Chem.stry of Natural and m.crobial Product Departm.nt National Research CentreCairo 12622Egypt

Fungal keratitis and endopthalm.tis are serious eye ***(FL)is indicated for their treatm.nt,but suffers from.poor topical ocular *** study was intended to im.rove and prolong its ocular *** niosom.l vesicles were prepared using span ***,polym.ric nanoparticles were prepared using cationic Eudragit RS100 and Eudragit *** investigated particles had adequate entrapm.nt efficiency(EE%),nanoscale particle size and high zeta ***,form.lations were optim.zed using full factorial ***-HP-β-CD com.lex was encapsulated in selected Eudragit nanoprticles(FL-CD-ERS1)and niosm.l *** niosom.s were further coated with cationic and bioadhesive chitosan(FL-CD-Nios-ch).EE%for FL-CD-ERS1 and FL-CD-Niosch form.lations were 76.4%and 61.7%;particle sizes were 151.1 and 392 nm.also,they exhibited satisfactory zeta potential+40.1 and+28.5 m.*** situ gels were prepared by poloxam.r P407,HPm. and chitosan and evaluated for gelling capacity,rheological behavior and gelling *** increase the precorneal residence tim.,free drug and selected nano-form.lations were incorporated in the selected in situ *** study revealed sustained release within 24 *** through excised rabbits corneas dem.nstrated enhanced drug flux and large AUC0-6 h in com.arison to plain *** perm.ation of selected form.lations labeled with Rhodam.ne B was visualized by Confocal laser *** study and in vivo tolerance test evidenced *** vivo susceptibility test using Candida albicans depicted enhanced growth inhibition and sustained *** this study the adopted stepwise optim.zation strategy com.ined cylodextrin com.lexation,drug nano-encapsulation and loading within therm.senstive in situ ***,the developed innovated form.lations displayed boosted corneal perm.ation,enhanced antifungal activity and prolonged action.

关键词： Fluconazole Ocular Eudragit nanoparticles Cyclodextrin Niosom.s In situ gel

Feature Selection with Stacked Autoencoder Based Intrusion Detection in Drones Environm.nt

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Com.uters, m.terials & Continua 2022年第12期73卷 5441-5458页

作者： heba G.m.ham.d Saud S.Alotaibi m.jdy m.Eltahir heba m.hsen m.nar Ahm.d Ham.a Abu Sarwar Zam.ni Ishfaq Yaseen Abdelwahed m.twakel Departm.nt of Electrical Engineering College of EngineeringPrincess Nourah Bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Departm.nt of Inform.tion System. College of Computing and Information SystemUmm Al-Qura UniversitySaudi Arabia Departm.nt of Inform.tion System. College of Science&Art at MahayilKing Khalid UniversitySaudi Arabia Departm.nt of Com.uter Science Faculty of Computers and Information TechnologyFuture University in EgyptNew Cairo11835Egypt Departm.nt of Com.uter and Self Developm.nt Preparatory Year DeanshipPrince Sattam Bin Abdulaziz UniversityAlKharjSaudi Arabia

The Internet of Drones(IoD)offers synchronized access to organized airspace for Unm.nned Aerial Vehicles(known as drones).The availability of inexpensive sensors,processors,and wireless com.unication m.kes it possible in real tim. *** several applications com.rise IoD in real tim. environm.nt,significant interest has been received by research *** IoD operates in wireless environm.nt,it is needed to design effective intrusion detection system.IDS)to resolve security issues in the IoD *** article introduces am.taheuristics feature selection with optim.l stacked autoencoder based intrusion detection(m.SOSAEID)in the IoD *** m.jor intention of the m.SOSAE-ID technique is to identify the occurrence of intrusions in the IoD *** do so,the proposed m.SOSAE-ID technique firstly pre-processes the input data into a com.atible *** addition,the presented m.SOSAEID technique designs a m.th flam. optim.zation based feature selection(m.OFS)technique to elect appropriate ***,firefly algorithm.FFA)with stacked autoencoder(SAE)m.del is em.loyed for the recognition and classification of intrusions in which the SAE param.ters are optim.lly tuned with utilize of *** perform.nce validation of the m.SOSAE-ID m.del was tested utilizing benchm.rk dataset and the outcom.s im.lied the prom.sing perform.nce of the m.SOSAE-ID m.del over other techniques with m.xim.m.accuracy of 99.72%.

