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Energetic dynamics of the Inner Magnetosphere in Contact with Fast Solar Wind Currents: Case of the Period 1964-2009

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International Journal of Geosciences 2022年第5期13卷 329-348页

作者： Inza Gnanou Aristide Marie Frédéric Gyébré Karim Guibula Christian Zoundi Frédéric Ouattara É cole Normale Supérieure Koudougou Burkina Faso Laboratoire de Recherche en Energétique et Météorologie de l’Espace (LARemE) Université Norbert ZONGO Koudougou Burkina Faso Laboratoire de Chimie @nalytique de Physique Spatiale et Energétique (LAC@PSE) Université Norbert ZONGO Kou-dougou Burkina Faso Université Norbert ZONGO Koudougou Burkina Faso Université Virtuelle du Burkina Faso Karpala Ouagadougou Burkina Faso

The Earth’s magnetosphere is a magnetic shield that protects Earth from high-energy particles and is subject to a series of internal processes caused by jets of the solar wind (SW) that destabilize it. These disturbances affect health as well as technology and become more extreme when SW is more accelerated. Thus, to better understand the impact of high-speed solar wind (HSSW) invasion on the dynamics of the magnetospheric system, a statistical study of HSSW populations was conducted for even (20 and 22) and odd (21 and 23) solar cycles. The regression analysis using the solar-derived fields from all solar cycles, indicates three states of the inner magnetosphere: 1) the 00:00UT-15:00UT period marked by a magnetic reconnection on the day side of the Earth closest to the Sun with the interplanetary magnetic field (IMF) facing South;2) the 15:00UT-21:00UT period where IMF changes from South to North and remains there until 21:00UT;and 3) the 21:00UT-24:00UT period where there is a reconnection on the night side with stretched field lines. Observations made at different phases of solar activity lead us to suggest that the magnetospheric electric field (EM) and the Bz component of IMF (IMF-Bz) are strongly correlated not only at a particular time scale, but at different time scales. We believe that the daily fluctuations of the electrical and magnetic effects of magnetospheric origin currents play a very important role in the dayside magnetic reconnection rate. Moreover, examination of the cycles with different parities shows important amplitudes of the solar causes for the even cycles compared to the odd solar cycles. Therefore, even solar cycles have a strong influence on our socio-economic system compared to odd cycles.

关键词： Magnetosphere Magnetospheric Electric Field Magnetic Field Solar Wind Solar Cycles

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分子印迹型薄膜体声波谐振毒品检测传感器

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光学精密工程 2013年第9期21卷 2272-2278页

作者：陈剑鸣吕启蒙吴光敏楚合群 John d Mai 昆明理工大学MemS实验室云南昆明650500 香港城市大学机械与生物医学工程学系

针对毒品探测的需求,对高灵敏度、高选择性及可工作于液相环境中的传感器进行了研究,利用分子印迹技术(MIT),结合薄膜体声波谐振器(FBAR)和微流体(micro fluidics)技术构造了新型传感器。首先,阐述了用分子印迹技术制作FBAR吸附层材料... 详细信息

针对毒品探测的需求,对高灵敏度、高选择性及可工作于液相环境中的传感器进行了研究,利用分子印迹技术(MIT),结合薄膜体声波谐振器(FBAR)和微流体(micro fluidics)技术构造了新型传感器。首先,阐述了用分子印迹技术制作FBAR吸附层材料的原理,利用分子印迹技术制备了对特定毒品分子具有专一吸附性的印迹材料,将其作为吸附层涂覆在基于微机电系统(MemS)及微流体技术的FBAR上。根据压电方程和运动学方程推导出了FBAR压电振子的等效电路及电学端口输入阻抗公式,构建了以AlN为压电材料的微流体结构FBAR毒品检测传感器模型。对该结构的FBAR传感器进行了理论研究和公式推导,并在理论模型的基础上进行了仿真实验,得到了单位面积质量响度达0.8 pg/Hz·cm2的FBAR传感器。得到的实验结果远高于石英晶体微天平这一传统的质量敏感型传感器,可实现对溶液中毒品分子的快速检测。

关键词：微机电系统薄膜体声波谐振器分子印迹技术微流体技术毒品检测传感器

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cAMP:A second messenger involved in the mechanism of midgut alkalinization in Lutzomyia longipalpis

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Insect Science 2022年第4期29卷 1059-1070页

