Fabrication and Characterization of Poly Lactic Acid Scaffolds by Fused Deposition Modeling for Bone Tissue Engineering

作     者：Mohammad Khodaei Kamran Amini Alireza Valanezhad Mohammad Khodaei;Kamran Amini;Alireza Valanezhad

作者机构：Department of Materials Science and EngineeringGolpayegan University of TechnologyGolpayeganIran Department of Materials EngineeringTiran BranchIslamic Azad UniversityIsfahanIran Center for Advanced Engineering ResearchMajlesi BranchIslamic Azad UniversityIsfahanIran Department of Dental and Biomedical Materials ScienceNagasaki UniversityNagasakiJapan 

出 版 物：《Journal of Wuhan University of Technology(Materials Science)》 (武汉理工大学学报（材料科学英文版）)

年 卷 期：2020年第35卷第1期

页      面：248-251页

核心收录：

学科分类：08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

主　　题：3D porous scaffold fused deposition modeling poly-lactic acid biodegradable polymer 

摘      要：Three-dimensional porous poly-lactic acid(PLA) scaffold was fabricated using fused deposition modeling(FDM) method including 30%, 50% and 70% nominal porosity. Study of phases in initial polymeric material and printed scaffolds was done by X-ray diffraction(XRD), and no significant phase difference was observed due to the manufacturing process, and the poly-lactic acid retains its crystalline properties. The results of the mechanical properties evaluation by the compression test show that the mechanical properties of the scaffold have decreased significantly with increasing the porosity of scaffold. The microstructure of scaffolds were studied by scanning electron microscope(SEM), showing that the pores had a regular arrangement and their morphology changed with porosity change. The mechanical properties of the poly-lactic acid scaffolds printed using fused deposition modeling, can be adapted to the surrounding tissue, by porosity change.