Impact of simulated in vitro gastrointestinal digestion on bioactive compounds,bioactivity and cytotoxicity of melon (Cucumis melo L. inodorus) peel juice powder

作     者：Ricardo Gómez-García Ana A.Vilas-Boas Manuela Machado Débora A.Campos Cristóbal N.Aguilar Ana R.Madureira Manuela Pintado 

作者机构：Universidade Católica PortuguesaCBQF-Centro de Biotecnologia e Química Fina – Laboratório AssociadoEscola Superior de BiotecnologiaRua Diogo Botelho 13274169-005PortoPortugal BBG-DIA.Bioprocesses and Bioproducts Group.Food Research DepartmentSchool of ChemistryAutonomous University of CoahuilaSaltilloCoahuilaMexico 

出 版 物：《Food Bioscience》 (食品生物科学（英文）)

年 卷 期：2022年第47卷第3期

页      面：1358-1367页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：National Council of Science and Technology(CONACyT,Mexico)for PhD fellowship support granted to G´omez-García Ricardo the project MultiBiorefinery:Estrat´egias multiuso para a valorizaç˜ao de uma gama alargada de subprodutos agroflorestais e das pescas:Um passo em frente na criaç˜ao de uma biorrefinaria"financiado pelo Programa Operacional Competitividade e Internacionalizaç˜ao(POCI-01-0145-FEDER-016403)e pelo Programa Operacional Regional de Lisboa(LISBOA-01-0145-FEDER-016403) na sua componente FEDER e pela Fundaç˜ao para a Ciˆencia e Tecnologia,I.P.na componente nacional(SAICTPAC/0040/2015) 

主　　题：Melon by-products Functional ingredients Phenolic antioxidants Simulated digestion Prebiotic effect 

摘      要：The objectives of this research work were to evaluate the effect of in vitro gastrointestinal digestion (GIT) on melon peel juice (MPJ) powder from fruit processing industry by-products,considering (i) the recovery and accessibility indexes,(ii) the changes on antioxidant activity,and (iii) the prebiotic *** exposition to GIT conditions a decrease on the total phenolic content (TPC = 65.31%) and antioxidant activity by ABTS = 39.77% and DPPH = 45.91% were ***,these both parameters exhibited stable accessibility,accounting with 81.89%,76.55%,and 54.07% for TPC,ABTS and DPPH,*** gastrointestinal digestion,the non-absorbed fraction exhibited a positive impact on the growth of Bifidobacterium and Lactobacillus strains,possibly associated with the high content of simple sugar (glucose and fructose).This fraction also showed to be safe on Caco-2 intestinal *** findings suggest that MPJ might be used as a potential food functional ingredient.