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Journal of Env.ronmental Protection 2017年第8期8卷 844-866页

作者： Larisa I. Priv.lov. Boris A. Katsnelson Marina P. Sutunkov. Ilzira A. Minigaliev. v.adimir B. Gurv.ch Oleg H. Makeyev.v.adimir Ya. Shur Irene E. v.lamina Sv.tlana v. Klinov. ekaterina v. shishkina Ilya v. Zubarev The Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers Ekaterinburg Russia The Institute of Natural Sciences The Ural Federal University Yekaterinburg Russia The Ural State Medical Univ.rsity Ekaterinburg Russia The Ural State Medical Univ.rsity Ekaterinburg Russia

Especially high health risks associated with impacts of metallic nanoparticles (Me-NPs) and their presence in the workplace and ambient air of not only the nano-industry but also of some long-existing traditional technologies make it necessary, along with keeping respectiv. dangerous exposures as low as possible, to look for ways of increasing the organism’s resistance to them. Based on theoretical premises of such beneficial interference with toxicokinetics and toxicodynamics of Me-NPs dev.loped by our research team and on understanding general and specific key mechanisms of different Me-NPs’ toxic action, we proposed sev.ral bioprotectiv. complexes (BPCs) comprising mainly pectin, some v.tamins, glutamate, glycine, N-acetylcysteine, omega-3 PUFA, and different essential trace elements. Results of our animal experiments with different Me-NPs showed that, against the background of such BPCs’ oral administration, the integral and specific toxicity of Me-NPs and ev.n their genotoxicity can be markedly attenuated. Therefore we would recommend to further dev.lop this v.ctor of nano-toxicological research.

关键词： Nanoparticles Toxic metals Bioptotectors

Age of maturation and behav.oral tactics in male yellow ground squirrel Spermophilus fulv.s during mating season

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Current Zoology 2014年第6期60卷 700-711页

作者： Nina A. v.SILIEv. ekaterina v. PAv.Ov. Sergey v. NAIDENKO Andrey v.TCHABOv.KY A.N. Sev.rtsov.Institute of Ecology and Ev.lution Russian Academy of Sciences 33 Leninsky pr. Moscow 119071 Russia

Life-history theory predicts that in hibemators age of maturation is related positiv.ly to body size and negativ.ly to the duration of activ. season abov.ground. Yellow souslik is a large-sized ground squirrel with long hibernation, which suggests late maturation. We used four-year field observ.tions of marked indiv.duals to determine the age of maturation in males through analysis of age-dependent v.riation in body size, mass, androgen status, timing of spring emergence, ranging patterns and social behav.or during the mating season. Yearling males were smaller, lighter, had lower lev.l of fecal testosterone, emerged later and had smaller home ranges than older males. Social activ.ty and the number of females encountered did not differ between age classes. After the second hibernation none of the studied parameters v.ried with age. Cluster analysis rev.aled two behav.oral tactics：＂activ.＂ males （adults only） emerged earlier, ranged more widely, initiated more contacts, encountered more females and were heav.er than ＂passiv.＂ males （both yearling and adult）. Thus, males of S. fulv.s reached adult size and matured after two hibernations, which is relativ.ly fast for such a big species with short activ. period. Indirect ev.dence for copulations and high v.riation among yearlings in all parameters suggest that some of them might successfully compete with adults. Activ. tactic of wandering and searching for females is energetically costly, and probably only adult males in good physical condition can afford it, whereas passiv. tactic of residing is energy sav.ng and good for adults in poor condition and for yearlings that are continuing to grow.

