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Ileocecal intussusception caused by two different tumors - which is the culprit lesion? A case report

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World Journal of Clinical Cases 2020年第10期8卷 2044-2049页

作者： Wu-feng fan Gang Ma Gui-Chen Li Jin Long Yuan-Hong Xu Ke-Jian Guo Zhe Liu Department of Pancreatic-Biliary Surgery First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina

BACKGROUND Ileocecal intussusception caused by two different tumors is rare,according to a literature *** describe a case of a male patient with a cauliflower-like mass in the middle of the transverse colon observed by colonoscopy before *** was considered to be intussusception caused by colon ***,a substantial lipomatous mass was seen in the distal end of the intussusception by computed tomography before surgery,which posed a challenge in the preoperative *** SUMMARY We report a 72-year-old male patient with *** patient underwent right hemicolectomy and cholecystectomy in our hospital on April 29,*** operation,the ileum was inserted into the ascending colon by about 15 cm,and a tumor with a diameter of approximately 3.0 cm was observed in the distal part of the *** atypical liposarcoma/highly differentiated liposarcoma in the adipose tissue was suspected in the postoperative pathology,and a lipoma was diagnosed after MDM2 gene testing.A 4.0 cm×5.0 cm polypoid mass was seen immediately adjacent to the mass,and the postoperative pathology report suggested a high-level tubular *** patient was eventually cured and discharged with an uneventful *** Intussusception caused by two different types of masses is extremely *** present,surgery is the best treatment once intussusception is diagnosed.

关键词： Adult intussusception Two different tumors Right hemicolectomy and cholecystectomy Atypical liposarcoma High-level tubular adenoma Case report

CD98-induced CD147 signaling stabilizes the Foxp3 protein to maintain tissue homeostasis

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Cellular & Molecular Immunology 2021年第12期18卷 2618-2631页

作者： JieJie Geng Ruo Chen feng-fan Yang Peng Lin Yu-meng Zhu Xianghui Fu Ke Wang Zhuan feng Jiao Wu Hai Zhang Qi-jing Li Zhi-Nan Chen Ping Zhu Department of Clinical Immunology Xijing HospitalFourth Military Medical UniversityXi’anP.R.China National Translational Science Center for Molecular Medicine&Department of Cell Biology Fourth Military Medical UniversityXi’anP.R.China Department of Immunology Duke University Medical CenterDurhamNCUSA

Regulatory T cell(Treg)stability is necessary for the proper control of immune activity and tissue ***,it remains unclear whether Treg stability must be continually reinforced or is established during development under physiological ***3 has been characterized as a central mediator of the genetic program that governs Treg ***,we demonstrate that to maintain Foxp3 protein expression,Tregs require cell-to-cell contact,which is mediated by the CD147-CD98 *** Tregs are produced,CD147,which is expressed on their surface,is stimulated by CD98,which is widely expressed in the physiological *** a result,CD147’s intracellular domain binds to CDK2 and retains it near the membrane,leading to Foxp3 dephosphorylation and the prevention of Foxp3 *** addition,the optimal distribution of Foxp3+Tregs under both pathological and physiological conditions depends on CD98 ***,our study provides direct evidence that Foxp3-dependent Treg stability is reinforced in the periphery by the interaction between CD147 and CD98 in the surrounding *** importantly,Tregs with high CD147 expression effectively inhibit inflammatory responses and maintain Foxp3 stability,which has guiding significance for the application of Tregs in immunotherapy.

关键词： Treg Stability CD147 CD98 CDK2 Immune therapy

Two-Photon Interference with the Type Ⅱ Spontaneous Parametric Down-Conversion

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Chinese Physics Letters 2001年第1期18卷 45-47页

作者： JIANG Yun-Kun SHI Bao-Sen LI Jian DUAN Kai-Min fan Xiao-feng GUO Guang-Can Laboratory of Quantum Communication&Quantum Computation and Department of PhysicsUniversity of Science&Technology of ChinaHefei 230026

The two-photon polarized entangled state is generated from the typeⅡspontaneous parametric down-conversion pumped by a femtosecond *** two-photon interference is observed in the Hong-Ou-Mandel *** high visibility of ... 详细信息

关键词： narrow polarized parametric

K8型单层球面网壳基于AUTODYN的外爆响应分析

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工程力学 2015年第S1期32卷 202-208页

作者：杨帆支旭东范峰结构工程灾变与控制教育部重点实验室(哈尔滨工业大学) 黑龙江哈尔滨150090 哈尔滨工业大学土木工程学院黑龙江哈尔滨150090

该文采用显式动力有限元软件AUTODYN对K8型单层球面网壳在外爆荷载下的动态响应进行了研究。数值模拟中采用流固耦合方法施加荷载,钢材采用多段线性模型,首先验证了AUTODYN进行近场爆炸分析和远场爆炸分析的准确性;考察了跨度为20 m的... 详细信息

