Characterization of MT-2 cells as a human regulatory 7 cell-like cell line

作     者：Ryoko Hamano Xueqiang Wu Yitao Wang Joost J Oppenheim Xin Chen 

作者机构：Laboratory of Molecular Immunoregulation Cancer Inflammation Program Center for Cancer Research NCI Frederick MD USA Division of Rheumatology Kanazawa University Kanazawa Ishikawa Japan State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical Sciences University of Macao Macao SAR China 

出 版 物：《Cellular & Molecular Immunology》 (中国免疫学杂志（英文版）)

年 卷 期：2016年第13卷第1期

页      面：132-134页

核心收录：

学科分类：0710[理学-生物学] 12[管理学] 1204[管理学-公共管理] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 0905[农学-畜牧学] 09[农学] 090501[农学-动物遗传育种与繁殖] 

基　　金：supported (in part) by the Intramural Research Program of the NIH  National Cancer Institute  Center for Cancer Research and (in part) by the University of Macau 

主　　题：eg细胞 人类 调控 表征 调节性T细胞 分离鉴定 分子基础 细胞功能 

摘      要：The paucity of naturally occurring CD4^＋FoxP3^＋ regulatory T cells （Tregs） and difficulties in the identification and isolation of such cells are major obstacles in the study of human Tregs. The availability of human Treg-like cell lines is likely to facilitate a better understanding of the molecular basis of Treg function and aid the discovery of pharmacological reagents to regulate Treg activity in a disease state.