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吸尘装置颗粒物冲蚀磨损特性数值分析

机械设计与制造 2021年第5期 199-203页

作者：郗元刘万渤张西龙代岩大连理工大学盘锦产业技术研究院辽宁省化学助剂合成与分离省市共建重点实验室辽宁盘锦124221 山东华夏神舟新材料有限公司山东东岳集团含氟功能膜材料国家重点实验室山东淄博255000 青岛理工大学机械与汽车工程学院山东青岛266520

为探究道路除尘装备吸尘装置作业时受颗粒物冲蚀磨损特性,采用计算流体动力学(CFD)方法和离散相模型(DPM),研究气固两相流作用下颗粒对其磨损特性。结果表明:颗粒物对内隔板、管路和四周隔板均产生不同程度磨损,其中壁面最大冲蚀磨损率... 详细信息

为探究道路除尘装备吸尘装置作业时受颗粒物冲蚀磨损特性,采用计算流体动力学(CFD)方法和离散相模型(DPM),研究气固两相流作用下颗粒对其磨损特性。结果表明:颗粒物对内隔板、管路和四周隔板均产生不同程度磨损,其中壁面最大冲蚀磨损率出现在吸尘腔左侧。气固两相流冲蚀率计算中,Genenic算法准确性较高,而Finnie算法计算的冲蚀率最大值和平均值均偏低,McLaury和Oka算法计算的冲蚀率波动幅度较大。针对冲蚀磨损最严重的吸尘管,提出增加其上下径比的改进方案。优化后,吸尘管路最大和平均冲蚀磨损率均实现降低,抗冲蚀效果实现提升。

关键词：计算流体力学气动循环吸尘装置颗粒物冲蚀磨损

Recognition of high-specificity hERG K+ channel inhibitor-induced arrhythmia in cardiomyocytes by automated template matching

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Microsystems & Nanoengineering 2021年第2期7卷 107-119页

作者： Hao Wang Hongbo Li xinwei Wei Tao Zhang Yuting xiang Jiaru Fang Peiran Wu xi xie Ping Wang Ning Hu The First Affiliated Hospital of Sun Yat-sen university School of Electronics and Information TechnologyState Key Laboratory of Optoelectronic Materials and TechnologiesGuangdong Province Key Laboratory of Display Material and TechnologySun Yat-sen UniversityGuangzhou510006China Biosensor National Special Laboratory Key Laboratory of Biomedical Engineering of Ministry of EducationDepartment of Biomedical EngineeringZhejiang UniversityHangzhou310027China The Sixth Affiliated Hospital of Sun Yat-sen university Guangzhou510655China state key Laboratory of Transducer Technology Chinese Academy of SciencesShanghai200050China

Cardiovascular disease(CVD)is the number one cause of death in *** induced by gene mutations,heart disease,or hERG K+channel inhibitors is a serious CVD that can lead to sudden death or heart *** cardiomyocyte-based biosensors can record extracellular potentials and mechanical beating ***,parameter extraction and examination by the naked eye are the traditional methods for analyzing arrhythmic beats,and it is difficult to achieve automated and efficient arrhythmic recognition with these *** this work,we developed a unique automated template matching(ATM)cardiomyocyte beating model to achieve arrhythmic recognition at the single beat level with an interdigitated electrode impedance detection *** ATM model was established based on a rhythmic template with a data length that was dynamically adjusted to match the data length of the target beat by spline *** performance of the ATM model under long-term astemizole,droperidol,and sertindole treatment at different doses was *** results indicated that the ATM model based on a random rhythmic template of a signal segment obtained after astemizole treatment presented a higher recognition accuracy(100%for astemizole treatment and 99.14.for droperidol and sertindole treatment)than the ATM model based on arrhythmic *** believe this highly specific ATM method based on a cardiomyocyte beating model has the potential to be used for arrhythmia screening in the fields of cardiology and pharmacology.

关键词： channel template matching

Identification of Px APN5 serve as a functional receptor of Cry2Ab in Plutella xylostella

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Identification of Px APN5 serve as a functional receptor of ...

