How dopamine tunes parvalbumin interneurons in the hippocampus:new experimental observations in Alzheimer's disease
作者机构:Department of Medicine and SurgeryUniversitàCampus Bio-Medico di RomaViaÁlvaro del PortilloRomeItaly Department of Experimental NeurosciencesIRCCS Santa Lucia FoundationVia del Fosso di FioranoRomeItaly Department of Science and Technology for Sustainable Development and One HealthUniversitàCampus Bio-Medico di RomaViaÁlvaro del PortilloRomeItaly
出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))
年 卷 期:2025年第20卷第5期
页 面:1405-1406页
核心收录:
学科分类:1002[医学-临床医学] 100203[医学-老年医学] 10[医学]
基 金:supported by an under-40 grant from the Italian Association for Alzheimer’s Research [AIRALZH AGYR2021] the Strategic University Projects–Young Researcher Independence grant [YRG2021] from the Università Campus Bio-Medico di Roma (Rome, Italy)(to LLB) Italian Ministry of Health [Research Grant:GR-2019-12370446] the American Alzheimer’s Association [AARG-22-922961](to PK)
主 题:Alzheimer alterations dopamine
摘 要:Despite decades of dedicated resea rch,Alzheimer s disease (AD) is an age-related and progressive neurodegenerative disorder for which the mechanisms of onset are sti unc *** is cha racterized by featured histological alterations including amyloid-beta (AB) plaque deposition,accumulation of neurofibrillary to ngles of hyperphosphorylated-tau,and neuronal loss,accompanied by progressive cognitive decline and behavioral changes.