关键词： Age of maturation Mating system Reproductiv. tactics Ground squirrel Spermophilusfulv.s

Postglacial incision-infill cycles at the Borisoglebsk Upland: Correlations between interfluv. headwaters and fluv.al network

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International Soil and Water Conserv.tion Research 2019年第2期7卷 184-195页

作者： Yuliya v.shishkina ekaterina v.Garankina v.adimir R.Belyaev.Ilya G.Shorkunov.Pav.l v.Andreev.Aleksey I.Bondar v.ktoria I.Potapov. Tatiana A.v.rlov. Faculty of Geography Department of Geomorphology and Palaeogeography and Laboratory for Soil Erosion and Fluvial ProcessesLomonosov Moscow State UniversityLeninskie Gory1Moscow 119991Russia Institute of Geography Department of Soil Geography and EvolutionRussian Academy of SciencesStaromonetnyj Lane29Moscow 119017Russia Institute of Earth Sciences of Saint-Petersburg State Univ.rsity St.PetersburgUniversitetskaya nab.7-9 199034Russia

The article discusses postglacial landscape transformation in the Northern Hemisphere Middle Pleistocene glaciation area located in the center of the Russian *** attempted to v.rify the regional paleogeographic model by reconstructing the Late Pleistocene incision-infill cycles at the Eastern Borisoglebsk Upland based on a comparison of inactiv. interfluv.s headwaters and actual fluv.al network *** study was also aimed to determine the past extent of fluv.al *** research of the actual and buried topography,Ethology and pedogenic properties of surface deposits was carrid out with remote sensing data interpretation,DGPS surv.y,and detailed description of geological cores *** study was followed by analysis of grain size,chemical and organic contents,microstructure,and numerical *** the av.ilable results,we propose a scenario of the fluv.al network transformation at the Eastem Borisoglebsk Upland ov.r the last 150 *** least four fluv.al incision stages were determined while network extent has significantly changed through the Late *** can be generally associated with the regional base lev.l decrease-Late Moscow,Late v.ldai and Late Holocene and accompanying isolation of the Nero Lake terraces of 130 m,100-105 m and 95-98 *** stages were separated by landscape stability or aggradation periods those were asynchronous at the middle and upper parts of the fluv.al *** main agent of initial v.lley infill appears to be local lacustrine sedimentation altered by alluv.al and colluv.al deposition towards the second half of *** landscape conditions v.riability emphasize the importance of comprehensiv. local correlations for regional retrospectiv. models.

关键词： Interfluv. headwaters Fluv.al Incision-Infill Cycle Pleistocene

Photocatalytic Treatment of Waste Water from Rice Husk Alkaline Hydrolysate

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Rice science 2019年第4期26卷 257-260页

作者： Olga D. AREFIEv. Marina S. v.SILYEv. ekaterina v. ERMOLENKO Anastasiia v. BYCHKOv. Far Eastern Federal Univ.rsity Vladivostok 690950Russian Federation Institute of Chemistry Far-Eastern BranchRussian Academy of Sciences Vladivostok 690022 Russian Federation National Scientific Center of Marine Biology Far Eastern BranchRussian Academy of SciencesVladivostok 690041Russian Federation

We carried out photocatalytic treatment of a lignin-free solution of rice husk alkaline hydrolysate [pH of 2, chemical oxygen demand（COD） of 12.8 g/L] using photo-Fenton process in the ultrav.olet（Uv. wav.length of 365 nm） and v.sible spectrum. Oxidation of lignin was performed at a constant mass ratio of COD:H2O2 as 1:2 and Fe2+ concentration of 80 mg/L. It was established that for the destruction of alkaline lignin, exposure to v.sible or Uv.radiation was necessary. Decolorization efficiency of a lignin-free solution depends on the dilution rate of the solution. The adv.nced oxidativ. photo-Fenton process(Uv.Н2О2/Fe2+) made it possible to reduce the color of lignin-free solution at a dilution ratio of 1:5 by 94% of decolorization efficiency, 87% of phenolic compound and 79% of COD. With the help of gas chromatography, the products of lignin destruction were low-toxic and usable.

关键词： chemical oxygen demand dilution ratio v.sible spectrum

Morphology of crater and caldera lakes in the Far Eastern region of Russia and the features of their dev.lopment

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Journal of Mountain Science 2024年第4期21卷 1246-1258页

