检索结果-南通市图书馆

Science China Mathematics 2019年第6期62卷 1029-1040页

作者： annalisa baldi Bruno Franchi Pierre Pansu Dipartimento di Matematica Università di Bologna Laboratoire de Mathématiques d'Orsay Université Paris-Sud CNRSUniversité Paris-Saclay

In this paper, we prove Poincaré and Sobolev inequalities for differential forms in L^1(R^n). The singular integral estimates that it is possible to use for L^p, p > 1, are replaced here with inequalities which go ba... 详细信息

关键词： differential forms Sobolev-Poincaré inequalities homotopy formula

A Recursive Basis for Primitive Forms in Symplectic Spaces and Applications to Heisenberg Groups

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2016年第3期32卷 265-285页

作者： annalisa baldi Marilena BARNABEI Bruno FRANCHI Dipartimento di Matematica Piazza di Porta S.Donato 540126 BolognaItaly

This paper is divided in two parts： in Section 2, we define recursively a privileged basis of the primitive forms in a symplectic space（V^（2n）, ω）. Successively, in Section 3, we apply our construction in the setting of Heisenberg groups H^n, n ≥ 1, to write in coordinates the exterior differential of the so-called Rumin＇s complex of differential forms in H^n.

关键词： Symplectic manifolds differential forms Heisenberg groups combinatorial functions

本刊英文版Vol.32(2016),No.4论文摘要（英文）

在线全文

学校读者我要写书评

暂无评论

数学学报（中文版） 2016年第3期59卷 I0004-I0006页

作者： annalisa baldi Marilena BARNABEI Bruno FRANCHI

A Khovanov Type Link Homology with Geometric Interpretation Mei Li ZHANG Feng Chun LEI Abstract We study a Khovanov type homology close to the original Khovanov homology theory from Frobenius *** homology is an invari... 详细信息

关键词：《数学学报》英文摘要期刊编辑工作

How dopamine tunes parvalbumin interneurons in the hippocampus:new experimental observations in Alzheimer's disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第5期20卷 1405-1406页

作者： Livia La Barbera Paraskevi Krashia annalisa Nobili Department of Medicine and Surgery UniversitàCampus Bio-Medico di RomaViaÁlvaro del PortilloRomeItaly Department of Experimental Neurosciences IRCCS Santa Lucia FoundationVia del Fosso di FioranoRomeItaly Department of Science and Technology for Sustainable Development and One Health UniversitàCampus Bio-Medico di RomaViaÁlvaro del PortilloRomeItaly

Despite decades of dedicated resea rch,Alzheimer's disease (AD) is an age-related and progressive neurodegenerative disorder for which the mechanisms of onset are sti unc *** is cha racterized by featured histological alterations including amyloid-beta (AB) plaque deposition,accumulation of neurofibrillary to ngles of hyperphosphorylated-tau,and neuronal loss,accompanied by progressive cognitive decline and behavioral changes.

关键词： Alzheimer alterations dopamine

Recognition and quality mapping of traditional herbal drugs:way forward towards artificial intelligence

在线全文

学校读者我要写书评

暂无评论

Traditional Medicine Research 2025年第1期10卷 12-26页

作者： Sanyam Sharma Subh Naman Ashish baldi Faculty of Pharmacy Pacific Academy of Higher Education and Research UniversityUdaipur 313024India Pharma Innovation Lab Department of Pharmaceutical Sciences and TechnologyMaharaja Ranjit Singh Punjab Technical UniversityBathinda 151001India Faculty of Pharmaceutical Sciences The ICFAI UniversityBaddi 174103India.

The use of traditional herbal drugs derived from natural sources is on the rise due to their minimal side effects and numerous health ***,a major limitation is the lack of standardized knowledge for identifying and mapping the quality of these herbal *** article aims to provide practical insights into the application of artificial intelligence for quality-based commercialization of raw herbal *** focuses on feature extraction methods,image processing techniques,and the preparation of herbal images for compatibility with machine learning *** article discusses commonly used image processing tools such as normalization,slicing,cropping,and augmentation to prepare images for artificial intelligence-based *** also provides an overview of global herbal image databases and the models employed for herbal plant/drug *** will gain a comprehensive understanding of the potential application of various machine learning models,including artificial neural networks and convolutional neural *** article delves into suitable validation parameters like true positive rates,accuracy,precision,and more for the development of artificial intelligence-based identification and authentication techniques for herbal *** article offers valuable insights and a conclusive platform for the further exploration of artificial intelligence in the field of herbal drugs,paving the way for smarter identification and authentication methods.