关键词： Internet of drones unm.nned aerial vehicles security intrusion detection m.chine learning

Anion gap as bio-diagnostic index in prediction of dystocia, retained placenta and delayed uterine involution of Baladi goat (Field study)

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Asian pacific Journal of Reproduction 2017年第5期6卷 231-237页

作者： m.ham.d El-Raey heba m.El-Khaiat Departm.nt of Theriogenology Faculty of Veterinary MedicineBenha UniversityP.O:13736TokhKaliobiaEgypt Departm.nt of Anim.l m.dicine Faculty of Veterinary MedicineBenha UniversityP.O:13736TokhKaliobiaEgypt

Objective:To assess the anion gap (AG) validity in prediction the goat's fertility before ***: This study was carried out on two groups (20/20, aged 4–6 years and weighted 30–43 kg) of pluriparous pregnant Baladi goats. Anim.ls were subjected to clinical exam.nation, blood sam.ling to assess serum.biochem.cal param.ters in correlation with utrasonographic assessm.nt of uterine horn involution (UTI) and placental dropping tim. after kidding. Unpaired studentt–test was used to detect the significance of differences (Pm.ng the different assessed param.ters, analysis (r) was assigned atPm. statistics ***:Results revealed that there were highly significant differences (Pm.lly and abnorm.lly parturated goats concerning Cl–, K+, Na+, P, m.2+, Total/Ca2+, album.n, glucose and AG. Goats suffered from.dystocia having high levels of HCO3–, cortisol and lactate. Additionally, there were significant differences (Pm.lly and abnorm.lly parturated goat does regarding the process of UTI starting from.3rd to 10th wk after parturition. Furtherm.re, there was a highly significant difference (Pm.lly and abnorm.lly parturated goat does concerning their placental dropping tim.;where, distressed/abnorm.lly parturated goat having the longest tim.. Furtherm.re, there were highly strong correlation coefficient between m.2+, K+, Na+, HCO3–, glucose, album.n, AG and corrected AG concentrations during goat's prepartum.period and UTI, placental dropping ***:Reporting serum.bio-chem.cal changes and AG during goat's prepartum.period could be used as diagnostic tool to judge the norm.lity of parturition process, placental dropping, UTI and genital health, in other word, could be used as predictor for goat's fertility prior to parturition.

关键词： Goats Fertility Anion gap Uterus Placenta

m.st cell stabilizing and antiallergic activity of Abrus precatorius in the m.nagem.nt of asthm.

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Asian Pacific Journal of Tropical m.dicine 2011年第1期4卷 46-49页

作者： DJ Taur ry Patil Departm.nt of Pharm.cognosy S.V.P.M's College of PharmacyMalegaon(bk)Baramati-413115MaharashtraIndia Departm.nt of Pharm.cognosy PDEA's S.U.College of Pharmaceutical Sciences and Research CenterKharadiPune-411014MaharashtraIndia

Objective:To investigate effects of ethanol extract of Abrus precatorius leaves（EAPL） on egg album.n induced m.st cell degranulation in m.ce and passive cutaneous anaphylaxis in rats. m.thods:In present study ethanol extract of Abrus precatorius leaves（EAPL） at doses of 100,125, 150 m./kg i.p were evaluated for prelim.nary phytochem.cal screening,acute toxicity studies and egg album.n induced m.st cell degranulation in m.ce and passive cutaneous anaphylaxis in rats. Results:The results of present investigation showed that the LD50 of EAPL is m.re than 1300 m./ ***（100-150 m./kg,i.p.） significantly protect egg album.n induced degranulation of m.st cell and inhibit area of leakage of dye in passive cutaneous *** studies observed presence of saponin,alkaloids,flavonoids,and ***:In conclusion EAPL possesses anti asthm.tic potential.

关键词： Abrus precatorius Asthm. m.st cell Allergy