Practical Clinical Application of Cardiac Computed Tomography– Derived Fractional Flow Reserve

作     者：Talal Alzahrani,MD Ahmed Tashkandi,MD Abdullah Sarkar,MD Claudio Smuclovisky,MD James P.Earls,MD Andrew D.Choi,MD 

作者机构：Division of CardiologyThe George Washington University School of MedicineWashingtonDCUSA Department of MedicineUniversity of MiamiMiamiFLUSA Diagnostic Imaging CenterHoly Cross HospitalFort LauderdaleFLUSA Department of RadiologyThe George Washington University School of MedicineWashingtonDCUSA 

出 版 物：《Cardiovascular Innovations and Applications》 (心血管创新与应用（英文）)

年 卷 期：2019年第4卷第B4期

页      面：31-42页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：coronary artery disease cardiac computed tomography fractional fl ow reserve fractional fl ow reserve derived by computed tomography Ischemia 

摘      要：In the past decade,advances in coronary computed tomography angiography(CTA)technology have resulted in high sensitivity and negative predictive value in detecting coronary artery disease(CAD)compared with invasive coronary angiography,particularly for patients with mild or severe ***,anatomical evaluation of CAD by CTA has modest specifi city for patients with intermediate-grade *** recent development of the use of cardiac computed tomography– derived fractional fl ow reserve(FFR-CT)seeks to address this gap as a proposed method of functional assessment of CAD by *** this article we aim to mix common clinical cases with the current technical methods,validation,outcomes,and registry studies as well as the technical,fi nancial and research limitations of FFRCT analysis to guide the cardiac imaging specialist in evaluating this ***-CT analysis may help reduce additive functional testing for the smaller proportion of patients with intermediate stenosis undergoing coronary CTA where the atherosclerosis signifi cance is uncertain.