该文采用显式动力有限元软件AUTODYN对K8型单层球面网壳在外爆荷载下的动态响应进行了研究。数值模拟中采用流固耦合方法施加荷载,钢材采用多段线性模型,首先验证了AUTODYN进行近场爆炸分析和远场爆炸分析的准确性;考察了跨度为20 m的网壳结构在外爆荷载下的荷载传播规律、最大节点位移变化规律以及塑性杆件发展规律,考察了跨度为40 m网壳结构在TNT质量、炸点距离以及炸点高度参数变化下的结构响应规律。数值分析的结果表明:AUTODYN具备准确进行近场爆炸和远场爆炸分析的能力;单层球面网壳在外爆荷载下主要经历两次冲击波荷载,最大节点位移出现在第一次冲击荷载作用时,结构杆件的塑性发展在0.05 s后基本结束;网壳结构的响应随TNT质量增加和炸点高度增加而加大,随炸点距离增大而减小。

关键词：网壳结构动力响应 AUTODYN 流固耦合外爆

High thermal conductivity and remarkable damping composite gels as thermal interface materials for heat dissipation of chip

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Chip 2022年第2期1卷 27-34页

作者： Sheng-Chang Ding Jian-feng fan Dong-Yi He Lin-feng Cai Xiang-Liang Zeng Lin-Lin Ren Guo-Ping Du Xiao-Liang Zeng Rong Sun Shenzhen Institute of Advanced Electronic Materials Shenzhen Institute of Ad-vanced TechnologyChinese Academy of SciencesShenzhen518055China School of Physics and Materials Science Nanchang UniversityNanchang 330031China

The emerging applications of composite gels as thermal interface ma-terials(TIMs)for chip heat dissipation in intelligent vehicle and wear-able devices require high thermal conductivity and remarkable damp-ing ***,thermal conductivity and damping proper-ties are usually correlated and coupled each ***,inspired by Maxwell theory and adhesion mechanism of gecko’s setae,we present a strategy to fabricate polydimethylsiloxane-based composite gels in-tegrating high thermal conductivity and remarkable damping prop-erties over a broad frequency and temperature *** multiple relaxation modes of dangling chains and the dynamic interaction be-tween the dangling chains and aluminum fillers can efficiently dis-sipate the vibration energy,endowing the composite gels with ultra-high damping property(tanδ>0.3)over a broad frequency(0.01-100 Hz)and temperature range(-50-150°C),which exceeds typi-cal state-of-the-art damping *** dangling chains also com-fort to the interfaces between polymer matrix and aluminum via van der Waals interaction,resulting in high thermal conductivity(4.72±0.04 W m-1 K-1).Using the polydimethylsiloxane-based composite gel as TIMs,we demonstrate effective heat dissipation in chip oper-ating under vigorous *** believe that our strategy could be applied to a wide range of composite gels and lead to the devel-opment of high-performance composite gels as TIMs for chip heat dissipation.

关键词： Thermal interface materials Composite gels Damping Ther-mal conductivity Dangling chains

Increasing both the electromagnetic shielding and thermal conductive properties of three-dimensional graphene-CNT-SiC hybrid materials

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New Carbon Materials 2024年第6期39卷 1178-1190页

作者： fan feng Zhi-dong Han Bing Wei Yang Wang Fei-zhou Wang Yan-yan Jiao Zhen-ting Wang School of Materials Science and Chemical Engineering Harbin University of Science and Technology Harbin 150081 China Qitaihe Baotailong Graphene new materials Co. LTD Qitaihe 154603 China School of Materials Science and Engineering Heilongjiang University of Science and Technology Harbin 150022 China

During the operation of electronic devices, a considerable amount of heat and electromagnetic radiation is emitted. Therefore, the investigation of materials with electromagnetic shielding and thermal management abilities has significant importance. Hybrid materials of three-dimensional graphene networks containing both carbon nanotubes (CNTs) and SiC whiskers (3D graphene-CNT-SiC) were synthesized. Using an aqueous-phase reduction method for the self-assembly of the graphene oxide, a three-dimensional porous graphene structure was fabricated. SiC whiskers, inserted between the graphene layers, formed a framework for longitudinal thermal conduction, while CNTs attached to the SiC surface, created a dendritic structure that increased the bonding between the SiC whiskers and graphene, improving dielectric loss and thermal conductivity. It was found that the thermal conductivity of the hybrid material reached 123 W·m –1 ·K –1 , with a shielding effectiveness of 29.3 dB when the SiC addition was 2%. This result indicates that 3D Graphene-CNT-SiC has excellent thermal conductivity and electromagnetic shielding performance.