Osteogenic fate of hypertrophic chondrocytes

中国生物化学与分子生物学会2016年全国学术会议

作者： Yu-Jing Zhu Lian Xu Zhi-Zhen Pan Qing-xi Chen Bo Liu Agricultural Bio-Resources Research Institute Fujian Academy of Agricultural Sciences state key Laboratory of Cellular Stress Biology Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystems School of Life Sciences Xiamen University

Insecticidal activities of Cry toxins relied on their interaction with midgut receptors inlaying in the brush border membrane vesicles(BBMV)of target *** present study,we demonstrated that an aminopeptidase N(Px APN5)... 详细信息

关键词： Bacillus thuringiensis Cry2Ab toxin Plutella xylostella aminopeptidase N RNAi ligand blot

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Osteogenic fate of hypertrophic chondrocytes

Low light intensity elongates period and defers peak time of photosynthesis: a computational approach to circadian-clock-controlled photosynthesis in tomato

2015中国遗传学会大会

作者：杨冠朱良 Ning Hou Yu Lan xi-Mei Wu Bin Zhou 滕艳杨晓 state key Laboratory of Proteomics Genetic Laboratory of Development and DiseasesInstitute of Biotechnology Department of Pharmacology School of MedicineZhejiang University key Laboratory of Nutrition and Metabolism Institute for Nutritional SciencesShanghai Institutes for Biological SciencesGraduate School of the Chinese Academy of SciencesChinese Academy of Sciences

Endochondral bone formation is largely dependent on cartilage lineage *** chondrocytes in growth plates continuously undergo a sequential process from proliferation to terminal hypertrophic *** differentiated,hypertrophic chondrocytes elicit multiple functions such as determining bone length,inducing osteogenesis as well as directing bone mineralization,and eventually disappear at the chondro-osseous *** fate of the terminally differentiated hypertrophic chondrocytes is conceptually important for understanding its role in endochondral bone *** has been debated for decades whether the terminally differentiated hypertrophic chondrocytes die by apoptosis or undergo osteogenic transdifferentiation,however,clear in vivo evidence is ***,through lineage tracing,we provide the first in vivo evidence that the terminally differentiated hypertrophic chondrocytes are a potent source of osteoblasts,and retain multi-lineage differentiation potential.

关键词： lineage tracing hypertrophic chondrocytes fate osteoblasts multi-lineage differentiation

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Horticulture Research 2023年第6期10卷 121-134页

作者： Ting Huang Hui Liu Jian-Ping Tao Jia-Qi Zhang Tong-Min Zhao xi-Lin Hou Ai-Sheng xiong xiong You College of Horticulture Nanjing Agricultural University/State Key Laboratory of Crop Genetics and Germplasm Enhancement/Key Laboratory of Horticultural Crop Biology and Germplasm Creation in East China of Ministry of Agriculture and Rural Affairs Nanjing 210095JiangsuChina The Institute of Agricultural Information Jiangsu Province Academy of Agricultural SciencesNanjing 210014JiangsuChina Laboratory for Genetic Improvement of High Efficiency Horticultural Crops in Jiangsu Province Institute of Vegetable CropJiangsu Province Academy of Agricultural SciencesNanjing 210014JiangsuChina College of Sciences Nanjing Agricultural UniversityNanjing 210095Jiangsu China

Photosynthesis is involved in the essential process of transforming light energy into chemical *** the interaction between photosynthesis and the circadian clock has been confirmed,the mechanism of how light intensity affects photosynthesis through the circadian clock remains ***,we propose a first computational model for circadian-clock-controlled photosynthesis,which consists of the light-sensitive protein P,the core oscillator,photosynthetic genes,and parameters involved in the process of *** model parameters were determined by minimizing the cost function(δ=8.56),which is defined by the errors of expression levels,periods,and phases of the clock genes(CCA1,PRR9,TOC1,ELF4.GI,and RVE8).The model recapitulates the expression pattern of the core oscillator under moderate light intensity(100μmol m^(-2) s^(-1)).Further simulation validated the dynamic behaviors of the circadian clock and photosynthetic outputs under low(62.5μmol m^(-2) s^(-1))and normal(187.5μmol m^(-2) s^(-1))*** exposed to low light intensity,the peak times of clock and photosynthetic genes were shifted backward by 1–2 hours,the period was elongated by approximately the same length,and the photosynthetic parameters attained low values and showed delayed peak times,which confirmed our model *** study reveals a potential mechanism underlying the circadian regulation of photosynthesis by the clock under different light intensities in tomato.