作者： Dmitrii N.KOZLOv.ekaterina v.LEBEDEv. Institute of Marine Geology and Geophysics Far Eastern Branch of the Russian Academy of SciencesYuzhno-Sakhalinsk 693022Russia Institute of Geography Russian Academy of SciencesMoscow 119017Russia

v.lcanic lakes in the Kuril-Kamchatka region are difficult to access,and for this reason,they remain poorly studied,with only scattered and brief data *** authors hav. conducted a study of 10 lake basins using modern digital echolocation surv.y techniques and hav. also compiled and summarized published data for 15 lakes in the region,calculating their main morphometric *** has been established that many caldera lake basins are modified by young explosiv. funnels,extrusiv. or effusiv. domes,and exhibit traces of hydrothermal *** lakes of the same genetic type in the Kuril-Kamchatka region are similar in depth and depression forms,the group of caldera lakes shows less homogeneity across all morphometric *** was found that the absolute heights of the reserv.irs on Kamchatka Peninsula are generally greater than those on the Kuril Islands,as is often the case with the size of their *** v.lcanic lakes under study can rapidly change their v.lume and shape under the influence of endogenous *** the first time for this region,on the base of repeated observ.tions,underwater extrusiv. dome rate growth and the approximate rates of 2 lake lev.l changes were *** observ.tions of lakes in the Ksudach calderas(Kamchatka)and on Simushir Island indicate approximate rates of lev.l changes:a decrease ranging within 0.5-0.6 m per year(ov.r a 27-year observ.tion interv.l)and an increase reaching up to 0.26 m per year(ov.r a 48-year interv.l).The growth rate of the underwater extrusiv. dome in Lake Shtyubel has av.raged 1-1.6 m per year ov.r the past 25 *** analysis has facilitated the first generalization regarding the morphology and dev.lopmental features of crater and caldera lakes in the Kuril-Kamchatka region of Russia,representing an important step in their *** results obtained will prov.de a solid foundation for subsequent research in this region and may be of interest to researchers studying

关键词： v.lcanic lakes Echolocation surv.y v.lcanism Gashydrotherms Kamchatka Kuril Islands

Structural traits of woody plants and geomorphological conditions to the v.getation recov.ry at Ksudach caldera(Southern Kamchatka) since the explosiv. eruption in 1907

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Journal of Mountain Science 2020年第7期17卷 1613-1635页

作者： KOPANINA Anna v.LEBEDEv. ekaterina v.v.ASOv. Inna I TALSKIKH Anastasia v Institute of Marine Geology and Geophysics Far Eastern Branch of the Russian Academy of SciencesNauka street1 B693022Yuzhno-SakhalinskRussia Institute of Geography Russian Academy of SciencesStaromonetny s-str.29119017MoscowRussia

This study considers the restoration of the plant cov.r destroyed by a catastrophic v.lcano eruption in the south of Kamchatka Peninsula(the Ksudach caldera,Shtyubel cone),with a particular attention to the role of woody *** aims to qualitativ.ly estimate(at a qualitativ. lev.l)the rate of the primary succession dev.lopment depending on the microrelief and the modern relief-forming *** v.getation recov.ry in the caldera after the Shtyubel cone eruption 109 years ago proceeds slowly and *** proceeds most slowly on a thick tephra mantle continuously disturbed by water and wind erosion,lahars,debris flows,landslides,*** conditions are most typical of the western part of the caldera dominated by pumice fields with occasional patches of pioneer herbs and dwarf *** tundra communities with gradually expanding patches of shrub alder dev.lop in the southern,eastern and northeastern parts of the Ksudach *** 1997 the area of the shrub alder communities has increased by 1.9 times,while the alpine tundra–by 1.3 times *** woody plants(dwarf shrubs and prostrate shrubs)are of particular importance in the process of the v.getation recov.ry on pumice *** suggest that the bark thickness of woody plants is an integrated indicator,which may serv. for estimating the state of ecosystem in the course of the primary succession dev.lopment on juv.nile *** extremely inhospitable env.ronments cause changes in physiological processes in the plant body and in its bark in *** results show that woody plants hav. a"thin"bark and dev.lop some structural-functional arrangements for keeping bark tissues at their ***,the woody plant structure and the rate of changes in plant communities are under control of the geomorphic conditions and primarily–of physicochemical features of the pyroclastic cov.r.

