FamilyCoviDD19: results of a cross-sectional study—long-term outcomes of infected and uninfected household members

作     者：Theresa S Horst Jakob P Armann Maren Doenhardt Svenja Dresen Paula Czyborra Josephine Schneider Christin Gano Alexander Dalpke Christian Luck Annet Bluschke Magdalena Wekenborg Reinhard Berner Judith Blankenburg 

作者机构：Department of PediatricsUniversity Hospital and Medical Faculty Carl Gustav CarusTechnische UniversitatDresdenDresdenGermany Department of Infectious DiseasesMedical Microbiology and HygieneUniversity Hospital HeidelbergHeidelbergGermany Institute of Medical Microbiology and VirologyUniversity Hospital and Medical Faculty Carl Gustav CarusTechnische UniversitatDresdenDresdenGermany Department of Child and Adolescent PsychiatryUniversity Hospital and Medical Faculty Carl Gustav CarusTechnische UniversitatDresdenDresdenGermany Biological PsychologyTechnische UniversitatDresdenDresdenGermany Else Kroner Fresenius Center for Digital HealthUniversity Hospital and Medical Faculty Carl Gustav CarusTechnische UniversitatDresdenDresdenGermany 

出 版 物：《Family Medicine and Community Health》 (家庭医学与社区卫生（英文）)

年 卷 期：2023年第11卷第3期

页      面：31-44页

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：This study was supported by a grant by the Federal State of Saxony grant name PAEDDAXCOVIDD 

主　　题：infected sectional consequences 

摘      要：Objective In this study,we aimed to compare long-term physical and mental health outcome between SARS-CoV-2 infected and uninfected household members to differentiate between infection-related and pandemic-related outcomes after about two and a half years of the ***,possible differences in the outcome of adults and children and young people(CYP)were of *** In a cross-sectional study design,we compared the long-term physical and mental health outcome of between infected and uninfected as well as between adult and CYP(household members).Setting The FamilyCoviDD19 study—a serology study in households—was initially conducted to evaluate virus transmission in a close contact setting focusing on households with children and adolescents in *** least 1year after initial infection in the respective households,a follow-up took place in which the prevalence and type of possible long-term consequences were surveyed on the basis of self-reported information on physical and mental *** In this study,a total of 533 household members of 146 families participated and responded to our survey,including 296(55.5%)adults and 237(44.5%)*** The difference in frequency of reported symptoms between infected and uninfected individuals was very moderate,suggesting that the vast majority of reported symptoms were not attributable to a previous SARS-CoV-2 ***,regardless of age and infection status,this study showed overall high rates of self-reported symptoms with CYP having fewer long-term sequelae than adults oneyear after ***,over 50%of those reporting symptoms were not affected in their daily life,with CYPs reporting an even lower percentage compared with *** CYP are at reduced risk not only to develop symptomatic infection or severe disease courses(previous analyses)but also to develop infection-associated long-term sequelae(this study).Independent of infection CYP reported high rates of