检索结果-南通市图书馆

Unveiling Cellular Internalization Dynamics of Single Gold Nanorods by Tracking Their Orientational and Translational Motions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CCS Chemistry 2022年第4期4卷 1295-1304页

作者： Dong Xu Yi Du Feng Ge Yan He edward S.Yeung National Engineering Laboratory for Rice and By-Products Further Processing College of Food Science and EngineeringCentral South University of Forestry&TechnologyChangsha 410004 State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringCollege of BiologyHunan UniversityChangsha 410082 Department of Chemistry Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology(Ministry of Education)Tsinghua UniversityBeijing 100084 Department of Chemistry Iowa State UniversityAmesIA 50011

Single nanoparticle tracking(SPT)is a unique and powerful tool to investigate the interaction between nanoparticles and cells,which is of considerable importance for nanotechnology applications in biomedical fields and in-depth understanding of biological ***,previous work typically focused on translations of single nanoparticles while they undergo both translational and rotational *** this study,we obtained both the translational and rotational dynamics of single gold nanorods during their cellular internalization process using dual-channel polarization *** particular,the azimuth and polar angles were integrated into a polar coordinate systemto obtain three general orientation distribution patterns,found to have a close relationship with the nanoparticle cellular internalization process and time-dependent ***,the patterns accompanied by trajectories,translational and rotational coefficients,the azimuth and polar angles,and other parameters provided a wealth of knowledge on the nanoparticle cellular internalization dynamics with unprecedented *** observed that the gold nanorods could initially assume a tip-first quick rotation state with partially restricted orientations,then change to a strongly confined near-vertical insertion state with slight angular fluctuations,and eventually transform into a random and fast rotation *** methodology opens up a new avenue for a detailed understanding of biological processes.

关键词： orientation distribution pattern nanoparticle cellular internalization orientational and translational motion single nanoparticle tracking

Petrological implication of wagnerite-Ma5bc in the quartzofeldspathic gneiss, Larsemann Hills, East Antarctica

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Progress in Natural Science:Materials International 2005年第6期15卷 523-529页

作者： edward S. GREW 5790 edward T. Bryand Research Center Department of Earth Sciences Maine 04469-5790 Orono USA University of Maine

Wagnerite-Ma5bc polytype is found in a gneiss associated with cordierite-prismatine-bearing gneiss, northern Stornes Peninsula, Larsemann Hills, East Antarctica. Wagnerite coexists with apatite and both of them are present as rock-forming minerals. Ca depletion is not essential to the formation of wagnerite; sufficient Mg, P and F components, and a relatively low Ca/Mg ratio is critical, otherwise only apatite crystallizes. Strong anatexis of the quartzofeldspathic gneiss of the area results in differentiation and separate enrichment of leuco- and melanocratic components. P and F tend to accumulate in the mafic-rich melanocratic component, and when their abundance reaches certain concentration, wagnerite forms. It is perhaps the chemistry of the setting that controls the appearance of wagnerite, whereas the PT condition is responsible for the variety of wagnerite polytype. A disordered polytype crystallizes at relatively high temperature, then cools down slowly and transforms into one of the ordered polytypes, in this case, the Ma5bc polytype.

关键词： wagnerite-Ma5bc polytype anatexis formation condition volatile components Larsemann Hills.

Interpretable discovery of semiconductors with machine learning

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

npj Computational Materials 2023年第1期9卷 1150-1160页

作者： Hitarth Choubisa Petar Todorović Joao M.Pina Darshan H.Parmar Ziliang Li Oleksandr Voznyy Isaac Tamblyn edward H.Sargent Department of Electrical and Computer Engineering University of Toronto10 King’s College RoadTorontoON M5S 3G4Canada Department of Physical and Environmental Sciences University of TorontoScarboroughON M1C 1A4Canada Department of Physics University of OttawaOttawaON K1N 6N5Canada Vector Institute for Artificial Intelligence TorontoON M5G 1M1Canada

Machine learning models of material properties accelerate materials discovery,reproducing density functional theory calculated results at a fraction of the cost1–*** bridge the gap between theory and experiments,machine learning predictions need to be distilled in the form of interpretable chemical rules that can be used by *** we develop a framework to address this gap by combining evolutionary algorithm-powered search with machine-learning surrogate *** then couple the search results with supervised learning and statistical *** strategy enables the efficient search of a materials space while providing interpretable design *** demonstrate its effectiveness by developing rules for the design of direct bandgap materials,stable UV emitters,and IR perovskite ***,we conclusively show how DARWIN-generated rules are statistically more robust and applicable to a wide range of applications including the design of UV halide perovskites.