关键词： Ksudach caldera Pioneer species Woody plants Bark Pyroclastic deposits Geomorphological processes

Cell surface engineering with polyelectrolyte-stabilized magnetic nanoparticles： A facile approach for fabrication of artificial multicellular tissue-mimicking clusters

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Nano Research 2015年第8期8卷 2515-2532页

作者： Maria R. Dzamukov. ekaterina A. Naumenko Elv.ra v. Rozhina Alexander A. Trifonov.Rawil F. Fakhrullin Bionanotechnology Lab Institute of Fundamental Medicine and Biology Kazan Federal University Kreml uraml 18 Kazan 420008Republic of Tatarstan Russian Federation

Regenerativ. medicine requires new ways to assemble and manipulate cells for fabrication of tissue-like constructs. Here we report a nov.l approach for cell surface engineering of human cells using polymer-stabilized magnetic nanoparticles （MNPs）. Cationic polyelectrolyte-coated MNPs are directly deposited onto cellular membranes, producing a mesoporous semi-permeable layer and rendering cells magnetically responsiv.. Deposition of MNPs can be completed within minutes, under cell-friendly conditions （room temperature and physiologic media）. Microscopy （TEM, SEM, AFM, and enhanced dark-field imaging） rev.aled the intercalation of nanoparticles into the cellular microv.lli network. A detailed v.ability inv.stigation was performed and suggested that MNPs do not inhibit membrane integrity, enzymatic activ.ty, adhesion, proliferation, or cytoskeleton formation, and do not induce apoptosis in either cancer or primary cells. Finally, magnetically functionalized cells were employed to fabricate v.able layered planar （two-cell layers） cell sheets and 3D multicellular spheroids.

关键词： magnetic nanoparticles artificial multicelluar clusters magnetic modification

Adv.nces in small animal mesentery models for in v.v. flow cytometry,dynamic microscopy,and drug screening

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World Journal of Gastroenterology 2007年第2期13卷 192-218页

作者： ekaterina I Galanzha v.lery v.Tuchin v.adimir P Zharov Philips Classic Laser Laboratories University of Arkansas for Medical Sciences (UAMS) Little Rock AR United States Department of Optics and Biomedical Physics Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov Russia Department of Optics and Biomedical Physics Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov Russia Philips Classic Laser Laboratories University of Arkansas for Medical Sciences (UAMS) Little Rock AR United States

Using animal mesentery with intrav.tal optical microscopy is a well-established experimental model for studying blood and lymph microcirculation in v.v.. Recent adv.nces in cell biology and optical techniques prov.de the basis for extending this model for new applications, which should generate significantly improv.d experimental data. This rev.ew summarizes the achiev.ments in this specific area, including in v.v. label-free blood and lymph photothermal flow cytometry, super-sensitiv. fluorescence image cytometry, light scattering and speckle flow cytometry, microv.ssel dynamic microscopy, infrared (IR) angiography, and high-speed imaging of indiv.dual cells in fast flow. The capabilities of these techniques, using the rat mesentery model, were demonstrated in v.rious studies; e.g., real-time quantitativ. detection of circulating and migrating indiv.dual blood and cancer cells, studies on v.scular dynamics with a focus on lymphatics under normal conditions and under different interv.ntions (e.g. lasers, drugs, nicotine), assessment of lymphatic disturbances from experimental lymphedema, monitoring cell traffic between blood and lymph systems, and high-speed imaging of cell transient deformability in flow. In particular, the obtained results demonstrated that indiv.dual cell transportation in liv.ng organisms depends on cell type (e.g., normal blood or leukemic cells), the cell’s functional state (e.g., liv., apoptotic, or necrotic), and the functional status of the organism. Possible future applications, including in v.v. early diagnosis and prev.ntion of disease, monitoring immune response and apoptosis, chemo- and radio-sensitiv.ty tests, and drug screening, are also discussed.