关键词： artificial intelligence Ayurveda machine learning models herbal drugs image pre-processing medicinal plants

Functional impacts of non-coding RNA processing on enhancer activity and target gene expression

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Molecular Cell Biology 2019年第10期11卷 868-879页

作者： Evgenia Ntini annalisa Marsico Max Planck Institute for Molecular Genetics 14195BerlinGermany Free University Berlin 14195BerlinGermany Institute of Computational Biology Helmholtz Zentrum MunchenMunchenGermany

Tight regulation of gene expression is orchestrated by *** recent research advancements,it is becoming clear that enhancers are not solely distal regulatory elements harboring transcription factor binding sites and decorated with specific histone marks,but they rather display sign atures of active transcription,showingdistinct degrees oftranscription unit ***,a substantial fraction of enhancers give rise to different species of non-coding RNA transcripts with an unprecedented range of potential *** this review,we bring together data from recent studies indicating that non-coding RNA transcription from active enhancers,as well as enhancer-produced long non-coding RNA transcripts,may modulate or define the functional regulatory potential ofthe cognate *** addition,we summarize supporting evidence that RNA processing ofthe enhancer-associated long non-coding RNA transcripts may constitute an additional layer of regulation of enhancer activity,which contributes to the control and final outcome of enhancer-targeted gene expression.

关键词： transcription enhancer RNA processing cotranscriptional RNA splicing chromatin long non-coding RNA(IncRNA)

Simple experimental procedures to distinguish photothermal from hot-carrier processes in plasmonics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2020年第1期9卷 974-989页

作者： Guillaume Baffou Ivan Bordacchini Andrea baldi Romain Quidant Institut Fresnel CNRSAix Marseille UniversityCentrale MarseilleMarseilleFrance ICFO-Institut de Ciencies Fotoniques The Barcelona Institute of Science and Technology08860CastelldefelsBarcelonaSpain DIFFER-Dutch Institute for Fundamental Energy Research De Zaale 205612 AJ EindhovenThe Netherlands Vrije Universiteit Amsterdam De Boelelaan 10811081 HV AmsterdamThe Netherlands ICREA-Institucio Catalana de Recerca i Estudis Avancats 08010 BarcelonaSpain Nanophotonic Systems Laboratory Department of Mechanical and Process EngineeringETH Zurich8092ZurichSwitzerland

Light absorption and scattering of plasmonic metal nanoparticles can lead to non-equilibrium charge carriers,intense electromagnetic near-fields,and heat generation,with promising applications in a vast range of fields,from chemical and physical sensing to nanomedicine and photocatalysis for the sustainable production of fuels and *** the relative contribution of thermal and non-thermal contributions in plasmon-driven processes is,however,*** temperature measurements are technically challenging,and macroscale experiments are often characterized by collective heating effects,which tend to make the actual temperature increase *** work is intended to help the reader experimentally detect and quantify photothermal effects in plasmon-driven chemical reactions,to discriminate their contribution from that due to photochemical processes and to cast a critical eye on the current *** this aim,we review,and in some cases propose,seven simple experimental procedures that do not require the use of complex or expensive thermal microscopy *** proposed procedures are adaptable to a wide range of experiments and fields of research where photothermal effects need to be assessed,such as plasmonic-assisted chemistry,heterogeneous catalysis,photovoltaics,biosensing,and enhanced molecular spectroscopy.