关键词： period intensity light

Excited state biexcitons in monolayer WSe_(2)driven by vertically grown graphene nanosheets with high-density electron trapping edges

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Frontiers of physics 2023年第3期18卷 103-112页

作者： Bo Wen Da-Ning Luo Ling-Long Zhang xiao-Lin Li xin Wang Liang-Liang Huang xi Zhang Dong-Feng Diao Institute of Nanosurface Science and Engineering Guangdong Provincial key Laboratory of Micro/Nano Optomechatronics Engineering Shenzhen UniversityShenzhen 518060China College of Physics Nanjing University of Aeronautics and AstronauticsKey Laboratory of Aerospace Information Materials and Physics(NUAA)MIITNanjing 211106China Research Center of Medical Plasma Technology Shenzhen UniversityShenzhen 518060China

Interface engineering in atomically thin transition metal dichalcogenides(TMDs)is becoming an important and powerful technique to alter their properties,enabling new optoelectronic applications and quantum *** engineering in a monolayer WSe_(2)sample via introduction of high-density edges of standing structured graphene nanosheets(GNs)is realized.A strong photoluminescence(PL)emission peak from intravalley and intervalley trions at about 750 nm is observed at the room temperature,which indicated the heavily p-type doping of the monolayer WSe_(2)/thin graphene nanosheet-embedded carbon(TGNEC)film *** also successfully triggered the emission of biexcitons(excited state biexciton)in a monolayer WSe_(2),via the electron trapping centers of edge quantum wells of a TGNEC *** PL emission of a monolayer WSe_(2)/GNEC film is quenched by capturing the photoexcited electrons to reduce the electron-hole recombination *** study can be an important benchmark for the extensive understanding of light–matter interaction in TMDs,and their dynamics.

关键词： excited state biexcitons monolayer WSe_(2) vertically graphene electron trapping edges

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基于贝叶斯估计的漏磁缺陷轮廓重构方法研究

兵工学报 2012年第1期33卷 116-120页

作者：苑希超王长龙王建斌军械工程学院电气工程系河北石家庄050003

漏磁缺陷轮廓重构是指由检测到的漏磁信号重构缺陷轮廓及参数,是实现漏磁反演的关键。目前常用的反演方法包括神经网络法和优化法,但神经网络法的计算精度受噪声影响严重,优化法计算量大。针对这些问题,提出基于递推贝叶斯估计的漏磁缺... 详细信息

漏磁缺陷轮廓重构是指由检测到的漏磁信号重构缺陷轮廓及参数,是实现漏磁反演的关键。目前常用的反演方法包括神经网络法和优化法,但神经网络法的计算精度受噪声影响严重,优化法计算量大。针对这些问题,提出基于递推贝叶斯估计的漏磁缺陷重构算法。建立缺陷轮廓与漏磁信号的状态空间模型,将反演问题描述为基于状态和观测方程的典型的离散时间跟踪问题,对漏磁信号进行了反演,并在不同信噪比下对神经网络法和所提方法进行了反演效果的比较。结果表明:基于递推贝叶斯估计方法的漏磁信号反演算法精度高,同时对噪声具有鲁棒性,是一种有效可行的漏磁反演新方法。

关键词：电磁学漏磁检测轮廓重构粒子滤波重采样

Programmable dual responsive system reconstructing nerve interaction with small-diameter tissue-engineered vascular grafts and inhibiting intimal hyperplasia in diabetes

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Bioactive Materials 2022年第1期7卷 466-477页

