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An epigenetic regulatory switch controlling temperature-dependent sex determination in vertebrates

An epigenetic regulatory switch controlling temperature-dependent sex determination in vertebrates

作     者:Xi-Yin Li Jian-Fang Gui 

作者机构:State Key Laboratory of Freshwater Ecology and Biotechnology Institute of Hydrobiology The Innovative Academy of Seed Design Chinese Academy of Sciences Wuhan 430072 China University of Chinese Academy of sciences Beijing 100049 China 

出 版 物:《Science China(Life Sciences)》 (中国科学(生命科学英文版))

年 卷 期:2018年第61卷第8期

页      面:996-998页

核心收录:

学科分类:0710[理学-生物学] 07[理学] 0905[农学-畜牧学] 09[农学] 071007[理学-遗传学] 090501[农学-动物遗传育种与繁殖] 

主  题:脊椎动物 温度依赖 开关控制 性别 规章 环境性 Gui ESD 

摘      要:Most vertebrates present two sexes, and females and males are determined via two diverse strategies including geno-typic sex determination (GSD) and environmental sex de-termination (ESD) (Mei and Gui, 2015; Ma et al., 2016). The most common form of ESD is temperature-dependent sex determination (TSD). Although several master sex-de-termining genes and their molecular pathways have been elucidated in vertebrates with GSD, the molecular mechan-ism underlying TSD remains unclear (Bachtrog et al., 2014; Capel, 2017).

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