关键词： collective photochemical intense

On the Numerical Solution to a Nonlinear Wave Equation Associated with the First Painlev Equation:an Operator-Splitting Approach

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Annals of Mathematics,Series B 2013年第2期34卷 237-254页

作者： Roland GLOWINSKI annalisa QUAINI Department of Mathematics University of Houston4800 Calhoun RdHouston(TX) 77204USA Laboratoire Jacques-Louis Lions Universit Pierre et Marie Curie4Place Jussieu75252 Paris CEDEX 05France

The main goal of this article is to discuss the numerical solution to a nonlinear wave equation associated with the first of the celebrated Painlevd transcendent ordinary differential equations. In order to solve numerically the above equation, whose solutions blow up in finite time, the authors advocate a numerical methodology based on the Strang＇s symmetrized operator-splitting scheme. With this approach, one can decouple nonlinearity and differential operators, leading to the alternate solution at every time step of the equation as follows：（i） The first Painlevd ordinary differential equation, （ii） a linear wave equation with a constant coefficient. Assuming that the space dimension is two, the authors consider a fully discrete variant of the above scheme, where the space-time discretization of the linear wave equation sub-steps is achieved via a Galerkin/finite element space approximation combined with a second order accurate centered time discretization scheme. To handle the nonlinear sub-steps, a second order accurate centered explicit time discretization scheme with adaptively variable time step is used, in order to follow accurately the fast dynamic of the solution before it blows up. The results of numerical experiments are presented for different coefficients and boundary conditions. They show that the above methodology is robust and describes fairly accurately the evolution of a rather ＂violent＂ phenomenon.

关键词： Painlevd equation Nonlinear wave equation Blow-up solution Operator-SDlitting

The FAIR Funding Model:Providing a Framework for Research Funders to Drive the Transition toward FAIR Data Management and Stewardship Practices

在线全文

学校读者我要写书评

暂无评论

Data Intelligence 2020年第1期2卷 171-180,314页

作者： Margreet Bloemers annalisa Montesanti The Netherlands Organization for Health Research and Development(ZonMw) 2509 AEThe HagueThe Netherlands Health Research Board(HRB) Dublin 2DO2 H638Ireland

A growing number of research funding organizations(RFOs)are taking responsibility to increase the scientific and social impact of research *** reusable research data are recognized as relevant output for gaining *** are therefore promoting FAIR research data management and stewardship(RDM)in their research funding ***,the implementation of FAIR RDM still faces important obstacles and *** solve these,stakeholders work together to develop innovative tools and *** we elaborate on the role of RFOs in developing a FAIR funding model to support the FAIR RDM in the funding cycle,integrated with research community specific guidance,criteria and metadata,and enabling automatic assessments of progress and output from *** model facilitates to create research data with a high level of FAIRness that are meaningful for a research *** fully benefit from the model,RFOs,research institutions and service providers need to implement machine actionability in their FAIR RDM tools and *** many stakeholders still need to get familiar with“human actionable”FAIR data practices,the introduction of the model will be stepwise,with an active role of the RFOs in driving FAIR RDM processes as effectively as possible.

关键词： FAIR funder Data stewardship Data management plan(DMP) Policy Tools

Targeting endothelial cell metabolism： new therapeutic prospects？

在线全文

学校读者我要写书评

暂无评论

Frontiers in Biology 2015年第2期10卷 125-140页

作者： annalisa Zecchin Laboratory of Angiogenesis and Neurovascular Link Vesalius Research Center VIB Leuven Belgium Laboratory of Angiogenesis and Neurovaseular Link Department of Oncology KU Leuven Leuven Belgium

Endothelial cells （ECs） line blood vessels and function as a vital conduit for oxygen and nutrients, but can also form vascular niches for various types of stem cells. While mostly quiescent throughout adult life, ECs can rapidly switch to a highly active state, and start to sprout in order to form new blood vessels. ECs can also become dysfunctional, as occurs in diabetes and atherosclerosis. Recent studies have demonstrated a key role for EC metabolism in the regulation of angiogenesis, and showed that EC metabolism is even capable of overriding genetic signals. In this review, we will review the basic principles of EC metabolism and focus on the metabolic alterations that accompany EC dysfunction in diabetes and vessel overgrowth in cancer. We will also highlight how EC metabolism influences EC behavior by modulating post-translational modification and epigenetic changes, and illustrate how dietary supplementation of metabolites can change EC responses. Finally, we will discuss the potential of targeting EC metabolism as a novel therapeutic strategy.

关键词： angiogenesis metabolism endothelial cell dysfunction anti-angiogenic therapy