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Antioxidant activities of Indigofera cassioides *** various in vitro assay models

Antioxidant activities of Indigofera cassioides *** various in vitro assay models

作     者:R Senthil Kumar B Rajkapoor P Perumal 

作者机构:Natural Products LaboratorySwamy Vivekanandha College of Pharmacy Department of PharmacologyDayanandha Sagar College of Pharmacy Department of Pharmaceutical ChemistryJKK Nataraja College of Pharmacy 

出 版 物:《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志(英文版))

年 卷 期:2012年第2卷第4期

页      面:256-261页

学科分类:0710[理学-生物学] 0831[工学-生物医学工程(可授工学、理学、医学学位)] 1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

主  题:Indigofera cassioides Antioxidant Free radicals Oxidative stress Total reducing power Free radical scavenging activity 

摘      要:Objective:To evaluate the antioxidant potential of methanolic leaf extract of Indigofera cassioides(MEIC) using various in vilro antioxidant assay ***:Antioxidant and free radical scavenging activity of MEIC was assayed by using different in vitro models like ABTS, DPPH,nitric oxide,superoxide,hydrogen peroxide and hydroxyl *** ability of the extract was tested by the complex formation with potassium *** total phenol and flavonoid contents of the crude extract were also *** and ascorbic acid were used as ***:MEIC exhibited potent and concentration dependent free radical scavenging activity in all the tested *** ability was also found to increase with increase in MEIC *** phenol and flavonoid content determination showed that the extract is rich in phenols and ***:All the results of the in vitro antioxidant assays reveal potent antioxidant and free radical scavenging activity of the leaves of Indigofera cassioides,equivalent to that of standard ascorbic acid and *** potent antioxidant activity may be attributed to its high phenolic and flavonoid contents.

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