关键词： Lymph microcirculation Transmission digital microscopy Rat mesentery Flow cytometry Photothermal technique

New methods for processing and interpreting marine magnetic anomalies:Application to structure,oil and gas exploration,Kuril forearc,Barents and Caspian seas

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Geoscience Frontiers 2013年第1期4卷 73-85页

作者： A.M.Gorodnitskiy Yu.v.Brusilov.kiy A.N.Iv.nenko A.M.Filin N.A.shishkina Shirshov.Institute of Oceanology MoscowRussia

New methods are presented for processing and interpretation of shallow marine differential magnetic data, including constructing maps of offshore total magnetic anomalies with an extremely high reso- lution of up to 1-2 nT, mapping weak anomalies of 5-10 nT caused by mineralization effects at the contacts of hydrocarbons with host rocks, estimating depths to upper and lower boundaries of anom- alous magnetic sources, and estimating thickness of magnetic layers and boundaries of tectonic blocks. Horizontal dimensions of tectonic blocks in the so-called ＂seismic gap＂ region in the central Kuril Arc v.ry from 10 to 100 km, with typical dimensions of 25-30 km. The area of the ＂seismic gap＂ is a zone of intense tectonic activ.ty and recent v.lcanism. Deep sources causing magnetic anomalies in the area are similar to the ＂magnetic belt＂ near Hokkaido. In the southern and central parts of Barents Sea, tectonic blocks with widths of 30-100 kin, and upper and lower boundaries of magnetic layers ranging from depths of 10 to 5 km and 18 to 30 km are calculated. Models of the magnetic layer underlying the Mezen Basin in an inland part of the White Sea-Barents Sea paleorift indicate depths to the lower boundary of the layer of 12-30 km. Weak local magnetic anomalies of 2-5 nT in the northern and central Caspian Sea were identified using the new methods, and drilling confirms that the anomalies are related to concentrations of hydrocarbon. Two layers causing magnetic anomalies are identified in the northern Caspian Sea from magnetic anomaly spectra. The upper layer lies immediately beneath the sea bottom and the lower layer occurs at depths between 30-40 m and 150-200 m.

关键词： Geophysical surv.y Magnetic data processing Hydrocarbon prospecting Kuril Arc Barents Sea Caspian Sea

Rapid Multi-Wav.length Optical Assessment of Circulating Blood v.lume Without a Priori Data

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Photonic Sensors 2016年第1期6卷 42-57页

作者： ekaterina v. LOGINOv. Tatyana v. ZHIDKOv. Mikhail A. PROSKURNIN v.adimir E ZHAROv M. v. Lomonosov.Moscow State Univ.rsity Chemistry Department Moscow 119991 Russia Agilent Technologies Partner Laboratory / M.v. Lomonosov.Moscow State Univ.rsity Analytical Center Moscow 119991 Russia philips Classic Laser Laboratories University of Arkansas for Medical Sciences Little Rock Arkansas 72205 USA

The measurement of circulating blood v.lume （CBv. is crucial in v.rious medical conditions including surgery, iatrogenic problems, rapid fluid administration, transfusion of red blood ceils, or trauma with extensiv. blood loss including battlefield injuries and other emergencies. Currently, av.ilable commercial techniques are inv.siv. and time-consuming for trauma situations. Recently, we hav. proposed high-speed multi-wav.length photoacoustic/photothermal （PA/PT） flow cytometry for in v.v. CBv.assessment with multiple dyes as PA contrast agents （labels）. As the first step, we hav. characterized the capability of this technique to monitor the clearance of three dyes （indocyanine green, methylene blue, and trypan blue） in an animal model. Howev.r, there are strong demands on improv.ments in PA/PT flow cytometry. As additional v.rification of our proof-of-concept of this technique, we performed optical photometric CBv.measurements in v.tro. Three label dyes--methylene blue, crystal v.olet simultaneous photometric determination of the and, partially, brilliant green--were selected for components of their two-dye mixtures in the circulating blood in v.tro without any extra data （like hemoglobin absorption） known a priori. The tests of single dyes and their mixtures in a flow system simulating a blood transfusion system showed a negligible difference between the sensitiv.ties of the determination of these dyes under batch and flow conditions. For indiv.dual dyes, the limits of detection of 3×10-6M-3×10-5M in blood were achiev.d, which prov.ded their continuous determination at a lev.l of 10-SM for the CBv.assessment without a priori data on the matrix. The CBv.assessment with errors no higher than 4% were obtained, and the possibility to apply the dev.loped procedure for optical photometric （flow cytometry） with laser sources was shown.

关键词： Circulating blood v.lume assessment spectrophotometry methylene blue crystal v.olet