作者： Yanzhao Li Yeqin Wang Fangchao Xue Xuli Feng Zhaojing Ba Junjie Chen Zhenhua Zhou Yanhong Wang Ge Guan Guanyuan Yang Ziwei xi Hao Tian Yong Liu Ju Tan Gang Li xiewan Chen Mingcan Yang Wen Chen Chuhong Zhu Wen Zeng Department of Anatomy National and Regional Engineering Laboratory of Tissue EngineeringState and Local Joint Engineering Laboratory for Vascular ImplantsKey Lab for Biomechanics and Tissue Engineering of ChongqingThird Military Medical UniversityChongqing400038China Department of Cell Biology Third Military Army Medical UniversityChongqing400038China Innovative Drug Research Centre of Chongqing university Chongqing401331China Departments of Neurology Southwest HospitalThird Military Medical UniversityChongqingChina Medical English Department Third Military Medical UniversityChongqing400038China The 8th Medical Center of Chinese PLA General Hospital Beijing100091China Department of Plastic and Aesthetic Surgery Southwest HospitalThird Military Medical UniversityChongqingChina state key Laboratory of Trauma Burn and Combined InjuryChongqingChina

Small-diameter tissue-engineered vascular grafts(sdTEVGs)with hyperglycemia resistance have not been *** intimal hyperplasia caused by hyperglycemia remains problem to hinder the patency of ***,inspired by bionic regulation of nerve on vascular,we found the released neural exosomes could inhibit the abnormal phenotype transformation of vascular smooth muscle cells(VSMCs).The transformation was a prime culprit causing the intimal hyperplasia of *** address this concern,sdTEVGs were modified with an on-demand programmable dual-responsive system of ultrathin *** external primary Reactive Oxygen Species(ROS)-responsive Netrin-1 system was initially triggered by local inflammation to induce nerve remolding of the sdTEVGs overcoming the difficulty of nerve regeneration under ***,the internal secondary ATP-responsive DENND1A(guanine nucleotide exchange factor)system was turned on by the neurotransmitter ATP from the immigrated nerve fibers to stimulate effective release of neural *** results showed nerve fibers grow into the sdTEVGs in diabetic rats 30 days after *** day 90,the abnormal VSMCs phenotype was not detected in the sdTEVGs,which maintained long-time patency without intima *** study provides new insights to construct vascular grafts resisting hyperglycemia damage.

关键词： sdTEVGs On-demand programmed responsive systems Neural exosomes Nerve reconstruction Intimal hyperplasia

白腹鹭CO I和Cyt b基因序列分析及鹭属系统发育研究

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四川动物 2018年第3期37卷 268-273页

作者：陈熙王斌罗旭西南林业大学西南地区生物多样性保育国家林业局重点实验室昆明650224 云南高黎贡山国家级自然保护区泸水管护分局云南泸水673100

白腹鹭Ardea insignis数量稀少,被世界自然保护联盟列为极危(CR)物种,关于该物种的生态信息和分子生物学研究极少。本研究通过扩增得到了白腹鹭的2个线粒体基因序列(CO I和Cyt b),Cyt b基因序列长度为1 163 bp,其中的A+T含量(51.7%)高于... 详细信息

白腹鹭Ardea insignis数量稀少,被世界自然保护联盟列为极危(CR)物种,关于该物种的生态信息和分子生物学研究极少。本研究通过扩增得到了白腹鹭的2个线粒体基因序列(CO I和Cyt b),Cyt b基因序列长度为1 163 bp,其中的A+T含量(51.7%)高于C+G(4..3%),第三位点上碱基偏倚最突出;CO I基因序列长度为722 bp,A+T含量(52.5%)高于C+G(4..5%),碱基偏倚同样在第三位点最明显。结合来自Gen Bank鹭属Ardea其他6个物种的CO I和Cyt b基因序列,构建鹭属的系统发育树,结果表明,鹭属7种鸟类构成单系,后验概率支持度为96%,大白鹭***和白腹鹭在鹭属中是较早分化出的类群,位于鹭属分支的基部;白腹鹭与草鹭***的遗传距离最近。

关键词：白腹鹭 CO I基因 Cyt b基因系统发育树