关键词： Thermal management Electromagnetic Shielding 3D graphene Silicon carbide Carbon nanotubes

Modular construction mechanics of a European pressurized reactor steel containment liner

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2017年第6期18卷 467-486页

作者： Jia-chuan YAN Xiao-fei JIN feng QIN Zheng LI feng fan Jin-ping OU Key Lab of Structures Dynamic Behavior and Control of the Ministry of Education Harbin Institute of Technology Harbin 150090 China School of Civil Engineering Harbin Institute of Technology Harbin 150090 China China Construction First Engineering Division Corporation Limited Beijing 101300 China Country Garden Foshan 528312 China China Construction Second Engineering Bureau Nuclear Power Plants Branch Shenzhen 518034 China

A European pressurized reactor （EPR） steel containment liner structure is comprised of the cylinder part and the dome part. An introduction of the steel liner structure is presented, followed by studies on the key mechanical features of the construction process using a refined finite element method. The steel liner was divided into several modules and then assembled during construction. Firstly, the equipment structure used to hoist the liner module was optimized, the lifting lug was analyzed using a multi-scale finite element model; the wind speed limit during lifting was also studied. Subsequently, the effect of internal forces during assembly between the liner modules, the lateral pressure of fresh concrete, the non-uniform temperature load, and the wind load on the cylinder module was analyzed. According to the time-varying structural performance during continuous concrete pouring and the hardening construction, an ＂overlapping element and birth-death element＂ technique was adopted to analyze the deformation and stress of the long-span steel dome liner. In addition, the stability-bearing capacities of the dome structure during construction were also studied, which took into consideration the effect of the initial geometrical imperfections and the elasto-plasticity of the material. This study presents a reference in terms of the mechanics of the construction scheme and the safety of such a type of structure.

关键词： Containment Construction mechanics Steel liner Overlapping element Birth-death element

Highly ordered arrangement of meso-tetrakis(4-aminophenyl)porphyrin in self-assembled nanoaggregates via hydrogen bonding

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Chinese Chemical Letters 2014年第5期25卷 752-756页

作者： Qing-Yun Liu Qing-Yan Jia Ji-Qin Zhu Qian Shao Jun-feng fan Dong-Mei Wang Yan-Sheng Yin College of Chemistry and Chemical Engineering Ocean University of China College of Chemical and Environmental Engineering Shandong University of Science and Technology Institute of Marine Materials Science and Engineering Shanghai Maritime University

meso-Tetrakis（4-aminophenyl）porphyrin（TAPP） can self-assemble into nanostructures with different morphologies by a phase-transfer *** morphologies（nanospheres,nanorods and nanothorns）of porphyrin nanoaggregates could be easily tuned just by changing the concentration of porphyrin in a proper solvent at room *** images revealed the formation of highly ordered supramolecular arrays of TAPP,i.e. superlattice of TAPP molecules in nanoaggregates,which agreed well with the size of one molecule of ***–vis absorption spectra showed an obvious red shift of the Soret band of TAPP,indicating the formation of J-aggregates of TAPP in nanoaggregates.

关键词： Porphyrin Self-assembly Nanoaggregates Highly ordered Hydrogen bonding

Platinum-Catalyzed Allylic C-H Alkylation with Malononitriles

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CCS Chemistry 2022年第4期4卷 1366-1375页

作者： Lian-feng fan Pei-Pei Xie Pu-Sheng Wang Xin Hong Liu-Zhu Gong Hefei National Laboratory for Physical Sciences at the Microscale Department of ChemistryUniversity of Science and Technology of ChinaHefei 230026 Department of Chemistry Zhejiang UniversityHangzhou 310027 Center for Excellence in Molecular Synthesis of Chinese Academy of Sciences Hefei 230026

The direct functionalization of allylic C-H bonds is distinguished by enabling rapid assembly of structural complexity from simple *** Pd-catalyzed allylic C-H functionalization has been extensively studied,the discovery of new catalytic systems remains fairly ***,we disclose a Pt-catalyzed allylic C-H alkylation of a wide range of α-alkenes by using phosphoramidites as ligands and malononitriles as alkylating ***,the combination of chiral ureacatalyzed Michael addition and Pt-catalyzed allylic C-H alkylation can serve as an efficient protocol to access chiral tetrahydropyran with high levels of diastereo-and *** studies suggest that the Pt-catalyzed allylic C-H activation proceeds through a concerted proton and two-electron transfer process,which is analogous to transition state geometries of Pd catalysis.

关键词： platinum catalysis phosphoramidite C-H activation allylic alkylation concerted proton and two-electron transfer