作者： denise Barguil Nepomuceno Grasielle Caldas d’Ávila Pessoa Leonardo Barbosa Koerich Marcos Horácio Pereira Mauricio Roberto Viana Sant'Anna Ricardo Nascimento Araújo Nelder Figueiredo Gontijo Laboratório de Fisiologia de Insetos Hematófagos Departamento de Parasitologia/ICBUniversidade Federal de Minas GeraisBelo HorizonteMGBrazil

The sand fly Lutzomyia longipalpis is the main vector of Leishmania infantum in the *** sand flies ingest sugar-rich solutions and blood,which are digested in the *** of nutrients is an essential function performed by digestive enzymes,which require appropriate physiological *** of the main aspects that influence enzymatic activity is the gut pH,which must be tightly *** second messengers are frequently involved in the coordination of tightly regulated physiological events,we investigated if the second messenger cAMP would participate in the process of alkalinization in the abdominal midgut of female *** midguts containing the indicator dye bromothymol-blue,cAMP stimulated the alkalinization of the midgut *** another technique based on the use of fluorescein as a pH indicator,we propose that cAMP is involved in the alkalinization of the midgut by activating HCO3-transport from the enterocyte's cytoplasm to the *** results strongly suggested that the carrier responsible for this process would be a HCO3−/Cl−antiporter located in the enterocytes’apical *** promotes the release of alkalinizing hormones in the hemolymph;however,when the enzyme adenylyl cyclase,responsible for cAMP production,was inhibited,we observed that the hemolymph from blood-fed ***’females did not stimulate midgut *** result indicated that hormone-stimulated alkalinization is mediated by *** the present study,we provide evidences that cAMP has a key role in the control of intestinal pH.

关键词： abdominal midgut alkalinization cAMP HCO_(3)^(-)/Cl^(-)antiport hormone Lulcomyia longipalpis

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Gastro-duodenal disease in Africa: Literature review and clinical data from Accra, Ghana

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World Journal of Gastroenterology 2019年第26期25卷 3344-3358页

作者： Timothy N Archampong Richard H Asmah Cathy J Richards Vicki J Martin Christopher d Bayliss Edília Botao Leonor david Sandra Beleza Carla Carrilho department of Medicine and Therapeutics School of Medicine and DentistryUniversity of GhanaAccra Box 4236Ghana department of Genetics and Genome Biology University of LeicesterLeicester LE1 7RHUnited Kingdom department of Medical Laboratory Sciences School of Biomedical and Allied Health SciencesUniversity of GhanaAccra Box 4236Ghana department of Histopathology Leicester Royal InfirmaryLeicester LE1 5WWUnited Kingdom department of Pathology Maputo Central HospitalMaputo POBox 1164Mozambique department of Pathology Medical Faculty of the University of PortoPorto 4200-465Portugal Institute of Molecular Pathology and Immunology at the University of Porto(Ipatimup) Porto 4200-465Portugal Instituto de Investigacao e Inovacao em Saude(i3S) University of PortoPorto 4200-465Portugal department of Pathology Faculty of MedicineEduardo Mondlane UniversityMaputo POBox 257Mozambique

Gastroduodenal disease(Gdd)was initially thought to be uncommon in *** others,lack of access to optimal health infrastructure and suspicion of conventional medicine resulted in the reported prevalence of Gdd being significantly lower than that in other areas of the *** the increasing availability of flexible upper gastro-intestinal endoscopy,it has now become apparent that Gdd,especially peptic ulcer disease(PUd),is prevalent across the continent of *** risk factors for gastric cancer(GCA)include Helicobater pylori(***),diet,Epstein-Barr virus infection and industrial chemical exposure,while those for PUd are ***,non-steroidal antiinflammatory drug(NSAId)-use,smoking and alcohol *** these,*** is generally accepted to be causally related to the development of atrophic gastritis(AG),intestinal metaplasia(IM),PUd and distal ***,we perform a systematic review of the patterns of Gdd across Africa obtained with endoscopy,and complement the analysis with new data obtained on premalignant gastric his-topathological lesions in Accra,Ghana which was compared with previous data from Maputo,*** there is a general lack of structured cohort studies in Africa,we also considered endoscopy-based hospital or tertiary centre studies of symptomatic *** Africa,there is considerable heterogeneity in the prevalence of PUd with no clear geographical ***,there are differences in PUd within-country despite universally endemic *** *** is not uncommon in *** of the African tertiary-centre studies had higher prevalence of PUd when compared with similar studies in western *** additional intriguing observation is a recent,ongoing decline in PUd in some African countries where *** infection is still *** possible reason for the high,sustained prevalence of PUd may be the significant use of NSAIds in local or over-the-counter *** prevalence

