Biological reaction signal enhancement in porous silicon Bragg mirror based on quantum dots fluorescence
Biological reaction signal enhancement in porous silicon Bragg mirror based on quantum dots fluorescence作者机构:School of Physical Science and TechnologyXinjiang UniversityUrumqi 830046China School of Information Science and EngineeringXinjiang UniversityUrumqi 830046China
出 版 物:《Optoelectronics Letters》 (光电子快报(英文版))
年 卷 期:2017年第13卷第3期
页 面:172-174页
核心收录:
学科分类:080202[工学-机械电子工程] 08[工学] 0802[工学-机械工程]
基 金:supported by the National Natural Science Foundation of China(Nos.61575168 and 61665012) the Xinjiang Science and Technology Project(No.201412112)
主 题:mirror Bragg biosensor biotin labeled detecting verified porous affinity streptavidin
摘 要:In this paper, we mainly study the preparation of an optical biosensor based on porous silicon(PSi) Bragg mirror and its feasibility for biological detection. The quantum dot(QD) labeled biotin was pipetted onto streptavidin functionalized PSi Bragg mirror samples, the affinity reaction between QD labeled biotin and streptavidin in PSi occurred, so the QDs were indirectly connected to the PSi. The fluorescence of QD enhanced the signal of biological reactions in PSi. The performance of the sensor is verified by detecting the fluorescence of the QD in PSi. Due to the fluorescence intensity of the QDs can be enhanced by PSi Bragg mirror, the sensitivity of the PSi optical biosensor will be improved.