关键词： preta learning perovskite

Advances in shape measurement in the digital world

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2016年第3期14卷 19-31页

作者： Xiaodong Jia edward J. Garboczi School of Chemical and Process Engineering University of Leeds Leeds IS2 9JT. UK Material Measurement Laboratory National Institute of Standards and Technology Boulder CO 80305. USA

The importance of particle shape in terms of its effects on the behaviour of powders and other particulate systems has long been recognised, but particle shape information has been rather difficult to obtain and use until fairly recently, unlike its better-known counterpart, particle size. However, advances in computing power and 3D image acquisition and analysis techniques have resulted in major progress being made in the measurement, description and application of particle shape information in recent years. Because we are now in a digital era, it is fitting that many of these advanced techniques are based on digital technology. This review article aims to trace the development of these new techniques, highlight their contributions to both academic and practical applications, and present a perspective for future developments.

关键词： Particle shape Digital methods Shape measurement Spherical harmonics X-ray tomography

Vascular resection and reconstruction at pancreatico-duodenectomy:technical issues

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2012年第3期11卷 234-242页

作者： edward CS Lai Pedder Clinic 4/F 9 Queen's Road Central

BACKGROUND:With the improvement of perioperative management over the years,pancreatico-duodenectomy has become a safe operation despite its technical *** presence of concomitant visceral artery occlusion unrelated to the underlying malignancy and concomitant major venous infiltration by tumor poses additional hazards to resection which could compromise the postoperative *** SOURCES:A MEDLINE database search was performed to identify relevant articles using the key ords 'median arcuate ligament syndrome','superior mesenteric artery','replaced right hepatic artery',and 'portal vein resection'.Additional papers and book chapters were identified by a manual search of the references from the key ***:Computed tomography with 3-dimensional reconstruction of the vascular anatomy provides most key information on the potential vascular problems encountered during surgery.A trial clamping of the gastroduodenal artery provides a simple intraoperative assessment for the presence of any significant visceral arterial *** on the timing of diagnosis,division of the median arcuate ligament,bypass or endovascular stenting should be *** and superior mesenteric vein resection had been used with increasing frequency and *** steps and methods taken to reconstruct the venous continuity vary with individual surgeons,and the anatomical variations *** segmental loss of the portal vein,opinions differs with regard to the preservation of the splenic vein,and when divided,the necessity of restoring its continuity;source of the autologous vein graft when needed and whether the use of synthetic graft is a safe ***:During a pancreatico-duodenectomy,images of computed tomography must be carefully studied to appreciate the changes and variation of vascular *** preoperative preparation,acute awareness of the probable arterial and venous anatomical variation and the availability of expert

关键词： pancreatico-duodenectomy vein resection celiac axis compression

Hydrogels for the management of second-degree burns:currently available options and future promise

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Burns & Trauma 2022年第1期10卷 71-87页

作者： Katherine A.Cook Edith Martinez-Lozano Robert Sheridan edward K.Rodriguez Ara Nazarian Mark W.Grinstaff Department of Chemistry Biomedical Engineeringand MedicineBoston UniversityBostonMA02215USA Musculoskeletal Translational Innovation Initiative Carl J.ShapiroDepartment of Orthopaedic SurgeryBeth Israel Deaconess Medical Center and Harvard Medical SchoolBostonMA02215USA Shriners Hospitals for Children and Burns Service Department of SurgeryMassachusetts General HospitalBostonMA02214USA Department of Orthopaedic Surgery Yerevan State Medical UniversityYerevanArmenia

Burn wounds result from exposure to hot liquids,chemicals,fire,electric discharge or *** severity ranges from first-degree injury,which is superficial,to fourth-degree injury,which exposes bone,tendons and *** assessment of burn depth and accurate wound management in the outpatient setting is critical to prevent injury progression into deeper layers of the *** progression is of particular pertinence to second-degree burns,which are the most common form of thermal *** our understanding of wound healing advances,treatment options and technologies for second-degree burn management also *** hydrogels are a class of burn wound dressings that adhere to tissue,absorb wound exudate,protect from the environment,can be transparent facilitating serial wound evaluation and,in some cases,enable facile removal for dressing *** review briefly describes the burn level classification and common,commercially available dressings used to treat second-degree burns,and then focuses on new polymeric hydrogel burn dressings under preclinical development analyzing their design,structure and *** review presents the follow key learning points:(1)introduction to the integument system and the wound-healing process;(2)classification of burns according to severity and clinical appearance;(3)available dressings currently used for second-degree burns;(4)introduction to hydrogels and their preparation and characterization techniques;and(5)pre-clinical hydrogel burn wound dressings currently being developed.