关键词： Gastroduodenal Peptic ulcer Gastric cancer Africa Pre-malignant Atrophy Intestinal metaplasia duodenal ulcer Gastric ulcer

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Commanding the Commander:structure of a key protein machinery in endosomal trafficking

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Signal Transduction and Targeted Therapy 2023年第9期8卷 3877-3879页

作者： Xin Yong Chunzhuang Zhou daniel d.Billadeau da Jia Key Laboratory of Birth defects and Related diseases of Women and Children Department of PaediatricsWest China Second University HospitalState Key Laboratory of BiotherapySichuan UniversityChengdu 610041China division of Oncology Research and Schulze Center for Novel Therapeutics Mayo ClinicRochesterMN 55905USA

In a recent study published in Cell1 and two bioRxiv pre-prints,2,3 three studies investigate the structure of the endosomal Commander complex through a combination of X-ray crystal-lography,cryogenic-electron microscopy(Cryo-em),Alphafold predictions and extensive site-directed mutagenesis(Fig.1a),which sheds lights on the molecular characteristics of this evolutionarily-conserved protein machinery,and enables the mapping of mutations causing X-linked intellectual disability(XILd)and Ritscher-Schinzel syndrome(RSS).When proteins enter the endosomal network,they are either transported to lysosome for degradation,or recycled to the plasma membrane or the trans-Golgi network for *** protein machineries are essential for the process,including Retromer,Commander,and several members of the sorting nexin(SNX)*** genes are highly conserved in metazoa and can be found in almost all tissues and cells.

关键词： Commander Command sorting

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Superchiral near fields detect virus structure

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Light(Science & Applications) 2020年第1期9卷 103-112页

作者： Tarun Kakkar Chantal Keijzer Marion Rodier Tatyana Bukharova Michael Taliansky Andrew J.Love Joel J.Milner Affar S.Karimullah Laurence d.Barron Nikolaj Gadegaard Adrian J.Lapthorn Malcolm Kadodwala School of Chemistry Joseph Black BuildingUniversity of GlasgowGlasgow G128QQUK Institute of Molecular Cell and Systems Biology and School of Life SciencesUniversity of GlasgowG128QQ GlasgowUK James Hutton Inst Cell&Mol SciDundee DD25DAUK Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS Moscow 117997Russia School of Engineering Rankine BuildingUniversity of GlasgowGlasgow G128LTUK

Optical spectroscopy can be used to quickly characterise the structural properties of individual ***,it cannot be applied to biological assemblies because light is generally blind to the spatial distribution of the component *** insensitivity arises from the mismatch in length scales between the assemblies(a few tens of nm)and the wavelength of light required to excite chromophores(≥150 nm).Consequently,with conventional spectroscopy,ordered assemblies,such as the icosahedral capsids of viruses,appear to be indistinguishable isotropic spherical *** limits potential routes to rapid high-throughput portable detection appropriate for point-of-care ***,we demonstrate that chiral electromagnetic(em)near fields,which have both enhanced chiral asymmetry(referred to as superchirality)and subwavelength spatial localisation(∼10 nm),can detect the icosahedral structure of virus ***,they can detect both the presence and relative orientation of a bound virus *** illustrate the potential uses of the exquisite structural sensitivity of subwavelength superchiral fields,we have used them to successfully detect virus particles in the complex milieu of blood serum.

关键词： chiral detect fields

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西秦岭新生代钾霞橄黄长岩的地球化学及其岩浆源区性质

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岩石学报 2008年第2期24卷 238-248页

作者：董昕赵志丹莫宣学喻学惠张宏飞李冰 d. J. dEPAOLO 中国地质大学地质过程与矿产资源国家重点实验室中国地质大学地球科学与资源学院北京100083 中国地质大学地质过程与矿产资源国家重点实验室中国地质大学地球科学学院武汉430074 中国地质科学院地球物理地球化学勘查研究所河北廊坊065000 伯克利加利福尼亚大学美国伯克利CA94720

西秦岭礼县地区新生代钾霞橄黄长岩具有贫SiO_2和Al_2O_3,富CaO、Mgo、TiO_2及K_2O+Na_2O的特征,矿物组合中除橄榄石、辉石外,普遍含有霞石、黄长石、白榴石和磁铁矿等矿物。火山岩的∑REE为97.82×10^(-6)～639.1×10^(-6)。岩石以强... 详细信息

