Associations between Vaspin Levels and Coronary Artery Disease
作者机构:Department of CardiologyAdiyaman Education and Research HospitalAdiyamanTurkey
出 版 物:《Cardiovascular Innovations and Applications》 (心血管创新与应用(英文))
年 卷 期:2020年第4卷第1期
页 面:211-216页
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题:adipokine atherosclerosis infl ammation coronary artery disease vaspin
摘 要:The relationship between serum vaspin levels and metabolic or coronary artery disease is currently of interest for *** adipokine concentrations have been shown to be increased signifi cantly in atherosclerotic lesions,the role adipokines in the atherosclerotic process remains to be *** is a new biological marker associated with obesity and impaired insulin *** vaspin concentration has been shown to correlate with the severity of coronary artery *** infl ammation triggered by vaspin inhibits atherogenesis by suppressing macrophage foam cell formation and vascular smooth muscle cell migration and *** also contributes to plaque stabilization by increasing collagen content and reducing the intraplaque macrophage to vascular smooth muscle cell *** therapeutic goal concerning vaspin is to fi ght atherosclerosis and related diseases,as well as to maintain vascular health.