关键词： Burn Wound Hydrogel Dressing Second-degree

The roles of bone remodeling in normal hematopoiesis and age-related hematological malignancies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bone Research 2023年第2期11卷 273-291页

作者： Hengwei Zhang Jane LLiesveld Laura MCalvi Brea CLipe Lianping Xing Michael WBecker edward MSchwarz Shu-Chi A.Yeh Center for Musculoskeletal Research University of Rochester Medical Center601 Elmwood AveBox 665RochesterNY14642USA Department of Pathology and Laboratory Medicine University of Rochester Medical CenterRochesterNYUSA Wilmot Cancer Center University of Rochester Medical CenterRochesterNYUSA Department of Medicine Division of Hematology/Oncology and Bone Marrow Transplantation ProgramUniversity of Rochester Medical CenterRochesterNYUSA Department of Medicine Division of Endocrinology/MetabolismUniversity of Rochester Medical CenterRochesterNYUSA Department of Orthopaedics University of Rochester Medical CenterRochesterNYUSA Department of Medicine Division of Allergy/Immunology/RheumatologyUniversity of Rochester Medical CenterRochesterNYUSA Department of Biomedical Engineering University of RochesterNYUSA Department of Physiology/Pharmacology University of Rochester Medical CenterRochesterNYUSA

Prior research establishing that bone interacts in coordination with the bone marrow microenvironment(BMME)to regulate hematopoietic homeostasis was largely based on analyses of individual bone-associated cell *** advances in intravital imaging has suggested that the expansion of hematopoietic stem cells(HSCs)and acute myeloid leukemia cells is restricted to bone marrow microdomains during a distinct stage of bone *** findings indicate that dynamic bone remodeling likely imposes additional heterogeneity within the BMME to yield differential clonal responses.A holistic understanding of the role of bone remodeling in regulating the stem cell niche and how these interactions are altered in age-related hematological malignancies will be critical to the development of novel *** advance this understanding,herein,we provide a synopsis of the cellular and molecular constituents that participate in bone turnover and their known connections to the hematopoietic ***,we elaborate on the coupling between bone remodeling and the BMME in homeostasis and age-related hematological malignancies and after treatment with bone-targeting *** then discuss unresolved questions and ambiguities that remain in the field.

关键词： remodeling homeostasis likely

Plastic multilayered closure versus orthopedic surgeon closure after spinal instrumentation in pediatric neuromuscular scoliosis

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Pediatric Surgery 2023年第1期6卷 30-35页

作者： Ekene U Ezeokoli Poornima L Tamma Neritan Borici Ifeoma Inneh edward P Buchanan Brian G Smith Department of Orthopedic Surgery Texas Children's HospitalHoustonTexasUSA Baylor College of Medicine HoustonTexasUSA Department of Plastic Surgery Texas Children's HospitalHoustonTexasUSA Department of Orthopedic Surgery Baylor College of MedicineHoustonTexasUSA

Objective To compare wound complication rates between orthopedic closure(OC)and plastic multilayered closure(PMC)in patients undergoing primary posterior spinal fusion for neuromuscular scoliosis(NMS).We hypothesize that multilayered closure will be associated with better postoperative *** We collected data on pediatric patients diagnosed with NMS who underwent first time spinal instrumentation between 1 January 2018 and 31 May *** demographics,length of surgery,spinal levels fused and operative variables,wound complication rate,treatments,and need for wound washout were reviewed in depth and *** In total,86 patients were reviewed:46 with OC and 40 with *** was a significant increase in operating room(OR)time with PMC compared with OC(6.7±1.2 vs 7.3±1.3,p=0.016).There was no difference in complication rate,mean postoperative day of complication or unplanned return to the OR for OC and PMC,*** was a slightly significant increase in the number of patients going home with a drain in the PMC cohort compared with the OC cohort(2.1%vs 15%,p=0.046).Conclusions PMC demonstrated longer OR times than OC and did not demonstrate a statistically significant reduction in wound complications or unplanned returns to the ***,other studies have demonstrated statistical and clinical significance with these *** programs should review internal patient volumes and outcomes for spinal fusion in NMS patients and consider if PMC after spinal fusions in pediatric patients with NMS or other scoliosis subtypes is an appropriate option in their institution to minimize postoperative wound complications.

关键词： wound pediatric closure

All-perovskite tandems go bifacial

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2023年第1期12卷 10-11页

作者： Suhas Mahesh Bin Chen edward H.Sargent The edward S.Rogers Department of Electrical and Computer Engineering University of TorontoTorontoON M5S 3G4Canada Department of Chemistry Northwestern UniversityEvanstonIL 60208USA Department of Electrical and Computer Engineering Northwestern UniversityEvanstonIL 60208USA

All-perovskite tandem cells are attractive candidates for next-generation photovoltaic technology as they hold the potential to combine high-efficiency with low weight and reduced energy-payback ***,researchers show that such tandem cells can be engineering to be bifacial,allowing them to utilize stray light reflected off the surrounding environment,resulting in a 17%boost in the power output.

关键词： utilize attractive perovskite