西秦岭礼县地区新生代钾霞橄黄长岩具有贫SiO_2和Al_2O_3,富CaO、Mgo、TiO_2及K_2O+Na_2O的特征,矿物组合中除橄榄石、辉石外,普遍含有霞石、黄长石、白榴石和磁铁矿等矿物。火山岩的∑REE为97.82×10^(-6)～639.1×10^(-6)。岩石以强烈富集大离子亲石元素(LILE,如Rb、Ba、K、Sr)和高场强元素(HFSE,如Nb、Th、Ta、P、Zr、Hf等)为特征具有Pb和Ti的负异常。火山岩具有相对高的^(143)Nd/^(144)Nd比值(0.512007～0.512130,ε^(Nd)=+3.4～+5.8)和相对低的^(87)Sr/^(86)Sr比值(0.703374～0.704726)。^(206)Pb/^(204)Pb、^(207)Pb/^(204)Pb和^(208)Ph/^(204)Ph的比值范围分别为18.088～19.112,15.476～15.626和38.071～39.680。岩石的微量元素和Sr、Nd和Pb同位素特征显示其与洋岛玄武岩(OIB)的地球化学特征相似。源区组成显示了亏损地幔端元dM、HIMU端元和富集地幔端元emII这三种地球化学端元混合的特征。

关键词：钾霞橄黄长岩地球化学岩浆源区新生代西秦岭

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Impact of simulated in vitro gastrointestinal digestion on bioactive compounds,bioactivity and cytotoxicity of melon (Cucumis melo L. inodorus) peel juice powder

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Food Bioscience 2022年第3期47卷 1358-1367页

作者： Ricardo Gómez-García Ana A.Vilas-Boas Manuela Machado débora A.Campos Cristóbal N.Aguilar Ana R.Madureira Manuela Pintado Universidade Católica Portuguesa CBQF-Centro de Biotecnologia e Química Fina – Laboratório AssociadoEscola Superior de BiotecnologiaRua Diogo Botelho 13274169-005PortoPortugal BBG-dIA.Bioprocesses and Bioproducts Group.Food Research department School of ChemistryAutonomous University of CoahuilaSaltilloCoahuilaMexico

The objectives of this research work were to evaluate the effect of in vitro gastrointestinal digestion (GIT) on melon peel juice (MPJ) powder from fruit processing industry by-products,considering (i) the recovery and accessibility indexes,(ii) the changes on antioxidant activity,and (iii) the prebiotic *** exposition to GIT conditions a decrease on the total phenolic content (TPC = 65.31%) and antioxidant activity by ABTS = 39.77% and dPPH = 45.91% were ***,these both parameters exhibited stable accessibility,accounting with 81.89%,76.55%,and 54.07% for TPC,ABTS and dPPH,*** gastrointestinal digestion,the non-absorbed fraction exhibited a positive impact on the growth of Bifidobacterium and Lactobacillus strains,possibly associated with the high content of simple sugar (glucose and fructose).This fraction also showed to be safe on Caco-2 intestinal *** findings suggest that MPJ might be used as a potential food functional ingredient.

关键词： Melon by-products Functional ingredients Phenolic antioxidants Simulated digestion Prebiotic effect

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MetaCreations Canoma——从图像到3d对象

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电子与电脑 1999年第11期 41-41页

作者： david em 唐宏

过去,对小项目来说从头开始开发逼真的3d图像不仅价格昂贵而且工作繁琐。现在不再是这样了。利用MetaCreations公司的专用3d建模程序Canoma,你可以方便地把汽车和建筑物的照片转换为3d计算机模型。

关键词：图像对象 MetaCreations Canoma 线框

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Electromagnetic Lifshitz Formula for Small-Width Mirrors from Functional determinants

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Applied Mathematics 2013年第8期4卷 1173-1179页

作者： César d. Fosco María L. Remaggi Instituto Balseiro Universidad Nacional de Cuyo Centro Atómico Bariloche Comisión Nacional de Energ a Atómica Bariloche Argentina

We extend a recently proposed Quantum Field Theory (QFT) approach to the Lifshitz formula, originally implemented for a real scalar field, to the case of a fluctuating vacuum Electromagnetic (em) field, coupled to two flat, parallel mirrors. The general result is presented in terms of the invariants of the vacuum polarization tensors due to the media on each mirror. We consider mirrors that have small widths, with the zero-width limit as a particular case. We apply the latter to models involving graphene sheets, obtaining results which are consistent with previous ones.

关键词： Gelfand-Yaglom Casimir Vacuum

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